Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06916520RecruitingPhase 4
Reduced dose prasugrel alone after stent placement
This trial tests if a lower dose of prasugrel, taken alone (without aspirin), is safe and works well for people who have had a stent placed for chest pain or a heart attack. It might be an option for those who need to simplify their medication routine.
AmsterdamAges 18 years+ - NCT06914245Recruiting
Personalized help for bowel symptoms after rectal cancer treatment
This trial studies how to improve bowel symptoms in people treated for rectal cancer. It tests personalized care plans and looks at different factors that may contribute to bowel problems after surgery or a watch-and-wait approach.
Leuven, Vlaams-BrabantAges 18 years+ - NCT06901245RecruitingPhase 4
Tirzepatide for young adults with obesity
This study tests the diabetes/weight-loss drug tirzepatide (Mounjaro) in young adults aged 18–26 who have obesity and either Prader-Willi syndrome, hypothalamic obesity, or general obesity. It looks at whether a weekly injection can help with weight management.
Saint Paul, MinnesotaAges 18–26 - NCT06903962Recruiting
Mind-body program for chronic arm or hand pain
This trial tests whether a mind-body program can help people with long-term pain in their upper arm, forearm, or hand that is not caused by a clear physical injury. It focuses on retraining how your brain responds to pain triggers.
Boston, MassachusettsAges 18–60 - NCT06906276Recruiting
Brain activity during walking in atypical Parkinson's
This study looks at brain activity while walking in people with atypical Parkinsonian syndromes like PSP or MSA. It may help understand how these conditions affect walking and balance.
Solna, SolnaAges Any age - NCT06904482RecruitingPhase 2
Stem cell transplant with half-matched donor and cord blood
This trial tests a new way to do a stem cell transplant for people with hard-to-treat blood cancers. It combines a half-matched family donor (haploidentical) with a cord blood unit to help the transplant work better.
Cleveland, OhioAges 18 years+ - NCT06910436Recruiting
AI timing and outcomes in heart attack study
This trial uses artificial intelligence to analyze ECG results and timing in patients with a type of heart attack called Non-STEMI (where the artery is narrowed but not fully blocked). The goal is to see if AI can help predict damage and outcomes, which could lead to better care.
Bolzano, BZAges 18 years+ - NCT06418217Recruiting
Exercise and education for lateral hip pain
This study tests whether exercise and patient education can help people with long-term lateral hip pain (pain on the outside of the hip). If you've had hip pain for over 6 months and an MRI confirms the cause, you may be able to join.
Horsens, HorsensAges 18–75 - NCT04467671RecruitingPhase 2
Tested new blood vessel graft for a heart surgery
This trial studies whether a newer “tissue-engineered” blood vessel graft is safe and works well in children who need a specific heart surgery connection outside the heart. It may help by offering a new type of graft, but your team will screen for size and medical factors first.
Columbus, OhioAges Any age - NCT06892275Recruiting
Helping high-risk women decide about breast MRI
This study tests a decision aid to help women at high risk for breast cancer decide whether to get a screening MRI. It is designed for Black and Latina women who have had a normal mammogram in the past year.
Washington D.C., District of ColumbiaAges 18–74 - NCT06896448Recruiting
Sleep apnea screening for head and neck cancer patients
This study tests a smartphone app (Apneal) to screen for sleep apnea in people who are being checked for head and neck cancer. It aims to find sleep problems early so they can be treated.
Caen, FranceAges 18 years+ - NCT06892041Recruiting
MRI study for jaw muscle pain
This trial uses a special MRI scan to measure jaw muscle pain. It aims to better understand this condition and may help improve future treatments.
New York, New YorkAges 18–65 - NCT06895473RecruitingPhase 2
Spinal injection to prevent nerve side effects from CAR-T therapy
This trial tests if a spinal injection of three common chemotherapy drugs can reduce or prevent serious brain and nerve side effects in people receiving CAR-T cell therapy for cancer.
Portland, OregonAges 18 years+ - NCT06898996Recruiting
Stool test study for Lynch syndrome colon screening
This trial tests a new stool-based test (FIT) to see if it can help find colon cancer early in people with Lynch syndrome. You will collect stool samples at home and complete surveys before your regular colonoscopy.
Chicago, IllinoisAges 20–80 - NCT06199557RecruitingPhase 1/Phase 2
Gentle drug combo for AML or high-risk MDS
This trial tests a combination of two oral drugs (hydroxyurea and valproic acid, or 6-mercaptopurine and valproic acid) for people with AML or high-risk MDS who are too frail for standard chemotherapy. The goal is to see if this gentler treatment can help control the disease.
Bergen, BergenAges 18 years+ - NCT06566950Recruiting
Blood flow training for leg muscle health in athletes
This study tests a training method that uses light blood flow restriction to improve leg muscle structure. It is for young athletes (ages 15–35) who play high-level sports like martial arts, basketball, soccer, or futsal at least twice a week.
Denpasar, BaliAges 15–35 - NCT04445571Recruiting
Surfactant given with a thin tube or catheter device
This trial tests two ways of giving surfactant (a lung medicine) to very premature babies with respiratory distress syndrome. It may help show which method works better and is safer for helping newborn lungs breathe.
StockholmAges Up to 2 days - NCT06889454Recruiting
Heart and blood vessel changes in women with PCOS after treatment
This trial looks at how the heart's blood vessels and certain markers change in women with PCOS when they drink a sugary solution (OGTT). It checks these markers before treatment starts and again 6 and 12 months after, to help understand cardiovascular risk in PCOS.
ChaïdáriAges 18–45 - NCT06888570Enrolling by invitation
Liver health study for children & young adults with Down syndrome
This study looks at how eating patterns and body composition relate to fatty liver in children and young adults with Trisomy 21 (Down syndrome) or other genetic intellectual disabilities. It may help understand who is at risk and how to prevent liver problems.
Madrid, MadridAges 5–22 - NCT06888024Recruiting
Measuring pelvic vein blood flow with MRI
This study uses MRI scans to measure blood flow in the pelvic veins. It’s for people who either have no vein problems, or have symptoms of a compressed left iliac vein, or already have a stent in that vein. The goal is to learn more about how blood flows in these conditions.
Worcester, MassachusettsAges 18–89 - NCT06889974Recruiting
Timing of kidney treatment in tumor lysis syndrome
This study looks at when to start kidney dialysis for patients in the ICU who develop tumor lysis syndrome (a rapid breakdown of cancer cells after chemotherapy that can harm the kidneys). It aims to find the best timing for this treatment.
AngersAges 18 years+ - NCT06880016Recruiting
Lung ultrasound after surfactant in preterm babies
This study uses lung ultrasound to see how different ways of giving surfactant (a medicine for breathing problems) affect preterm babies born before 32 weeks. It may help doctors choose the best method for your baby.
Konya, KaratayAges 1 day–5 days - NCT06870149Recruiting
Dance program to improve mobility in older adults at risk
This study tests whether a structured dance program (called GERAS DANCE) can help older adults who are frail or at risk of losing mobility. You would attend dance sessions at the YMCA twice a week, and researchers will see if it improves your walking and daily function.
Hamilton, OntarioAges 65–100 - NCT06868979Recruiting
Eye imaging for X-linked disorders
This study uses special eye imaging to look at changes in the brain and eyes of people with creatine transporter deficiency (a condition that affects brain energy) or fragile X syndrome. It aims to find a way to see these brain changes without needing a biopsy or spinal tap.
BronAges 5–60
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.