Clinical trials
Diabetes (Insulin-requiring, Type 1 or Type 2) clinical trials
Below are recruiting diabetes (insulin-requiring, type 1 or type 2) clinical trials, each written for real people, not researchers. We’re tracking 2,195 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06942520RecruitingPhase 2
Gene therapy for diabetic macular edema in adults
This trial tests a gene therapy called RGX-314 for people with diabetic macular edema that affects the center of the vision. If you have had previous treatment and still have swelling, this study may be an option.
Reno, NevadaAges 25–89 - NCT06052254RecruitingPhase 2
Skin patch for agitation in Alzheimer's dementia
This trial tests a skin patch that delivers a medicine called dexmedetomidine to help calm agitation in people with Alzheimer's disease. It might be an option for those living in a care facility who have had recent episodes of agitation.
Daytona Beach, FloridaAges Any age - NCT03746769RecruitingPhase 1/Phase 2
Testing gastrin to improve results of islet cell transplant
This trial looks at whether adding gastrin can improve outcomes after an islet cell transplant for people with type 1 diabetes. It may help some participants achieve better blood sugar control, but it also requires close follow-up and immune-suppressing medications to protect the new cells.
Duarte, CaliforniaAges 18–68 - NCT04670666RecruitingPhase 3
Study of Madalena for type 2 diabetes not controlled
This Phase 3 study tests Madalena to improve blood sugar control in adults with type 2 diabetes that hasn’t met targets despite diet, exercise, and diabetes medicines. You may join if your recent blood sugar tests and body size fall within specific ranges and you don’t have key medical exclusions.
Hortolândia, São PauloAges 18 years+ - NCT05279729Recruiting
Mobile app coaching for people with diabetes
This study tests whether using a smartphone app can help people with type 2 diabetes manage their health. It focuses especially on low-income Hispanic/Latinx adults who regularly check blood sugar.
San Diego, CaliforniaAges 18–64 - NCT05630508Recruiting
Diabetes lifestyle app for Arabic-speaking adults
This trial tests a lifestyle coaching app on a phone to help adults with type 2 diabetes improve blood sugar. It may help if your diabetes is currently not well controlled.
Riyadh, Riyadh RegionAges 18 years+ - NCT05780905RecruitingPhase 4
Semaglutide study for brain blood flow in type 2 diabetes
This trial tests whether semaglutide changes blood flow in the brain and the brain’s “barrier” (how well the brain is protected) in people with type 2 diabetes. It may help researchers understand brain-related effects of diabetes treatment using scans and blood tests.
Seattle, WashingtonAges 40–65 - NCT05887635Recruiting
RF treatment of the duodenum for type 2 diabetes control
This trial tests whether a procedure that uses heat energy (radiofrequency vapor ablation) applied in the first part of the small intestine (duodenum) can improve blood sugar control in adults with type 2 diabetes. It may help lower blood sugar when standard oral medicines are not keeping it in range.
SantiagoAges 18–65 - NCT06329882RecruitingPhase 1/Phase 2
Doxycycline for newly diagnosed type 2 diabetes
This trial tests whether the antibiotic doxycycline can help control blood sugar in people newly diagnosed with type 2 diabetes. If you are over 40 and have not taken diabetes medications yet, you may be able to join.
TantaAges 40–60 - NCT06478186RecruitingPhase 4
Knee Osteoarthritis Steroid Injection Study for People with Type 2 Diabetes
This study compares two different steroid knee injections—Zilretta and Kenalog—to see which works better for people with both knee osteoarthritis and type 2 diabetes. It uses a continuous glucose monitor to track blood sugar changes.
Kansas City, KansasAges 40 years+ - NCT06516640Recruiting
CGM Education for Type 2 Diabetes
This trial helps teens and young adults with type 2 diabetes learn to use continuous glucose monitors (CGMs). It aims to make managing diabetes easier and more effective.
Los Angeles, CaliforniaAges 8–21 - NCT06541847RecruitingPhase 2
Testing HLX-1502 for NF1 with Plexiform Neurofibromas
This trial tests an experimental drug called HLX-1502 for people with NF1 who have a plexiform neurofibroma (a type of nerve tumor) that is growing or causing problems. It aims to see if the drug is safe and can shrink or stop the tumor from worsening.
Birmingham, AlabamaAges 12 years+ - NCT06547970Recruiting
Pharmacist education for type 1 diabetes: quality of life and adherence
This study tests whether a pharmacist-led education program can improve quality of life, medication adherence, and satisfaction for people with type 1 diabetes whose blood sugar is not well controlled. It is designed for Arabic-speaking adults and teens 16 and older.
BaghdadAges 16 years+ - NCT06647888Recruiting
Study of Enavogliflozin for Type 2 Diabetes with High Blood Pressure or High Cholesterol
This study looks at how well a medication called Enavogliflozin works for people with type 2 diabetes who also have high blood pressure or high cholesterol. It aims to see if the drug is safe and effective when taken as part of routine care.
SeoulAges 19 years+ - NCT06729242Recruiting
How menstrual cycle phases affect exercise and blood sugar in type 1 diabetes
This study looks at how the menstrual cycle changes the way your body responds to aerobic exercise or high-intensity interval training (HIIT) when you have type 1 diabetes. It may help you understand the best time to exercise for better blood sugar control.
Valencia, Select OneAges 18–45 - NCT06849622Recruiting
Blood spot test for type 1 diabetes and celiac disease
This study tests a new way to check for type 1 diabetes and celiac disease using a tiny drop of blood from a finger prick, instead of a regular blood draw. The goal is to make diagnosis easier and less scary for children.
Florence, ItalyAges 2–13 - NCT06860516Recruiting
HLA Demographics Study in Adults With Type 1 Diabetes
This study (NCT06860516) is an observational trial of adults aged 18-55 with type 1 diabetes diagnosed within 6 months. It aims to collect demographic and HLA data.
San Francisco, CaliforniaAges 18–55 - NCT06895980Recruiting
Gum treatment for better blood sugar in diabetes
This trial tests whether treating gum disease can help improve blood sugar control in people with type 2 diabetes. If you have poorly controlled diabetes and gum disease, you may be able to join this study.
Santiago, ProvidenciaAges 18 years+ - NCT06904690Recruiting
Health literacy training for older adults with type 2 diabetes
This trial tests whether an online training program can help older adults with type 2 diabetes better understand and use health information. It may improve your ability to manage your diabetes.
AnconaAges 60 years+ - NCT06964087RecruitingPhase 2
Testing OPT101 for type 1 diabetes
This trial tests an investigational drug called OPT101 in people with type 1 diabetes. It aims to see how the drug works in the body and whether it can help preserve insulin production, especially in those diagnosed recently or within the last 20 years.
Birmingham, AlabamaAges 18–50 - NCT07006233Recruiting
Dietary change study for narcolepsy and hypersomnia
This study tests whether changing your diet to include more animal protein and fat (like a low-carb diet) can improve symptoms of narcolepsy or idiopathic hypersomnia. You'll need to check your ketone levels at home and be willing to make lasting dietary changes.
Macquarie Park, New South WalesAges 18 years+ - NCT07355270Recruiting
Radiofrequency vapor ablation for type 2 diabetes
This trial tests a new device that uses radiofrequency energy to treat the lining of the upper small intestine in people with type 2 diabetes. The goal is to see if this treatment is safe and helps improve blood sugar control.
Scottsdale, ArizonaAges 22–65 - NCT07359105Recruiting
Statin vs. LDL Goal Therapy for Older Adults with Diabetes
This trial compares two approaches to lower cholesterol in people aged 70+ with type 2 diabetes: a moderate statin dose versus adjusting treatment to reach a personalized LDL-C target. It aims to find which strategy better prevents heart problems.
SeoulAges 70 years+ - NCT07469943Recruiting
Diabetes drug after heart attack
This study tests whether a diabetes medication can improve artery health and heart function after a heart attack. It is for people who have had a STEMI and also have diabetes or a weakened heart pump.
Athens, Rimini1/HaidariAges 18–80
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Common questions
- Are there clinical trials for diabetes (insulin-requiring, type 1 or type 2)?
- Yes. Clin2 currently lists 2,195 recruiting diabetes (insulin-requiring, type 1 or type 2) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetes (insulin-requiring, type 1 or type 2) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetes (insulin-requiring, type 1 or type 2) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.