Clinical trials
Disability or Chronic Disease Leading to Disablement clinical trials
Below are recruiting disability or chronic disease leading to disablement clinical trials, each written for real people, not researchers. We’re tracking 687 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05650307Recruiting
Heart and metabolic scan study of weight and rehabilitation
This study uses detailed heart scans and information about metabolism (how your body uses energy) to understand how metabolic treatments and heart rehabilitation may affect your health. You may qualify either as someone undergoing bariatric (weight-loss) care or as part of a heart rehabilitation group—or as a healthy comparison group.
Cleveland, OhioAges 18 years+ - NCT05660746RecruitingPhase 2/Phase 3
Infliximab dose tailored to control Crohn’s inflammation
This trial tests a more precise way to start infliximab (a Crohn’s medicine) and adjust dosing based on how your body responds. It aims to better control Crohn’s inflammation early and keep it under control.
Los Angeles, CaliforniaAges 6–22 - NCT05661084Recruiting
Non-surgery brain stimulation for dementia thinking and movement
This study tests whether a non-invasive brain stimulation device (tES) can improve thinking and movement problems in people with dementia. You (and your caregiver, if needed) will be asked to follow the study plan and attend visits so researchers can measure results and safety.
Boston, MassachusettsAges 55 years+ - NCT05689788Recruiting
High-intensity laser treatment for chronic neck pain
This trial tests whether high-intensity laser therapy can reduce long-lasting neck pain and improve daily function. It may help people whose neck pain has lasted at least 3 months and who meet specific pain and disability scores.
Santiago, Las CondesAges 18 years+ - NCT05692973Recruiting
Study tests how reading skill affects thinking
This study looks at how difficulty reading might change how people make judgments and decisions. You may be asked to complete reading and thinking tasks, and the researchers compare results by reading performance.
Excelsior Springs, MissouriAges 8–14 - NCT05710549Recruiting
Brain study of autobiographical memory using brain stimulation
This study looks at how the brain supports remembering your own past experiences. It tests brain mechanisms using brain scanning (MRI) and noninvasive brain stimulation to see how these memory processes work.
Geneva, Canton of GenevaAges 18–85 - NCT05738278Recruiting
Care changes guided by heart rate in non-speaking autistic people
This study tests whether using a person’s heart rate to guide care can improve day-to-day support for autistic people who do not communicate verbally. It’s aimed at people who live in a care home or attend a staffed day program most days of the week.
OsloAges 5–70 - NCT05751525Recruiting
Oral sulfonylurea study for children with KCNJ11-related delay and epilepsy
This study looks at whether switching to an oral sulfonylurea medicine can improve thinking, development, and seizure-related outcomes in children with a specific KCNJ11 gene change. You may be able to join if your child already has this mutation and has been able to take the medicine by mouth.
Chicago, IllinoisAges 2–50 - NCT05761847Recruiting
Medication coaching for kids with many health conditions
This study offers medication therapy management—helping families organize and use their child’s medicines safely and correctly. It’s meant for children with complex, long-term health problems who take many medications.
Aurora, ColoradoAges 2–18 - NCT05767242Recruiting
Early brain tests in babies at language risk
This study looks for early brain signals that may predict future language difficulties in very young children. It compares babies with a family history of language problems to babies without, using safe testing to see what markers show up early.
Bosisio Parini, LCAges 6 months–8 years - NCT05782244RecruitingPhase 2
Sildenafil trial for long-term brain blood-flow problems after TBI
This Phase 2 study tests whether sildenafil (a medication better known for erectile function) can improve long-term symptoms and brain blood-flow issues after a past traumatic brain injury (TBI). It may help by improving blood vessel function in the brain and possibly reducing persistent post-concussion symptoms.
Philadelphia, PennsylvaniaAges 18–70 - NCT05789446Recruiting
Testing a coping and identity skills program for teens
This study tests whether a skills program helps children better cope and build a strong sense of identity. It is offered to early teens and may help with stress and emotional challenges.
Harrisburg, PennsylvaniaAges 11 years+ - NCT05817734Recruiting
Research study to collect health information from adults
This is a research study that collects information about your health and traits to better understand human health and variation. It is mainly for adults who can consent and do not have several specific medical situations listed below.
RehovotAges 18 years+ - NCT05849285Recruiting
Testing a program to support adults with lifelong care needs
This study tests a “Transitional and Lifelong Care” program for adults who had a disability since childhood, and includes their main caregiver or support person. It aims to see how this type of care support may improve experiences and support over time.
London, OntarioAges 21 years+ - NCT05851196Recruiting
Personalized exercise for recurrent low back pain
This study looks at how back muscle features can help tailor an exercise program for people with recurring, non-specific low back pain. It may help by matching exercises to your specific back function and symptoms.
DiepenbeekAges 18–60 - NCT05892510RecruitingPhase 2/Phase 3
Tenecteplase after clot removal for no-reflow stroke
This trial tests whether giving tenecteplase directly into the brain artery after a thrombectomy can improve outcomes when blood flow doesn’t fully return (“no-reflow”) in an emergency stroke. It may help some people by reducing ongoing clot-related blockage after the main clot is removed.
Gold Coast, QueenslandAges 18 years+ - NCT05911568Recruiting
Clot-removal treatment for stroke patients with existing disability
This trial studies whether an endovascular (catheter-based) procedure to treat a certain type of blocked artery can improve outcomes for people who already had trouble functioning before their stroke. You may be considered if your stroke is confirmed early and your scans show the right type and location of blockage.
Phoenix, ArizonaAges 18 years+ - NCT05920174Recruiting
Implant test to help movement in people with severe paralysis
This trial studies whether an implanted device that can record and stimulate brain signals is safe and may improve movement in people with motor disability from certain nerve or brain conditions. It’s for adults with stable, long-lasting paralysis and good brain function who can follow the study plan.
Beijing, Beijing MunicipalityAges 18–80 - NCT05926713Recruiting
Diet supplement plus exercise for muscle loss with lung disease
This trial studies whether adding a dietary supplement to exercise can improve muscle strength in people with muscle loss (sarcopenia) who also have lung disease such as COPD or ILD. It may help you build strength and function without needing urgent hospital care.
TaichungAges Any age - NCT05930145Recruiting
Two clot-retrievers versus one for acute stroke treatment
This trial compares using two clot-retrievers at the same time versus using just one to remove the clot in an acute ischemic stroke. It may help find a more effective approach to restore blood flow and improve recovery.
EssenAges 18 years+ - NCT05935722Recruiting
Home parenting support for parents of young children
This study tests a home-based parenting support program designed for parents who have learning or attention differences (like autism or ADHD). It aims to give tailored strategies to help you manage parenting daily challenges for children aged 0 to 9.
EnköpingAges Any age - NCT05968664Recruiting
Test whether new spinal cord stimulation settings improve chronic pain
This trial studies whether changing the “stimulation pattern” of spinal cord stimulation can reduce long-lasting pain and improve daily function. You might be a good candidate if you have chronic trunk or leg pain and have already tried multiple pain treatments without enough relief.
Houston, TexasAges 22 years+ - NCT05968976Recruiting
DBS surgery guided while awake versus asleep for essential tremor
This study compares two ways of doing a deep brain stimulation (DBS) procedure for people with essential tremor: using guidance while you are awake versus while you are asleep. It aims to find which approach is safer and works better for controlling disabling tremor.
Amsterdam, North HollandAges 18 years+ - NCT05986370Recruiting
Study on back pain and spinal manipulation
This trial tests whether spinal manipulation therapy (a type of hands-on treatment) can help people with long-term low back pain. It also compares their results to healthy volunteers of the same age and sex.
Trois-Rivières, QuebecAges 18–60
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Common questions
- Are there clinical trials for disability or chronic disease leading to disablement?
- Yes. Clin2 currently lists 687 recruiting disability or chronic disease leading to disablement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disability or chronic disease leading to disablement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disability or chronic disease leading to disablement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.