Diabetes Mellitus in Pregnancy clinical trials

Study of puberty, diabetes, and kidney stress in teens

This trial studies how puberty and blood sugar changes affect the kidneys in people with type 1 diabetes. It may help researchers understand early kidney risk and identify who needs closer monitoring.

Oral treatment test for type 2 diabetes and bad cholesterol

This Phase 3 study tests whether Berlim 25/20 can improve blood sugar control and cholesterol (LDL) in adults with type 2 diabetes who haven’t met targets despite prior lifestyle guidance and treatment. It also looks at safety, including effects on the heart and medication-related side effects.

Alpha lipoic acid and vitamin B for diabetic nerve damage

This trial tests whether a combination of alpha lipoic acid (a natural antioxidant) and vitamin B supplements can help relieve nerve pain, numbness, or tingling caused by diabetes. It is for people with type 2 diabetes who have diabetic nerve damage.

MSC therapy for type 2 diabetes

This trial tests whether a type of stem cell treatment (called cfMSC) can help people with long-standing type 2 diabetes who are not getting good blood sugar control from their current treatments. The therapy aims to improve blood sugar levels and may help preserve the body's ability to produce insulin.

Reducing high insulin levels in type 1 diabetes

This study tests if adding a non-insulin medication can lower the amount of insulin needed while improving heart and metabolic health in people with type 1 diabetes. It may also help understand how this approach works in people with a genetic form of diabetes (GCK-MODY).

Reproductive Health Study for Pregnant Women in Somaliland

This study explores reproductive health in women living in Somaliland who are in early to mid-pregnancy. The goal is to learn more about health needs and experiences during pregnancy.

Remission of type 2 diabetes with lifestyle changes

This trial tests whether a lifestyle program can help people recently diagnosed with type 2 diabetes achieve remission. It focuses on diet and physical activity, not medications.

Wait or induce at 38 weeks for gestational diabetes

This trial compares two approaches for people with gestational diabetes: waiting for labor to start naturally versus inducing labor at 38 weeks. The goal is to see if one plan leads to better outcomes for both mother and baby.

Testing Chiglitazar for fatty liver with diabetes

This trial tests a new oral medication, Chiglitazar, for people who have both type 2 diabetes and a fatty liver condition called MASH (fatty liver with inflammation and scarring). It aims to see if the drug can help improve liver health and diabetes control.

Capsule transplant for newly diagnosed type 1 diabetes

This study tests if taking capsules with processed donor stool can help preserve insulin-making cells in people recently diagnosed with type 1 diabetes. The treatment aims to slow the loss of insulin production.

MRI and brain testing in teens at risk for type 2 diabetes

This study looks at brain health in teens with normal weight, overweight, or obesity who are at risk for type 2 diabetes. It may help researchers understand how weight and diabetes risk affect the brain, using MRI scans and learning/memory tests.

Diabetes Treatment in Liver Transplant Patients and Candidates

This study looks at people with type 2 diabetes who are either waiting for a liver transplant or have already had one. Researchers want to understand how diabetes treatment affects outcomes before and after transplant.

Testing a diabetes pill under the tongue for type 2 diabetes

This early-phase study tests the safety and side effects of liraglutide taken under the tongue, and looks for early signs it improves blood sugar in people with type 2 diabetes. It may help people who want an alternative way to get this medication, but the main goal is to see how safe and tolerable it is.

Safety trial of ExOlin® for adults with hard-to-control type 1 diabetes

This trial checks whether ExOlin® is safe in adults with type 1 diabetes who have had difficult blood sugar control or injection-site skin problems despite insulin pump and continuous glucose monitoring. It’s mainly looking for safety and comfort while using the treatment devices.

Study on continuous glucose monitors for type 2 diabetes

This study gives continuous glucose monitors (CGMs) to people with type 2 diabetes who cannot afford them. It looks at whether using a CGM helps improve blood sugar control.

Natural cervical ripening to avoid labor induction

This study tests whether natural methods can help your cervix prepare for labor on its own, so you may avoid medication-induced labor. It's designed for pregnant people with diet-controlled gestational diabetes who are planning a vaginal delivery at 40 weeks.

Weekly semaglutide with closed-loop system for type 1 diabetes

This trial tests whether adding a weekly semaglutide injection (a GLP-1 drug) to a closed-loop insulin system can help reduce the need for carb counting in people with type 1 diabetes. It aims to improve blood sugar control and make diabetes management easier.

Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes

Probiotics plus diabetes medicine for pregnancy blood sugar

This study tests whether adding probiotics (beneficial bacteria) to standard diabetes medication helps manage high blood sugar during pregnancy. Researchers hope this combination may improve health outcomes for both you and your baby.

Treatment for slightly high blood pressure in type 2 diabetes

This trial tests an intervention to help adults with type 2 diabetes who have “high-normal” blood pressure (not severely high). If you qualify, you may learn whether this approach improves blood pressure and related health outcomes over time.

Testing gastrin to improve results of islet cell transplant

This trial looks at whether adding gastrin can improve outcomes after an islet cell transplant for people with type 1 diabetes. It may help some participants achieve better blood sugar control, but it also requires close follow-up and immune-suppressing medications to protect the new cells.

Who may benefit from weight-loss surgery for diabetes?

This study looks at which people with type 2 diabetes (or prediabetes) are most likely to benefit from bariatric surgery. It compares people who are planning surgery with healthy volunteers to better understand how body changes relate to blood sugar.

Study genes and diabetes risk using body measurements

This study looks at how genetic risk relates to developing type 2 diabetes, using information from a biobank and body measurements like weight. It may help researchers better identify who is at higher risk before diabetes starts.

Study for early gestational diabetes in pregnancy

This study is looking at pregnant people who have early signs of gestational diabetes in the first half of pregnancy. It may help find safer ways to monitor or treat early diabetes-related blood sugar changes to improve pregnancy outcomes.