Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06308965Recruiting
Does blood vessel-sparing hip replacement improve recovery?
This study compares two different surgical techniques for total hip replacement using an anterior approach. The goal is to see if saving the small blood vessels around the hip during surgery leads to a better recovery for patients.
Genk, LimburgAges 18 years+ - NCT06034275RecruitingPhase 1
Study of VIP943 for CD123-positive blood cancers
This trial tests a new drug called VIP943 for people with advanced acute myeloid leukemia (AML), B-cell acute lymphoblastic leukemia (B-ALL), or myelodysplastic syndrome (MDS) whose cancer cells have a marker called CD123. It is for those who have tried all other treatments or cannot receive them.
Birmingham, AlabamaAges 18 years+ - NCT06551961Recruiting
How two fibers affect your gut health
This study tests how two types of fiber (inulin and methylcellulose) affect your gut when eaten regularly. You'll eat provided meals and have your breath tested to see how your gut breaks down the fiber.
Nottingham, NottinghamshireAges 18–65 - NCT06691555Recruiting
Long-term safety of a silicone tube eye implant
This study follows up with people who have previously received a special silicone tube implant in their eye to see how they are doing over time. It aims to check the long-term safety and how well the implant is working.
TbilisiAges 40–90 - NCT07638241Recruiting
AI-Powered Personalized Diet Management Study
This study tests a new AI-powered app that gives you personalized dietary recommendations based on your health. You'll use your smartphone to get daily dietary guidance and track how it affects your health over time.
Seoul, SeoulAges 20–90 - NCT07639060Recruiting
Pain Relief Study Using Freezing Nerve Treatment
This study watches how well a freezing procedure works for chronic pain over 6 to 12 months. Your doctor thinks this procedure could help your pain, and the study simply tracks your recovery through questionnaires to help doctors understand if it works.
Old Saybrook, ConnecticutAges 18 years+ - NCT07644715Recruiting
AI Analysis of Heart Rhythms and Immune-Related Heart Damage
This study uses artificial intelligence to analyze heart electrical recordings (ECGs) from existing patient databases to better detect dangerous heart rhythm problems and heart inflammation caused by cancer immunotherapy. Researchers are not giving any new treatments—they're studying existing data to improve diagnosis.
ParisAges Any age - NCT06381414Recruiting
Childhood early oral aging: causes and effects on teeth
This study looks at why some young children have early signs of oral aging and how it affects their bite. It aims to find the causes and possible consequences for kids ages 3 to 6.
São Paulo, São PauloAges 3–6 - NCT05924100RecruitingPhase 2
Luspatercept for lower red blood counts in MDS with del5q
This Phase 2 trial studies luspatercept to improve anemia (low red blood cells) in people with MDS that has a del5q change. It also checks safety, especially for people who need red blood cell transfusions and have not benefited from prior standard treatments.
AlessandriaAges 18 years+ - NCT05406570Recruiting
Personalized breathing settings for adults with severe ARDS
This trial tests a more tailored way to set the amount of air delivered by a ventilator in people with severe ARDS. The goal is to see if personalized breathing settings can improve breathing and heart-related monitoring while patients are in intensive care.
LyonAges 18 years+ - NCT07630779RecruitingPhase 3
Alpha Lipoic Acid and Myo-Inositol for PCOS Without Diabetes
This study tests whether two natural supplements—alpha lipoic acid and myo-inositol—can help manage PCOS symptoms in women without diabetes. The trial aims to see if this combination improves insulin sensitivity and ovulation.
Cairo, Cairo GovernorateAges 21–40 - NCT07633366Recruiting
Understanding ARDS Through Lung Fluid and Imaging Analysis
This study examines lung fluid samples and imaging scans from patients on breathing machines to better understand acute respiratory distress syndrome (ARDS), a serious lung condition. Researchers hope this will help doctors diagnose and treat ARDS more effectively in the future.
Vienna, State of ViennaAges 18 years+ - NCT07632196Recruiting
Nerve Stimulation to Improve Bowel Control After Rectal Cancer Surgery
This trial tests whether a small electrical device placed on the skin behind your ankle can help improve bowel control after surgery to remove rectal cancer. Many patients experience changes in bowel function after this surgery, and this treatment may help restore normal continence.
Manresa, BarcelonaAges 18 years+ - NCT06662630Recruiting
Oscillatory ventilation study for ICU patients on breathing machines
This study tests a new breathing method (high-frequency oscillatory ventilation) for patients in the ICU who need a breathing tube. It looks at how safe it is and how it affects the body, and is for people with certain lung problems like ARDS or collapsed lungs.
Shanghai, Shanghai MunicipalityAges 20–90 - NCT07622589Enrolling by invitation
How stress affects your body during market and news volatility
This study tracks how financial market changes, work stress, and news exposure affect your body's stress response using a wearable device and smartphone app. Researchers want to understand the connection between stress and physical health markers during uncertain times.
New York, New YorkAges 18 years+ - NCT07620925Recruiting
Aortic Valve Calcium Score Study Using Heart Ultrasound
This study develops and tests a new way to diagnose severe aortic stenosis (narrowing of the aortic valve) by measuring calcium buildup on the valve using heart ultrasound. If you're already getting both an ultrasound and a CT scan of your heart, this study compares how well the ultrasound method can identify severe stenosis.
BolognaAges 18 years+ - NCT07623590Recruiting
Finding the Best Lung Pressure Settings in Critically Ill Patients
This study tests two different methods to help doctors adjust breathing machine settings for patients with severe lung injury. The trial compares gentle chest/belly compressions with a special imaging technique to find the safest pressure levels.
CréteilAges 18 years+ - NCT07624136Recruiting
Kinesio Taping for Shoulder Flexibility and Range of Motion
This study tests whether a special athletic tape (Kinesio tape) applied to your lower back and shoulder area can improve flexibility and reduce shoulder pain in people with chronic shoulder impingement syndrome—a condition where shoulder structures get pinched, causing long-term pain and stiffness.
Ankara, AltindagAges 20–40 - NCT06652750Recruiting
5G cloud-based check-up for heart device patients
This study tests whether a 5G-based remote check-up (over the cloud) is safe and effective for people with certain implanted heart devices, like pacemakers. You'll skip your first clinic visit and instead use a video call or remote check to see how your device is doing.
Guangzhou, GuangdongAges 18 years+ - NCT06450301Recruiting
Studying aging cells in thin uterine lining
This study is looking at aging cells in the lining of the uterus in women who have a thin endometrial lining. It aims to understand what causes this problem and how to improve fertility treatment.
Toronto, OntarioAges 18–39 - NCT06195267Recruiting
Sivelestat for lung protection during emergency aortic surgery
This study tests whether a drug called sivelestat can protect your lungs and other organs during emergency surgery for a very serious aortic tear. If you qualify, you would receive the drug or a placebo right before and after surgery.
BeijingAges 18–90 - NCT06360302Recruiting
Exercise and insulin resistance in dialysis patients
This study looks at how exercise affects muscle metabolism and insulin resistance in people on dialysis, compared to those with metabolic syndrome and healthy individuals. It aims to find blood markers that could help assess insulin resistance in dialysis patients.
MontpellierAges 40–75 - NCT06222866Recruiting
Blood thinner and inflammation monitoring after heart procedures
This study looks at how well blood thinners (anticoagulants) and inflammation markers work in people having heart or blood vessel procedures. It aims to better monitor these treatments to improve patient safety.
Innsbruck, TyrolAges 18 years+ - NCT06612944RecruitingPhase 2
Preventing relapse after stem cell transplant for high-risk MDS
This trial tests whether giving medication after a donor stem cell transplant can prevent the return of very high-risk myelodysplastic syndrome (MDS). It is for people who have a suitable donor and are healthy enough for the procedure.
ShanghaiAges 18–70
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.