Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07831200Recruiting
Taping and leg strengthening for knee pain
This study compares two types of tape (McConnell and Kinesio) combined with exercises to strengthen the hip and knee, to see which works better for people with pain in the front of the knee, especially when squatting or climbing stairs.
Islamabad, Punjab ProvinceAges 26–44 - NCT07832994Recruiting
Exercise for teens with celiac disease, metabolic syndrome, and fatty liver
This trial tests whether a specific exercise program can improve metabolic syndrome and fatty liver in teenage girls with celiac disease. It may help reduce liver fat and improve overall health.
Giza, DokkiAges 13–17 - NCT07833007Recruiting
Dietary changes for metabolic syndrome in teens with familial Mediterranean fever
This trial tests whether limiting certain foods can improve metabolic syndrome (a group of conditions like high blood sugar and extra belly fat) in teenagers who also have familial Mediterranean fever (a genetic condition causing repeated fevers and inflammation). It may help manage both conditions together.
Giza, DokkiAges 13–17 - NCT06338735Recruiting
High-frequency ultrasound for Sjögren's diagnosis
This study uses a special, very high-frequency ultrasound to take detailed images of the small glands that can be affected in Sjögren's syndrome. The goal is to see if this new ultrasound technique can help doctors diagnose Sjögren's more accurately.
PisaAges 18 years+ - NCT07824050Recruiting
Studying dangerous heart rhythms after a heart attack
This study looks at people who had a heart attack or cardiac arrest to find out which dangerous heart rhythms can happen afterward. The goal is to improve care and prevent future problems.
Eindhoven, North BrabantAges 18 years+ - NCT07825155RecruitingEarly Phase 1
Injections for carpal tunnel syndrome: comparing three treatments
This study compares three different injections for carpal tunnel syndrome, a condition where a nerve in your wrist gets squeezed, causing pain, numbness, or tingling in your hand. The goal is to see which injection works best to relieve symptoms.
Tanta, Gharbia GovernorateAges 18–70 - NCT07824323RecruitingPhase 4
Early cholesterol treatment after a heart attack
This study tests whether adding an extra cholesterol-lowering drug (bempedoic acid) to the usual treatment soon after a heart attack or related event can lower 'bad' cholesterol more effectively. It may help reduce the risk of future heart problems.
Taipei, Taipei CityAges 18 years+ - NCT07819916Recruiting
Exercises for flexible flat feet without pain
This trial tests a specific set of exercises to see if they can improve flexible flat feet. It may help if you have flat feet that are not painful and can flex.
LahoreAges 20–40 - NCT07822360Recruiting
Acne and hormonal imbalance risk in young women
This study looks at how common polyendocrine metabolic ovarian syndrome (PMOS), a hormonal condition, is in women with acne. It aims to find if acne could be a sign of this condition, which might help with early detection and treatment.
SohagAges 15–49 - NCT05994664Recruiting
Heart Coherence Training for Vascular Ehlers-Danlos
This study tests whether a breathing and heart-rate training program (called Heart Coherence Training) can help people with Vascular Ehlers-Danlos syndrome feel better. It's done from home using your phone and a computer or tablet.
Houston, TexasAges 12–45 - NCT07813455Recruiting
Ultrasound-guided injection for piriformis syndrome pain
This study tests whether adding a special fluid injection around the piriformis muscle to a standard ultrasound-guided injection provides better pain relief for people with piriformis syndrome. If you qualify, you'll receive the injection and be followed for a short time to see how well it works.
Istanbul, UskudarAges 18–70 - NCT07801001Enrolling by invitation
Zinc supplements for women with polycystic ovary syndrome
This study tests whether taking zinc supplements can improve insulin resistance and reduce symptoms in women with polycystic ovary syndrome (PCOS). If you have PCOS and are not pregnant, you may be able to join.
DhakaAges 18–45 - NCT06512493Recruiting
South East Netherlands Heart Registry
This is a heart registry that collects information from all patients to get a complete picture of heart care in the region. By including everyone, it aims to improve future treatments without bias.
Heerlen, LimburgAges Any age - NCT07793487Enrolling by invitation
Testing a special dairy drink for gut and metabolic health
This study tests whether a special dairy product can help improve symptoms in people with irritable bowel syndrome or early signs of metabolic syndrome. Participants must be at a healthy weight and not have other major health conditions or be on certain diets.
WarsawAges 18 years+ - NCT05230017Recruiting
Study to follow people with antiphospholipid antibodies
This study looks at people who test positive for antiphospholipid antibodies on more than one blood test. It helps researchers better understand the condition and how to follow patients over time.
Beijing, Beijing MunicipalityAges Any age - NCT06528197Recruiting
Building a better treatment model for Sjögren's syndrome
This study is building a new model to help doctors treat primary Sjögren's syndrome using a combination of traditional Chinese medicine and Western medicine. It may help find better ways to manage your symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT06530004Recruiting
Rituximab for childhood nephrotic syndrome: a follow-up study
This study follows children with nephrotic syndrome (a kidney condition causing swelling) who are being treated for the first time with rituximab. It aims to see how well the medication works long-term.
Xiamen, FujianAges 1–18 - NCT06090110Recruiting
Vagus nerve stimulation for irritable bowel syndrome
This study tests whether a gentle electrical device that stimulates the vagus nerve can help relieve symptoms of irritable bowel syndrome. If you have IBS and are between 18 and 75, you may be able to join.
Maastricht, LimburgAges 18–75 - NCT07785011Recruiting
Sensory integration for gross motor and balance in children with Down syndrome
This study tests whether sensory integration therapy helps improve gross motor skills and balance in children with Down syndrome. It focuses on kids aged 3-5 who can stand alone and have specific IQ and sensory issues, while excluding those with heart problems, severe cognitive issues, recent leg surgery, obesity, or hip problems.
CairoAges 3–5 - NCT07782827RecruitingPhase 3
Angel syndrome treatment study for children and adults
This study tests an experimental medicine for Angelman syndrome (AS), a genetic condition affecting the nervous system. The medicine is given by lumbar puncture and aims to improve symptoms.
Carrboro, North CarolinaAges 2–50 - NCT07778810RecruitingPhase 2
Cannabidiol before seizures in infants with Sturge-Weber syndrome
This study tests whether starting the medication Epidiolex (a purified form of cannabidiol) before any seizures occur can help prevent or delay seizures in infants with Sturge-Weber syndrome.
Baltimore, MarylandAges 1 month–1.5 years - NCT07780240Recruiting
Understanding arm band pain after breast cancer surgery
This study looks at how common axillary web syndrome (a rope-like band in the armpit after breast cancer surgery) is, who gets it, and how it affects arm function. It aims to help doctors better predict and manage this condition.
Istanbul, BAGCILARAges 18–80 - NCT03764748RecruitingPhase 1
Washed stool transplant for Tourette syndrome in kids
This Phase 1 study tests whether a “washed” stool microbiota transplant can reduce Tourette syndrome tics in children. It aims to see if changing gut bacteria is safe and may improve tic severity.
Nanjing, JiangsuAges 6–17 - NCT05221021RecruitingPhase 4
Vaginal estrogen vs oral bladder medicine for overactive bladder
This study compares vaginal estradiol (a hormone placed in the vagina) versus an oral beta-3 medicine called mirabegron for overactive bladder symptoms. It looks to see which treatment works better and is safer for postmenopausal women.
Bethesda, MarylandAges 18 years+
Hear when a new Down Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.