Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07860021RecruitingPhase 2/Phase 3
Vyvgart for stiff person syndrome
This trial tests whether a drug called Vyvgart (hyaluronidase-fjjo) can help people with stiff person syndrome who still have symptoms like stiffness, painful muscle spasms, and trouble walking despite other treatments. The goal is to see if it improves these symptoms and how well it works.
Philadelphia, PennsylvaniaAges 25–80 - NCT06271083Recruiting
Online behavior therapy for Tourette syndrome in adults
This trial tests an online behavior therapy program for adults with Tourette syndrome or chronic tic disorder. You'll complete a 10-week internet-based treatment from home, with therapist support, to help reduce your tics.
StockholmAges 18 years+ - NCT02753335Recruiting
Rehabilitation for complex regional pain syndrome
This study tests a comprehensive rehabilitation program for adults with complex regional pain syndrome (CRPS), a chronic pain condition usually affecting one arm or leg. It looks at how the program affects pain and brain function, aiming to improve daily life.
TromsøAges 18–70 - NCT05731830Recruiting
Study how air pollution relates to Takotsubo heart episodes
This study looks at whether levels of air pollution are linked to Takotsubo syndrome (a temporary heart condition). It may help doctors understand what environmental factors could affect episodes and timing.
RomeAges 18 years+ - NCT05805566Recruiting
Study of care for long COVID symptoms in adults
This study follows people who enter a specialized care pathway for long COVID (post-COVID syndrome) to better understand symptoms, needs, and outcomes. It may help improve how multidisciplinary care is organized for long COVID over time.
Pierre-BéniteAges 18 years+ - NCT05198661Recruiting
Blood or spinal fluid study in autoimmune brain disorders
This study collects information from people with autoimmune encephalitis or related nerve/brain disorders, using blood and sometimes spinal fluid. It helps researchers better understand these conditions, which may guide future diagnosis and treatments.
Pointe à Pitre, GuadeloupeAges Any age - NCT07854041Recruiting
Release techniques for kneecap pain
This study tests two hands-on therapies to ease kneecap pain. It may help if your pain has lasted at least three months and gets worse with stairs, running, or sitting for a long time.
Lahore, Punjab ProvinceAges 15–40 - NCT06202846Recruiting
Looking for Y chromosome in Turner syndrome blood
This study looks for a tiny piece of the Y chromosome (a sex chromosome normally found in males) in a blood sample. It may help doctors better understand Turner syndrome and find hidden Y chromosome material that could affect health.
LyonAges 2–74 - NCT06013319RecruitingPhase 3
Esmolol for better oxygen in ARDS patients
This trial tests if esmolol, a heart-slowing drug, can improve oxygen levels in patients with acute respiratory distress syndrome (ARDS) who are on a breathing machine. It may help by adjusting heart rate to a specific range.
Jinan, ShandongAges 18–65 - NCT06279663Recruiting
Comparing bypass surgery vs stenting for high-risk heart attacks
This study compares two common treatments (bypass surgery vs. stenting) for people having a high-risk heart attack that involves blockages in multiple arteries. It aims to find which approach leads to better long-term outcomes.
Novosibirsk, Novosibirsk OblAges 18 years+ - NCT03154697Recruiting
Study for parents of children with Smith-Magenis syndrome and sleep issues
This study builds a database about people with Smith-Magenis syndrome and their sleep problems. It wants information from the child’s parent or legal guardian to better understand sleep disturbances.
Washington D.C., District of ColumbiaAges 3–65 - NCT04243785RecruitingPhase 1
Testing BTX-A51 for hard-to-treat AML or high-risk MDS
This Phase 1 study tests BTX-A51 in adults with relapsed or refractory acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS). It’s designed to see if the treatment can be given safely and to learn how it works in people whose standard treatments have not helped or are no longer an option.
Duarte, CaliforniaAges 18 years+ - NCT06325618Recruiting
Studying lymphedema and blood vessels in Turner syndrome
This study looks at swelling (lymphedema), inflammation, and blood vessels in women with Turner syndrome. It uses MRI scans to understand these issues better.
Aarhus NAges 18–100 - NCT04151693Recruiting
Group therapy for chronic fatigue syndrome
This trial tests a health-psychology–based rehabilitation program delivered in a group setting for people with chronic fatigue syndrome (ME/CFS). It may help by teaching strategies to cope with symptoms and improving daily functioning through structured group support.
LahtiAges 18–65 - NCT06115083Recruiting
Pelvic floor training for men with chronic pelvic pain
This trial tests if pelvic floor muscle training can reduce chronic pelvic pain in men. It also looks at how well patient-reported symptoms match physical exam findings.
StockholmAges 18 years+ - NCT06171061RecruitingPhase 4
Yangxinshi tablets for better exercise in heart disease
This study tests if Yangxinshi tablets can help people with chronic coronary syndrome (a type of heart disease) walk farther or exercise longer. It's for those whose heart condition limits their daily activity.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT05679206Recruiting
Postpartum care study for pregnancy blood-pressure complications
This study looks at people with preeclampsia during pregnancy and how their lung blood pressure and related symptoms change after delivery. It may help doctors better monitor and manage postpartum risks, especially involving the heart and lungs.
BernAges 16 years+ - NCT04650880Recruiting
Vitamin D study for irregular periods from PCOS
This trial studies whether taking vitamin D can improve ovulation (the release of an egg) in people with PCOS who have long, irregular menstrual cycles. It may help some participants have more regular ovulation and cycle timing, but you would be monitored with vaginal ultrasound and blood tests.
Hong KongAges 18–40 - NCT07846462Recruiting
Aspirin dose comparison after heart stent placement
This study compares two different daily doses of aspirin (50 mg vs 100 mg) when taken with a standard blood thinner (P2Y12 inhibitor) after getting a heart stent. It aims to see if a lower aspirin dose works just as well with fewer side effects.
Changchun, JilinAges 18–85 - NCT06393101RecruitingPhase 1
High-CBD cannabis extract for complex regional pain syndrome treatment
This study tests a high-CBD cannabis extract (BRC-002) to see if it can help reduce pain and improve health in people with Complex Regional Pain Syndrome (CRPS). Participants will not use opioids or other cannabis during the study.
La Jolla, CaliforniaAges 21–75 - NCT04240834RecruitingPhase 4
Low-dose ticagrelor vs aspirin after heart stent placement
This study compares ticagrelor taken at a lower dose versus regular aspirin to help prevent future heart attacks in people who recently had a stent placed after acute coronary syndrome. You may qualify if you’re considered “high risk” for new blockages or clots and can take dual anti-platelet therapy for 12 months.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07838558Recruiting
Comparing two muscle-relaxing exercises for lower back pain
This study compares two muscle-relaxing techniques to help people with lower cross syndrome, a common cause of low back pain and poor posture. If you join, you'll receive one of these physiotherapy approaches to see which works better for relieving your pain.
Islamabad, Punjab ProvinceAges 19–35 - NCT07834151Recruiting
Kinetic chain training plus standard exercises for shoulder pain
This study tests whether adding kinetic chain training (exercises that involve the whole body, like the legs and core) to standard shoulder exercises helps reduce shoulder pain and improve movement in people with subacromial pain syndrome, a common cause of shoulder pain.
Islamabad, Punjab ProvinceAges 35–60 - NCT07833007Recruiting
Dietary changes for metabolic syndrome in teens with familial Mediterranean fever
This trial tests whether limiting certain foods can improve metabolic syndrome (a group of conditions like high blood sugar and extra belly fat) in teenagers who also have familial Mediterranean fever (a genetic condition causing repeated fevers and inflammation). It may help manage both conditions together.
Giza, DokkiAges 13–17
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.