Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,506 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04240119Enrolling by invitation
Study blood vessel growth markers in certain brain artery narrowing
This study looks at “angiogenic markers,” which are blood measures that may reflect how blood vessels grow, in people with significant narrowing of a brain artery. It aims to better understand these changes and how they relate to cerebrovascular disease.
Ages 18 years+ - NCT04204135Enrolling by invitation
Tracking hip flexor weakness after specific spine surgeries
This trial follows how hip flexor strength changes after two types of lower-back surgeries (ALIF or LLIF). It may help doctors better predict and prevent weakness in the hip and leg after surgery.
Chicago, IllinoisAges Up to 65 years - NCT04147559Enrolling by invitation
Long-term follow-up for a specific hip replacement stem
This study checks how well a particular hip replacement stem (the PROFEMUR Preserve Classic Femoral Stem) and matching parts keep working over many years. You may be invited if you had that exact hip replacement combination and can return for long-term checkups.
Scottsdale, ArizonaAges 21 years+ - NCT04141605Enrolling by invitation
Heart transplant candidates matched for better heart preservation
This study creates a worldwide registry and information database to help improve how donor hearts are preserved for transplant. If you are a heart transplant candidate, your details may be recorded to see what matching and preservation approaches work best.
Stanford, CaliforniaAges Any age - NCT04104659Enrolling by invitation
Tau PET scan study to map brain changes in Alzheimer’s
This study tests a PET scan “tracer” medicine called [18F]MK-6240 to see how tau protein changes show up in the brain. It may help researchers measure disease-related brain changes in people with normal thinking or mild dementia.
St Louis, MissouriAges 18 years+ - NCT04100486Enrolling by invitation
Testing a noninvasive device to measure your body signals
This study uses a noninvasive bioelectronic device to record your body’s automatic (involuntary) signals. The goal is to see how well the device can analyze these signals and how your body responds in a controlled setting.
Manhasset, New YorkAges 18–60 - NCT04066608Enrolling by invitation
Screening for advanced liver scarring in people with HIV
This study looks at how common advanced liver scarring (advanced fibrosis) is in people living with HIV. It may help doctors better understand liver risk in everyday care and guide future prevention.
MainzAges 18 years+ - NCT04065516Enrolling by invitation
Test for reflux treatment after POEM for achalasia
This study looks at a specific treatment (“ARAT”) to help people who develop acid reflux after a procedure called POEM for achalasia. It may help reduce reflux symptoms and abnormal acid levels in the stomach/esophagus after the original procedure.
Mexico City, Mexico CityAges 18 years+ - NCT04064008Enrolling by invitation
Long-term follow-up for a specific hip revision stem
This study follows people who had a hip replacement redone (revision) because of bone healing problems or hardware removal, using a specific revision femoral stem. It checks how the stem does over time and follows up for up to 10 years after surgery.
OtwockAges Any age - NCT04016181Enrolling by invitation
Study to categorize lung fibrosis types at a clinic
This study enrolls people who have interstitial lung disease and are seen at the Edinburgh lung fibrosis clinic. It aims to sort different underlying “types” of lung fibrosis so doctors can better understand and potentially guide care.
Ages 18–99 - NCT04008173Enrolling by invitation
Survey study of acute heart attack symptoms
This study collects information about symptoms and experiences during acute coronary syndromes, which are sudden, serious heart events like heart attacks or unstable angina. It may help researchers understand patterns of care and symptoms to improve future treatment and support.
Bologna, BolognaAges 18 years+ - NCT04003311Enrolling by invitation
Follow-up for specific shoulder implant types and surgery
This study checks outcomes in people who already received certain Zimmer Biomet shoulder implant components using the correct surgical technique. It may help improve how these specific implants are used and monitored after surgery.
Boise, IdahoAges 18 years+ - NCT04003272Enrolling by invitation
Reverse shoulder implant study for severely damaged rotator cuff
This trial studies a specialized reverse shoulder implant system for people whose rotator cuff is badly damaged or who had a prior shoulder replacement that failed. It aims to reduce pain and improve function by improving how your shoulder works, especially when the rotator cuff can’t do its job.
Louisville, KentuckyAges 18 years+ - NCT03976622Enrolling by invitation
Inflammation study in vitiligo and other skin conditions
This study looks at inflammation in people with vitiligo, psoriasis, atopic dermatitis, or alopecia areata. It aims to understand how these conditions compare, which may lead to better treatments.
Bordeaux, BordeauxAges 18–75 - NCT03853772Enrolling by invitation
Heartburn registry for long-term symptom and care follow-up
This registry enrolls people with GERD (chronic heartburn/reflux) to track symptoms and treatments over time for up to 5 years. It may help researchers understand what works best in everyday care, and you’ll be asked to complete check-in surveys.
Orange, CaliforniaAges 18 years+ - NCT03815656Enrolling by invitation
Closed-loop deep brain stimulation for Parkinson’s medication side effects
This study tests a “smart,” closed-loop deep brain stimulation (DBS) system that adjusts stimulation based on your brain signals. It’s designed for people with Parkinson’s who get troubling medication side effects, with the hope of improving symptoms more smoothly.
Durham, North CarolinaAges 18–75 - NCT03756649Enrolling by invitation
IBD biobank study for adults and young adults
This study collects and stores information and samples from people with inflammatory bowel disease (IBD) to help researchers learn more and improve care. Your participation mainly helps build a “biobank,” which can support future studies.
Rochester, MinnesotaAges 18–85 - NCT03687710Enrolling by invitation
Alzheimer’s registry for people with memory concerns or risk
This is a research registry that helps doctors compare how different memory and Alzheimer’s risk groups change over time. It may help researchers learn which people are more likely to develop Alzheimer’s and how to better track early changes.
New York, New YorkAges 18–99 - NCT03649490Enrolling by invitation
Testing new spinal implant materials for XLIF fusion
This study compares different advanced materials used in a specific spinal fusion surgery (XLIF). It aims to see which implant material helps the bone fuse well and safely over time.
Hartford, ConnecticutAges 18–80 - NCT03576573Enrolling by invitation
Follow-up study for specific hip replacement components
This study checks outcomes after a specific type of hip surgery using specific brand parts. You may help by sharing follow-up visit information so the sponsor can confirm the components work as expected in everyday patients.
BuxtehudeAges 21 years+ - NCT03492372Enrolling by invitation
Study of molecular changes in removed spinal tissue
This study looks at what’s happening at the molecular level in spinal tissue that is normally removed during surgery. It may help researchers better understand spinal conditions and improve future treatments, using tissue provided as part of routine care.
Rochester, MinnesotaAges 1–80 - NCT03474237Enrolling by invitation
Study following people newly diagnosed with adrenal conditions
This study follows adults with a new adrenal diagnosis to learn how adrenal diseases behave over time. It may help doctors better understand these conditions and improve future care.
SeoulAges 19 years+ - NCT03407833Enrolling by invitation
Study changes in the body after weight, gut, or liver treatment
This study looks at how the body’s insulin-sensitivity (how well your body uses sugar/insulin) and organ function change after certain medical procedures. It may help researchers understand why some people improve after surgery or liver transplant and guide future care.
Nashville, TennesseeAges 18 years+ - NCT03385876Enrolling by invitation
Rapid whole genome sequencing for children with suspected genetic illness
This study quickly reads a child’s DNA using whole genome sequencing to look for genetic causes of symptoms. It may help families and doctors better understand an underlying genetic condition and guide medical care.
San Diego, CaliforniaAges Any age
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,506 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.