Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,353 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT00542230Recruiting
Blood sample study for sickle cell trait and controls
This study collects blood samples to learn more about sickle cell-related genetics and biology. You might benefit indirectly by helping researchers understand the condition, even though this is laboratory research rather than a medication trial.
Bethesda, MarylandAges 18–100 - NCT00001406Recruiting
Understanding eosinophil behavior in rare blood and tissue conditions
This research study examines how eosinophils (a type of white blood cell) behave and function when they become abnormally high in the blood or tissues. Researchers want to understand these conditions better to potentially improve treatment options.
Bethesda, MarylandAges 1–100 - NCT00128973Recruiting
Study immune system problems in people with unusual infections
This study looks at how the immune system works in people who have abnormal immune function, often shown by unusual or repeated infections or long-lasting inflammation. It may involve tests using blood samples and storage of blood for future research.
Bethesda, MarylandAges Any age - NCT00977977RecruitingPhase 2
Rituximab plus cyclosporine for membranous kidney disease
This trial tests whether rituximab (an immune-targeting medicine) plus cyclosporine (another immune medicine) can better control protein leakage in the urine for people with idiopathic membranous nephropathy. It may help reduce long-lasting kidney damage risk when standard treatments like ACE inhibitor or ARB don’t control the protein level.
Bethesda, MarylandAges 18–90 - NCT00001853Recruiting
Heart disease risk study in Black adults
This study looks at how obesity and blood fat (triglyceride) levels affect heart disease risk differently in Black men and women. You may join if you're a healthy Black adult between 18 and 70, without diabetes.
Bethesda, MarylandAges 18–70 - NCT00024479Recruiting
Understanding how rheumatic diseases develop over time
This research study follows people with known or suspected rheumatic diseases (like arthritis, lupus, or similar conditions) to learn how these conditions change and progress naturally. By tracking your health over time, researchers hope to better understand these diseases and improve treatments.
Bethesda, MarylandAges 18–100 - NCT00001539Recruiting
Lyme disease study's treatment and recovery health
This study looks at the health of people who have had Lyme disease, including those with ongoing symptoms after treatment, and those who have recovered or never had it. It aims to understand the disease and find better ways to manage it.
Bethesda, MarylandAges 13–99 - NCT00794352Recruiting
Studying immune brain and nerve conditions with tests and samples
This study looks at how immune-related brain or spinal cord illness shows up using exams, MRI scans, and sometimes a spinal fluid test (lumbar puncture), plus collected blood and other samples. It may help researchers better understand these conditions and improve future diagnosis or treatments.
Bethesda, MarylandAges 1 month–99 years - NCT00001979Recruiting
Understanding Immune System Kidney Disease
This research study looks at kidney diseases caused by the immune system—conditions where your body's defense system mistakenly attacks the kidneys. Researchers will study your medical history, blood, and urine to better understand these diseases and potentially improve treatment.
Bethesda, MarylandAges 10–99 - NCT00344331Recruiting
Testing blood and MRI markers for Niemann-Pick type C
This study measures biochemical (blood/biologic) markers and may use clinical evaluation and MRI to better understand Niemann-Pick disease type C. It could help improve how the condition is tracked and understood over time.
Bethesda, MarylandAges 1 day–120 years - NCT01168271Recruiting
Study malaria risk factors in pregnancy and young children
This study looks at why some people get malaria during pregnancy, and how young children’s bodies respond early in life. It may help researchers understand who is more likely to get malaria and why, which could guide future prevention and care.
BamakoAges 1 day–45 years - NCT06455800Recruiting
Severe lung disease in childhood
This study looks at severe lung disease in children. It may help doctors better understand and treat these conditions.
OdenseAges 1 day–18 years - NCT06638944RecruitingPhase 2
Wearable feedback device for swallowing therapy in stroke or Parkinson's
This study tests a wearable device that provides feedback to help improve swallowing in people with stroke or Parkinson's disease. It may help make swallowing therapy more effective by showing real-time progress during exercises.
Champaign, IllinoisAges 50–90 - NCT01193075Recruiting
Tracking the course of charcot-marie-tooth disease over time
This study follows people with certain types of Charcot-Marie-Tooth disease (CMT), a genetic nerve disorder, over time to understand how the condition progresses. It also includes healthy volunteers as controls, and no experimental treatments are given.
Los Angeles, CaliforniaAges Any age - NCT07238556Recruiting
Digital exercise program for cardiovascular risk
This study tests a new digital tool that helps clinicians prescribe personalized exercise plans to patients with cardiovascular risk factors like high blood pressure, diabetes, or obesity. Participation involves using the tool and following an exercise plan for a few months to see if it improves health.
Farmington, ConnecticutAges 18–64 - NCT06297291Recruiting
Blood pressure study after kidney nerve treatment
This study looks at how well a procedure that uses sound waves to calm kidney nerves (renal denervation) lowers blood pressure over time. It may help people whose blood pressure stays high despite taking medication.
Long Beach, CaliforniaAges 18 years+ - NCT06819878RecruitingPhase 3
Afimkibart for moderate to severe Crohn's disease
This study tests an experimental drug called afimkibart for people with moderate to severe Crohn's disease who haven't responded well to other treatments. The goal is to see if the drug can help control symptoms and reduce inflammation over time.
Dothan, AlabamaAges 16–80 - NCT07378644RecruitingPhase 2/Phase 3
Testing SKY-0515 for Huntington's disease
This trial tests a new drug called SKY-0515 in people with Huntington's disease. The goal is to see if it can safely improve symptoms or slow the disease down.
Englewood, ColoradoAges 25 years+ - NCT06126224RecruitingPhase 3
Testing KarXT for Alzheimer's-related psychosis
This clinical trial tests an investigational oral medication called KarXT for treating psychosis (hallucinations or delusions) in people with Alzheimer's disease. The study aims to see if the drug can safely reduce these symptoms.
Chandler, ArizonaAges 55–90 - NCT05152394RecruitingPhase 1
Testing cord stem cell exosome treatment for Parkinson’s safety
This Phase 1 study tests whether a treatment made from donated umbilical cord “exosomes” is safe in people with Parkinson’s disease. It mainly looks at side effects and safety, and could help guide future treatments if it proves tolerable.
Naples, FloridaAges Any age - NCT05980949RecruitingPhase 3
Long-term safety study of KarXT for Alzheimer's psychosis
This trial tests the long-term safety of an investigational drug called KarXT for people with psychosis caused by Alzheimer's disease. It is for those who have already completed a previous KarXT study and want to continue treatment.
Homewood, AlabamaAges 55–90 - NCT06948110Recruiting
Searching for genes linked to autoimmune diseases
This study looks for genes that may be linked to autoimmune diseases by comparing the DNA of people with these conditions to healthy family members or volunteers. If you have an autoimmune disease or are a healthy person interested in helping research, this study may help scientists understand why these diseases run in families.
Bethesda, MarylandAges 18–115 - NCT07587658RecruitingPhase 4
Dupilumab after a severe COPD flare-up
This study tests whether adding the drug dupilumab to usual hospital care for a severe COPD flare-up helps patients recover better than usual care alone. It is for adults with a specific type of inflammation in their blood, and may reduce the chance of future flare-ups.
Mullica Hill, New JerseyAges 40 years+ - NCT07867184Enrolling by invitation
Firefighter lung health study
This study looks at how firefighting affects your lungs over time. By tracking your health and exposures, researchers hope to find ways to prevent lung problems in firefighters.
Bethesda, MarylandAges 18–65
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,353 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.