New TB drug combinations for drug-sensitive lung TB
Treatments studied
Part of Infections, Lungs & breathing clinical trials.
This trial tests new combinations of TB medicines for people with active lung TB that is sensitive to standard drugs. It aims to find safer, shorter treatments that work just as well or better than current options.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have active TB in your lungs, confirmed by a test (Xpert) showing 'medium' or 'high' bacteria levels within the last week.
- Your TB bacteria are sensitive to the standard drugs isoniazid and rifampin (not resistant).
- You are not pregnant, breastfeeding, or planning pregnancy in the next year, and you agree to use effective birth control if needed.
- You are at least 18 years old and weigh at least 35 kg (about 77 pounds).
- Your liver, kidney, and blood counts are within acceptable ranges, and you have no serious heart rhythm issues or other major medical problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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