Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,201 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06104631Recruiting
Testing a treatment for IBS-like symptoms in Crohn's remission
This study tests whether a new treatment can reduce IBS-like symptoms, such as belly pain and bloating, in people whose Crohn's disease is in remission. It aims to improve your quality of life without targeting active Crohn's inflammation.
LiègeAges 18–75 - NCT06503003Recruiting
Laser therapy for menopause symptoms
This study tests a non-surgical laser treatment to help with vaginal dryness, burning, pain during sex, and other symptoms caused by menopause. The goal is to see if it can safely improve quality of life and sexual health.
Cagliari, CAAges 45–73 - NCT05984394Recruiting
Study of immune cells in new antisynthetase syndrome with lung disease
This study looks at special immune cells (T cells) in people newly diagnosed with antisynthetase syndrome that has affected their lungs. It aims to understand how these cells are involved in the condition, which could lead to better treatments.
DijonAges 18 years+ - NCT07276568Enrolling by invitationEarly Phase 1
Hepatocyte-like cell injection for small liver syndrome
This early-phase trial tests an injection of lab-grown liver cells into the stomach muscle to prevent or treat small-for-size syndrome, a condition where a partial liver graft is too small. It may also help people with acute or chronic liver failure.
Beijing, ProvinceAges Any age - NCT07324733Recruiting
PSMA PET scan for Sjögren's syndrome
This study uses a special PET scan called PSMA to look at inflammation in Sjögren's syndrome, comparing the results with another type of PET scan (FAPI). It may help doctors better understand the disease and find new ways to track it.
BeijingAges 18–80 - NCT07254299Recruiting
Hypnosis for ICU recovery and wellbeing
This study tests whether hypnosis sessions during an ICU stay can improve mental and physical recovery after a serious illness. It aims to reduce long-term problems like anxiety, depression, and memory issues.
GenevaAges 18 years+ - NCT07424222RecruitingPhase 1
Ruxolitinib for a serious immune reaction after CAR T therapy
This trial tests a drug called ruxolitinib for a rare but serious condition called IEC-HS that can happen after CAR T cell treatment. The goal is to see if ruxolitinib can calm this overactive immune response.
Baltimore, MarylandAges 18–99 - NCT06660329Enrolling by invitationPhase 4
Tofacitinib for hard-to-treat Blau syndrome
This study tests if the drug tofacitinib (a JAK inhibitor) can help people with Blau syndrome whose symptoms did not improve with other treatments. Blau syndrome is a rare genetic condition that causes inflammation in the skin, joints, eyes, and other organs.
BeijingAges birth–18 years - NCT07354438Recruiting
Antioxidant-rich diet for metabolic syndrome risk
This study tests whether eating more foods rich in antioxidants (like fruits and vegetables) can help lower your risk of metabolic syndrome, a condition that increases your chance of heart disease and diabetes. If you have a larger waist size and higher blood pressure, and you don't eat many fruits and vegetables, this trial may be a good fit.
Lahore, Punjab ProvinceAges 18–45 - NCT06528197Recruiting
Building a better treatment model for Sjögren's syndrome
This study is building a new model to help doctors treat primary Sjögren's syndrome using a combination of traditional Chinese medicine and Western medicine. It may help find better ways to manage your symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT06797414Recruiting
Pilates with or without vibration for upper cross syndrome
This study compares Pilates exercises with and without whole-body vibration (a platform that gently shakes your body) to see which better improves posture and pain in people with upper cross syndrome (a common pattern of rounded shoulders and forward head). It aims to find a more effective way to strengthen muscles and reduce discomfort.
Lahore, Punjab ProvinceAges 20–40 - NCT05734794RecruitingPhase 3
Rituximab for new childhood nephrotic syndrome
This trial studies whether rituximab alone can help children with new-onset idiopathic nephrotic syndrome. It compares the treatment approach in order to see if it improves kidney recovery and reduces disease activity.
Hangzhou, ZhejiangAges 2–17 - NCT05663216Recruiting
Study of fluid leaks in serious whole-body inflammation
This trial looks at what causes blood vessels to “leak” fluid during a dangerous whole-body inflammation response. It may help doctors understand why some people develop fluid buildup and aim for better monitoring and care in the ICU.
ParisAges 18 years+ - NCT07186764Recruiting
Quality of life in women with MRKH syndrome
This study tracks quality of life and follow-up care in women with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome, a condition where the uterus and upper vagina are underdeveloped or absent. It compares their experiences to women without MRKH to improve care.
ToulouseAges 18–50 - NCT07182461Recruiting
Taping and exercises for upper crossed syndrome
This study tests if wearing a special tape and doing corrective exercises can help with neck and shoulder posture and muscle balance. It might be a good option if you have poor posture called upper crossed syndrome.
Taichung, BeitunAges 20–35 - NCT03687814Recruiting
Low FODMAP diet plus PEG for IBS with constipation
This study tests whether a low-FODMAP diet combined with PEG 3350 can reduce symptoms in adults with IBS-C (irritable bowel syndrome with constipation). It may help improve bowel habits and abdominal pain, and it checks which people can safely follow the diet and treatment plan.
Ann Arbor, MichiganAges 18 years+ - NCT07642232Recruiting
Somatic Movement vs Core Strengthening for Premenstrual Syndrome
This study compares two exercise approaches—somatic movement therapy (mindful, body-awareness exercises) and core strengthening—to see which better reduces premenstrual syndrome symptoms like mood changes and physical discomfort. You'd participate in one type of exercise program over several weeks.
Lahore, Punjab ProvinceAges 18–35 - NCT07091123RecruitingPhase 4
Comparing two treatments for chronic back pain after surgery
This study compares two treatments for long-term back pain after surgery: a spinal cord stimulator (a device that sends mild electrical pulses to your spine) and a pump that delivers pain medicine directly to your spinal fluid. It will look at which treatment you prefer and how well it works over time.
Cleveland, OhioAges 30 years+ - NCT07606755RecruitingPhase 4
Jinfeng Pill for Hot Flashes and Menopause Symptoms
This study tests whether a traditional Chinese medicine called Jinfeng Pill can reduce hot flashes, night sweats, sleep problems, mood changes, and other symptoms during perimenopause (the transition to menopause, typically ages 45–55). Researchers want to see if this treatment works better than standard options.
Wuhan, HubeiAges 45–55 - NCT06083597Enrolling by invitation
Developing a pelvic pain questionnaire for women
This study aims to develop a new questionnaire to better understand and measure chronic pelvic pain in women, especially when it's linked to enlarged pelvic veins. You will be asked to take part in interviews and fill out surveys to help create a tool that reflects your experience.
New York, New YorkAges 18–60 - NCT06742073Recruiting
Study of H syndrome and inflammation
This study looks at the link between H syndrome and related health issues, such as inflammation or histiocytosis (a type of immune cell disorder). It helps researchers learn more about how this rare genetic condition affects the body.
Petah TikvaAges Any age - NCT06988930Enrolling by invitation
Comparing two treatments for lateral patellar crush syndrome
This trial compares two treatments for lateral patellar crush syndrome: a type of knee surgery called lateral retinacular release versus specific exercises. The goal is to see which approach works better for reducing pain and improving function.
BeijingAges Any age - NCT06873971Recruiting
Laser plus vaginal estrogen for menopause symptoms
This trial tests if combining a special laser treatment with a vaginal estrogen cream can help relieve menopause symptoms like vaginal dryness, burning, and pain during sex. It may be a good option for women who have not used hormone therapy recently.
São Paulo, São PauloAges 45–70 - NCT06739434Enrolling by invitation
Gene therapy for Rett syndrome in girls
This trial tests a new gene therapy called GCB-002 for girls with Rett syndrome caused by a MECP2 gene change. It may help improve symptoms by targeting the root genetic cause.
Shanghai, Shanghai MunicipalityAges 2–10
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,201 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.