Clinical trials
Disability or Chronic Disease Leading to Disablement clinical trials
Below are recruiting disability or chronic disease leading to disablement clinical trials, each written for real people, not researchers. We’re tracking 688 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07707310Recruiting
Exercise to prevent disability after hospital stay
This study tests whether a gentle exercise program while you are in the hospital can help you stay strong and independent after you go home. It is for people aged 75 and older who are admitted for a medical condition.
PamplonaAges 75 years+ - NCT03492060Recruiting
Study of genetic variants in neurogenetic disorders over time
This study looks at how people’s genetic test results relate to health changes over time in conditions caused by gene differences. If you already have genetic confirmation of a disease-causing variant, you may be able to join.
New York, New YorkAges Any age - NCT03495440Recruiting
Family skills program for youth with developmental disabilities
This trial studies a parent-and-family intervention designed for families of youth with developmental disabilities. It may help parents and siblings better understand needs and improve day-to-day support at home through guided, theory-based activities and surveys.
Fort Wayne, IndianaAges Any age - NCT03696134Recruiting
Study of musculoskeletal health, frailty, pain, and disability
This study looks at musculoskeletal health and wellbeing in adults, especially people who are frail or at risk of developing frailty-related problems like pain or limited ability to move. It may help researchers understand what puts people at risk and what could improve comfort and function.
NottinghamAges 18 years+ - NCT03789552RecruitingPhase 3
Testing T89 to prevent chest pain during stable angina
This Phase 3 trial tests whether T89 reduces angina (chest pain caused by heart-related reduced blood flow) in people with stable angina. You may help confirm the treatment’s benefit by completing symptom tracking and exercise heart tests over several weeks.
Naples, FloridaAges 18–90 - NCT03852381Recruiting
Spinal cord stimulation for nerve pain after back surgery
This study looks at how spinal cord stimulation (a device that sends mild signals to the spinal cord) affects nerve pain after lumbar surgery. It also aims to help predict who is most likely to improve and why, comparing patients with and without certain sensory symptoms.
Toronto, OntarioAges 18–80 - NCT03910738RecruitingPhase 2
Testosterone treatment for nerve protection and myelin repair in MS
This Phase 2 study tests whether taking testosterone (for low testosterone levels) can help protect nerves and repair myelin in people with relapsing-remitting multiple sclerosis (MS). It may be most relevant if your MS is stable and you have low blood testosterone without current androgen treatment.
BesançonAges 18–55 - NCT03999723RecruitingPhase 2
Test azacitidine with vitamin C to improve DNA changes
This Phase 2 study tests whether combining azacitidine (a standard blood cancer medicine) with vitamin C helps improve disease control by changing DNA activity in high-risk blood cancers. It may be an option if you have certain types of higher-risk MDS, CMML, or low-blast AML and can meet safety requirements.
AalborgAges 18 years+ - NCT07701785Recruiting
Brain stimulation study for Parkinson's with mild memory issues
This trial tests a type of brain stimulation called iTBS on an area of the brain that may help with thinking and memory problems in people with Parkinson's disease and mild cognitive impairment. If you qualify, you and your caregiver would take part in sessions and answer questions about your daily life.
Charleston, South CarolinaAges 50–85 - NCT07588932RecruitingEarly Phase 1
Medication and Robot Training for Stroke Arm Recovery
This study tests whether three medications (Telmisartan, Cilostazol, and Metformin) combined with robotic arm training can help people improve arm movement and strength after a chronic stroke. You would participate in supervised training sessions using a robotic rehabilitation system.
Charlestown, MassachusettsAges 21–80 - NCT04026386Recruiting
Early intervention program for preschool children with developmental delays
This trial tests a structured, center-based early intervention program for preschoolers with developmental disorders. It may help children build skills and support development through guided activities and testing at the research site.
Stanford, CaliforniaAges 2–5 - NCT04071847Recruiting
Study tracking results after Abbott deep brain stimulator surgery
This study follows people who are getting a new Abbott deep brain stimulator (DBS) device or replacing the battery/implantable pulse generator to see how outcomes change over time. It mainly applies to certain DBS targets and diagnoses, and it uses follow-up visits to track results.
Tucson, ArizonaAges Any age - NCT04199299Recruiting
Communication sensors for people who can’t express needs clearly
This trial tests a wearable sensor system that may help people who have difficulty communicating their needs clearly. It may capture signals from the body so caregivers and devices can better understand reactions and needs.
OsloAges 5–80 - NCT04212780Recruiting
Testing a smarter DBS system for severe essential tremor
This trial tests an upgraded deep brain stimulation (DBS) system that can “sense” tremor and adjust treatment in a loop. It’s designed for people with severe essential tremor whose tremor is still disabling despite standard DBS and medication.
Gainesville, FloridaAges 21–99 - NCT04246437RecruitingPhase 1
Brain imaging study for autonomic failure with possible Parkinson disease
This Phase 1 study uses a special injected imaging tracer and an MRI scan to look at brain function in people with autonomic failure. It may help researchers understand what’s happening in conditions that can be related to Parkinson disease, multiple system atrophy, or dementia with Lewy bodies.
Nashville, TennesseeAges 18 years+ - NCT04256317RecruitingPhase 2/Phase 3
Azacitidine pills with or without venetoclax for certain blood cancers
This study tests whether a pill form of azacitidine (ASTX030) helps people with myelodysplastic syndromes (MDS), CMML, or AML. Some groups may also receive venetoclax; the goal is better blood cancer control for people who aren’t good candidates for intensive chemotherapy.
Los Angeles, CaliforniaAges 18 years+ - NCT04296097Recruiting
Deep brain stimulation for severe, steady disabling tinnitus
This study tests whether deep brain stimulation (a device that sends controlled signals to the brain) can reduce severe, constant tinnitus that has not improved with usual treatments. It may help lower the loudness distress and improve daily quality of life for people whose tinnitus is especially disabling.
GrenobleAges 18–75 - NCT04360200Recruiting
Study of thinking changes in older adults
This trial looks at people over age 50 who have mild thinking or memory problems but do not have dementia by standard clinical criteria. It tests how these early changes are characterized and measured using exams such as blood tests and brain scans, which may help improve understanding and future care.
Guangzhou, GuangdongAges 50 years+ - NCT04395495Recruiting
RASopathy disorder study biobank for kids and families
This study collects and stores health samples and information from people with RASopathy conditions (like Noonan or Costello syndromes) and from family members who may not have the condition. It helps researchers understand these disorders and supports future studies that could lead to better care.
Cincinnati, OhioAges Any age - NCT04433052Recruiting
Personalized heart-protection program for people at high risk
This trial tests whether a tailored prevention plan can improve outcomes and help with costs for people at high risk of coronary heart disease. You may join if you’ve had recent heart events or scans show significant blockage, and if you can follow the visit and app requirements.
HelsinkiAges 30–80 - NCT04588311RecruitingPhase 3
Epoetin to improve outcomes in severe trauma ICU patients
This trial tests epoetin alfa (a blood-building medicine) to help reduce death and severe disability in critically ill trauma patients in the ICU. You may be considered if your ICU team expects a longer stay and the timing after injury is early.
Camperdown, New South WalesAges 18–75 - NCT04631471RecruitingPhase 3
Ibudilast for spinal cord pressure from neck wear
This Phase 3 study tests ibudilast, a medicine, to see if it can improve symptoms in people whose neck arthritis has started compressing the spinal cord. You would still have your usual surgery to relieve the pressure, and then take the study medicine to see if recovery and function improve.
CambridgeAges 18–80 - NCT04704297RecruitingPhase 4
Trigger point shots for low back muscle pain
This trial tests whether injecting sore “trigger points” in low back muscles helps improve chronic low back pain. It compares treatments in people with specific low back muscle pain patterns and excludes several other causes of pain.
Tacoma, WashingtonAges 18 years+ - NCT04715685Recruiting
Mind-body balance program for children with migraine
This trial studies a mind-body balance approach to help reduce symptoms and disability from pediatric migraine. You may join if your child has migraine headaches and can follow study routines, including keeping a headache diary.
Aurora, ColoradoAges 10–17
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Common questions
- Are there clinical trials for disability or chronic disease leading to disablement?
- Yes. Clin2 currently lists 688 recruiting disability or chronic disease leading to disablement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disability or chronic disease leading to disablement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disability or chronic disease leading to disablement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.