Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06614595Recruiting
Transfusion and quality of life in lower-risk MDS
This study looks at how well transfusions work and how they affect quality of life in people with lower-risk MDS who need regular blood transfusions. The goal is to find what predicts a good transfusion response and to improve care.
Oviedo, Principality of AsturiasAges 18 years+ - NCT06614894RecruitingPhase 2/Phase 3
High dose ambroxol for adults with Sanfilippo syndrome
This trial tests a high dose of a medicine called ambroxol in adults with MPS III (Sanfilippo syndrome). It aims to see if the drug is safe and can help symptoms.
Fairfax, VirginiaAges 18–99 - NCT06614998Recruiting
Early warning screening for hemophagocytic lymphohistiocytosis
This study aims to create an early warning system to identify patients with hemophagocytic lymphohistiocytosis (HLH), a rare but serious immune overreaction. If you have certain infections, autoimmune diseases, or lymphoma, this screening could help detect HLH early.
Xuzhou, JiangsuAges Any age - NCT06615622Recruiting
Using ultrasound to detect nerve changes in GBS and CIDP
This study tests if ultrasound can find nerve problems in people with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP), and if it helps doctors diagnose and predict outcomes early.
AsyutAges 18–75 - NCT06616363Recruiting
Brain and nerve connection in POTS and after infection
This study looks at why some people develop POTS (a condition that causes a fast heart rate and dizziness when standing) and if it's linked to how the brain and vagus nerve work together. It also includes people recovering from a serious infection and healthy volunteers for comparison.
Richmond, VirginiaAges 12–21 - NCT06619574Recruiting
Testing the dental compass for jaw joint positioning
This study tests a new tool called a Dental Compass that helps dentists place your jaw joint back in the right position more accurately and quickly. It may help relieve TMJ pain and improve jaw function.
Gainesville, TexasAges 18–90 - NCT06622902Recruiting
How flow changes affect CO2 in preemies on high-flow breathing support
This study watches how changing the flow of air through a breathing device (high-flow nasal cannula) affects carbon dioxide levels in preemies. It helps doctors learn the safest way to adjust breathing support for fragile infants.
HaifaAges Any age - NCT06624397Recruiting
A new support program for carers of people with anorexia
This study is testing a support program for carers (family members or partners) of people with severe or hard-to-treat anorexia nervosa. The program is online, so you can join from home, and aims to help carers feel more supported.
Glasgow, ScotlandAges 18 years+ - NCT06625463Recruiting
Heart rehab at home with family support after a heart attack
This study tests a heart rehab program you can do at home, with help from your family. If you've had a heart attack in the past year and don't have other major health issues, this program might help you recover and stay healthy.
Sleman, Special Region of YogyakartaAges 18–65 - NCT06628674Recruiting
Online videos for recovery after rectal cancer surgery
This trial tests if watching online interactive videos can help people who have had surgery for stage I to III rectal cancer deal with common bowel problems after treatment. Your participation could lead to better support tools for other patients.
Taoyuan, 中和區Ages 20 years+ - NCT06633120Recruiting
Growing eggs in the lab for women with PCOS
This study tests a way to mature eggs outside the body for women with PCOS or high ovarian reserve. It might help avoid side effects from fertility medications.
Lone Tree, ColoradoAges Up to 38 years - NCT06637657Recruiting
Optimizing long-term heart disease prevention
This trial tests different ways to manage and reduce the risk of future heart problems in people who have already had a heart attack or a procedure to open blocked heart arteries. The goal is to find the best long-term treatment plan to keep you healthy.
AmsterdamAges 18 years+ - NCT06639178Recruiting
Cream to prevent hand-foot syndrome from capecitabine in breast cancer
This trial tests whether a special cream containing N-acetylcysteine and urea can prevent the painful hand-foot syndrome often caused by the chemotherapy drug capecitabine. If you have breast cancer and are about to start capecitabine, this study may help reduce side effects.
Aviano, PordenoneAges 18 years+ - NCT06639984RecruitingPhase 2
Psyllium for kids with IBS
This study tests if psyllium, a fiber supplement, helps reduce belly pain and other symptoms in children with irritable bowel syndrome (IBS). It may be an option if standard treatments haven't worked well.
Durham, North CarolinaAges 12–17 - NCT06642363RecruitingPhase 1
Astaxanthin for PCOS symptoms and heart health
This trial tests if astaxanthin, a natural antioxidant, can improve PCOS symptoms and heart-related health in women with PCOS who are overweight but not pregnant or breastfeeding.
Isfahan, IsfahanAges 18–45 - NCT06642636Recruiting
Virtual reality before ICU for lung transplant patients
This study tests if a virtual reality experience before entering the ICU can help prepare you. It is for people waiting for a lung transplant.
Rotterdam, South HollandAges 18–71 - NCT06642870Recruiting
Self-management programme for rare rheumatic conditions
This trial is developing a self-management programme for people with rare rheumatic conditions like lupus, vasculitis, myositis, or Sjogren syndrome. It aims to help participants better manage their condition and improve their quality of life.
BristolAges 18 years+ - NCT06644261RecruitingPhase 4
Comparing two methods of nerve block for pelvic pain
This study compares two ways to give a pudendal nerve block—one through the vagina, one through the buttock with X-ray guidance—to see which works better for women with pudendal neuralgia (nerve pain in the pelvic area). It may help find a more effective and comfortable treatment option.
Louisville, KentuckyAges 18 years+ - NCT06645626Recruiting
Health service use and quality of life in atypical Parkinson's
This study looks at how people with certain rare brain conditions (like progressive supranuclear palsy, corticobasal syndrome, or multiple system atrophy) use healthcare services and how their quality of life is affected. It may help doctors better support patients and their carers.
Southampton, HampshireAges 18 years+ - NCT06645691RecruitingPhase 2
Heart and metabolic imaging study using a special MRI scan
This study tests a new MRI method that uses a safe, natural substance (pyruvate) to take detailed pictures of the heart and metabolism. It may help doctors better understand heart disease, diabetes, and related conditions.
SingaporeAges 21–99 - NCT06646809RecruitingPhase 3
Reducing inflammation after colorectal cancer surgery trial
This trial tests a way to reduce inflammation after planned colorectal cancer surgery. It may help you recover better and have fewer complications.
Singapore, SingaporeAges 45 years+ - NCT06650137Recruiting
Using Diaphragm Ultrasound to Find the Cause of Breathing Trouble
This study tests if ultrasound of your diaphragm (the muscle that helps you breathe) can help doctors find the cause of sudden breathing trouble. It may help patients who come to the emergency room with fast or difficult breathing and low oxygen levels.
Nîmes, GardAges 18 years+ - NCT06652087Recruiting
Testing rifaximin for heart failure with preserved pumping
This trial tests whether the antibiotic rifaximin (taken by mouth) can improve heart function in people with a type of heart failure where the heart pumps well but is still weak (HFpEF). Rifaximin might help by changing the bacteria in your gut.
MoscowAges 18–80 - NCT06652750Recruiting
5G cloud-based check-up for heart device patients
This study tests whether a 5G-based remote check-up (over the cloud) is safe and effective for people with certain implanted heart devices, like pacemakers. You'll skip your first clinic visit and instead use a video call or remote check to see how your device is doing.
Guangzhou, GuangdongAges 18 years+
Hear when a new Down Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,173 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.