Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,506 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07636811RecruitingPhase 2
Mivelsiran for Early Alzheimer's in Down Syndrome
This trial tests a new drug called mivelsiran designed to slow early-stage Alzheimer's disease in adults with Down syndrome. The drug works by targeting amyloid, a protein that builds up in the brain and causes cognitive decline.
Maitland, FloridaAges 40–55 - NCT03854318Recruiting
Study of families with suspected RUNX1 gene changes
This study follows people who have a known or suspected RUNX1 gene variant linked to FPDMM-like features. It may help improve understanding of the gene, and participants may contribute samples that researchers use for genetic testing and research.
Bethesda, MarylandAges 1 day–100 years - NCT07256249Recruiting
Registry studying a drug-coated balloon for coronary artery disease
This trial is tracking the long-term safety and effectiveness of a sirolimus-eluting balloon (Selution SLR) in people with coronary artery disease. It aims to see how well this device works when used to open blocked arteries in real-world medical practice.
AmadoraAges 18 years+ - NCT05847894Recruiting
AI eye scans to help diagnose lung breathing problems
This trial tests an artificial intelligence (AI) tool that uses eye images to help doctors diagnose breathing or lung-related conditions. If you have a lung/breathing problem and can do both eye and lung checkups, it may support faster or more accurate diagnosis.
Guangzhou, GuangdongAges Any age - NCT07262983RecruitingPhase 1
Baricitinib for Job syndrome with lupus or eczema
This study tests if baricitinib, a pill that changes how your immune system works, is safe and tolerable for people with Job syndrome who also have lupus-like disease or severe eczema. It might offer a new treatment option for these skin and immune problems.
Bethesda, MarylandAges 12–120 - NCT06297291Recruiting
Long-term safety study for a kidney nerve treatment
This study tests a device that uses ultrasound to calm overactive kidney nerves, which may help lower blood pressure. It is for people with high blood pressure that is hard to control with medication.
Long Beach, CaliforniaAges 18 years+ - NCT07758114Recruiting
Prenatal education on environmental exposures
This study provides education about everyday environmental exposures during pregnancy. It aims to help women make safer choices for their health and their baby's health.
Galveston, TexasAges 18 years+ - NCT05638867RecruitingPhase 4
Blood thinner choice guided by risk score for heart attack patients
This trial is testing whether a newer type of blood thinner (called a NOAC) can be used safely right after a heart attack or related event, in addition to the standard two antiplatelet medicines. It focuses on patients who have higher risk signs, like elevated D-dimer levels or a higher PARIS risk score, to see if this approach is safe and effective at preventing future heart problems.
Beijing, Beijing MunicipalityAges 18–75 - NCT07758816Recruiting
Better treatments for Gaucher disease with lung or bone problems
This study looks at how standard treatments for Gaucher disease affect lung problems, bone damage, and parkinson-like symptoms. It aims to find better ways to treat these complications and improve quality of life.
New Haven, ConnecticutAges 3 months–75 years - NCT07757178Recruiting
Dementia lived experiences study
This study explores the personal stories and experiences of people with dementia, their families, and caregivers to help improve care and support. Participation involves sharing your experiences in interviews or other tasks.
Nottingham, EnglandAges 18–99 - NCT07105670Recruiting
Replacing high-protein foods in chronic kidney disease
This study looks at how replacing high-protein foods affects people with chronic kidney disease. If you join, you will eat a carefully controlled diet to help researchers understand if changing your protein intake can improve your kidney health.
West Lafayette, IndianaAges 40–70 - NCT03571373Recruiting
Study of new childhood IBD and tracking safety
This trial collects information from children who are newly diagnosed with inflammatory bowel disease (IBD) and follows them to understand safety in real life. It may help doctors improve early diagnosis and treatment planning for kids with IBD.
RotterdamAges birth–19 years - NCT07059507Recruiting
Thyroid cancer in Graves' disease patients having thyroid surgery
This study looks at how often thyroid cancer is found by accident in people with Graves' disease who have their thyroid removed. It helps doctors understand who might be at higher risk so they can plan better care.
Minya, Minya GovernorateAges 18–75 - NCT07270809Recruiting
Chronic liver disease with organ failure: early outcomes study
This study follows patients with chronic liver disease who are hospitalized non-electively for organ failure, to understand the course of illness and outcomes over six months. It may help doctors improve care for similar patients.
New Delhi, National Capital Territory of DelhiAges 18–70 - NCT07041099RecruitingPhase 1
Study of CLN-978 for Sjögren's disease
This trial tests an experimental drug called CLN-978, given as a shot under the skin, that helps your immune system target and destroy disease-causing B cells. It's for people with moderate to severe Sjögren's disease who haven't had success with other treatments.
Orlando, FloridaAges 18 years+ - NCT05705414RecruitingEarly Phase 1
Amino acid supplement during dialysis to improve energy in kidney disease
This early-stage study tests whether taking amino acids during hemodialysis can help people with end-stage kidney disease feel better and maintain strength. It may help by supporting nutrition during dialysis, but it’s mainly meant to gather early safety and benefit information.
San Antonio, TexasAges 18–64 - NCT07722546RecruitingPhase 2
Felzartamab for Graves' disease in adults
This study tests an investigational drug called felzartamab to see if it can help control thyroid function in adults with Graves' disease. It may offer a new option if you are still having symptoms despite anti-thyroid medication.
Dallas, TexasAges 18–75 - NCT07758660Enrolling by invitationPhase 2
Brain scan study for Alzheimer's research
This study uses brain scans (PET) to look at changes in the brain that may be related to memory problems or Alzheimer's disease. It aims to improve understanding of the disease and may help develop better treatments.
New York, New YorkAges 50 years+ - NCT06986070RecruitingPhase 1
Stem cell therapy for mild to moderate COPD
This study tests whether a new type of stem cell (SMS cells) can help people with mild or moderate COPD caused by smoking or pollution. You will receive the treatment by inhalation and be followed to see if your breathing improves.
Melbourne, VictoriaAges 39–69 - NCT07737717RecruitingPhase 1
Testing an mRNA Ebola-Bundibugyo vaccine in healthy adults
This study tests a new mRNA vaccine (mRNA-1469) to prevent Ebola-Bundibugyo virus disease. It is for healthy adults to see if the vaccine is safe and produces an immune response.
Halifax, Nova ScotiaAges 18–65 - NCT07750535Recruiting
Liver fat and scarring in wheat-sensitive patients
This study looks at whether people with non-celiac wheat sensitivity or other digestive conditions have more fat in their liver or liver scarring. It aims to understand if wheat-related issues are linked to liver health.
Palermo, PalermoAges 18–65 - NCT07011732RecruitingPhase 3
Testing a drug for Alzheimer's-related agitation
This study tests an experimental drug (KarXT) to see if it safely reduces agitation in people with Alzheimer's disease. It may help if you or your loved one experiences restlessness, aggression, or irritability related to Alzheimer's.
Scottsdale, ArizonaAges 55–90 - NCT07397884Recruiting
Bone loss and stress markers in implant gum disease
This study looks at markers of bone damage and stress in people with gum disease around dental implants (peri-implantitis). It aims to understand how the body responds, which could help improve treatment.
Keçiören, AnkaraAges 18–65 - NCT07326709RecruitingPhase 3
Votoplam for Huntington's disease: a Phase 3 study
This study tests an investigational drug called Votoplam for people with Huntington's disease. It aims to see if the drug can slow progression of symptoms like movement and thinking problems.
La Jolla, CaliforniaAges 21–70
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,506 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.