Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07747909Recruiting
Orlistat for metabolic and hormonal health in PCOS
This study tests whether the weight-loss drug orlistat can improve blood sugar, hormones, and other metabolic measures in women with polycystic ovary syndrome (PCOS). If you have PCOS and are overweight, this treatment might help with symptoms like irregular periods and excess hair growth.
Abbottābād, Khyber PakhtunkhwaAges 18–45 - NCT07743242Recruiting
Study of hemolytic anemia in antiphospholipid syndrome
This study looks at how autoimmune hemolytic anemia (when the body attacks its own red blood cells) relates to antiphospholipid syndrome (a condition that increases blood clot risk). It aims to better understand this connection, which may help improve care for people with both conditions.
Al Khārjah, Kharga OasisAges 18 years+ - NCT07746635Recruiting
Fecal transplant for obese women with polyendocrine ovarian syndrome
This study tests whether a fecal microbiota transplant (putting healthy bacteria from a donor into your gut) can help women with polyendocrine ovarian syndrome and obesity improve their chances of a successful frozen embryo transfer. It may help by balancing the bacteria in your gut, which could improve your overall health and fertility.
Shanghai, Shanghai MunicipalityAges 20–40 - NCT06622915Recruiting
Heart health in kids with kidney condition
This study looks at how different types of nephrotic syndrome affect heart function in children. It may help doctors understand the heart risks in kids who need steroids for a long time compared to those whose condition doesn't respond to steroids.
SohagAges 2–14 - NCT07737561Recruiting
Exercise test for heart, kidney, and metabolic health
This study looks at how blood pressure and artery stiffness respond to exercise in people with heart, kidney, and metabolic problems. It may help doctors better understand your condition.
KaramanAges 18 years+ - NCT07734051Enrolling by invitation
Mobilization for kneecap pain
This trial tests if adding a groin-area mobilization to foot mobilization helps with kneecap (patellofemoral) pain. It may be for you if you have one-sided kneecap pain for at least 3 months, especially when climbing stairs, squatting, or sitting for long periods.
Fāqūs, SharkeyaAges 18–40 - NCT07736144Recruiting
Herbal formula study for fibromyalgia pain relief
This study tests a Chinese herbal formula called Yangyin Roujin (which nourishes yin and softens the muscles) to see if it helps reduce pain and other symptoms of fibromyalgia. If you have fibromyalgia and a pain level of 4 or more, you may be able to join.
Beijing, Beijing MunicipalityAges 18–75 - NCT07735156Recruiting
Treating Pelvic Pain with Vein Blockage
This study tests a minimally invasive procedure that blocks abnormal veins in the pelvis to relieve long-term pelvic pain. It may help women with pelvic congestion syndrome.
Sohag, Sohag GovernorateAges 17–55 - NCT07738107RecruitingPhase 1/Phase 2
Study of ATR 1072 for PRKAG2 syndrome
This trial tests a new medicine called ATR 1072 for people with PRKAG2 syndrome, a genetic heart condition. It aims to see if the drug is safe and can help manage symptoms.
Kansas City, MissouriAges 18–65 - NCT05012475Recruiting
Test whether video games help arm movement in Rett syndrome
This trial looks at whether computer gaming can improve how well you can use your arms to control game actions in Rett syndrome. It checks whether the gaming tasks can be done safely based on your arm movement range.
Washington D.C., District of ColumbiaAges 4–60 - NCT07727538RecruitingPhase 3
Olezarsen for familial chylomicronemia syndrome in children and teens
This study tests a new medicine called olezarsen to lower very high triglycerides (fats) in the blood of children and teenagers with familial chylomicronemia syndrome (FCS), a rare genetic condition. The goal is to reduce the risk of pancreatitis and other complications.
Birmingham, AlabamaAges 2–17 - NCT07724574Recruiting
Comparing two posture treatments with breathing exercises
This study compares two different muscle-strengthening approaches (Kendall vs. Janda) combined with diaphragmatic breathing exercises to improve posture and symptoms in people with upper crossed syndrome (forward head and rounded shoulders).
Sialkot, Punjab ProvinceAges 30–50 - NCT07725926Recruiting
Combining therapy techniques for tic-like OCD
This study tests a therapy that combines two approaches—one for tics and one for OCD—to help people whose OCD feels like it's linked to tics. The goal is to see if this combined treatment reduces distressing urges and repetitive behaviors.
London, LondonAges 18–65 - NCT07730931Recruiting
Breathing test for lung problems after bone marrow transplant
This study tests a simple breathing test called Forced Oscillatory Technique (FOT) to detect early signs of a lung condition called bronchiolitis obliterans syndrome after a bone marrow transplant. Participating involves breathing normally into a mouthpiece during your regular lung function test.
JerusalemAges 6 months+ - NCT07722247Recruiting
Eye stiffness and healing in cataract surgery with PEX
This study looks at how your eye's outer layer (cornea) heals and changes shape after cataract surgery, specifically comparing people who have pseudoexfoliation syndrome (PEX) with those who do not. The goal is to see if PEX affects the final vision result after cataract removal.
Split, Splitsko-dalmatinska CountyAges 50–85 - NCT07718958Recruiting
Biomarkers for PANS in children
This study looks for blood markers that could help diagnose and track pediatric acute-onset neuropsychiatric syndrome (PANS). If your child has PANS, participating could help improve understanding and treatment of this condition.
Cagliari, CagliariAges 3–18 - NCT05719246Recruiting
Yoga and meditation for teens with IBS stress
This study tests a structured yoga and meditation program to help reduce stress symptoms in teens with irritable bowel syndrome (IBS). It may help your teen learn calming practices that could ease how stress affects IBS.
Camden, New JerseyAges 12–21 - NCT06642831Recruiting
PCOS biomarker study for young women
This study looks for biological markers of polycystic ovary syndrome (PCOS) in young women. If you are between 15 and 25 and have not used hormonal birth control recently, you may be able to help researchers find better ways to diagnose PCOS.
ErlangenAges 15–25 - NCT07710196RecruitingPhase 3
NPI-001 for preserving vision in usher syndrome
This study tests a 24-month treatment with NPI-001, an oral medication, to see if it can slow the loss of light-sensing cells in the retina for people with retinitis pigmentosa tied to Usher syndrome. It aims to preserve remaining vision and delay further damage.
Dallas, TexasAges 18 years+ - NCT07710274Recruiting
Personalized Program for Insulin Resistance in Metabolic Syndrome
This pilot study tests a personalized program called PRISM to help improve how your body responds to insulin. If you have metabolic syndrome (a cluster of conditions like large waist size, high blood pressure, or high blood sugar) and insulin resistance, the study will use a continuous glucose monitor, smart ring, and food logging app to give you tailored feedback.
SingaporeAges 21–70 - NCT07711964RecruitingPhase 4
Finding the best steroid dose for ARDS patients on a ventilator
This trial tests different doses of corticosteroids to find the best one for people with acute respiratory distress syndrome (ARDS) who are on a breathing machine. It aims to improve recovery while reducing side effects.
TaipeiAges 18 years+ - NCT07714031Recruiting
Wrist Release Therapy for Overuse Syndrome
This study tests a special hands-on therapy technique for people with wrist pain from overuse, like computer workers. It may help improve movement and reduce pain without surgery.
Faisalabad, Punjab ProvinceAges 20–50 - NCT04981145RecruitingPhase 4
Iguratimod for Sjögren’s syndrome symptoms and safety
This trial studies whether iguratimod improves symptoms in people with primary Sjögren’s syndrome, and checks how safe it is. It focuses on people with confirmed disease markers (anti-SSA/Ro-60) and ongoing dry eyes and dry mouth.
Hangzhou, ZhejiangAges 18–70 - NCT07704047RecruitingPhase 2
Study of FT1 for short bowel syndrome
This study tests a new treatment called FT1 for people with short bowel syndrome. It aims to help you absorb more nutrients and fluids from food, potentially reducing the need for IV nutrition.
Nanjing, JiangsuAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.