Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,576 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06584357Recruiting
Digital and blood markers linked to brain scans in older adults
This study is looking for older adults (60–90) who are either cognitively normal, have mild cognitive impairment (MCI), or have mild-to-moderate Alzheimer's dementia. It aims to see how digital tests and blood-based markers relate to brain scans (amyloid and tau PET). You will need a study partner, undergo MRI and PET scans, and give blood samples.
Atlantis, FloridaAges 60–90 - NCT06585384RecruitingPhase 1
Safety of etanercept with contrast ultrasound for Alzheimer's
This study tests whether combining a drug called etanercept with repeated contrast ultrasound is safe for people with mild Alzheimer's. It aims to see if this approach can help slow the disease.
ParisAges 50–85 - NCT06585449RecruitingPhase 1
Study of ALN-HTT02 for Huntington's disease
This trial tests an experimental drug called ALN-HTT02 for people with Huntington's disease. The goal is to see if it can help manage symptoms. Participants must have stage 2 or early stage 3 Huntington's disease.
EdmontonAges 25–70 - NCT06588231Recruiting
Personalized exercise for older adults with heart disease
This study tests whether a personalized exercise program can help older people (60–75) with stable coronary heart disease improve their heart health. You would work with healthcare professionals to get an exercise plan tailored to your condition.
Nanjing, JiangsuAges 60–75 - NCT06588439Recruiting
Cognitive-motor training for Parkinson's
This study tests a type of training that combines thinking tasks with movement exercises to see if it can improve symptoms in people with Parkinson's disease.
TaipeiAges 40–80 - NCT06588699RecruitingPhase 2
Digoxin for NASH liver disease study
This trial tests if the heart medication digoxin can help people with NASH (fatty liver disease with inflammation), who have moderate liver scarring. You will receive digoxin or a placebo for 24 weeks and have a liver biopsy before and after treatment to see if the medication reduces liver damage.
New Haven, ConnecticutAges 18–75 - NCT06588920Recruiting
Brain activity, thinking, and walking study for Parkinson's
This study looks at how brain activity relates to thinking and walking in people with Parkinson's disease. It may help understand the connections between these functions.
TaipeiAges 40–80 - NCT06591975Recruiting
Upper extremity function and balance in Parkinson's disease
This study looks at how arm and hand function relates to balance and mobility in people with Parkinson's disease. Understanding this link may lead to better therapy approaches.
SivasAges 18–80 - NCT06593951Recruiting
EPM1 natural history study
This study will follow people with EPM1 over time to better understand the disease. It is a registry, meaning you will share information through video calls and questionnaires, with no experimental treatments involved.
Boston, MassachusettsAges Any age - NCT06595511Recruiting
Combined sound, light, and games for Alzheimer's
This study tests a new approach combining special audio-visual stimulation (at 40 Hz) with cognitive games to see if it can help people with Alzheimer's disease. It also includes a group of healthy older adults for comparison.
Istanbul, BeykozAges 60–86 - NCT06595784Recruiting
COPD and heart disease study
This study looks at people who have both COPD (a long-term lung condition) and a heart problem. The goal is to learn more about how these two conditions affect each other and to help doctors provide better care.
AlexandroupoliAges 35–99 - NCT06595992Recruiting
Observing moderate aortic valve disease over time
This study follows people with moderate aortic valve disease to learn how their condition changes. It does not test a new treatment but will help doctors better understand the disease.
Hangzhou, ZhejiangAges 18 years+ - NCT06597851Recruiting
Insulin resistance and heart artery health: a study for chest pain patients
This study looks at how insulin resistance affects tiny heart arteries in people who have chest pain and signs of heart stress on tests, but do not have major blockages in their heart arteries. It aims to understand why some people have heart symptoms even when their main arteries appear clear.
Verona, VRAges 18 years+ - NCT06598891Recruiting
Balance training for Parkinson's disease
This study tests a special balance training program for people with Parkinson's disease. It aims to see if it can improve walking and reduce falls.
TaoyuanAges 20 years+ - NCT06598878Recruiting
AR-assisted walking training for Parkinson's
This trial tests walking training with augmented reality (AR) goggles to help with movement in Parkinson's disease. It may help improve your gait and balance.
TaoyuanAges 20 years+ - NCT06600178RecruitingPhase 1
Heart medication for women with chest pain and small vessel disease
This trial tests a diabetes medication called SGLT2 inhibitors to see if it can improve blood flow to the heart and reduce chest pain in women who have small vessel heart disease (microvascular dysfunction) but not blocked large arteries. Participants will take the medication and be monitored for symptom relief and heart function improvements.
Charlottesville, VirginiaAges 18 years+ - NCT06087926Recruiting
TMS for apathy in Parkinson's disease
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help improve apathy, or loss of motivation, in people with Parkinson's disease. You must have had symptoms for at least 4 years and be on stable Parkinson's medications.
Chapel Hill, North CarolinaAges 55–80 - NCT07213219Recruiting
PET-MRI scan for Parkinson's with sleep behavior disorder
This trial uses a combined PET and MRI scan to study the brain's reward system in people with Parkinson's disease who also have REM sleep behavior disorder (RBD). It aims to understand how the brain changes and may help guide future treatments.
Clermont-FerrandAges 45–80 - NCT05670132Recruiting
Heart and brain rehab for youth with congenital heart disease
This trial tests a combined heart and brain rehabilitation program for young people with moderate to complex congenital heart disease. The goal is to improve both heart health and thinking skills, such as memory and attention.
BrusselsAges 8–25 - NCT07091682Recruiting
A trial of a dissolvable heart stent for long blockages
This trial tests a new type of stent made from magnesium that slowly dissolves over time. It is for people who have a long blockage in a heart artery that has not been treated before and may be a good option for those who are stable and have not had a recent heart attack.
ErfurtAges 18–80 - NCT03121001RecruitingPhase 2
Transplant from a half-matched donor for aggressive sickle cell
This Phase 2 study tests a “half-matched” stem cell transplant to treat people with aggressive sickle cell disease. It may help by replacing the blood system using stem cells from a related donor who is close but not fully matched.
Chicago, IllinoisAges 16–60 - NCT06956703Recruiting
Nottingham IBD study testing new treatments
This study looks at people with active Crohn's disease or ulcerative colitis starting a new type of medication (anti-TNF, ustekinumab, upadacitinib, or vedolizumab), as well as people without IBD having a routine colonoscopy. It aims to collect information to better understand how these treatments work.
Nottingham, NottinghamshireAges 16 years+ - NCT06836609RecruitingPhase 1/Phase 2
Study of a new drug for fatty liver disease (MASLD/MASH)
This study tests a new drug called ALN-CIDEB for people with fatty liver disease (MASLD or MASH). The goal is to see if it can reduce liver fat and improve liver health. You may qualify if you have a higher BMI and evidence of liver fat on imaging tests.
Chandler, ArizonaAges 18–65 - NCT06736899Recruiting
Orbital atherectomy versus standard care for calcified branch blockages
This trial compares a special device called orbital atherectomy to the usual procedure for treating hardened, calcified blockages that occur where a coronary artery branches. It aims to see which approach works better for patients needing a stent.
AlicanteAges 18 years+
Hear when a new Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,576 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.