Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07114055RecruitingPhase 2/Phase 3
Ebastine for diarrhea-predominant IBS
This trial tests whether ebastine, an allergy medicine, can help relieve symptoms of diarrhea-predominant irritable bowel syndrome (IBS-D). If you have IBS-D and are at least 18, this study may offer a new option to manage your condition.
DhakaAges 18 years+ - NCT07141420Enrolling by invitation
Smartphone tool to help ICU recovery
This study tests whether a smartphone tool can help people recover from the long-term effects of being in the ICU. You might be eligible if you had a recent ICU stay and are comfortable using a smartphone.
Guiyang, GuizhouAges 18–100 - NCT03584815Recruiting
Test of physiotherapy versus surgery for exercise leg muscle pressure
This trial compares a physiotherapy program to a surgical procedure (fasciotomy) for chronic “compartment” pressure in the lower leg triggered by exercise. If you have symptoms that reliably come on with walking/running and improve with rest, the study may offer a structured way to find the best treatment for you.
Copenhagen, CopehagenAges 18–50 - NCT03681964Recruiting
Check tests for suspected Sjögren’s syndrome
This study follows people who have signs that might mean Sjögren’s syndrome and looks at how well a standardized work-up identifies the condition. It may help doctors confirm the diagnosis earlier and more consistently.
BrestAges 18 years+ - NCT02967822Recruiting
Study of genes in MRKH syndrome and related families
This study looks at DNA (your genes) to better understand Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome. It may help researchers learn more about the condition, and it can include both people with MRKH and healthy family relatives.
ParisAges Any age - NCT06534853Recruiting
Stretching study for low back pain relief
This study compares two stretching techniques for a condition called quadratus lumborum syndrome, which causes low back or hip pain. Researchers want to see which type of muscle stretch works better to relieve pain and improve movement.
Rawalpindi, Punjab ProvinceAges 18–35 - NCT06196203RecruitingPhase 2
Study of AK117 with Azacitidine for High-Risk MDS
This trial tests a new drug, AK117, combined with azacitidine for people newly diagnosed with high-risk myelodysplastic syndromes (MDS), a blood disorder. The goal is to see if the combination can help improve outcomes.
Los Angeles, CaliforniaAges 18 years+ - NCT03154697Recruiting
Study for parents of children with Smith-Magenis syndrome and sleep issues
This study builds a database about people with Smith-Magenis syndrome and their sleep problems. It wants information from the child’s parent or legal guardian to better understand sleep disturbances.
Washington D.C., District of ColumbiaAges 3–65 - NCT07629505Recruiting
CoQ10 supplement for chronic pelvic pain in men
This trial tests whether a CoQ10 supplement (Ralivia) can reduce chronic pelvic or perineal pain lasting at least 3 months. The study aims to see if this supplement helps relieve symptoms when other treatments haven't fully worked.
ThessalonikiAges 18–50 - NCT06261866Recruiting
Heart imaging for moderate blockages in stable heart disease
This trial tests whether combining two advanced imaging tests (FFR and OCT) can help doctors better decide treatment for moderate blockages in heart arteries. If you have stable chest pain or a positive stress test and a moderate narrowing, this study may help guide your care.
WarsawAges 18 years+ - NCT07628413Recruiting
Exercise Methods for Neck and Shoulder Pain
This study compares two types of gentle exercise programs—Egoscue and Feldenkrais—to help people with chronic neck pain and poor posture. Both programs focus on retraining muscles and improving how your body moves, and the study will measure which approach works better.
Lahore, Punjab ProvinceAges 25–45 - NCT03689842Recruiting
Testing living-donor uterine transplant for MRKH
This study tests whether transplanting a uterus from a living related donor can be done safely and can help patients with MRKH type I achieve pregnancy. It also checks risks and safety issues for both the donor and recipient.
SuresnesAges 18–65 - NCT07270549RecruitingPhase 1/Phase 2
Gene therapy trial for children with CTNNB1 syndrome
This trial tests a one-time gene replacement therapy given into the fluid around the brain to help children with CTNNB1 neurodevelopmental syndrome. The goal is to see if replacing the faulty gene can improve development and reduce symptoms.
LjubljanaAges 2–12 - NCT06778070Recruiting
Pelvic pain study testing yoga therapy for relief
This trial tests whether yoga therapy can help reduce chronic pelvic pain in women and non-binary individuals over 6 months. You'll join online yoga classes and see if they improve your pain and daily life.
San Francisco, CaliforniaAges 18 years+ - NCT07103850Recruiting
Testing a suicide risk questionnaire in Latin America
This trial is testing a new questionnaire to better understand suicidal crisis. It takes place in a hospital intensive care unit and aims to help doctors identify and support people at risk.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07615868RecruitingPhase 1
New blood-thinner study for heart disease patients in China
This study tests a new medication called selatogrel in people with chronic coronary syndrome (long-term heart disease caused by narrowed heart arteries). Researchers want to see how the body processes this drug and whether it helps prevent future heart problems.
BeijingAges 18–85 - NCT07244068Recruiting
Mat Pilates for kids with upper crossed syndrome
This trial tests if Mat Pilates can reduce pain and improve posture in school-going children with a specific forward head and rounded shoulder condition called upper crossed syndrome. It may help your child feel better and stand straighter.
Lahore, Punjab ProvinceAges 8–16 - NCT06706102RecruitingPhase 4
Study of Tiny Blood Particles During CAR-T Therapy
This study is for people getting CAR-T cell therapy, a type of cancer treatment that uses your own immune cells. Researchers want to understand a rare side effect called neurotoxicity by looking at tiny particles in your blood called extracellular vesicles.
Saint-EtienneAges 18 years+ - NCT05090345Recruiting
Registry for young people getting bone marrow transplants
This trial is a registry that follows children and young adults up to age 26 who are having a bone marrow transplant, to better understand complications related to blood vessel and organ injury. It may help future patients by improving how doctors predict and prevent these problems.
Rochester, MinnesotaAges birth–26 years - NCT07059715Recruiting
Studying blood flow during heart surgery for vasoplegia risk
This study looks at blood flow in small and large vessels during heart surgery to understand and predict vasoplegic syndrome, a dangerous drop in blood pressure. It may help find patients at risk and improve their care.
ParisAges 18 years+ - NCT07714031Recruiting
Wrist Release Therapy for Overuse Syndrome
This study tests a special hands-on therapy technique for people with wrist pain from overuse, like computer workers. It may help improve movement and reduce pain without surgery.
Faisalabad, Punjab ProvinceAges 20–50 - NCT05710627Recruiting
Testing TENEX for hip pain from greater trochanteric pain syndrome
This trial studies whether TENEX (a minimally invasive procedure) can reduce hip pain caused by greater trochanteric pain syndrome (GTPS). It is for people who have tried non-surgical treatments for at least 6 months without enough relief, and who have confirmed GTPS on imaging (MRI or CT).
The Bronx, New YorkAges 30–90 - NCT07069010Recruiting
Palliative care education for ICU staff
This trial studies whether a tele-palliative care education program can reduce burnout in ICU clinicians. It involves completing surveys before and during the program.
AthensAges Any age - NCT06694363Recruiting
New test to guide treatment for APDS immune disorder
This study uses a new blood test to find and monitor people with APDS, a rare immune disease, who may be helped by the drug leniolisib. It aims to improve how doctors screen and track treatment response.
BordeauxAges 12 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.