Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06538558RecruitingPhase 1
Study of tezampanel for opioid withdrawal
This trial tests if tezampanel can help relieve withdrawal symptoms in people with opioid use disorder who are seeking treatment. Participants must already be in an outpatient addiction program.
Indianapolis, IndianaAges 18–65 - NCT06538714Recruiting
Interval training for overweight or obese girls
This study tests whether a special type of exercise (interval training) can improve heart and metabolic health in girls aged 12 to 15 who are overweight or obese. It may help you understand a new way to get and stay healthy.
TunisAges 12–15 - NCT06538779Recruiting
Ultrasound study of median nerve variations in carpal tunnel
This study uses ultrasound to look at the median nerve in the wrist of people with carpal tunnel syndrome. It aims to find common nerve variations that might affect treatment.
Ankara, AnkaraAges 18–65 - NCT06539169Recruiting
Following people with rare diseases over time
This study follows people with rare diseases over time to learn more about how these conditions progress and how they are treated. Joining may help researchers understand your disease better and find better ways to care for others.
Los Altos, CaliforniaAges Any age - NCT06539234Recruiting
Testing angiotensin II for vasoplegic shock
This trial gives a drug called angiotensin II to people in vasoplegic shock (a type of shock where blood vessels stay too relaxed despite other medicines). It tests how the drug affects a kidney-related hormone (renin) and if it can help raise blood pressure.
MariborAges 18 years+ - NCT06539507RecruitingPhase 1
Study of BCX17725 for Netherton syndrome safety
This trial tests a new drug called BCX17725 in people with Netherton syndrome to see if it is safe and how the body handles it. It may help by reducing skin symptoms like redness and scaling.
Palo Alto, CaliforniaAges 12–65 - NCT06541626Recruiting
Study of CNS inflammatory demyelinating diseases
This study follows people with certain inflammatory conditions of the brain and spinal cord (like MS, NMOSD, or MOGAD) to learn more about their disease. If you join, you will help researchers understand these conditions better.
Guangzhou, GuangdongAges 18–65 - NCT06543082RecruitingPhase 4
Study on heart attack patients with antiplatelet and colchicine therapy
This trial is for people who had a heart attack and received a specific type of stent (Orsiro). It tests a combination of a single antiplatelet drug and colchicine to see if it helps prevent future heart problems. Colchicine is a medicine that reduces inflammation and might lower the risk of another heart attack.
Seongnam-si, Gyeonggi-doAges 20–90 - NCT06543381RecruitingPhase 1
Olutasidenib for IDH1-mutated blood cancers after transplant
This trial tests a drug called olutasidenib for people with certain blood cancers (AML, MDS, or CMML) that have a specific IDH1 gene change. The goal is to see if it can help prevent relapse after a donor stem cell transplant.
Duarte, CaliforniaAges 18 years+ - NCT06543667RecruitingPhase 1
Stem cell eye drops for dry eye treatment
This trial tests a new eye drop made from stem cells to see if it can help relieve dry eye symptoms. It is for people with moderate to severe dry eye who haven't had recent eye surgery or used other eye drops.
TehranAges 18–70 - NCT06545448Recruiting
Study of planned angioplasty in stable heart disease
This study looks at whether planned angioplasties (a procedure to open blocked heart arteries) are done appropriately for people with long-term stable heart disease. It aims to help doctors make better decisions for patients like you.
São Paulo, São PauloAges 18 years+ - NCT06545994Recruiting
Studying kisspeptin hormone levels in PCOS pregnancy
This study looks at a hormone called kisspeptin in pregnant women with PCOS. It aims to understand how this hormone changes during pregnancy, which may help improve care for women with PCOS.
Shanghai, Shanghai MunicipalityAges 18–40 - NCT06548607RecruitingEarly Phase 1
CAR-T therapy for autoimmune diseases
This early-phase trial tests a new CAR-T cell therapy that targets CD19 or both CD19 and BCMA to treat several autoimmune diseases like lupus, scleroderma, and vasculitis. It aims to calm the overactive immune system with a single infusion of your own engineered cells.
Bengbu, AnhuiAges 18–70 - NCT06550713RecruitingPhase 1
Testing TQB3455 tablets for blood cancers with IDH2 mutation
This trial tests a new tablet, TQB3455, for people with certain blood cancers (MDS or AML) that have an IDH2 mutation. The goal is to see if the drug can help when other treatments haven't worked or aren't possible.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06551584RecruitingPhase 1
Advanced blood cancer trial with stem cell transplant
This trial tests a new approach for people with advanced blood cancers who are getting a donor stem cell transplant. It aims to improve outcomes by using your own regulatory T cells along with the donor cells.
Palo Alto, CaliforniaAges 18–70 - NCT06551961Recruiting
How two fibers affect your gut health
This study tests how two types of fiber (inulin and methylcellulose) affect your gut when eaten regularly. You'll eat provided meals and have your breath tested to see how your gut breaks down the fiber.
Nottingham, NottinghamshireAges 18–65 - NCT06553339RecruitingPhase 1
A study of HS-10516 for VHL syndrome tumors
This trial tests a new drug called HS-10516 in people with VHL syndrome or advanced kidney cancer. The goal is to see if the drug can shrink tumors and what side effects it might have.
Beijing, Beijing MunicipalityAges 18–80 - NCT06553898RecruitingPhase 1
CAR-T cell therapy for hard-to-treat kidney disease
This trial tests a new CAR-T cell treatment for children and adults with steroid-resistant nephrotic syndrome (SRNS), a kidney condition that doesn't get better with standard medicines. The goal is to see if this therapy can help improve kidney function when other treatments have failed.
Hangzhou, ZhejiangAges 2 years+ - NCT06555237RecruitingPhase 2
MEK inhibitors for heart thickening in RASopathies
This trial tests a targeted drug (MEK inhibitor) to treat thickened heart muscle caused by a group of genetic conditions called RASopathies. It may help improve heart function in people with hypertrophic cardiomyopathy.
WarsawAges 1 day–18 years - NCT06555523Recruiting
Trigger point shots for muscle pain syndrome
This trial tests if injecting trigger points in the neck and shoulder muscles can relieve pain in people with fibromyalgia and chronic myofascial pain syndrome. It may help reduce muscle tightness and improve function.
ElâzığAges 18–65 - NCT06557551Recruiting
Surfactant for preterm babies born before 28 weeks
This trial tests giving surfactant through a thin tube into the windpipe right after birth for babies born before 28 weeks. It aims to help their lungs work better and reduce breathing problems.
Dublin, None SelectedAges Up to 30 minutes - NCT06557993Recruiting
Nerve block injection for myofascial pain syndrome
This study tests a type of nerve block injection (called serratus posterior superior intercostal plane block) guided by ultrasound to see if it helps relieve pain from myofascial pain syndrome. It may be a treatment option for people with MPS who haven't had recent procedures.
IstanbulAges 18–65 - NCT06565520Recruiting
Brain stimulation for kneecap pain
This study tests whether a gentle brain stimulation technique can help improve how your knee moves when you have kneecap pain. It's for people whose kneecap pain has lasted at least 3 months and whose knee tends to cave inward.
Las Vegas, NevadaAges 18–45 - NCT06566066Recruiting
Thyroid hormone resistance patient registry
This study creates a registry for people with thyroid hormone resistance caused by specific genetic mutations. It helps doctors collect data to better understand and treat the condition.
BerlinAges Any age
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,173 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.