Clinical trials
Drug Effect clinical trials
Below are recruiting drug effect clinical trials, each written for real people, not researchers. We’re tracking 156 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06328608RecruitingPhase 2/Phase 3
PRX-102 for children with Fabry disease
This study tests a new enzyme replacement therapy called PRX-102 for children with Fabry disease. It aims to see if the drug is safe and helps manage symptoms like pain and eye or skin changes.
Phoenix, ArizonaAges 2–17 - NCT06499363Recruiting
Treprostinil for pulmonary hypertension in newborns
This study collects information on how well a medicine called treprostinil works and how safe it is for newborn babies with pulmonary hypertension (high blood pressure in the lungs). It is for babies who have already received this treatment as part of their regular care.
BronAges Up to 10 months - NCT06917482RecruitingPhase 1
Testing a new drug called BW-40202 in healthy people
This study tests a new medicine called BW-40202 for the first time in people. It is for healthy volunteers to see if the drug is safe and how it works in the body. You must be in good general health to take part.
Brisbane, QueenslandAges 18–60 - NCT07163182RecruitingPhase 1
Safety study of nasal CHF6467 in healthy volunteers
This study tests a new medicine called CHF6467 given as a nasal spray. It looks at how safe the medicine is, how it is absorbed and removed from the body, and what side effects it might cause. Healthy volunteers aged 18 to 55 can take part.
SofiaAges 18–55 - NCT07559903Recruiting
Drug-coated balloon heart artery treatment registry
This study tracks outcomes in adults who receive a special balloon catheter (coated with medication) to open blocked heart arteries. Researchers collect data to understand how well this treatment works and any side effects that occur.
Phoenix, ArizonaAges 18 years+ - NCT06959524Recruiting
AGENT balloon for new heart artery blockages
This trial tests a drug-coated balloon (AGENT DCB) versus standard angioplasty/stenting for new blockages in heart arteries. It aims to see if the coated balloon works better and is safe for people who haven't had prior stents in that spot.
La Jolla, CaliforniaAges 18 years+ - NCT06883487Recruiting
Exploring HER2 testing in high-grade ovarian cancer
This study looks at how to best detect the HER2 protein in high-grade serous ovarian cancer. The goal is to improve treatment choices for people with this type of cancer.
Guangzhou, GuangdongAges 18–75 - NCT06447168Recruiting
Observing elafibranor in everyday care for PBC
This study follows people with primary biliary cholangitis (PBC) who are already taking or starting elafibranor, to see how well it works and how safe it is in everyday life. No extra treatments or tests are required beyond what your doctor normally does.
Coronado, CaliforniaAges Any age - NCT03713424RecruitingPhase 2
Brain scan study of an antibiotic for drug addiction
This study uses an MRI brain scan to see how taking clavulanic acid affects brain activity related to drug addiction. It may help researchers understand whether this medicine could change how addiction-related cues affect the brain.
Columbia, MissouriAges 18–65 - NCT06696573Recruiting
Anti-inflammatory drugs for pain during medical abortion
This study tests whether giving anti-inflammatory drugs before or during a medical abortion (13–22 weeks) can help prevent pain better than treating pain once it starts. If you're eligible, taking part may help improve pain management for future patients.
Ho Chi Minh CityAges 18 years+ - NCT07147231RecruitingPhase 1/Phase 2
Pidnarulex plus cemiplimab for MSS colorectal cancer
This trial tests two drugs together: pidnarulex (a targeted therapy) and cemiplimab (an immunotherapy that helps your immune system fight cancer). It is for people with advanced colorectal cancer that is microsatellite stable (MSS) and has not responded to current treatments, especially if their tumor has a MYC or FBXW7 change.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06977724RecruitingPhase 1
Testing a new drug for lupus, sjogren's, and rheumatoid arthritis
This study tests an experimental medicine given by IV infusion to see if it is safe and helps reduce symptoms of lupus, sjogren's disease, or rheumatoid arthritis. It is an early-phase trial, so the main goals are checking side effects and how the drug behaves in the body, but it will also look at how well it works.
Avon Park, FloridaAges 18–75 - NCT03425812Recruiting
NSAID medicines to prevent flares in spondyloarthritis after remission
This trial tests whether taking nonsteroidal anti-inflammatory drugs (NSAIDs) helps people with axial spondyloarthritis stay in remission and avoid future flare-ups. It’s meant to see if NSAIDs can reduce the chance of symptoms returning and keep disease activity low over time.
Xiamen, FujianAges 18 years+ - NCT07061951RecruitingPhase 2
Mirdametinib for relapsed or refractory CLL or SLL
This trial tests a drug called mirdametinib for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that has come back or not responded to at least two prior treatments, including a BTK inhibitor and a BCL2 inhibitor. The goal is to see if mirdametinib can help shrink the cancer or slow its growth.
Duarte, CaliforniaAges 18 years+ - NCT07607964RecruitingPhase 1
ABBV-519 Study for Lupus or Rheumatoid Arthritis
This early-stage trial tests a new drug called ABBV-519 given as infusions or injections to treat systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA) in adults whose disease hasn't responded well to other treatments. Researchers will measure how safe the drug is, how it moves through your body, and whether it helps reduce symptoms.
Anniston, AlabamaAges 18–75 - NCT00404989Recruiting
Pregnancy drug safety registry for people with HIV treatment
This trial is a pregnancy registry that collects information about birth outcomes when certain HIV medicines are taken during pregnancy. It helps detect any major birth defects so future pregnancies can be safer.
Wilmington, North CarolinaAges 12–60 - NCT07200830RecruitingPhase 3
Testing different schedules of a targeted radiation drug for advanced prostate cancer
This trial tests two different dosing schedules of a drug called Lutetium-177 PSMA RLT, which delivers radiation directly to prostate cancer cells. It is for men with advanced prostate cancer that has stopped responding to hormone therapy and has spread, who have not yet had chemotherapy for this stage of the disease.
Anchorage, AlaskaAges 18 years+ - NCT07035314Recruiting
Comparing medicines for pain after tonsil removal in children
This study compares two ways to manage pain after tonsil removal in children: a medication given by mouth or injection versus a medication applied directly to the surgical site. The goal is to find which approach works better for pain control.
CairoAges 4–10 - NCT06933056RecruitingEarly Phase 1
Comparing sotagliflozin to standard blood thinners for heart health
This study compares how well a diabetes drug, sotagliflozin, affects blood clotting compared to common blood thinners like aspirin and clopidogrel. It may help people at risk for heart problems find a safer or more effective treatment.
Ann Arbor, MichiganAges 18–79 - NCT06604728Recruiting
IV vs. shot biologics for IBD: which works better?
This study compares intravenous (IV) and under-the-skin (subcutaneous) biologic drugs for people with Crohn's disease or ulcerative colitis. It helps doctors understand if switching from the IV form to a shot is as effective and well-tolerated.
RomaAges 18 years+ - NCT06980870RecruitingPhase 2
Pain medicine before root canal for less discomfort
This study tests whether taking ibuprofen or dexamethasone before a root canal can help reduce pain afterward. It's for people with a painful, inflamed tooth nerve who haven't already taken pain medicine for it.
RawalpindiAges 18–50 - NCT07586618RecruitingPhase 1
New Drug 4A10 for Hard-to-Treat Lymphoblastic Leukemia or Lymphoma
This is an early-stage study testing a new experimental drug (4A10) in patients whose acute lymphoblastic leukemia or lymphoblastic lymphoma has returned or stopped responding to standard treatments. Researchers want to learn if the drug is safe and how it works in the body.
Aurora, ColoradoAges 18 years+ - NCT05350332Recruiting
Testing how lung air volume affects airway narrowing during sleep testing
This study looks at whether changing lung air volume affects how open or blocked your upper airway is during a drug-induced sleep test (DISE). It may help guide surgical choices for people with obstructive sleep apnea (OSA).
Atlanta, GeorgiaAges 18 years+ - NCT05691491RecruitingPhase 1/Phase 2
Temozolomide plus M1774 for advanced metastatic cancers
This Phase 1/2 trial tests a combination of temozolomide and M1774 to see how safe it is and whether it can help shrink advanced cancers that have spread. It focuses on certain tumor types and specific biomarker results, and it may be an option if standard treatments have been tried or aren’t possible.
Irvine, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for drug effect?
- Yes. Clin2 currently lists 156 recruiting drug effect studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a drug effect trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a drug effect trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.