Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06879444Enrolling by invitation
Core strength and pelvic floor in Sjogren's
This study looks at how core stability and pelvic floor muscles work in people with primary Sjogren's syndrome. If you have this condition, the results may help doctors understand changes in muscle function.
Denizli, DenizliAges 18–65 - NCT06871293Recruiting
Long Covid recovery: rehab with coaching
This study tests a program of rehab exercises and memory/thinking activities, along with coaching messages, to help people with Long Covid feel better and function in daily life. You may qualify if you had Covid, have high blood pressure or diabetes, and still have symptoms like fatigue or trouble thinking for at least 4 weeks.
Bogotá, Bogotá DCAges 18–80 - NCT06876415Recruiting
Comparing two ways to wean patients off ECMO
This study compares two methods for removing patients from a breathing machine called ECMO. It aims to find which approach works better and is safer.
LyonAges 18 years+ - NCT06859424RecruitingPhase 2
Testing a new GVHD prevention method after donor stem cell transplant
This trial tests a new way to prevent graft-versus-host disease (a common side effect of stem cell transplant) using a drug called cyclophosphamide after transplant. It is for adults with certain blood cancers who need a transplant from a partially matched unrelated donor.
Birmingham, AlabamaAges 18–66 - NCT06859918Recruiting
Social skills program for adults with autism
This study tests a social and emotional program called TUNE In 3.0 for adults with autism. It is designed to help improve social connections and emotional well-being.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06857929Recruiting
Nutrition study for metabolic syndrome
This study tests whether a personalized nutrition plan can improve health and lower the risk of chronic diseases like diabetes and heart disease in middle-aged adults with metabolic syndrome.
Madrid, MadridAges 30–50 - NCT06865885RecruitingPhase 4
Lowering cholesterol with inclisiran in people on many medications
This study tests a new injectable medicine called inclisiran for people who are already on many medications and have high cholesterol. It is designed for those who cannot lower their cholesterol enough with statins, especially if they have diabetes or other heart risks.
La Jolla, CaliforniaAges 18–85 - NCT06863402RecruitingPhase 2
Study of two drugs for Richter transformation lymphoma
This study tests a combination of two oral drugs (nemtabrutinib and pembrolizumab) for people with Richter transformation, an aggressive lymphoma that develops from chronic lymphocytic leukemia. It may be an option if standard chemotherapy is not suitable or if prior treatment has stopped working.
Buffalo, New YorkAges 18 years+ - NCT06865222Recruiting
Magnetic brain stimulation for lingering COVID symptoms
This study tests whether a special type of magnetic stimulation (called TMS) can help with lingering symptoms after COVID-19, such as loss of smell, ringing in the ears, or fatigue. The treatment is safe and non-invasive, using a magnet placed near your head.
Rochester, MinnesotaAges 18–65 - NCT06866106Recruiting
Well-being in IBS: A phone program for strengths and happiness
This study tests a program that helps people with IBS focus on their strengths and happiness through phone sessions. It aims to see if this approach can improve well-being and manage IBS symptoms.
Boston, MassachusettsAges 18 years+ - NCT06863207Recruiting
Testing a new treatment for teens with stomach and nerve problems
This study tests whether a personalized nerve stimulation treatment can help teens with cyclic vomiting syndrome or functional dyspepsia who also have symptoms of autonomic dysfunction, like dizziness, fatigue, or heart palpitations when standing.
Milwaukee, WisconsinAges 11–18 - NCT06062212Recruiting
Effects of lung pressure on recovery in severe ARDS on ECMO
This trial looks at how changes in lung pressure during breathing might affect recovery in patients with severe ARDS who are on a heart-lung bypass machine (ECMO). It could help doctors improve treatment for people with this serious lung condition.
Beijing, Beijing MunicipalityAges 18–75 - NCT06851091Recruiting
Fibromyalgia study on pain sensitivity and balance
This study looks at how fibromyalgia affects your sensitivity to pain and your sense of balance. It may help find better ways to treat these symptoms.
Istanbul, ÜsküdarAges 18–65 - NCT06854627Recruiting
Comparing two ways of lying face down for ARDS patients
This study compares lying face down continuously for a long time versus lying face down for shorter periods each day. It is for patients with moderate to severe ARDS (a serious lung condition) who are on a breathing machine. The goal is to see which approach helps the lungs recover better.
Buenos AiresAges 18 years+ - NCT06847360Recruiting
Home-based ear stimulation for IBS pain
This trial tests a gentle, non-invasive ear stimulation device (taVNS) used at home to reduce pain from Irritable Bowel Syndrome (IBS). It might help if you have moderate pain most days.
New Haven, ConnecticutAges 18–29 - NCT04987775RecruitingEarly Phase 1
Study of NAC for Gulf War illness in veterans
This early-stage study tests the treatment called NAC to understand how it may work in veterans with Gulf War illness–related symptoms like fatigue and brain/mood changes. It also looks at “mechanisms,” meaning what’s happening in the body and brain while you’re in the study.
Palo Alto, CaliforniaAges 47–70 - NCT06270771Recruiting
Using a wearable ring to monitor MDS patients at home
This study tests if people with MDS can comfortably wear the OURA ring (a smart ring) at home to track their health. The goal is to see if this is a useful way to monitor symptoms and well-being between doctor visits.
Toronto, OntarioAges 18 years+ - NCT06842316Recruiting
Study on cannabis-like compounds for inflammatory arthritis
This trial tests whether plant-based compounds similar to cannabis (called phytocannabinoids) can help calm inflammation and improve immune function in people with certain types of arthritis or autoimmune diseases like lupus or Sjögren's disease. It aims to offer a new way to treat these conditions without the 'high' of marijuana.
OrléansAges 18 years+ - NCT06845826Recruiting
Quick Troponin Test in the ER for Chest Pain
This trial is checking a quick bedside blood test (troponin) for people who come to the emergency room with chest pain. It aims to see if the test can help doctors decide faster if you are having a heart attack.
Leuven, Vlaams-BrabantAges 18–75 - NCT06845735Recruiting
Comparing two types of stitches for hip surgery closure
This trial compares two types of stitches (absorbable vs. non-absorbable) used to close the hip capsule during hip arthroscopy, to see if one leads to better recovery. If you need hip arthroscopy for a hip problem, you may be able to join.
Columbia, MissouriAges 18 years+ - NCT06843096Enrolling by invitation
Special mammogram for finding breast cancer when origin is unknown
This trial uses a special mammogram with contrast dye to look for breast cancer in people who have cancer that started somewhere unknown (called Cancer of Unknown Primary). It may help find if the breast is the source, which could guide treatment.
RomeAges 18 years+ - NCT06837038Enrolling by invitation
Rhythmic beats to improve walking after stroke or Parkinson's
This trial tests whether listening to rhythmic music while walking can improve gait problems caused by stroke, Parkinson's disease, or other parkinsonism conditions. It is designed for people who can walk on their own but have an uneven or slow pace.
Beijing, Beijing MunicipalityAges 50–80 - NCT06845865Recruiting
Gut barrier test in ICU patients with organ failure
This study looks at how the gut barrier works in people with severe infections that cause organ failure. It measures intestinal permeability using a simple test, to see if a 'leaky gut' contributes to how sick patients get.
VincennesAges 18 years+ - NCT05957549Recruiting
Tracking early sound perception in young children
This study uses special brain-monitoring tools (fNIRS and EEG) to look at how preschool-aged children process sounds. It may help researchers understand early sound perception differences, especially in children with Fragile X Syndrome.
Cincinnati, OhioAges 2–4
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.