Clinical trials
Diabetes (Insulin-requiring, Type 1 or Type 2) clinical trials
Below are recruiting diabetes (insulin-requiring, type 1 or type 2) clinical trials, each written for real people, not researchers. We’re tracking 2,155 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06942520RecruitingPhase 2
Gene therapy for diabetic macular edema in adults
This trial tests a gene therapy called RGX-314 for people with diabetic macular edema that affects the center of the vision. If you have had previous treatment and still have swelling, this study may be an option.
Reno, NevadaAges 25–89 - NCT07006233Recruiting
Dietary change study for narcolepsy and hypersomnia
This study tests whether changing your diet to include more animal protein and fat (like a low-carb diet) can improve symptoms of narcolepsy or idiopathic hypersomnia. You'll need to check your ketone levels at home and be willing to make lasting dietary changes.
Macquarie Park, New South WalesAges 18 years+ - NCT06964087RecruitingPhase 2
Testing OPT101 for type 1 diabetes
This trial tests an investigational drug called OPT101 in people with type 1 diabetes. It aims to see how the drug works in the body and whether it can help preserve insulin production, especially in those diagnosed recently or within the last 20 years.
Birmingham, AlabamaAges 18–50 - NCT05630508Recruiting
Diabetes lifestyle app for Arabic-speaking adults
This trial tests a lifestyle coaching app on a phone to help adults with type 2 diabetes improve blood sugar. It may help if your diabetes is currently not well controlled.
Riyadh, Riyadh RegionAges 18 years+ - NCT06860516Recruiting
HLA Demographics Study in Adults With Type 1 Diabetes
This study (NCT06860516) is an observational trial of adults aged 18-55 with type 1 diabetes diagnosed within 6 months. It aims to collect demographic and HLA data.
San Francisco, CaliforniaAges 18–55 - NCT06729242Recruiting
How menstrual cycle phases affect exercise and blood sugar in type 1 diabetes
This study looks at how the menstrual cycle changes the way your body responds to aerobic exercise or high-intensity interval training (HIIT) when you have type 1 diabetes. It may help you understand the best time to exercise for better blood sugar control.
Valencia, Select OneAges 18–45 - NCT06541847RecruitingPhase 2
Testing HLX-1502 for NF1 with Plexiform Neurofibromas
This trial tests an experimental drug called HLX-1502 for people with NF1 who have a plexiform neurofibroma (a type of nerve tumor) that is growing or causing problems. It aims to see if the drug is safe and can shrink or stop the tumor from worsening.
Birmingham, AlabamaAges 12 years+ - NCT06516640Recruiting
CGM Education for Type 2 Diabetes
This trial helps teens and young adults with type 2 diabetes learn to use continuous glucose monitors (CGMs). It aims to make managing diabetes easier and more effective.
Los Angeles, CaliforniaAges 8–21 - NCT06478186RecruitingPhase 4
Knee Osteoarthritis Steroid Injection Study for People with Type 2 Diabetes
This study compares two different steroid knee injections—Zilretta and Kenalog—to see which works better for people with both knee osteoarthritis and type 2 diabetes. It uses a continuous glucose monitor to track blood sugar changes.
Kansas City, KansasAges 40 years+ - NCT06052254RecruitingPhase 2
Skin patch for agitation in Alzheimer's dementia
This trial tests a skin patch that delivers a medicine called dexmedetomidine to help calm agitation in people with Alzheimer's disease. It might be an option for those living in a care facility who have had recent episodes of agitation.
Chino, CaliforniaAges Any age - NCT05838287RecruitingPhase 4
Pioglitazone for heart failure with preserved pumping in type 2 diabetes
This trial tests whether pioglitazone (a diabetes medicine) helps people who have type 2 diabetes and a specific type of heart failure where the heart pumps normally. It may improve heart failure symptoms and function in carefully selected patients.
San Antonio, TexasAges 30–70 - NCT04670666RecruitingPhase 3
Study of Madalena for type 2 diabetes not controlled
This Phase 3 study tests Madalena to improve blood sugar control in adults with type 2 diabetes that hasn’t met targets despite diet, exercise, and diabetes medicines. You may join if your recent blood sugar tests and body size fall within specific ranges and you don’t have key medical exclusions.
Hortolândia, São PauloAges 18 years+ - NCT05279729Recruiting
Mobile app coaching for people with diabetes
This study tests whether using a smartphone app can help people with type 2 diabetes manage their health. It focuses especially on low-income Hispanic/Latinx adults who regularly check blood sugar.
San Diego, CaliforniaAges 18–64 - NCT06674980Recruiting
Testing placenta-based wound treatment for diabetic and venous leg ulcers
This trial tests if adding a special placenta-based wound covering to standard care helps heal diabetic foot ulcers and venous leg ulcers faster. It's for people with wounds that haven't healed after standard treatment for at least 4 weeks.
Metairie, LouisianaAges 18 years+ - NCT06914778Recruiting
How diabetes affects the eyes in South Wales
This study looks at how fat and sugar levels in the blood relate to different stages of eye damage in people with type 2 diabetes. It may help find new ways to treat or prevent vision loss.
Llanelli, WalesAges 18–80 - NCT07036796RecruitingPhase 2
Melatonin for diabetic nerve pain
This trial tests whether melatonin can help relieve pain and discomfort from diabetic peripheral neuropathy (nerve damage caused by diabetes). If you have type 2 diabetes with nerve pain and are on stable diabetes medications, you may be eligible.
CairoAges 40–75 - NCT03307486Enrolling by invitation
Study of gestational diabetes during pregnancy
This study follows pregnant people to understand gestational diabetes (high blood sugar during pregnancy) and how it shows up and is monitored. It may help improve future screening and care for gestational diabetes.
São PauloAges Any age - NCT07877948Recruiting
Combination therapy for diabetic nerve pain and foot ulcers
This study tests whether a treatment called Bionerv E+ helps with nerve pain and healing of foot ulcers in people with type 2 diabetes, compared with a standard vitamin B complex. If you have diabetes-related nerve damage and a foot ulcer that is not too severe, this study might help you understand if this new option works.
Cheras, Kuala LumpurAges 18 years+ - NCT05883072Recruiting
Using AI to support care for people with diabetes in Pakistan
This study tests whether AI-generated support can be helpful for adults living with diabetes. You may be asked to participate if you live in Pakistan and can legally consent.
Karachi, SindhAges 18–100 - NCT06264427Recruiting
Study of metabolism issues in Greenland
This study looks at the genes and physical traits of people in Greenland with type 2 diabetes or severe obesity. It aims to better understand these conditions to improve care.
Nuuk, SermersooqAges 18 years+ - NCT06461377RecruitingPhase 4
GLP-1RA for heart nerve damage in type 2 diabetes
This trial tests whether a type of diabetes medicine called GLP-1RA can help prevent or improve nerve damage in the heart caused by diabetes. It is for people with type 2 diabetes who are overweight or obese.
Nanjing, JiangsuAges 18–70 - NCT05008276Recruiting
Study of puberty, diabetes, and kidney stress in teens
This trial studies how puberty and blood sugar changes affect the kidneys in people with type 1 diabetes. It may help researchers understand early kidney risk and identify who needs closer monitoring.
Aurora, ColoradoAges 8–14 - NCT07091487Recruiting
Diabetes Homeless Medication Support Program
This study tests a program that helps people who have both type 2 diabetes and housing instability. The program supports you in taking your medication and managing your diabetes day-to-day.
Minneapolis, MinnesotaAges 18 years+ - NCT06713720Recruiting
Arm Cuff Therapy for Early Diabetic Eye Disease
This study tests if a simple, non-invasive treatment called remote ischemic conditioning (briefly restricting blood flow to one arm using a special cuff) can help slow down early-stage diabetic eye disease in people with type 2 diabetes. You join the study to potentially prevent your retinopathy from getting worse.
Beijing, Beijing MunicipalityAges 40–80
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Common questions
- Are there clinical trials for diabetes (insulin-requiring, type 1 or type 2)?
- Yes. Clin2 currently lists 2,155 recruiting diabetes (insulin-requiring, type 1 or type 2) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetes (insulin-requiring, type 1 or type 2) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetes (insulin-requiring, type 1 or type 2) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.