Clinical trials
Disability or Chronic Disease Leading to Disablement clinical trials
Below are recruiting disability or chronic disease leading to disablement clinical trials, each written for real people, not researchers. We’re tracking 688 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04876339Recruiting
Sound-based training to improve walking after brain illness
This study tests whether using special sounds (sonification) during gait training can improve walking for people with stroke, Parkinson’s disease, or multiple sclerosis. It may help your walking speed, stamina (fatigue), and overall walking pattern.
PaviaAges Up to 80 years - NCT04903015Recruiting
Study brain effects in retiring pro soccer players
This study looks at how years of playing professional soccer may affect the brain and thinking, using MRI (brain scans) and comparisons to people who had little head-impact sports exposure. You might join if you are a retiring Ligue 1 or Ligue 2 player and meet the injury and health criteria.
StrasbourgAges 32–55 - NCT06007404Recruiting
Understanding metabolism and inflammation in teens
This study looks at how metabolism and inflammation relate to diabetes risk in teenagers. It may help researchers understand why some teens develop type 2 diabetes.
Ann Arbor, MichiganAges 14–18 - NCT04945174Recruiting
Stroke prevention program with exercise and education
This trial tests a structured “stroke school” program that includes supervised physical activity, education, and follow-up coaching to help reduce future stroke and heart problems. It may help people with minor stroke or a TIA who don’t need rehabilitation but do need safer ways to be more active.
Copenhagen, HerlevAges 18 years+ - NCT04976348Recruiting
Heart monitoring registry for teens and adults with heart symptoms
This study registers people who are referred to cardiology or genetics for heart-failure–type symptoms or heart/cardiogenetic screening. It helps doctors understand how monitoring platforms may support diagnosis and follow-up.
Maastricht, LimburgAges 16 years+ - NCT05052541RecruitingPhase 3
Oral cannabis for long-term spine pain
This trial studies whether taking cannabis by mouth can safely reduce chronic spine pain and improve daily comfort. You may be eligible if you have long-lasting spine pain and can follow study rules about stopping or limiting other cannabis and certain other treatments.
Aurora, ColoradoAges 21–84 - NCT05253326Recruiting
Relaxing muscle exercises after spine surgery
This trial tests whether a structured “progressive muscle relaxation” routine can reduce pain and help recovery after spine surgery. You may be asked to learn and practice the relaxation steps even if you’ve never done them before.
Istanbul, ÜsküdarAges 18 years+ - NCT05281809RecruitingPhase 2
CAR T-cell therapy made locally for B-cell blood cancers
This Phase 2 trial tests a locally manufactured CAR T-cell treatment for certain B-cell lymphomas and B-ALL that have limited treatment options left. It may help your immune system attack cancer cells that carry the CD19 marker, potentially as a bridge to transplant for some patients.
Pittsburgh, PennsylvaniaAges 18–79 - NCT05292794Recruiting
CereGate therapy for freezing of gait in Parkinson’s
This trial tests whether CereGate therapy can reduce “freezing of gait,” a walking problem, in people with Parkinson’s disease who already have deep brain stimulation (DBS). If you meet the device and medication stability requirements, the study may help your walking and movement symptoms measured during testing.
Redwood City, CaliforniaAges 21–80 - NCT05336201RecruitingPhase 2
Brain training program for teens with sickle cell disease
This Phase 2 study tests a cognitive (thinking) training program to help teens with sickle cell disease prepare for the changes in their care as they grow older. It may help with skills like learning, attention, and planning for transition to adult care.
Birmingham, AlabamaAges 10–18 - NCT05349006RecruitingPhase 3
Azathioprine for first attack in MOG antibody disease
This Phase 3 trial studies whether azathioprine can help prevent problems after a first attack of MOG antibody–related inflammation of the brain/spinal cord. It’s for adults with a recent first episode and confirmed MOG antibodies.
BordeauxAges 18 years+ - NCT05359796Recruiting
Study of long-term type 1 diabetes symptoms and characteristics
This study looks at what day-to-day health and medical features are like in people who have had type 1 diabetes for many years. It may help researchers better understand long-term needs in type 1 diabetes and guide future care.
Changsha, HunanAges Any age - NCT05359991Recruiting
Exercise study in children and teens with lung or blood conditions
This study tests how safe and effective a structured exercise program is for children and teens. It also compares results between children with sickle cell disease, cystic fibrosis, and healthy peers (and some teens after COVID-19 infection).
Irvine, CaliforniaAges 10–17 - NCT05374681Recruiting
Test a minimally invasive add-on treatment for brain vessel swelling
This trial studies whether an add-on, minimally invasive procedure works better than standard care for a specific brain blood-vessel problem (CSH) that is larger than 10 mm. It may help reduce symptoms or prevent worsening, if you meet the size and location requirements.
Amiens, FranceAges 18 years+ - NCT05402163Recruiting
Testing adaptive DBS for gait, balance, and speech
This trial looks at a new type of Parkinson’s brain stimulation (adaptive DBS) to help with disabling walking, balance, and/or speech problems. It also requires replacing your DBS battery because the researchers need to test the new system’s signals.
Toronto, OntarioAges 18–80 - NCT05459402RecruitingPhase 2/Phase 3
Methadone dose testing for opioid use disorder pain relief
This study compares taking methadone as one dose versus split into two doses to see which approach works better for people who have pain. It’s meant for adults already on a steady methadone program and who can follow study visits and procedures.
Baltimore, MarylandAges 18–100 - NCT05461092RecruitingEarly Phase 1
Nerve blocks to improve pain control after spinal fusion
This early-stage study tests whether a regional nerve block can improve pain control and recovery for older adults having elective lumbar spinal fusion. If you qualify, you may receive a special pain-control injection during surgery to reduce opioid needs and improve recovery comfort.
Iowa City, IowaAges 65 years+ - NCT05471232Recruiting
Genomic testing for youth mental health crises with IDD
This study looks at genetic (DNA) information to understand mental health crises in youth with intellectual and developmental disabilities. It may help doctors learn why these crises happen and improve how future families are supported.
San Diego, CaliforniaAges 7–17 - NCT05476991RecruitingPhase 3
Low-dose colchicine plus ticagrelor to prevent repeat stroke
This Phase 3 study tests whether low-dose colchicine added to ticagrelor (a blood-thinning medicine) helps prevent another ischemic stroke in people whose first stroke was caused by clogged arteries. It aims to lower the risk of repeat stroke after recovery from a recent event.
Paris, ParisAges 18 years+ - NCT05491031Recruiting
MRI scan study to predict disability changes in MS
This study uses MRI scans to predict how quickly disability may worsen in people with multiple sclerosis (MS). It may help doctors spot people at higher risk of progression earlier.
PoitiersAges 18 years+ - NCT05523505Recruiting
Noninvasive brain stimulation to improve adult reading understanding
This study tests whether a safe, non-drug brain stimulation approach can help adults better understand what they read. It aims to see if the treatment improves reading comprehension and related thinking skills.
Nashville, TennesseeAges 18–40 - NCT05532865Recruiting
Biobank study for adults with systemic sclerosis
This study follows adults with systemic sclerosis who are being seen at a specific hospital and asks for consent to store blood and other samples for future research. It may help researchers better understand the disease and develop better tests or treatments over time.
BrestAges 18 years+ - NCT05574634Recruiting
Study of brain signaling and distraction in aging adults
This study looks at how a deep brain area helps people focus and ignore distractions as we get older. You may be invited if you’re a healthy adult and can safely complete brain-related testing.
Blacksburg, VirginiaAges 18–75 - NCT05620719Recruiting
Study delayed headache after head injury in veterans
This study looks at treatment for ongoing headache that starts or gets worse after a mild or moderate head/neck injury in veterans or active-duty service members. It may help by testing an approach aimed at reducing headache burden and improving daily functioning.
Los Angeles, CaliforniaAges 18–70
Hear when a new Disability or Chronic Disease Leading to Disablement trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for disability or chronic disease leading to disablement?
- Yes. Clin2 currently lists 688 recruiting disability or chronic disease leading to disablement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disability or chronic disease leading to disablement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disability or chronic disease leading to disablement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.