Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,583 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04046042Recruiting
Virtual reality during dialysis, comparing first vs last
This trial tests whether using virtual reality during hemodialysis affects how patients feel or do during treatment. It compares using virtual reality at the beginning of the dialysis session versus the end.
Manises, ValenciaAges 18 years+ - NCT05345431Recruiting
Check whether a leg-artery nerve procedure helps poor circulation
This trial looks at whether endovascular denervation (a catheter-based nerve-targeting procedure inside blood vessels) can improve symptoms and circulation in people with peripheral arterial disease (PAD). It may help if you have PAD that causes walking problems or ongoing lower-leg symptoms.
Nanjing, JiangsuAges 18–75 - NCT04123431Recruiting
Study of an hip cup implant used in planned hip replacements
This trial studies a specific hip replacement hip “cup” implant used during planned total hip replacement surgery. It may help confirm how well this implant performs in real-world patients who are getting surgery for non-traumatic reasons.
WorthingAges 18 years+ - NCT04343365Recruiting
Using tumor evolution to guide treatment choices
This trial uses information from your tumor’s changes over time to help your care team suggest treatment options. It may help people who are unlikely to be cured with standard treatment by testing new, personalized strategy plans.
Tampa, FloridaAges Any age - NCT02860364Recruiting
Checking different cooling levels during part of heart surgery
This trial compares two cooling temperatures during an “aortic hemiarch” operation to see which approach is safer and better for brain protection. It may help guide surgeons on the best cooling strategy for some planned heart surgeries.
Boston, MassachusettsAges 18 years+ - NCT03236987RecruitingPhase 3
Clarithromycin versus azithromycin for lung MAC infection
This Phase 3 trial compares two antibiotics—clarithromycin and azithromycin—to treat lung infection caused by Mycobacterium avium complex (MAC). It may help by showing which antibiotic works better and is safer for people who need MAC treatment.
Amiens, PicardieAges 18 years+ - NCT02154035Recruiting
Measuring HIV reservoir in Ugandans with suppressed virus
This study in Uganda looks at the HIV 'reservoir' (where the virus hides in the body) in people whose HIV is already well-controlled with medications. It involves blood draws and genetic testing to learn more about the virus.
KalisizoAges 18–49 - NCT03635255Recruiting
Testing heart disease blood markers to predict heart events
This study looks at tiny molecules in your blood to see how they relate to future heart problems in people with coronary artery disease or other cardiovascular disease. If your results suggest higher or lower risk, it may help doctors better predict who could have adverse cardiovascular outcomes.
TaipeiAges 20 years+ - NCT02301663Recruiting
Stress test study of heart blood-flow issues in adults
This study tests a new kind of stress test to understand how small blood-vessel heart problems relate to heart relaxation problems in people with angina (chest pain) but no blocked arteries. It may help doctors learn better ways to diagnose and guide treatment for these conditions.
Los Angeles, CaliforniaAges 18–60 - NCT01193647Enrolling by invitation
Study genetics that may raise rotator cuff injury risk
This study looks at genetic (inherited) factors that may make some people more likely to develop rotator cuff tears. You may be able to join if you’ve had a shoulder MRI for pain or you’re a close family member of someone with a documented tear.
Salt Lake City, UtahAges 18 years+ - NCT05316805Recruiting
Study for type 2 inflammatory skin rashes and hives
This study looks at people with certain types of inflammatory skin conditions to improve how they are diagnosed and treated. It may help your care team by using a standardized approach, but you must be able to complete questionnaires and consent to participate.
BeijingAges Any age - NCT04777357RecruitingPhase 3
Cariprazine for bipolar depression in ages 10 to 17
This Phase 3 study tests whether cariprazine can improve depression symptoms in children and teens with bipolar I disorder, and also tracks side effects. It may help if your depressive episode is ongoing and you meet specific mood and screening score requirements.
Bentonville, ArkansasAges 10–17 - NCT04083183RecruitingPhase 1/Phase 2
Testing radiation plus antibody therapy for certain non-cancer diseases
This early-phase study tests a conditioning treatment using total-body irradiation and a radioactive antibody (called astatine-211) before a stem cell transplant for non-cancer conditions. The goal is to improve how well the donor cells take hold and are tolerated.
Seattle, WashingtonAges 18–49 - NCT04914468Recruiting
Study registry for mitral valve replacement by catheter
This study keeps a registry of adults who have a mitral valve problem and are being evaluated for a catheter-based mitral valve replacement. It helps doctors understand what treatments are used and how patients do.
HamburgAges 18–110 - NCT04206852Recruiting
Balloon treatment for chronic blood-clot lung vessel disease
This trial tests whether a procedure called balloon pulmonary angioplasty is safe and effective for people with chronic thromboembolic disease in the lungs, especially when surgery isn’t an option. If you have CTEPH, it may help improve lung blood flow and symptoms.
BeijingAges 18 years+ - NCT04619355Recruiting
People who had a special heart scan during stent placement
This study follows people who already had a stent put in (PCI) using a special imaging test (NIRS-IVUS) to look at heart outcomes over time. If you agreed and can attend follow-up visits, this registry may help doctors better understand how this imaging-guided approach performs.
SeoulAges 19 years+ - NCT04484675RecruitingPhase 4
Milrinone during heart surgery for severe pulmonary hypertension
This trial tests whether giving milrinone through a vein and inhaled during mitral valve surgery helps people with severe pulmonary hypertension. The goal is to improve heart and lung blood-flow stability around the time of surgery.
Zagazig, Sharqia ProvinceAges 18 years+ - NCT04467333Recruiting
Registry for lung cancer patients at a pulmonary hypertension center
This is a hospital registry study that collects information from people with lung cancer. It looks at pulmonary hypertension (high blood pressure in the lungs) in relation to lung cancer, which may help doctors understand risk and care needs.
Giessen, HesseAges 18 years+ - NCT04335773Recruiting
Study of COVID-19 in hospitalized children
This study looks at children (ages 0 to 18) who are in the hospital with suspected COVID-19. It aims to understand what factors affect outcomes and how the immune system responds.
LørenskogAges Up to 18 years - NCT04197232Recruiting
Safety study of biologics in pregnancy for newborns
This trial looks at whether biologic medicines used during pregnancy are safe for the baby after birth. If your baby was born to a mother taking a biologic for an autoimmune disease, this study may be trying to track and confirm newborn safety outcomes.
Milan, LombardyAges 1 day–12 years - NCT04542720Recruiting
Nerve-Pressure Surgery Alone or With Spine Fusion
This trial compares two surgical options for the level just above a prior lumbar fusion: removing pressure on the nerve versus removing pressure plus adding a fusion. It may help determine which approach better treats ongoing nerve-related symptoms when other non-surgical treatments have not worked.
Boston, MassachusettsAges 18 years+ - NCT04526431Recruiting
Tacrolimus dose study in early kidney transplant patients
This study looks at how tacrolimus (a rejection-preventing medicine) should be dosed in the first days to years after a kidney transplant. It may help personalize dosing by comparing different patient groups, including using genetic testing.
Grenoble, Auvergne-Rhône-AlpesAges 18 years+ - NCT04156893RecruitingPhase 1/Phase 2
RH-matched blood transfusions for sickle cell patients
This study tests whether giving red blood cells matched to your child’s RH (a blood marker) can improve safety and fit for people with sickle cell disease who need regular transfusions. It may help reduce mismatches by using blood units selected to match the child’s blood type more closely.
Philadelphia, PennsylvaniaAges 6 months+ - NCT06472973Recruiting
Addiction support after liver transplant
This trial tests a special addiction support program for people who have had a liver transplant because of alcohol-related liver disease. The goal is to help them stay healthy and avoid drinking again.
BesançonAges 18 years+
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,583 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.