Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06652087Recruiting
Testing rifaximin for heart failure with preserved pumping
This trial tests whether the antibiotic rifaximin (taken by mouth) can improve heart function in people with a type of heart failure where the heart pumps well but is still weak (HFpEF). Rifaximin might help by changing the bacteria in your gut.
MoscowAges 18–80 - NCT04587856Recruiting
Study why blood cancer returns after donor stem cell transplant
This study looks at why a bone marrow disorder (MDS) can come back after a donor stem cell transplant. It may help researchers understand relapse, which could improve future care for people getting transplants.
BariAges 18 years+ - NCT07691047Recruiting
Venetoclax combination safety check for CLL patients
This study looks at a potential side effect called hemolytic syndrome (where the body destroys its own red blood cells) in patients with chronic lymphocytic leukemia (CLL) who are treated with a drug called venetoclax combined with another therapy. It aims to make sure this treatment is safe and to better understand the risk.
AmiensAges 18 years+ - NCT07695298RecruitingPhase 4
Testing faricimab for a rare eye disease linked to histoplasmosis
This trial tests a drug called faricimab (brand name Vabysmo) for treating abnormal blood vessel growth in the back of the eye, caused by a past infection with histoplasmosis. The goal is to see if it helps improve vision over 52 weeks.
Cincinnati, OhioAges 18 years+ - NCT07694882Recruiting
Gentle pressure techniques for chronic neck pain
This study tests two different types of gentle pressure techniques (myofascial release) to see which one helps relieve long-term neck pain and improve everyday function. It is for people with chronic neck pain that isn't caused by a specific injury or disease.
Famagusta, HatayAges 18–45 - NCT05574153Recruiting
Testing heart oxygen reserve in metabolic syndrome and healthy adults
This study measures how much oxygen your heart can use during stress and at rest using an MRI scan. It compares people with metabolic syndrome (a cluster of health risks) to people without those risks, to understand differences in heart function.
Montreal, QuebecAges 18–80 - NCT05936840Recruiting
Track menstrual cycles with a new monitoring method
This study uses regular testing (including ultrasounds) to monitor menstrual patterns across multiple cycles. It may help people understand and predict menstrual and ovulation-related changes, especially in people with PCOS or those who are athletes.
Calgary, AlbertaAges 18–55 - NCT07685639Recruiting
HEART ATTACK: A study to improve cholesterol care after a heart attack
This trial tests whether a program that uses electronic health records can help people who have had a heart attack lower their LDL (bad) cholesterol more effectively. It aims to improve follow-up care and reduce the risk of future heart problems.
Edmonton, AlbertaAges Any age - NCT07686315Recruiting
Safer breathing with advanced monitoring on a ventilator
This trial is testing a new way to monitor your breathing while you are on a ventilator, to make it safer. It is for people who need a ventilator for reasons other than lung failure, like after a coma, injury, or severe infection.
Milan, LombardyAges 18 years+ - NCT07688694Enrolling by invitation
Testing a legume-based supplement for blood sugar control
This study tests a supplement made from legume seed coats that may help control blood sugar. It is open to healthy adults, people at risk for diabetes, or those already diagnosed with type 2 diabetes.
Mysore, KarnatakaAges 20–60 - NCT07688044Recruiting
How food and bacteria cause belly pain in IBS
This study looks at how certain foods and gut bacteria might trigger abdominal pain in people with Irritable Bowel Syndrome (IBS). If you have IBS and frequent belly pain, you may help researchers understand the link between diet, bacteria, and pain.
Kingston, OntarioAges 18–70 - NCT07686601Enrolling by invitation
Shockwave therapy for belly fat
This study tests whether a sound-wave device (shockwave therapy) applied to your belly can help shrink fat and improve body measurements. It is for adults who have stubborn belly fat and are otherwise healthy.
Shibīn al Kawm, MenofyiaAges 18 years+ - NCT07682090Recruiting
Nerve stimulation for fibromyalgia pain
This study tests a gentle nerve stimulation device worn near your ear to see if it can reduce fibromyalgia pain and improve how your body handles stress. It is a non-invasive treatment option that you receive while continuing your regular medications.
Rome, LazioAges 18–70 - NCT07680868Recruiting
Caris Chromoseq data collection for blood cancers
This study collects data from a special genetic test called Caris Chromoseq for people with certain blood cancers. It aims to learn more about these diseases and possibly guide better treatments.
Phoenix, ArizonaAges 18 years+ - NCT04561557RecruitingEarly Phase 1
Cell therapy for relapsing nervous system autoimmune diseases
This early-phase trial tests CT103A “CAR-T” cell therapy to treat certain relapsing or treatment-resistant autoimmune diseases that affect the nervous system. It aims to see whether the cells are safe and may help reduce disease activity when standard treatments haven’t controlled symptoms.
Wuhan, HubeiAges 18–75 - NCT06502795Recruiting
Quad Strengthening for Knee Pain at Different Angles
This study tests whether strengthening your quadriceps (front thigh muscles) at different knee angles can reduce pain behind or around your kneecap. If you have had this type of knee pain for at least 3 months, you may be eligible.
Fortaleza, CearáAges 18–35 - NCT06665867Recruiting
Video Follow-Up for Kids With Stomach Pain
This trial tests whether video consultations (video calls) are a good option for follow-up appointments in children with functional abdominal pain disorders. It aims to make check-ups easier for families.
AmsterdamAges 4–17 - NCT07675304RecruitingEarly Phase 1
Mesotherapy for chronic low back pain study
This trial tests whether injecting a natural substance (collagen) into the lower back can safely reduce chronic pain. It may help people with pain that hasn't spread to the legs.
WarsawAges 18–65 - NCT07675265Recruiting
ARDS biomarker study
This study is for patients in the ICU with ARDS (a severe lung condition). It looks at biomarkers (special substances in your blood) to help understand different types of ARDS. You do not receive any treatment, but you help researchers learn more about the disease.
Urbana, IllinoisAges 18 years+ - NCT07679074Recruiting
Samphire guided care program for women's mood and brain fog
This 12-week program tests a mobile app and gentle brain stimulation device designed to help women manage mood and thinking problems linked to their menstrual cycle, perimenopause, or menopause. It aims to improve day-to-day well-being, work productivity, and overall quality of life.
San Francisco, CaliforniaAges 18–65 - NCT07674043Recruiting
Pressure monitoring for teen shinbone fractures
This study tests a device that monitors muscle pressure after surgery for a broken shinbone (tibia). The goal is to help doctors detect a dangerous condition called compartment syndrome early, so they can treat it quickly.
Boston, MassachusettsAges 10–21 - NCT07675655Recruiting
Mulligan vs. PNF exercises for shoulder pain
This trial compares two hands-on therapy techniques for people with shoulder impingement (pain when lifting the arm). It tests if one method works better for reducing pain and improving movement.
Sohag, TahtaAges 20–40 - NCT07671898Recruiting
Freezing vs. Radiofrequency for Slow Heart Rate
This trial compares two procedures to treat very slow heart rates without needing a pacemaker. One uses freezing (cryoablation) and the other uses radiofrequency energy to target nerves that control heart rate.
Tomsk, Tomsk OblastAges 18–60 - NCT07673250Enrolling by invitation
Personalized breathing settings for ECMO patients
This study tests whether personalized breathing machine settings can improve outcomes for people on ECMO (a heart-lung support machine). It is designed for patients who have had or are waiting for a lung or heart transplant.
La Jolla, CaliforniaAges 18 years+
Hear when a new Down Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.