Clinical trials
Depression in Adolescence clinical trials
Below are recruiting depression in adolescence clinical trials, each written for real people, not researchers. We’re tracking 79 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06853587Recruiting
Genetic test to help pick antidepressant for teens
This study tests whether using a cheek swab DNA test can help choose a better antidepressant for teenagers with anxiety or depression. The goal is to see if this personalized approach leads to fewer side effects and better results.
Calgary, AlbertaAges 12–17 - NCT06515236Enrolling by invitation
A study of depression treatment for teens from minority groups
This study is testing a new way to help teens (ages 12–18) from racial or ethnic minority groups who are feeling depressed. It looks at how working with a specially trained therapist can improve their mental health.
New Haven, ConnecticutAges 12 years+ - NCT07278752Enrolling by invitation
Social media and emotions in teens study
This study looks at how social media affects teenagers' emotions and daily experiences. Participants will use a smartphone app to track their feelings and social media use over time.
Dallas, TexasAges 13–18 - NCT06139861Recruiting
Better Sleep Study
This study tests a program to help you sleep better. It is for people who are generally healthy and do not have serious medical or mental health conditions.
Los Angeles, CaliforniaAges 12–18 - NCT07475845Recruiting
Yoga and therapy for teen depression
This study tests whether adding weekly yoga classes to a standard group therapy program helps teens feel better faster. It is for teenagers aged 12–18 who have mild to moderate depression and are safe to be physically active.
Boston, MassachusettsAges 12–18 - NCT07173205Recruiting
Coping toolkit for teens and young adults after cancer
This trial tests a mobile toolkit to help teens and young adults manage their emotions and cope better after finishing cancer treatment. It is designed for those who completed treatment 1 month to 5 years ago.
Greenville, North CarolinaAges 15–39 - NCT06963463Recruiting
Sleep & light therapy for teens with depression
This study tests a program that combines sleep and light therapy to help teens with depression and sleep problems feel better. It focuses on improving your sleep schedule and adding bright light exposure to boost mood.
Philadelphia, PennsylvaniaAges 12–18 - NCT06324864Recruiting
START NOW Adapted for migrant teens, ages 14-18
This trial tests a culturally adapted version of a program called START NOW. It's designed to help teenagers who are migrants in Switzerland and are feeling depressed or very stressed learn new skills to feel better.
Basel, Canton of Basel-CityAges 14–18 - NCT06438276Recruiting
Mental health support for teens through school services
This study tests whether psychiatric outreach nurses can help teenagers aged 12-16 who are dealing with mood issues, anxiety, obsessive-compulsive or eating disorder symptoms, or mild self-harm. The goal is to see if this extra support improves their mental health compared to the usual school services.
Kuopio, Northern SavoniaAges 12–16 - NCT06941298Recruiting
Cannabis and depression study for teens and young adults
This study looks at how cannabis affects the brain and mood in teens and young adults. It compares people who use cannabis, people with depression who don't use cannabis, and healthy volunteers to understand links between cannabis use and mental health.
Miami, FloridaAges 14–20 - NCT07369752Recruiting
Breathing exercises for teens with depression or anxiety
This study looks at whether breathing exercises can help improve brain health and mental well-being in teens with depression or anxiety. It is designed for adolescents who are already receiving care at a Mayo Clinic psychiatry clinic.
Albert Lea, MinnesotaAges 12–17 - NCT07025720Recruiting
Brain stimulation for depression and suicide risk in young people
This study tests a new type of brain stimulation called TMS (transcranial magnetic stimulation) for young people ages 15-25 who are having serious depression and suicidal thoughts. The goal is to see if this treatment can help reduce risk and improve mood.
Sacramento, CaliforniaAges 15–25 - NCT05543083Recruiting
Therapy plus exercise for teens at risk of type 2 diabetes
This trial tests whether a combination of coaching (cognitive-behavioral therapy) and exercise can improve mood and help teens who are at higher risk for type 2 diabetes. It may be especially helpful if you’re dealing with depression symptoms and a family history of type 2 diabetes.
Aurora, ColoradoAges 12–17 - NCT07117058Recruiting
Anxiety and depression screening for young cancer survivors
This study tests a quick tool to identify anxiety or depression in children, teens, and young adults who have finished intensive cancer treatment and are now in remission. It aims to help doctors provide better mental health support.
CaenAges 7–25 - NCT06733883Recruiting
Music therapy for teens with emotional difficulties
This trial tests if music therapy can help adolescents aged 13 to 18 who are struggling with emotional challenges. If you join, you may attend music therapy sessions that could improve how you feel.
Oslo, NydalenAges 13–18 - NCT07020572Recruiting
Teen mood support program (iMATTER) in primary care
This study tests a group program to help teenagers with mild to moderate depression symptoms feel better. It takes place in primary care and uses a phone, computer, or tablet for activities.
Philadelphia, PennsylvaniaAges 13–17 - NCT07637799Recruiting
Parent support group for teens with autism and anxiety or depression
This study tests whether a parent support group helps families manage anxiety or depression in teenagers who have autism. The group teaches parents skills to support their teen at home.
GothenburgAges 12 years+ - NCT07007247Enrolling by invitation
Digital aftercare for teens with depression after hospital discharge
This pilot study tests a digital program to support adolescents aged 12–17 with depression after they leave the hospital. It aims to help prevent relapse and improve well-being using a smartphone, tablet, or computer.
HamburgAges 12–17 - NCT07129070Recruiting
Just-in-Time Training for Youth Mentors
This trial tests a new training program for mentors working with middle and high school students. It aims to help mentors better support youth who may be experiencing depression.
Minneapolis, MinnesotaAges 12 years+ - NCT06273137Recruiting
Positive affect treatment for teens with early adversity
This trial tests a treatment designed to improve positive emotions in adolescents who have experienced stressful early life events. It may help your teen build resilience and emotional wellbeing.
Irvine, CaliforniaAges 12–16 - NCT06248203Recruiting
Teacher-led mental health support for teens in Darjeeling
This trial tests a program in which teachers get extra training to support students with emotional or behavioral challenges in low-cost private schools in Darjeeling. It aims to see if teachers can make a positive difference for these teens.
Darjeeling, West BengalAges 13 years+ - NCT06390462Recruiting
Counseling for teens in school-based primary care
This study tests a brief counseling approach called Interpersonal Counseling for Adolescents (IPC-A) in school settings. It aims to help teens with emotional or social challenges before they become more serious, and it's designed for those who aren't already in mental health treatment.
HämeenlinnaAges 13–16 - NCT04245436RecruitingPhase 4
Testing antidepressants for teens with anxiety
This trial studies whether an antidepressant can help teens (ages 12–17) with anxiety disorders such as generalized, social, separation, or panic anxiety. It looks at both early and longer-term success of treatment, while monitoring safety closely with a caregiver.
Cincinnati, OhioAges 12–17 - NCT06236919Recruiting
Virtual reality for emotional regulation in kids and teens
This study tests a virtual reality program designed to help children and teens learn to manage their emotions. It's offered in schools and aims to improve emotional regulation skills.
BarcelonaAges 10–16
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Common questions
- Are there clinical trials for depression in adolescence?
- Yes. Clin2 currently lists 79 recruiting depression in adolescence studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression in adolescence trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression in adolescence trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.