Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,201 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06721312Recruiting
Heart rate tracking for doctor stress
This study uses a smartphone app to track your heart rate changes over time. It aims to understand how doctors' stress and recovery patterns relate to their well-being, resilience, and burnout.
AberdeenAges Any age - NCT07276035Recruiting
Brain-stomach circuits in chronic nausea
This study looks at how the brain and stomach communicate in people with chronic nausea. It uses a noninvasive brain stimulation method called TMS to understand brain activity. You may qualify if you have chronic nausea or are a healthy volunteer.
Pittsburgh, PennsylvaniaAges 21–60 - NCT07006025RecruitingPhase 1
Oral THU-decitabine for MDS that has returned or not improved
This trial tests an oral combination of two drugs (THU and decitabine) for people with myelodysplastic syndromes (MDS) whose disease has come back or not responded to at least one prior standard treatment. The goal is to see if it can help control the disease.
The Bronx, New YorkAges 18 years+ - NCT06644222Recruiting
Physical therapy exercises for smartphone-related shoulder problems
This study tests if two types of physical therapy exercises can improve shoulder posture in young women who have rounded shoulders from using smartphones. It aims to find which treatment works better.
Al Majma'ah, AlriyadhAges 18–25 - NCT07310485Enrolling by invitation
Phytoestrogens for premenstrual syndrome in women nearing menopause
This trial tests whether plant-based compounds (phytoestrogens) can help reduce premenstrual syndrome symptoms in women aged 40–55. It also looks at how these supplements affect gene activity.
Amman, Amman GovernorateAges 40–55 - NCT06573450Recruiting
Breath test study for allergic rhinitis and asthma
This study is looking at certain substances in your breath to better understand allergic rhinitis, asthma, and the combination of both (CARAS). It could help doctors find new ways to diagnose or treat these conditions.
Henan, ZhengzhouAges 18–80 - NCT07396480RecruitingPhase 3
Add-on Venetoclax before stem cell transplant for AML/MDS
This trial tests adding venetoclax to the usual chemotherapy (fludarabine and melphalan) given before a stem cell transplant for older adults with AML or MDS. The goal is to see if the combination helps prevent the disease from coming back after transplant.
Fuzhou, FujianAges 50–75 - NCT06552052Recruiting
Natural history study of genetic blood vessel disease
This study tracks the health of people with a confirmed ACTA2 gene change over time to better understand the disease. It may help researchers learn how to improve care for this condition.
Boston, MassachusettsAges 4 weeks+ - NCT06527183Recruiting
Fibromyalgia and small fiber nerve study
This study looks at whether people with fibromyalgia or long-term chronic pain have damage to the small nerve fibers in their skin. Understanding this could help develop better treatments.
Boulogne-BillancourtAges 18 years+ - NCT06519617Enrolling by invitationPhase 2
Combined Chinese and Western medicine for Sjögren's gland damage
This trial tests whether adding traditional Chinese medicine to standard care can help repair gland damage caused by Sjögren's syndrome. It is for people with primary Sjögren's who have a specific traditional Chinese medicine pattern called 'qi and yin deficiency'.
Beijing, Beijing MunicipalityAges 18–75 - NCT02889016Recruiting
Markers study for children with PANS and healthy controls
This study looks at physical, immune, and brain-related “markers” in children with PANS and compares them with healthy children. It may help doctors understand what is happening in PANS and how to recognize it more clearly early on.
Palo Alto, CaliforniaAges 4–18 - NCT05566496Recruiting
MRI study of different tic disorder types
This study uses MRI (a type of body scan) to look at differences between types of tic disorders in children. It may help doctors better understand what’s happening in conditions like Tourette syndrome and chronic tic disorders.
TaipeiAges birth–18 years - NCT07694882Recruiting
Gentle pressure techniques for chronic neck pain
This study tests two different types of gentle pressure techniques (myofascial release) to see which one helps relieve long-term neck pain and improve everyday function. It is for people with chronic neck pain that isn't caused by a specific injury or disease.
Famagusta, HatayAges 18–45 - NCT06481072Recruiting
Digital therapy for kids with chronic stomach pain
This trial tests a digital (online) therapy program to help children with chronic stomach pain. It's designed for kids ages 8 to 14 who have been diagnosed with a functional abdominal pain disorder and can use a computer or tablet at home.
GothenburgAges 8–14 - NCT06418217Recruiting
Exercise and education for lateral hip pain
This study tests whether exercise and patient education can help people with long-term lateral hip pain (pain on the outside of the hip). If you've had hip pain for over 6 months and an MRI confirms the cause, you may be able to join.
Horsens, HorsensAges 18–75 - NCT06432816Recruiting
Nano therapy for menopausal hot flashes and night sweats
This study tests a new nano-therapy to see if it can reduce hot flashes and night sweats in women going through menopause. It may be a good option if you haven't tried other treatments and are looking for a non-hormonal approach.
Toluca, State of MexicoAges 45–55 - NCT06425978RecruitingPhase 4
Non-hormonal gel for vaginal dryness in menopause
This study tests a non-hormonal gel (called cellular matrix) to see if it helps with vaginal dryness and discomfort caused by menopause. It is for women who have these symptoms and want a treatment without hormones.
BarcelonaAges 18–70 - NCT07675304RecruitingEarly Phase 1
Mesotherapy for chronic low back pain study
This trial tests whether injecting a natural substance (collagen) into the lower back can safely reduce chronic pain. It may help people with pain that hasn't spread to the legs.
WarsawAges 18–65 - NCT06377462Recruiting
VEXAS syndrome registry with blood sample collection
This study creates a national registry for people with VEXAS syndrome to track the disease and collect blood samples for research. Joining helps doctors learn more about VEXAS so they can better diagnose and treat it in the future.
AachenAges 18 years+ - NCT06373341Recruiting
Virtual reality rehab for arm and hand after ICU stay
This study tests whether using virtual reality (VR) games can help you regain movement and strength in your arms and hands after a long hospital stay in the ICU. It is designed for people who live in the Frisian region of the Netherlands and can understand Dutch.
Leeuwarden, Provincie FrieslandAges 18 years+ - NCT07208058RecruitingPhase 3
Testing plonmarlimab for blood cell overactivation in people with rheumatic disease
This trial tests a new drug called plonmarlimab for people with a rheumatic (joint or immune) disease who also have a dangerous overreaction of their immune system called HLH (or MAS). The goal is to see if the drug can help when high-dose steroids have not worked or are not an option.
Beijing, Beijing MunicipalityAges 16–80 - NCT06482671RecruitingPhase 3
Rikkunshito for newly diagnosed functional dyspepsia
This trial tests a herbal medicine called rikkunshito for people newly diagnosed with functional dyspepsia (stomach pain or discomfort). It aims to see if the treatment can improve symptoms in adults who fit certain health requirements.
Leuven, Vlaams-BrabantAges 18 years+ - NCT06197724Recruiting
MCG test for chest pain patients scheduled for heart scans
This trial is testing a new magnetic heart scan (MCG) to see if it can better detect blockages in people with chest pain that is not a full heart attack. If you are having chest pain and are already scheduled for a heart catheterization or CT scan, this study might help find the cause more accurately.
Jinan, ShandongAges 18 years+ - NCT07737093Recruiting
Comparing two breathing devices after lung surgery
This trial compares two handheld devices (Acapella and Flutter) to see which works better at helping you clear mucus and improve your breathing after lung lobe removal surgery.
Lahore, Punjab ProvinceAges 35–54
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,201 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.