Clinical trials
Disability or Chronic Disease Leading to Disablement clinical trials
Below are recruiting disability or chronic disease leading to disablement clinical trials, each written for real people, not researchers. We’re tracking 687 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07335718Recruiting
Radiofrequency therapy for low back pain from disc herniation
This trial tests if a type of radiofrequency treatment (TECAR therapy) can reduce pain and improve function and quality of life for people with low back pain caused by a herniated disc. It involves an exercise program along with the treatment.
AnkaraAges 20–60 - NCT07338292Recruiting
Virtual reality for pain and anxiety in urology procedures
This study tests if using virtual reality can reduce pain and anxiety during outpatient urology procedures like circumcision, prostate biopsy, or flexible cystoscopy. If you are having one of these procedures for the first time, you may be able to participate.
PadovaAges 18–99 - NCT07344506RecruitingPhase 4
Cure H. pylori: New combination therapy for stomach infection
This trial tests a new combination of medications to treat H. pylori, a common stomach infection that can cause ulcers. It aims to find a more effective treatment with fewer side effects.
KarachiAges 18 years+ - NCT07446998RecruitingPhase 2
Study on enobosarm for weight loss in older adults on semaglutide
This trial tests if adding enobosarm (a muscle-preserving drug) to semaglutide (a weight-loss medication) can help older adults maintain muscle and improve physical function while losing weight. It may be an option for people who are already taking semaglutide and want to prevent muscle loss.
Phoenix, ArizonaAges 65–100 - NCT07361094RecruitingPhase 1
CAR-T therapy for autoimmune disease after prior treatment
This trial tests a new CAR-T cell therapy that targets two proteins (CD19 and BCMA) on immune cells. It is for people with certain autoimmune diseases (like lupus or scleroderma) that have not responded well to standard treatments or have relapsed after prior cell therapy.
BeijingAges 18–70 - NCT07370792Recruiting
Genetic mapping for multiple birth defects or intellectual disability
This study uses a new genetic technique to find hidden causes in people with multiple birth defects or intellectual disability who had standard genetic tests come back normal. It might help identify a genetic reason when other tests did not.
Clermont-FerrandAges Any age - NCT07383038Recruiting
Mobilization with movement for rotator cuff injuries
This trial tests a gentle hands-on therapy technique called 'mobilization with movement' to help people with partial rotator cuff tears or tendinopathy. It aims to improve shoulder pain and movement.
KırşehirAges 18–65 - NCT01087320Recruiting
Genetic testing study to find causes of rare disorders
This study uses genome (DNA) sequencing to look for the genetic cause of rare disorders, especially when the cause is unknown. It may help some families better understand what is driving the condition, using genetic information from the affected person and often their parents.
Bethesda, MarylandAges 4 weeks–99 years - NCT00404560Recruiting
Blood tests to study infection risk and immune problems
This study looks at how the immune system works in people who have—or might have—an increased risk of infections. It also enrolls their healthy blood relatives so researchers can compare immune features; results may help doctors understand who is at higher risk and why.
Bethesda, MarylandAges 1 month–100 years - NCT00001355Recruiting
Understanding immune system cell defects and family patterns
This research study investigates problems with immune system cells called phagocytes that help fight infections. Researchers will study patients with suspected immune defects and their blood relatives to better understand these conditions and develop better care.
Bethesda, MarylandAges 1 month–100 years - NCT01581580Recruiting
Deep brain stimulation surgery for movement disorders
This study looks at whether deep brain stimulation surgery can help people with certain movement problems, chosen by a specialized team. You may be considered if medicines (or other treatments) aren’t controlling your symptoms well enough or if the condition causes major disability.
Bethesda, MarylandAges 18–99 - NCT02119611Recruiting
Deep brain stimulation for Parkinson’s, dystonia, or tremor
This study tests deep brain stimulation (DBS), a therapy that sends electrical signals to the brain, for movement problems like Parkinson’s disease, dystonia, and essential tremor. It may help people whose symptoms are not controlled enough with medications, or who already have a DBS device and need ongoing management.
Bethesda, MarylandAges 18–100 - NCT02542683Recruiting
Physical activity program to support children’s brain development
This study looks at whether a structured physical activity program can support thinking and brain development in children around age 2–5. Your child may be eligible if they are having certain surgeries or fit a matched “control” group and do not have specific neurologic or heart-related issues.
New York, New YorkAges 2.5 years–6 years - NCT02592291Recruiting
Using a phone app to help manage long-term health needs
This study tests a mobile phone system that helps people with long-term, complex health conditions manage daily life and get support. If you can use a smartphone and pass the study checks, you may be able to try the self-management tools.
Pittsburgh, PennsylvaniaAges 12 years+ - NCT02240862Recruiting
Carotid artery disease registry for symptom and risk groups
This is a registry that enrolls adults with narrowed carotid arteries (with symptoms or no symptoms). It collects health and treatment information to better understand which patients benefit from procedures and when.
Baltimore, MarylandAges 18–80 - NCT02302482Recruiting
Tracking memory changes and personal independence over time
This study follows people who are newly evaluated in a memory clinic to better understand what predicts how memory and independence may change. It may help clinicians plan care that supports autonomy as the condition progresses.
Caluire-et-CuireAges 65 years+ - NCT02630121RecruitingPhase 4
Nasal spray treatment to reduce mild sleep apnea congestion
This study tests whether using oxymetazoline with fluticasone nasal spray can improve mild obstructive sleep apnea by lowering nasal congestion. If your nose stays blocked most days despite current spray use, this may help your breathing during sleep.
Tampa, FloridaAges 18–65 - NCT02917460Recruiting
Join a children’s genomic sample and data library
This study collects and stores DNA samples and related health information from people of all ages. It helps researchers understand childhood diseases better and may support future discoveries and treatments.
San Diego, CaliforniaAges Any age - NCT03109288RecruitingPhase 1/Phase 2
Biomarker-guided combination treatment for residual multiple sclerosis activity
This early-phase study tests combination treatments for multiple sclerosis (MS) based on lab “biomarkers” found in the spinal fluid. It aims to reduce ongoing MS activity and help determine which treatment combinations may work best for different people.
Bethesda, MarylandAges 18–120 - NCT07672938Recruiting
Olive supplement and Mediterranean diet for mild memory loss
This trial tests whether a dietary supplement made from olive polyphenols, combined with following a Mediterranean diet, can help protect thinking and memory in people with mild cognitive impairment (MCI). It may be a good fit if you have early memory changes and want to try a nutrition-based approach.
Thessaloniki, Central MacedoniaAges 50–85 - NCT07403331Recruiting
Nerve pain in legs: spinal cord stimulation plus team care
This trial tests a treatment bundle that combines a spinal cord stimulator (a device that sends mild electrical pulses to your spine to block pain signals) with a team of specialists (like a psychologist and physical therapist) to reduce chronic nerve pain in the legs and improve your ability to move and function.
OsloAges 18–60 - NCT07444047Recruiting
MRI study of brain lesions in older MS patients
This study uses MRI scans to compare brain lesions in older patients with multiple sclerosis versus those with small vessel disease. It aims to improve how doctors tell apart these conditions and may lead to better treatment choices.
Oslo, OsloAges 50–80 - NCT07444931Recruiting
Predicting cardiac arrest risk in heart disease patients
This study looks at factors that may help predict sudden cardiac arrest in people with coronary artery disease. If you have a recent diagnosis of significant blockage or a heart attack, joining this trial could help improve risk assessment.
HaderaAges 18–75 - NCT07460531Recruiting
Physical activity and heart health in chronic heart failure
This study looks at how physical activity affects heart outcomes in people with chronic heart failure. If you have a pedometer or activity tracker, you may be able to join.
Munich, BavariaAges 18 years+
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Common questions
- Are there clinical trials for disability or chronic disease leading to disablement?
- Yes. Clin2 currently lists 687 recruiting disability or chronic disease leading to disablement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disability or chronic disease leading to disablement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disability or chronic disease leading to disablement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.