Clinical trials
Depression, Anxiety clinical trials
Below are recruiting depression, anxiety clinical trials, each written for real people, not researchers. We’re tracking 481 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06604104Recruiting
Visual Frailty Study in Older Adults with AMD
This study looks at something called 'visual frailty' in older adults with advanced age-related macular degeneration (AMD). It aims to develop a tool to better understand how vision loss affects daily life and overall health in people aged 60 and over.
Edinburgh, ScotlandAges 60 years+ - NCT06606249Recruiting
Self-help coping skills for stressed university students
This trial tests a self-guided program, Self-Help Plus, to help university students manage stress and catch up with their studies. It may be helpful if you are behind on exams and feeling distressed.
Bari, BariAges 18 years+ - NCT06627764Recruiting
Family program for Latino immigrant families with teens
This study tests a family-based program to help Latino immigrant parents and their teenagers (ages 12-17) build stronger relationships and address challenges together. It is designed for first-generation immigrant families who speak English or Spanish.
Durham, North CarolinaAges 12–100 - NCT06633146Recruiting
Stroke rehab in nature settings
This trial tests if stroke recovery exercises in natural environments can help improve your rehabilitation. It is for people who have had a recent stroke.
LahtiAges 18 years+ - NCT06646900Recruiting
Testing a culturally adapted CBT vs. standard CBT
This study tests whether a version of cognitive behavioral therapy (CBT) that is specially adapted for people in Pakistan works better than standard CBT. If you have depression or anxiety, you may be able to join.
Lahore, Punjab ProvinceAges 18–65 - NCT06652503Recruiting
Student wellness and emotional growth program
This trial tests a program called SWAG-R designed to help NSU undergraduate students build resilience and manage emotions. It may be a good fit if you are not currently in therapy or dealing with serious mental health issues.
Fort Lauderdale, FloridaAges 18 years+ - NCT06685094Recruiting
Pain, movement, and quality of life study for Albanian speakers
This study is translating health questionnaires into Albanian to better understand pain, movement, mood, and quality of life. It aims to help people with muscle, joint, or back pain.
Murcia, MurciaAges 18–80 - NCT06705153Recruiting
Laughter yoga for irritable bowel syndrome
This study tests whether laughter yoga can help reduce IBS symptoms like belly pain and bloating, and also improve mood, sleep, and overall quality of life. You would join video calls where you practice special laughing exercises (no jokes needed) and then answer questionnaires.
Erzurum, YakutiyeAges 18–90 - NCT07685860Recruiting
PET scan study for depression with MAO-A
This study uses a special PET scan to look at MAO-A, a brain chemical linked to depression. It may help doctors better understand and diagnose depression.
Hefei, AnhuiAges 18–90 - NCT07682935Recruiting
Fishing therapy for schizophrenia: mood and quality of life
This study tests if fishing, as a supportive therapy, can help people with schizophrenia improve mood, reduce anxiety, and boost quality of life. It looks at changes in blood markers and well-being.
Elâzığ, CenterAges 18–60 - NCT07048574Recruiting
Mood and behavior in children with cystic fibrosis
This study looks at mood and behavior in children with cystic fibrosis (CF) under 12. By following children over time, researchers hope to better understand and help with depression, anxiety, and behavior challenges that may come up.
Orange, CaliforniaAges 1.5 years–11 years - NCT06722781Recruiting
Online group therapy for common mental health conditions
This trial tests an online group therapy for people waiting for high intensity CBT. It aims to provide quicker support for conditions like depression, anxiety, and PTSD.
Doncaster, South YorkshireAges 17 years+ - NCT06745349Recruiting
Online sleep course for adults in Saskatchewan
This study tests an online sleep course for adults who have trouble falling or staying asleep. It aims to help improve sleep without requiring in-person visits.
Regina, SaskatchewanAges 18 years+ - NCT06770075Recruiting
Brightline: testing a wellness app for college students
This study tests a smartphone app that may help students track and improve their mental well-being. Over 6 months, you will wear a device that monitors things like activity and sleep, and use a simple app to check in on your mood. It's designed for full-time undergraduates who do not have a current mental health condition and are not receiving mental health treatment.
SingaporeAges 18–25 - NCT06788977Recruiting
Migraine treatment in pregnancy with a nerve stimulation device
This trial tests if a device that gently stimulates a nerve on your forehead can safely treat migraines during pregnancy. You'll use the device at home and track your headaches via text or email.
Darien, ConnecticutAges 18–44 - NCT06789731Recruiting
Mindfulness program for first-generation college students in rural areas
This study tests whether mindfulness exercises can help first-generation college students stay in school and feel more supported. If you're a first-generation college student in a rural area, this online program might help you manage stress and stay on track.
Sioux Falls, South DakotaAges 18–64 - NCT06806176Recruiting
Study of CAT-GSH for returning patients
This trial is checking if a version of CBT-GSH (Cognitive Behavioral Therapy Guided Self-Help) works well for people who've had it before and are coming back for help with anxiety or depression. You'd get the same kind of low-intensity support again.
Ashton-under-LyneAges 16 years+ - NCT06812247Recruiting
Therapy dog visits for hospitalized trauma patients
This study looks at whether visits from therapy dogs can help people who are in the hospital after a traumatic injury feel better. You must be able to talk to the research team and not be afraid of dogs.
Boston, MassachusettsAges 18 years+ - NCT06827951Recruiting
Parent-child therapy for young kids with behavior issues
This study tests if a therapy called Parent-Child Interaction Therapy (PCIT) helps parents of young children with behavioral concerns. You and your child would attend sessions together to improve your relationship and manage behaviors.
Gainesville, FloridaAges 18–89 - NCT06839859RecruitingPhase 2
Family Acceptance Project online pilot study
This trial tests an online program called Family Acceptance Project to help LGBTQ+ youth of color and their families improve acceptance and reduce rejection. You and a caregiver will join separate online group sessions to learn communication and support skills.
Ann Arbor, MichiganAges 14 years+ - NCT06858189RecruitingPhase 2
Path to Wellness: therapy plus physical activity
This study combines talk therapy with a physical activity program to help treat depression or anxiety. It may help you feel better in both your mind and body.
Manhattan, KansasAges 18–65 - NCT06864156Recruiting
Molecules and vitamin levels in long COVID with brain fog
This study looks at certain molecules (called microRNAs) and vitamin B12 levels in people who have ongoing brain-related symptoms like depression, anxiety, or fatigue after a COVID-19 infection. It may help understand why some people have long-lasting symptoms and could lead to better treatments.
Mexico City, Mexico CityAges 18–65 - NCT06874790Recruiting
Web-based mental health app study for Latina women
This study tests a web-based app to help Latina women in Los Angeles or Orange County who are feeling anxious or depressed. If you are not currently in therapy or on medication, you may be able to join from home using your smartphone or computer.
Los Angeles, CaliforniaAges 18 years+ - NCT06901739Recruiting
Synbiotic for mental health in obesity
This trial tests if a synbiotic (a mix of probiotics and prebiotics) can improve mental health in people with obesity. It may help if you have obesity and also struggle with anxiety or depression.
Valencia, ValenciaAges 18–65
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Common questions
- Are there clinical trials for depression, anxiety?
- Yes. Clin2 currently lists 481 recruiting depression, anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression, anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression, anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.