Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06834282RecruitingPhase 1
A study of CER-1236 for certain blood cancers
This trial tests an experimental cell therapy called CER-1236 for people with acute myeloid leukemia, myelodysplastic syndrome, or myelofibrosis. It aims to see if it can help treat these cancers.
Sacramento, CaliforniaAges 18–85 - NCT06827262Recruiting
A procedure for vertebrogenic back pain relief
This trial tests a minimally invasive procedure that uses a special device to target and treat nerve-related back pain coming from the vertebrae (the bones in your spine). It may offer lasting relief without more major surgery.
Flagstaff, ArizonaAges 18 years+ - NCT06830655Enrolling by invitation
Climbing performance and body factors study
This study looks at how mobility, balance, and fatigue affect climbing performance. If you are a healthy climber, you may help researchers understand what makes a better climber.
Gdansk, GdańskAges 15–45 - NCT06830226Enrolling by invitation
Domperidone and preterm breast milk nutrients
This study looks at how domperidone, a medicine used to help increase breast milk supply, affects the nutritional content of breast milk from mothers of premature babies. By understanding this, doctors can better support your baby's growth.
LisbonAges Any age - NCT06829901Recruiting
Uterine entry technique in laser surgery for twin-to-twin transfusion syndrome
This study looks at how doctors enter the uterus during laser surgery to treat twin-to-twin transfusion syndrome (TTTS), a condition where blood flow between twins is unequal. The goal is to see if a certain entry method leads to better outcomes for the babies.
Houston, TexasAges 18 years+ - NCT06826807Enrolling by invitation
Lifestyle change study for fatty liver disease
This study tests whether adding a liver stiffness measurement to a lifestyle program helps people with MASLD (a type of fatty liver disease) improve their liver health. It is designed for people who have fatty liver and at least one sign of metabolic syndrome, like high blood pressure or diabetes.
Bangkoknoi, BangkokAges 18–80 - NCT06333990RecruitingPhase 3
Quetiapine for concussion symptoms in veterans
This study tests whether quetiapine (a medication that can help with mood, sleep, and thinking) reduces ongoing concussion symptoms in veterans who had a mild traumatic brain injury (mTBI) at least 6 months ago. You may join if you are already taking at least three medications for your brain or mental health symptoms and have some PTSD symptoms.
Albuquerque, New MexicoAges 18–65 - NCT06820268RecruitingPhase 1
XS-04 for blood cancers that returned after treatment
This study tests a new drug, XS-04, for people with certain blood cancers (like B-cell lymphoma, AML, or MDS) that have come back or not responded to standard treatments. The goal is to see if the drug is safe and can help shrink tumors or control the disease.
BeijingAges 18–75 - NCT06822231Recruiting
High-tech rehab for acute neuromuscular diseases
This study tests a high-tech rehab program using robots and advanced tools to help people recover from acute neuromuscular diseases. It aims to see if this approach improves leg strength and mobility better than standard care.
BariAges 18–80 - NCT06821568Recruiting
Home brain stimulation for memory and walking concerns
This study tests if a gentle brain-stimulation device used at home can help older adults who have both memory worries and slower walking. A study partner will help you use the device.
Roslindale, MassachusettsAges 65–90 - NCT06818994RecruitingPhase 1
Psilocybin therapy for low mood in advanced cancer
This trial tests if a medicine called psilocybin, given with talk therapy, can safely help people with advanced cancer who feel very demoralized. Demoralization is a deep sense of hopelessness or loss of meaning. The goal is to see if this treatment can improve your emotional well-being.
Kingston, OntarioAges 18–70 - NCT06816095Recruiting
Ozone therapy for pelvic pain after gynecological cancer treatment
This study is looking at whether ozone therapy can help relieve chronic pelvic pain caused by gynecological cancer treatments like radiation and chemotherapy. It aims to understand how the treatment works at a molecular level.
Las Palmas, Las PalmasAges 18 years+ - NCT06817980Recruiting
Sense of self and physical activity study
This study looks at how physical activity affects your sense of self in people with schizophrenia, borderline personality disorder, or inner ear disorders. It involves vision tests, exercise, and questionnaires.
StrasbourgAges 18–60 - NCT06657846Recruiting
Quality of life and costs for people with VEXAS
This study looks at how VEXAS syndrome affects your daily life and finances. It aims to understand the challenges you face so doctors can better support you.
AnconaAges 18–99 - NCT06554275Recruiting
CCHS research health hub
This study creates a secure health information hub for people with Congenital Central Hypoventilation Syndrome (CCHS) to help researchers better understand the condition and find new ways to treat it. Being part of this hub may help advance future studies and care options for CCHS.
Chicago, IllinoisAges Any age - NCT06517056Recruiting
3D Knee Assessment for Active Duty Knee Pain
This trial tests a 3D camera device that measures how your knee moves. It may help find the best way to treat your front-of-knee pain and keep you mission-ready.
Honolulu, HawaiiAges 18–50 - NCT06807177Enrolling by invitation
Collagen injections for chronic neck pain
This trial tests if collagen injections into the neck can reduce chronic muscle pain and whether certain blood markers can show how well the treatment works. It may help if you have had neck pain for more than 12 weeks.
WarsawAges 18–65 - NCT06812130Recruiting
Surviving the pediatric intensive care unit
This study looks at how children and their healthy siblings cope after a stay in the pediatric intensive care unit (PICU). It may help doctors and families better understand what support is needed during recovery.
Singapore, SingaporeAges 4 weeks–16 years - NCT06813339RecruitingEarly Phase 1
Testing a new drug in healthy people and those with heart condition
This trial tests a new medicine called UDP-003 in two groups: healthy volunteers and people who had a heart event (acute coronary syndrome) at least a year ago. The goal is to see if the drug is safe and how the body handles it, which could lead to better treatments for heart disease.
Adelaide, South AustraliaAges 18–79 - NCT06810518Recruiting
Studying stool test for digestive disease diagnosis
This trial tests a new stool test to measure calprotectin levels, which could help doctors tell the difference between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). If you have symptoms like stomach pain, diarrhea, or weight loss and are about to have a colonoscopy, you may be able to join.
Miami, FloridaAges 22 years+ - NCT06807983Recruiting
Lung and heart ultrasound for breathing trouble in older adults
This trial tests whether using lung and heart ultrasound (LuCUS) can help emergency doctors better diagnose and treat shortness of breath in patients over 65. It aims to improve care for older adults with severe breathing problems.
ToulouseAges 65 years+ - NCT06815003RecruitingPhase 2
Preventing Graft-Versus-Host Disease After Stem Cell Transplant
This trial tests a combination of three drugs (vedolizumab, cyclophosphamide, and tacrolimus) to prevent graft-versus-host disease, a common complication after a donor stem cell transplant. It is for people with certain blood cancers who are getting a reduced-intensity transplant.
Duarte, CaliforniaAges 18–80 - NCT06805734Recruiting
Tracking health in children with PTEN gene changes
This study follows children and their affected relatives who have a harmful change in the PTEN gene. The goal is to understand the health risks, especially the chance of developing cancer, over time.
MilanAges Up to 17 years - NCT02664831Recruiting
Study of inflammation after cardiac arrest in ICU patients
This trial looks at how the body’s inflammation response behaves after someone has a cardiac arrest and was treated in the ICU. It may help doctors understand which patients could benefit from treatments that target harmful inflammation after resuscitation.
Portland, MaineAges 18 years+
Hear when a new Down Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.