Clinical trials
Depressive and Anxiety Disorders clinical trials
Below are recruiting depressive and anxiety disorders clinical trials, each written for real people, not researchers. We’re tracking 435 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06430853Enrolling by invitation
Pregnancy support study for moms with anxiety or depression
This study tests if a mental health program during pregnancy can help mothers with past or current anxiety or depression. You'll get support and you may feel better and have a healthier pregnancy.
Stanford, CaliforniaAges 18 years+ - NCT06399991Recruiting
Improving mental health care in Malawi clinics
This study is testing a new way to help clinics in Malawi better support patients with mental health needs. If you are an adult patient at a participating clinic who has recently had symptoms of depression or anxiety, you may be eligible.
ChiradzuluAges 18 years+ - NCT06374277Recruiting
Pharmacy Coaching to Help After Hospital Stay
This study tests a program where a pharmacist helps you manage your medications after you leave the hospital. It is for people with long-term health conditions who want to stay on track with their medicines.
Knoxville, TennesseeAges 18 years+ - NCT06261463Recruiting
Peer-led support group for refugee families in Chicago
This study is testing a support program led by trained peers to help refugee families strengthen family bonds and cope with challenges. It is designed for Arabic-speaking families who have recently settled in Chicago.
Chicago, IllinoisAges 12–55 - NCT06236919Recruiting
Virtual reality for emotional regulation in kids and teens
This study tests a virtual reality program designed to help children and teens learn to manage their emotions. It's offered in schools and aims to improve emotional regulation skills.
BarcelonaAges 10–16 - NCT06226155Recruiting
HIV prevention support for pregnant women in Zimbabwe
This study in Zimbabwe tests a program to help pregnant women start and stay on PrEP (medication that prevents HIV). It aims to make PrEP easier to use during pregnancy for women who are at risk of HIV.
HarareAges 15–55 - NCT06200155RecruitingPhase 2
Psilocybin therapy for advanced cancer patients with anxiety or depression
This trial tests whether a drug called psilocybin, given with therapy, can help people with advanced cancer who are feeling anxious or depressed. You must have a stable cancer and be willing to travel to Houston for treatment.
Houston, TexasAges 25 years+ - NCT06046586Recruiting
Online therapy for cancer survivors with anxiety or depression
This trial tests an online therapy program for cancer survivors who feel anxious, depressed, or worried about cancer coming back. It's a text-based program you can do from home.
StockholmAges 18 years+ - NCT05883540RecruitingPhase 2
LSD therapy in palliative care for comfort and well-being
This Phase 2 study tests how LSD may affect comfort and quality of life for people with advanced or end-stage life-limiting illness. It also checks whether the medicine is safe and can be given in a controlled way in palliative care settings.
BaselAges 22 years+ - NCT05810259Recruiting
Digital wellness modules to improve quality of life
This study tests whether online “wellness” lessons help people feel better in everyday life and report a higher quality of life. It likely involves completing digital wellness modules and answering questionnaires to measure changes over time.
New Haven, ConnecticutAges 18–65 - NCT05789446Recruiting
Testing a coping and identity skills program for teens
This study tests whether a skills program helps children better cope and build a strong sense of identity. It is offered to early teens and may help with stress and emotional challenges.
Harrisburg, PennsylvaniaAges 11 years+ - NCT05746767Enrolling by invitation
Spanish digital therapy coaching for depression and anxiety
This study tests a digital “cognitive behavioral therapy” program with peer support to help Spanish-speaking adults with depression or anxiety. It may help you manage symptoms using structured online tools and guided peer interaction.
Payson, ArizonaAges 18 years+ - NCT05603000Recruiting
Emotion-focused therapy for parents of anxious or struggling children
This study tests an emotion-focused family therapy program for parents of children (ages 7–15) who are dealing with anxiety, depression, or behavior challenges. It may help families improve how emotions are understood and managed through parent participation and home life support.
Guelph, OntarioAges 7–15 - NCT05591937Recruiting
Online therapy and prevention support for eligible East LA students
This project offers online mental health prevention and therapy programs and short assessments for eligible students. It may help you access support in a convenient way if you meet the study’s student, coverage, and technology needs.
Los Angeles, CaliforniaAges 18–40 - NCT05461092RecruitingEarly Phase 1
Nerve blocks to improve pain control after spinal fusion
This early-stage study tests whether a regional nerve block can improve pain control and recovery for older adults having elective lumbar spinal fusion. If you qualify, you may receive a special pain-control injection during surgery to reduce opioid needs and improve recovery comfort.
Iowa City, IowaAges 65 years+ - NCT05434130RecruitingPhase 1/Phase 2
Testing the right exercise amount to help concussion recovery
This study tests whether adjusting how much exercise you do can improve recovery after a concussion. You may be screened to make sure symptoms are still present, and then assigned to an exercise plan that matches the study’s goals.
Aurora, ColoradoAges 13–18 - NCT05004987RecruitingPhase 4
Study brain and blood changes in older adults with depression
This study looks at how a brain protein linked to Alzheimer’s disease changes over time in older adults who have major depression but no major memory problems. It involves brain scans, blood and urine tests, and a spinal fluid sample to better understand the connection between depression and brain aging.
New York, New YorkAges 60 years+ - NCT04877977Recruiting
Long-Term Follow-Up for People With Mood Disorders
This study follows people with mood disorders over a long time to better understand how symptoms and functioning change. You may be able to join if you already agreed to take part in an earlier mood/anxiety study and you meet basic participation needs.
Bethesda, MarylandAges 18–99 - NCT05734768Recruiting
Study of anxiety and depression in parents after preterm birth
This study compares how parents feel (anxiety and depression symptoms) after having a baby born preterm versus a full-term baby. It also looks at early “building blocks” of thinking and social development in the child.
ReimsAges 18 years+ - NCT07878286Recruiting
How body awareness relates to fibromyalgia symptoms
This study looks at how well women with fibromyalgia notice internal body signals (like heartbeat or breathing) and whether that affects their pain and other symptoms. It may help doctors understand fibromyalgia better and improve future treatments.
IstanbulAges 18–65 - NCT05830266Recruiting
Mindfulness program to help mother–baby bonding in pregnancy and after
This study tests a mindfulness-based program to improve mother–baby bonding by supporting mood, anxiety, and stress during and after pregnancy. It may help if you’re currently having higher-than-average depression, anxiety, or stress symptoms.
Tilburg, North BrabantAges 18 years+ - NCT05800522Recruiting
Supportive parenting program for kids with behavior and mood struggles
This trial tests whether a supportive parenting program can help children who are showing higher-than-usual symptoms like anxiety, depression, anger, or behavior problems. If you’re not already in certain specialized mental health programs, your child may be able to join and get structured support for coping.
OsloAges 4–12 - NCT07717385Recruiting
90-day trial of a probiotic for stress and sleep
This study tests whether a daily probiotic capsule called Neuralli Mood can help adults who feel stressed, have trouble sleeping, or experience low mood. It lasts 90 days and involves taking two capsules each day and filling out online surveys.
New York, New YorkAges 18 years+ - NCT07606248Recruiting
Virtual forest mindfulness for pregnant women's mental health
This study tests whether using virtual reality to explore a calming digital forest helps reduce stress and improve mood during pregnancy. You'd use a VR headset a few times to practice mindfulness (focused breathing and relaxation) and complete short surveys about how you're feeling.
HsinchuAges 18 years+
Hear when a new Depressive and Anxiety Disorders trial opens
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Common questions
- Are there clinical trials for depressive and anxiety disorders?
- Yes. Clin2 currently lists 435 recruiting depressive and anxiety disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depressive and anxiety disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depressive and anxiety disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.