Clinical trials
Depressive and Anxiety Disorders clinical trials
Below are recruiting depressive and anxiety disorders clinical trials, each written for real people, not researchers. We’re tracking 454 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05648539Recruiting
Music therapy for mood and anxiety symptoms
This trial studies whether music therapy can improve symptoms of depression or anxiety. You may be invited if you have mild mood or anxiety symptoms on common screening questionnaires.
Nanjing, JiangsuAges 16–35 - NCT05779761Recruiting
Brief coping exercises for high distress and worry
This study tests brief coping interventions to help people who feel very worried, stuck in negative thoughts, or overly self-critical. You would likely complete short activities using your smartphone and internet while the study checks how your distress changes over time.
New York, New YorkAges 18–65 - NCT05789446Recruiting
Testing a coping and identity skills program for teens
This study tests whether a skills program helps children better cope and build a strong sense of identity. It is offered to early teens and may help with stress and emotional challenges.
Harrisburg, PennsylvaniaAges 11 years+ - NCT05810259Recruiting
Digital wellness modules to improve quality of life
This study tests whether online “wellness” lessons help people feel better in everyday life and report a higher quality of life. It likely involves completing digital wellness modules and answering questionnaires to measure changes over time.
New Haven, ConnecticutAges 18–65 - NCT05845541Recruiting
Meditation and body feedback for mood after stroke
This study tests whether guided meditation and biofeedback can improve anxiety, depression, and quality of life for people recovering in inpatient rehab after a recent stroke. It may help you feel better emotionally and cope more easily during recovery.
Toronto, OntarioAges 18 years+ - NCT05883540RecruitingPhase 2
LSD therapy in palliative care for comfort and well-being
This Phase 2 study tests how LSD may affect comfort and quality of life for people with advanced or end-stage life-limiting illness. It also checks whether the medicine is safe and can be given in a controlled way in palliative care settings.
BaselAges 22 years+ - NCT05908565Recruiting
Digital therapy program for Latinx college students in East LA
This study tests a digital (online) prevention and therapy program called STAND to see if it improves engagement and outcomes. You may be able to participate if you’re a Latinx student at East Los Angeles College and can complete online assessments.
Los Angeles, CaliforniaAges 18–40 - NCT06046586Recruiting
Online therapy for cancer survivors with anxiety or depression
This trial tests an online therapy program for cancer survivors who feel anxious, depressed, or worried about cancer coming back. It's a text-based program you can do from home.
StockholmAges 18 years+ - NCT06121284RecruitingPhase 2
Brain stimulation plus medication for youth suicide
This study tests if a new type of brain stimulation (iTBS) combined with a medicine called D-cycloserine can reduce suicidal thoughts in young adults who have previously attempted suicide. It aims to find a faster, mood-boosting treatment option for young people at risk.
Calgary, AlbertaAges 18–24 - NCT06163599Recruiting
Telenovela for anxiety in Latinx adults
This trial tests if a telenovela-style video can help reduce anxiety symptoms in Spanish-speaking Latinx adults. You may be eligible if you have mild to moderate anxiety and want to participate from home using your smartphone.
Reno, NevadaAges 18 years+ - NCT06200155RecruitingPhase 2
Psilocybin therapy for advanced cancer patients with anxiety or depression
This trial tests whether a drug called psilocybin, given with therapy, can help people with advanced cancer who are feeling anxious or depressed. You must have a stable cancer and be willing to travel to Houston for treatment.
Houston, TexasAges 25 years+ - NCT06226155Recruiting
HIV prevention support for pregnant women in Zimbabwe
This study in Zimbabwe tests a program to help pregnant women start and stay on PrEP (medication that prevents HIV). It aims to make PrEP easier to use during pregnancy for women who are at risk of HIV.
HarareAges 15–55 - NCT06236919Recruiting
Virtual reality for emotional regulation in kids and teens
This study tests a virtual reality program designed to help children and teens learn to manage their emotions. It's offered in schools and aims to improve emotional regulation skills.
BarcelonaAges 10–16 - NCT06243614RecruitingPhase 3
Testing buagafuran capsules for generalized anxiety disorder
This trial tests a new medication called buagafuran for people with generalized anxiety disorder (GAD). It aims to see if the drug can safely reduce anxiety symptoms.
Beijing, Beijing MunicipalityAges 18–65 - NCT06243640RecruitingPhase 3
New capsule for generalized anxiety disorder trial
This trial tests a new capsule called Buagafuran for adults with generalized anxiety disorder (GAD). It aims to see if the medication helps reduce anxiety without causing major side effects.
Beijing, Beijing MunicipalityAges 18–65 - NCT06261463Recruiting
Peer-led support group for refugee families in Chicago
This study is testing a support program led by trained peers to help refugee families strengthen family bonds and cope with challenges. It is designed for Arabic-speaking families who have recently settled in Chicago.
Chicago, IllinoisAges 12–55 - NCT06266611RecruitingPhase 2
Cannabis for cancer symptom relief
This trial tests whether cannabis can help cancer patients manage symptoms like sleep trouble, pain, and mood changes. It's for people who are new to using cannabis for these issues.
Aurora, ColoradoAges 25 years+ - NCT06374277Recruiting
Pharmacy Coaching to Help After Hospital Stay
This study tests a program where a pharmacist helps you manage your medications after you leave the hospital. It is for people with long-term health conditions who want to stay on track with their medicines.
Knoxville, TennesseeAges 18 years+ - NCT06438276Recruiting
Mental health support for teens through school services
This study tests whether psychiatric outreach nurses can help teenagers aged 12-16 who are dealing with mood issues, anxiety, obsessive-compulsive or eating disorder symptoms, or mild self-harm. The goal is to see if this extra support improves their mental health compared to the usual school services.
Kuopio, Northern SavoniaAges 12–16 - NCT06514495Recruiting
Virtual vs. real-life therapy for agoraphobia
This study compares facing fears in virtual reality versus real-life situations for people with agoraphobia. Researchers want to see which method works better to reduce anxiety.
MainzAges 18–75 - NCT06546917Recruiting
Cognitive training trial for mild depression with brain scans
This trial tests a computer-based cognitive training program (bWell-D) to see if it can improve thinking skills like memory and focus in people with mild depression. You will also have an MRI brain scan to see how the training affects your brain.
Vancouver, British ColumbiaAges 19–55 - NCT06557005Recruiting
Helping new mothers with chronic conditions get primary care
This study helps new mothers with chronic health conditions transition smoothly from pregnancy care to regular primary care. If you have high blood pressure, diabetes, severe obesity, depression, or anxiety, you may be able to join a program that coordinates your care after childbirth.
Boston, MassachusettsAges 18 years+ - NCT06568419Recruiting
Online therapy for mental health and work
This trial tests an online program to help people on sick leave due to anxiety or depression return to work. You would receive therapy through a secure website while staying with your regular mental health care team.
Oslo, BærumAges 18–65 - NCT06591663Recruiting
Does a therapy rating tool work across cultures?
This study tests whether a therapy rating scale, usually used in Western settings, works well in Pakistan. It aims to make the tool more relevant for local patients and therapists.
Lahore, Punjab ProvinceAges 18–65
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Common questions
- Are there clinical trials for depressive and anxiety disorders?
- Yes. Clin2 currently lists 454 recruiting depressive and anxiety disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depressive and anxiety disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depressive and anxiety disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.