Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,201 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04871035Recruiting
Compare immunoadsorption vs plasma exchange for Guillain-Barré
This study tests whether immunoadsorption works as well as plasma exchange to improve symptoms in people with Guillain-Barré syndrome. The goal is to find which treatment helps recovery and is safer for patients.
Ulm, Baden-WurttembergAges 18 years+ - NCT06845865Recruiting
Gut barrier test in ICU patients with organ failure
This study looks at how the gut barrier works in people with severe infections that cause organ failure. It measures intestinal permeability using a simple test, to see if a 'leaky gut' contributes to how sick patients get.
VincennesAges 18 years+ - NCT07630779RecruitingPhase 3
Alpha Lipoic Acid and Myo-Inositol for PCOS Without Diabetes
This study tests whether two natural supplements—alpha lipoic acid and myo-inositol—can help manage PCOS symptoms in women without diabetes. The trial aims to see if this combination improves insulin sensitivity and ovulation.
Cairo, Cairo GovernorateAges 21–40 - NCT06865222Recruiting
Magnetic brain stimulation for lingering COVID symptoms
This study tests whether a special type of magnetic stimulation (called TMS) can help with lingering symptoms after COVID-19, such as loss of smell, ringing in the ears, or fatigue. The treatment is safe and non-invasive, using a magnet placed near your head.
Rochester, MinnesotaAges 18–65 - NCT06045351RecruitingPhase 1
Vitamin D shots for women with PCOS and low vitamin D
This trial tests whether vitamin D injections can help females with polycystic ovary syndrome (PCOS) who also have low vitamin D levels. Participants will receive the injection and be monitored for changes in their condition.
Karachi, SindhAges 18–45 - NCT07093905Recruiting
Comparing two anesthetics for rotator cuff repair surgery
This study compares two types of anesthesia (numbing medicine) for rotator cuff repair surgery. It will help find which method works better for pain control and recovery.
MarseilleAges 18 years+ - NCT07090473Recruiting
Electrical stimulation for recent spinal cord injury recovery
This trial tests whether a mild electrical stimulation (called TENS) can help recovery after a recent spinal cord injury. It is for people who are already in the ICU with a drain in their lower back and had a blunt injury within the past 12 hours.
San Francisco, CaliforniaAges 21 years+ - NCT03430037Enrolling by invitationPhase 2
Fisetin study to reduce frailty and inflammation in older women
This Phase 2 trial tests whether fisetin, a supplement, can reduce frailty and inflammation in postmenopausal women age 70 and older. If it works, it may help older adults feel stronger and have healthier body signals related to aging and inflammation.
Rochester, MinnesotaAges 70 years+ - NCT05905926Enrolling by invitationPhase 3
Tenapanor safety study for teens with constipation-predominant IBS
This trial checks the safety of tenapanor in children and teens (ages 6 to under 18) with IBS-C. It is only for people who finished a previous related study and agreed to continue follow-up.
Foley, AlabamaAges 6–18 - NCT07278570Recruiting
Tracking muscle stiffness with MRI during hands-on therapy for low back pain
This study uses a special MRI scan to see if hands-on therapy (manual therapy) helps reduce muscle stiffness and pain in people with chronic low back pain. It aims to find a better way to measure how well this treatment works.
Rochester, MinnesotaAges 18 years+ - NCT06985524Enrolling by invitation
Chinese medicine formula for stomach fullness and discomfort
This trial tests a traditional Chinese medicine formula (Weipi Formula) for people with a feeling of fullness or discomfort in the upper stomach after eating, known as epigastric stuffiness or functional dyspepsia. It aims to see if the herbal mix can improve symptoms.
Nanchang, JiangxiAges 18–80 - NCT06961136Recruiting
Herbal medicine for recovery after heart bypass surgery
This trial tests if a traditional Chinese herbal formula (Fuzheng Yangxin Prescription) can help people recover faster after coronary artery bypass surgery. It is for people who have a specific pattern of symptoms (called Qi-Yin deficiency) after their operation.
Beijing, Beijing MunicipalityAges 25–85 - NCT05654922RecruitingPhase 3
Prevent lung transplant airways scarring with ARINA-1
This Phase 3 trial tests ARINA-1 to slow or prevent worsening lung transplant scarring in the breathing tubes (bronchiolitis obliterans). It may help people who are showing early decline in lung function but are not yet at advanced disease.
Phoenix, ArizonaAges 18–75 - NCT05767658Recruiting
Online messages to support safer infant care
This study tests whether online social network posts and text messages can help pregnant people practice safer infant care after birth. It may help you feel more prepared about feeding and safe sleep.
Boston, MassachusettsAges Any age - NCT06932328RecruitingPhase 2
Granules for acute sore throat with wind-heat pattern
This trial tests whether Qinqiao Yan Shu Granules can help adults with acute pharyngitis (sore throat) that started within 48 hours. You must have a specific pattern called wind-heat invading the exterior, and at least moderate throat pain.
Harbin, HeilongjiangAges 18–65 - NCT06908200Recruiting
Radiofrequency for chronic pelvic pain with myofascial syndrome
This trial compares radiofrequency treatment, myofascial therapy, and no treatment to see which is most effective for women with chronic pelvic pain caused by tight or tender pelvic floor muscles. It aims to help reduce pain and improve quality of life.
BarcelonaAges 18 years+ - NCT06892041Recruiting
MRI study for jaw muscle pain
This trial uses a special MRI scan to measure jaw muscle pain. It aims to better understand this condition and may help improve future treatments.
New York, New YorkAges 18–65 - NCT05925504RecruitingPhase 2
Lowering luspatercept dose for lower-risk myelodysplastic anemia
This Phase 2 study tests whether gradually lowering the dose of luspatercept can help people with lower-risk myelodysplastic syndromes (MDS) who have anemia. It may help reduce side effects while still improving blood counts or symptoms.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06283498Enrolling by invitation
Radiofrequency treatment for overactive bladder
This study tests a new non-surgical treatment for overactive bladder using radiofrequency energy delivered through the vagina to calm the nerves that cause urgency and leaking. It is for people who have urge incontinence and have not found relief from medication.
Corona del Mar, CaliforniaAges 21–80 - NCT06758986Enrolling by invitation
Gender and shoulder pain study
This study looks at whether gender affects shoulder pain from subacromial impingement. It may help tailor future treatments.
Kırşehir, MerkezAges 18–65 - NCT06247046RecruitingPhase 3
Probiotic powder for IBS-D (SK08) trial
This study tests a new probiotic powder (SK08) to see if it reduces belly pain and diarrhea in people with IBS-D (irritable bowel syndrome with diarrhea). It lasts several months and involves taking the study powder twice a day.
Wuxi, JiangsuAges 18–70 - NCT06829940Recruiting
Baduanjin exercise for long COVID fatigue
This trial tests whether Baduanjin, a gentle mind-body exercise, can help people under 50 with long-standing chronic fatigue that's worse after COVID-19. It aims to see if this safe, low-impact practice improves energy and daily life without needing extra treatments.
CairoAges 18–50 - NCT06732765Recruiting
Eloda with or without muscle energy for back pain relief
This trial tests whether adding a muscle relaxation technique to Eloda treatment helps people with lower back pain caused by a tight muscle near the hip. It aims to find a more effective way to reduce pain and improve movement.
Sialkot, Punjab ProvinceAges 18–45 - NCT07432490RecruitingPhase 2
Fucose supplement trial for GLUT1 deficiency
This trial tests whether taking fucose (a type of sugar) can help people with GLUT1 deficiency syndrome, a rare genetic condition that affects how the brain gets energy. If you have ataxia (trouble with balance or coordination) and meet other criteria, this study may be an option for you.
Portland, OregonAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,201 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.