Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,374 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07422532Recruiting
Automated insulin delivery for type 2 diabetes on dialysis
This trial tests an automated insulin pump system (Omnipod 5) that adjusts insulin automatically to help keep blood sugar levels stable. It is designed for people with type 2 diabetes who are on hemodialysis for kidney failure.
DerbyAges 18 years+ - NCT05037968Recruiting
Test bone graft materials for multi-level back fusion surgery
This trial compares two bone-graft materials to help bones heal after back fusion surgery using a rod/screw system. It may help people who have ongoing back or leg pain despite at least 3 months of non-surgical treatments.
Hartford, ConnecticutAges 18 years+ - NCT06192160RecruitingPhase 2
New TB drug combinations for drug-sensitive lung TB
This trial tests new combinations of TB medicines for people with active lung TB that is sensitive to standard drugs. It aims to find safer, shorter treatments that work just as well or better than current options.
GaboroneAges 18 years+ - NCT07124559RecruitingPhase 1/Phase 2
TB prevention study for children with and without HIV
This study tests a daily combination of two medicines, rifapentine and isoniazid, to prevent tuberculosis (TB) in children under 13 years old. It aims to see if this short treatment is safe and works well for kids, including those living with HIV.
GaboroneAges Up to 13 years - NCT07296744Recruiting
Study of a heart pump for high-risk angioplasty
This trial tests a new device called the Supira system to support the heart during a high-risk procedure to open blocked arteries. It is for people who are stable enough to wait for the procedure (not in emergency or shock).
Loma Linda, CaliforniaAges 18–90 - NCT00044122Recruiting
Study of mast cell growth in people with mastocytosis
This study looks at what causes mast cells to grow too much in people with mastocytosis. It may help researchers find better ways to diagnose or treat this condition. You can take part in person or by telehealth.
Bethesda, MarylandAges 1 day–80 years - NCT03610802Recruiting
Send blood samples to study genetic and immune differences
This study collects blood (and sometimes related samples) to learn how genes and the immune system work in people with primary immunodeficiency (PID) or in family members who may not have it. The goal is to improve understanding of rare immune conditions and help guide future care.
Bethesda, MarylandAges 1 day–99 years - NCT03481829Recruiting
Long-term study tracking health factors from pregnancy
This study follows pregnant mothers and their babies for years to understand how early life factors can affect health later. If you qualify, you and your child(ren) will be asked to stay in the research study for at least 3 years after delivery.
Phoenix, ArizonaAges 1 day–99 years - NCT00001467Recruiting
Study of genes in immune disorders
This research looks at how inherited (genetic) changes may affect the immune system in people with immune problems. It may help by improving understanding of these conditions and, in some cases, guiding faster care for a baby after birth.
Bethesda, MarylandAges 1 day–101 years - NCT06855537RecruitingPhase 4
Treating unstable plaques that are not fully blocked
This trial compares treatments for heart patients who have a dangerous, but not fully blocking, fatty plaque in their arteries. It aims to see if treating these plaques with a stent or balloon can prevent future heart problems.
Beijing, Beijing MunicipalityAges 18–80 - NCT01193088Recruiting
Genetics study for Charcot-Marie-Tooth disease
This study looks at genes linked to Charcot-Marie-Tooth disease (CMT), a condition that affects nerves in the arms and legs. It aims to find new causes and understand why symptoms vary. If you join, you may give a blood or saliva sample for genetic testing.
Los Angeles, CaliforniaAges Any age - NCT07444580RecruitingPhase 1
Gene-silencing drug for prion disease
This study tests a new drug that targets the genetic material causing prion disease, aiming to slow or stop the disease. It's for people with symptoms or those at high genetic risk, and involves regular check-ups and spinal taps.
Boston, MassachusettsAges 18 years+ - NCT07877688Recruiting
Looking for rare disease genes in your DNA
This study will read the DNA (the genetic instructions) of people with rare diseases who do not yet have a diagnosis, to try to find the cause. It may help you get answers about your condition.
GenovaAges birth–17 years - NCT07674277Recruiting
Virtual reality for pain relief in sickle cell crisis
This study tests whether using a virtual reality headset can help reduce pain for adults with sickle cell disease during a painful crisis. The trial aims to see if this non-drug approach can improve comfort while receiving IV pain medication.
Baltimore, MarylandAges 18–88 - NCT07878884Recruiting
Light therapy with lung rehab for severe COPD
This trial tests whether adding light therapy to a standard exercise program helps people with severe COPD breathe better and do more in their daily lives. It might be especially helpful if you have advanced COPD and can still walk.
Porto Alegre, Rio Grande do SulAges 18–90 - NCT07877272Recruiting
Better liver testing for high-risk fatty liver disease
This study tests a more detailed way to examine the liver in people with fatty liver disease who also have other health risks. The doctors want to see if this extra testing helps decide whether you need treatment.
MünsterAges 18 years+ - NCT07877519Recruiting
Sedation options for pulsed field ablation in atrial fibrillation
This study compares two ways to keep patients comfortable during a procedure called pulsed field ablation for atrial fibrillation: conscious sedation (you're awake but relaxed) versus general anesthesia (you're fully asleep). The goal is to find which method works better and is safer for patients.
Beijing, Beijing MunicipalityAges 18–80 - NCT07744126RecruitingPhase 2
Combination drug therapy for head and neck cancer that has spread
This trial tests a new combination of two drugs (telisotuzumab adizutecan and pembrolizumab) for people with head and neck cancer that has come back or spread and cannot be cured with local treatments. The goal is to see if this combination can help control the cancer and to find the best dose.
Duarte, CaliforniaAges 18 years+ - NCT05147701RecruitingPhase 1
Testing stem cell treatment for NAION safety
This Phase 1 study tests whether lab-made stem cells taken from donated umbilical cord are safe for people with NAION. It mainly looks for side effects and safety rather than proving the treatment works.
Naples, FloridaAges Any age - NCT03819803RecruitingPhase 3
Fecal transplant for gut graft-versus-host disease
This study tests whether restoring healthy gut bacteria using a fecal microbiota transplant can improve steroid-refractory gut graft-versus-host disease (aGvHD) after stem cell transplant. If your gut symptoms are your first episode and your stool bacteria diversity is low, this trial may be an option worth screening for.
Graz, StyriaAges 18–70 - NCT06894095Recruiting
Heart and blood vessel imaging study for adults with coronary CT
This study collects heart and blood vessel images from people who have already had a coronary CT scan. It aims to learn more about heart health and may help future patients.
Nanjing, JiangsuAges 18 years+ - NCT04141605Enrolling by invitation
Heart transplant candidates matched for better heart preservation
This study creates a worldwide registry and information database to help improve how donor hearts are preserved for transplant. If you are a heart transplant candidate, your details may be recorded to see what matching and preservation approaches work best.
Stanford, CaliforniaAges Any age - NCT06190717Recruiting
Ultrasound implant to help dialysis fistula mature
This study tests whether a special ultrasound implant (EchoMark) helps a new dialysis fistula mature properly. It involves people with advanced kidney disease who are starting or already on dialysis and are having a fistula created in the upper arm.
Dothan, AlabamaAges 18–84 - NCT07492641RecruitingPhase 3
A new drug plus letrozole for advanced HR+ breast cancer
This trial tests a new medicine (BGB-43395) combined with letrozole against the usual CDK4/6 inhibitor plus letrozole. It is for people with advanced or metastatic HR-positive, HER2-negative breast cancer who have not yet had treatment for advanced disease.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,374 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.