Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,506 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04960566Enrolling by invitation
Behavior therapy for reflux symptoms tied to stress responses
This study tests a behavioral approach for people with GERD whose reflux symptoms keep coming back even after they tried an acid-blocking medicine (a PPI). It aims to help by targeting stress-related body responses that may worsen symptoms.
Chicago, IllinoisAges 18–80 - NCT04930289Enrolling by invitation
Lung transplant registry for better donor lung preservation
This study builds a worldwide database to track and improve how donor lungs are preserved before transplant. Your information may help doctors choose and manage donor lungs more effectively.
Phoenix, ArizonaAges Any age - NCT04905238Enrolling by invitation
Sleep apnea study linking breathing markers to memory changes
This trial looks at how severe sleep apnea breathing patterns relate to body “biomarkers” linked to Alzheimer’s disease, using blood or other measures. It may help researchers understand whether sleep apnea is connected to memory and brain health—and who might benefit most from better sleep care.
Palma, Balearic IslandsAges 18–65 - NCT04816773Enrolling by invitation
Long-term follow-up for specific knee replacement parts
This study follows people for up to 10 years after a knee replacement done with specific manufacturer parts. It helps the company and doctors understand how well these knee implants work and whether they cause any long-term problems.
Fremont, CaliforniaAges 21 years+ - NCT04809688Enrolling by invitation
Study how berries affect metabolism and gut bacteria
This study looks at whether eating Saskatoon berries changes how your body uses energy (metabolism) and how your gut bacteria behave. It’s done in healthy people and may help researchers understand how foods could support overall health.
Winnipeg, ManitobaAges 18–75 - NCT04798430Enrolling by invitationPhase 3
Study drug follow-up for LDL reduction in high-risk cholesterol patients
This Phase 3 study looks at the long-term safety and benefit of OLE LIB003 for people with very high cholesterol or heart disease risk who still need lower LDL (“bad cholesterol”). It’s likely a continuation study for participants who already did earlier LIB003 Phase 3 trials.
Evanston, IllinoisAges 10 years+ - NCT04786223Enrolling by invitationPhase 2
Testing an anti-inflammatory PET imaging treatment in memory loss
This Phase 2 study tests whether targeting “neuroinflammation” (inflammation in the brain) can help in Alzheimer’s disease and related memory disorders. You may help researchers by doing several brain scans (including a special PET/CT scan) along with MRI and amyloid imaging to understand what’s happening in the brain.
Rochester, MinnesotaAges 60 years+ - NCT04689854Enrolling by invitation
Cervical spine surgery implant study for neck disc problems
This trial studies specific neck (cervical) spine implants used during surgery for degenerative disc disease or neck instability, along with a particular kind of bone grafting and supporting hardware. It may help patients by testing whether these devices and the planned fusion approach work safely and effectively in real-world surgery.
Orange, CaliforniaAges 18 years+ - NCT04681781Enrolling by invitation
Remote study of SLC13A5 deficiency history
This study follows people with SLC13A5 deficiency to better understand how the condition changes over time, using surveys and clinical check-ins done remotely. If you (or your child) have this genetic condition, it may help researchers learn what symptoms to expect and how to track them.
Palo Alto, CaliforniaAges Any age - NCT04680130Enrolling by invitation
Study of brain, genetics, and clinical symptoms in neurodegenerative illness
This study looks at how your symptoms, brain imaging (MRI), and genetic factors relate to neurodegenerative conditions. It may help researchers better understand what causes these illnesses and how to classify them.
Rochester, MinnesotaAges 21 years+ - NCT04677699Enrolling by invitation
Testing blood for signs of celiac disease and diabetes
This study screens children’s blood to look for signs of celiac disease and type 1 diabetes. It may help doctors understand who is developing these conditions early.
Seattle, WashingtonAges 1 day–7 years - NCT04676100Enrolling by invitation
International registry for cardiac rehabilitation programs
This study collects information about cardiac rehabilitation (CR) programs in lower-resource areas. It helps improve how CR is delivered and understood, especially where healthcare resources and awareness are limited.
DohaAges 18 years+ - NCT04633603Enrolling by invitation
Study of attitudes toward fever and fever care changes
This study looks at how people think about fever and how fever care works in the healthcare system. You may be asked to record details of fever episodes at home or in outpatient care to help researchers understand real-world fever management.
PécsAges Up to 100 years - NCT04605263Enrolling by invitation
Deep brain stimulation for Parkinson’s walking and falls
This study tests a brain surgery treatment (deep brain stimulation) to help improve gait problems such as freezing of walking, gait instability, or falls in people with Parkinson’s disease. It may help people whose walking symptoms are not well controlled by levodopa (a common Parkinson’s medicine).
Phoenix, ArizonaAges 18–75 - NCT04599192Enrolling by invitation
Test heart procedure planning in women using pressure measurements
This trial compares two strategies for deciding which heart blockages to treat, using special pressure and blood-flow measurements during a heart procedure. It may help doctors choose more accurate treatment by tailoring the plan to each person’s heart blood flow.
New Haven, ConnecticutAges 18 years+ - NCT04565704Enrolling by invitation
Imaging checks on biopsy samples during routine scopes
This study uses special optical imaging during routine upper or lower endoscopy to look at biopsy tissue and compare what the images show with standard lab microscope results. It may help improve how doctors spot abnormal tissue during procedures.
Boston, MassachusettsAges 18 years+ - NCT04444362Enrolling by invitation
Probacine to protect organs after cardiovascular surgery
This study tests whether a medicine called Probacine can help protect your gut and organs after cardiovascular surgery. If you qualify, you may be asked to take part and follow the study plan to see if complications are reduced.
Beijing, Beijing MunicipalityAges 18–90 - NCT04432623Enrolling by invitationPhase 1/Phase 2
Test drug for adults with beta thalassemia intermedia
This trial studies an investigational medicine in adults with beta thalassemia intermedia (including non-transfusion dependent thalassemia). The goal is to see how well the treatment works and how safe it is for people whose hemoglobin runs in a certain range.
Oakland, CaliforniaAges 18 years+ - NCT04418830Enrolling by invitation
Study of a spine cage implant for degenerative back problems
This trial studies how well specific lumbar (lower back) implant “cages” help fuse vertebrae in people with degenerative disc disease, spinal slippage, narrowing, curvature, or forward-bending deformity. It may help by testing an approach to improve stability and reduce symptoms after surgery.
La Jolla, CaliforniaAges 18 years+ - NCT04417023Enrolling by invitation
Study for people with neuromuscular diseases
This study is for people (or their close family members) who have a neuromuscular disease, such as motor neuron disease, neuropathies, nerve-to-muscle signaling problems, or muscle diseases. It aims to better understand these conditions and how to move from lab findings to care for patients.
Ottawa, OntarioAges 18 years+ - NCT04364295Enrolling by invitation
Patients who used SeaSpine products join a global registry
This registry collects information from people who have been treated with at least one SeaSpine product and had standard imaging and symptom surveys before and after surgery. It helps doctors understand outcomes over time and can support future improvements in care.
Durango, ColoradoAges Any age - NCT04306380Enrolling by invitation
TIF patient registry for people treated at Indiana University
This study keeps information on people who already had a TIF procedure at Indiana University. It helps researchers learn from past treatments and may improve future care.
Indianapolis, IndianaAges 13 years+ - NCT04279496Enrolling by invitation
CT heart scan registry to track outcomes over time
This is a research registry that follows people who are already getting a CT scan of their heart arteries for medical reasons. It aims to better understand how these scans relate to future heart outcomes, while collecting follow-up health information.
Charlottesville, VirginiaAges 18 years+ - NCT04240665Enrolling by invitation
Test a digital notebook for memory problems
This study tests a digital “memory notebook” to help people who have early memory concerns keep track and report changes over time. It may be useful if you’re having mild memory issues and can complete surveys with a study partner.
Sacramento, CaliforniaAges 60 years+
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,506 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.