Clinical trials
Disability or Chronic Disease Leading to Disablement clinical trials
Below are recruiting disability or chronic disease leading to disablement clinical trials, each written for real people, not researchers. We’re tracking 686 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06018766RecruitingPhase 2
LAM-001 for lung transplant patients with BOS
This study tests whether the drug LAM-001 can help people who have developed a condition called bronchiolitis obliterans syndrome (BOS) after a double lung transplant. BOS causes a slow decline in lung function, and this trial aims to see if LAM-001 can slow or stop that decline.
San Francisco, CaliforniaAges 18 years+ - NCT06002919Recruiting
MindWalk for older South Asian caregivers of people with cognitive disabilities
This study tests a program that combines physical activity and mindfulness practices to help reduce stress in older South Asian caregivers. Participants will get a Fitbit tracker and receive text messages to support their well-being.
Bolingbrook, IllinoisAges 45 years+ - NCT05911568Recruiting
Clot-removal treatment for stroke patients with existing disability
This trial studies whether an endovascular (catheter-based) procedure to treat a certain type of blocked artery can improve outcomes for people who already had trouble functioning before their stroke. You may be considered if your stroke is confirmed early and your scans show the right type and location of blockage.
Birmingham, AlabamaAges 18 years+ - NCT05892510RecruitingPhase 2/Phase 3
Tenecteplase after clot removal for no-reflow stroke
This trial tests whether giving tenecteplase directly into the brain artery after a thrombectomy can improve outcomes when blood flow doesn’t fully return (“no-reflow”) in an emergency stroke. It may help some people by reducing ongoing clot-related blockage after the main clot is removed.
Gold Coast, QueenslandAges 18 years+ - NCT05849285Recruiting
Testing a program to support adults with lifelong care needs
This study tests a “Transitional and Lifelong Care” program for adults who had a disability since childhood, and includes their main caregiver or support person. It aims to see how this type of care support may improve experiences and support over time.
London, OntarioAges 21 years+ - NCT05851196Recruiting
Personalized exercise for recurrent low back pain
This study looks at how back muscle features can help tailor an exercise program for people with recurring, non-specific low back pain. It may help by matching exercises to your specific back function and symptoms.
DiepenbeekAges 18–60 - NCT05812092Enrolling by invitation
Surgery for one or two levels of neck disc degeneration
This trial studies whether an operation to remove and decompress damaged neck discs (and fuse the area) helps people with painful nerve problems in the neck/arm. It’s meant for cases where non-surgery treatments haven’t worked and imaging shows the problem matches your symptoms.
Fort Worth, TexasAges 18 years+ - NCT05789446Recruiting
Testing a coping and identity skills program for teens
This study tests whether a skills program helps children better cope and build a strong sense of identity. It is offered to early teens and may help with stress and emotional challenges.
Harrisburg, PennsylvaniaAges 11 years+ - NCT05782244RecruitingPhase 2
Sildenafil trial for long-term brain blood-flow problems after TBI
This Phase 2 study tests whether sildenafil (a medication better known for erectile function) can improve long-term symptoms and brain blood-flow issues after a past traumatic brain injury (TBI). It may help by improving blood vessel function in the brain and possibly reducing persistent post-concussion symptoms.
Philadelphia, PennsylvaniaAges 18–70 - NCT05761847Recruiting
Medication coaching for kids with many health conditions
This study offers medication therapy management—helping families organize and use their child’s medicines safely and correctly. It’s meant for children with complex, long-term health problems who take many medications.
Aurora, ColoradoAges 2–18 - NCT05641259RecruitingPhase 1
LP-108 with azacitidine for blood cancers
This trial tests a new drug called LP-108 combined with azacitidine for people with certain blood cancers like acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), or chronic myelomonocytic leukemia (CMML). It aims to see if the combination is safe and helps shrink or control the cancer.
NanchangAges 18 years+ - NCT05661084Recruiting
Non-surgery brain stimulation for dementia thinking and movement
This study tests whether a non-invasive brain stimulation device (tES) can improve thinking and movement problems in people with dementia. You (and your caregiver, if needed) will be asked to follow the study plan and attend visits so researchers can measure results and safety.
Boston, MassachusettsAges 55 years+ - NCT05660746RecruitingPhase 2/Phase 3
Infliximab dose tailored to control Crohn’s inflammation
This trial tests a more precise way to start infliximab (a Crohn’s medicine) and adjust dosing based on how your body responds. It aims to better control Crohn’s inflammation early and keep it under control.
Los Angeles, CaliforniaAges 6–22 - NCT05641116Recruiting
Exercise plus education program for long-lasting Lyme-related symptoms
This trial tests whether a combined program of adapted exercise and therapeutic education can improve long-lasting symptoms that are thought to be related to Lyme disease. It may help people who have symptoms for over 6 months and are not very active currently.
Clermont-FerrandAges 18 years+ - NCT05650307Recruiting
Heart and metabolic scan study of weight and rehabilitation
This study uses detailed heart scans and information about metabolism (how your body uses energy) to understand how metabolic treatments and heart rehabilitation may affect your health. You may qualify either as someone undergoing bariatric (weight-loss) care or as part of a heart rehabilitation group—or as a healthy comparison group.
Cleveland, OhioAges 18 years+ - NCT05620719Recruiting
Study delayed headache after head injury in veterans
This study looks at treatment for ongoing headache that starts or gets worse after a mild or moderate head/neck injury in veterans or active-duty service members. It may help by testing an approach aimed at reducing headache burden and improving daily functioning.
Los Angeles, CaliforniaAges 18–70 - NCT05574634Recruiting
Study of brain signaling and distraction in aging adults
This study looks at how a deep brain area helps people focus and ignore distractions as we get older. You may be invited if you’re a healthy adult and can safely complete brain-related testing.
Blacksburg, VirginiaAges 18–75 - NCT05520983Enrolling by invitation
Behavior program study for teens with learning or thinking differences
This study is testing a “behavioral health” treatment plan designed for teens who have intellectual and/or developmental disabilities. It may help identify which treatment approach works best for different youth needs.
Chicago, IllinoisAges 13–20 - NCT05545384RecruitingPhase 3
Immediate vs delayed azathioprine or rituximab for children with anti-MOG attacks
This Phase 3 trial tests whether starting anti-inflammatory treatment right away is better than waiting, using either azathioprine or rituximab, for children with anti-MOG antibody–related acute demyelinating episodes. It may help reduce future attacks and disability.
BesançonAges 6–17 - NCT05532865Recruiting
Biobank study for adults with systemic sclerosis
This study follows adults with systemic sclerosis who are being seen at a specific hospital and asks for consent to store blood and other samples for future research. It may help researchers better understand the disease and develop better tests or treatments over time.
BrestAges 18 years+ - NCT05491031Recruiting
MRI scan study to predict disability changes in MS
This study uses MRI scans to predict how quickly disability may worsen in people with multiple sclerosis (MS). It may help doctors spot people at higher risk of progression earlier.
PoitiersAges 18 years+ - NCT05461092RecruitingEarly Phase 1
Nerve blocks to improve pain control after spinal fusion
This early-stage study tests whether a regional nerve block can improve pain control and recovery for older adults having elective lumbar spinal fusion. If you qualify, you may receive a special pain-control injection during surgery to reduce opioid needs and improve recovery comfort.
Iowa City, IowaAges 65 years+ - NCT05459402RecruitingPhase 2/Phase 3
Methadone dose testing for opioid use disorder pain relief
This study compares taking methadone as one dose versus split into two doses to see which approach works better for people who have pain. It’s meant for adults already on a steady methadone program and who can follow study visits and procedures.
Baltimore, MarylandAges 18–100 - NCT04395495Recruiting
RASopathy disorder study biobank for kids and families
This study collects and stores health samples and information from people with RASopathy conditions (like Noonan or Costello syndromes) and from family members who may not have the condition. It helps researchers understand these disorders and supports future studies that could lead to better care.
Cincinnati, OhioAges Any age
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Common questions
- Are there clinical trials for disability or chronic disease leading to disablement?
- Yes. Clin2 currently lists 686 recruiting disability or chronic disease leading to disablement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disability or chronic disease leading to disablement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disability or chronic disease leading to disablement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.