Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03908463Recruiting
Heart procedure registry for people who get coronary angioplasty
This trial is a registry that collects health information from adults who undergo a heart procedure called coronary angioplasty. It may help researchers understand outcomes and improve care for future patients undergoing similar treatments.
SeoulAges 19 years+ - NCT06090591Recruiting
Heart condition research registry at Dubrava Hospital
This study is a registry that will collect information from people with certain heart conditions (like having a pacemaker, a blood clot, a heart attack, or a valve replacement procedure called TAVI). The goal is to learn more about these conditions and how they are treated.
ZagrebAges 18 years+ - NCT06283888RecruitingPhase 4
Choosing a blood thinner based on your genes after complex heart treatment
This trial tests whether choosing a blood thinner based on your DNA can prevent more heart problems. If you've had a complex heart procedure, you may be able to get a medication that works best for your body.
Zunyi, GuizhouAges 18–80 - NCT06329999Recruiting
CMGV for recurrent AML and high-risk MDS
This study tests a new treatment called CMGV for adults whose acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) has returned or is not improving. It is for people who may be older or have had other blood disorders.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06336070Recruiting
Power training for metabolic health in postmenopausal cancer survivors
This trial compares two types of exercise—muscle power training and metabolic power training—to see which better improves your body's ability to use energy and control heart function. You may qualify if you are a postmenopausal woman who has had breast cancer and is not currently active.
Valencia, ValenciaAges 35–75 - NCT06323018Recruiting
Remote preconditioning for cemented hip replacement recovery
This trial tests whether a simple, safe treatment called remote ischemic preconditioning (using a blood pressure cuff on your arm just before surgery) can help people recover better after cemented hip replacement. It is for patients aged 66 and older who are scheduled for this surgery.
Tartu, TartuAges 65–90 - NCT04158479Recruiting
Registry for people on ECMO life support
This registry collects information about people who are placed on ECMO, a heart-lung machine used to support breathing and/or circulation. It may help doctors better understand who benefits and how to manage ECMO in the future.
Beijing, Beijing MunicipalityAges Any age - NCT05856318Recruiting
Study heart and diabetes health in first-time pregnancy
This study looks at how your heart health and blood-sugar health change when you are trying for, or not planning, a first pregnancy. It may help researchers understand which early health factors matter for you and future pregnancy outcomes.
CambridgeAges 18–45 - NCT06206174RecruitingPhase 1/Phase 2
Study of TGRX-814 for blood cancers
This trial tests a new drug called TGRX-814 for people with certain blood cancers like non-Hodgkin's lymphoma, acute lymphoblastic leukemia, acute myeloid leukemia, or myelodysplastic syndromes. It aims to see if the drug is safe and effective.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06360965Recruiting
Acupoint patch for pelvic pain after PID
This trial tests a skin patch treatment (acupoint application) placed on specific points of the body to help relieve ongoing pelvic pain from pelvic inflammatory disease. It may be a good option if you have moderate pain and ultrasound findings of tubal thickening or fluid.
BeijingAges 18–50 - NCT03999723RecruitingPhase 2
Test azacitidine with vitamin C to improve DNA changes
This Phase 2 study tests whether combining azacitidine (a standard blood cancer medicine) with vitamin C helps improve disease control by changing DNA activity in high-risk blood cancers. It may be an option if you have certain types of higher-risk MDS, CMML, or low-blast AML and can meet safety requirements.
AalborgAges 18 years+ - NCT06373341Recruiting
Virtual reality rehab for arm and hand after ICU stay
This study tests whether using virtual reality (VR) games can help you regain movement and strength in your arms and hands after a long hospital stay in the ICU. It is designed for people who live in the Frisian region of the Netherlands and can understand Dutch.
Leeuwarden, Provincie FrieslandAges 18 years+ - NCT05008744Recruiting
Laser treatment for twin-to-twin transfusion using one shared placenta
This study tests a laser procedure that seals abnormal blood vessel connections in identical twins sharing one placenta (twin-to-twin transfusion syndrome). The goal is to improve outcomes by stopping unbalanced blood flow between the twins.
Seattle, WashingtonAges Any age - NCT06377878Recruiting
The Preeclampsia Registry
This study is building a registry of people who have had preeclampsia or related high blood pressure disorders during pregnancy, as well as their family members and healthy volunteers. The goal is to collect information that can help researchers better understand these conditions and improve care.
Melbourne, FloridaAges 13 years+ - NCT03749980Recruiting
Study following people with von Hippel-Lindau (VHL)
This study follows people who have von Hippel-Lindau (VHL) over time to better understand how the condition changes. It may help doctors plan future treatments by collecting long-term health information.
Boston, MassachusettsAges Any age - NCT06161701Recruiting
Steroid-related diabetes in kidney disease patients
This trial looks at how steroids affect blood sugar in people with certain kidney diseases. If you are starting steroid treatment, this study may help understand and manage the risk of developing diabetes.
Hangzhou, ZhejiangAges 18–75 - NCT06394934Recruiting
Home blood pressure changes and artery health in hypertension
This study looks at how changes in home blood pressure readings over time relate to hardening of the arteries and metabolic problems in people with high blood pressure. If you take medication for high blood pressure and monitor your pressure at home, you may help researchers understand these connections better.
SeoulAges 19 years+ - NCT04173715Recruiting
Study measuring movement and behavior in older adults
This study checks how well you move and how you behave during simple tasks. It may help researchers understand physical function and activity patterns in older adults.
ToledoAges 65 years+ - NCT04186286RecruitingPhase 2
Testing propranolol vs ivabradine for POTS symptoms
This study compares two heart-rate medicines—propranolol and ivabradine—to see which better improves symptoms in people with POTS. It uses a “crossover” design, meaning you may try one medicine and then switch to the other.
Calgary, AlbertaAges 18–60 - NCT02355457Recruiting
Blood marker study in new heart attack symptoms
This study looks at blood “biomarkers” (signals in blood tests) in people who arrive with symptoms that could be a heart attack. It may help doctors spot and manage acute heart problems sooner and more accurately.
HamburgAges 18 years+ - NCT06410833RecruitingPhase 4
Combination therapy for resistant Sjögren's in children
This trial tests a combination of two medicines, rituximab then belimumab, for children and teens with Sjögren's syndrome that hasn't improved with other treatments. The goal is to see if this two-step approach can better control symptoms like joint pain, skin rashes, and blood problems.
Beijing, Beijing MunicipalityAges 5–18 - NCT06421818RecruitingPhase 2
Baitouweng Decoction for ulcerative colitis with damp-heat
This trial tests a traditional Chinese herbal formula called Baitouweng Decoction for people with mild to moderate ulcerative colitis who also have a specific pattern of symptoms called 'damp-heat' in the large intestine. It aims to see if the medicine can help reduce inflammation and improve symptoms.
Nanjing, JiangsuAges Any age - NCT06365502Recruiting
Preventing future heart attacks with drug-coated balloon
This trial tests whether a balloon coated with medicine (drug-coated balloon) can prevent future heart attacks by treating high-risk plaques in arteries that are not the one that caused your current heart attack. You may qualify if you already had a stent placed and have another mildly blocked artery with certain vulnerable features.
Beijin, Beijing MunicipalityAges 18–80 - NCT05740579Recruiting
Storing eggs in teens with Turner syndrome variants
This study looks at freezing and storing eggs (cryopreservation) in children and teens with Turner syndrome or related genetic variants. It may help preserve the chance of having biological children later, if you are able to undergo the study procedures safely.
AarhusAges 2–17
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.