Clinical trials
Drug Abuse clinical trials
Below are recruiting drug abuse clinical trials, each written for real people, not researchers. We’re tracking 39 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02299921Recruiting
Alcohol and drug effects on immunity in ICU breathing patients
This study looks at how alcohol and other drugs can affect the body’s immune system in people who are very sick in the ICU due to breathing problems. It may help doctors better understand immune changes during critical illness and respiratory failure.
Aurora, ColoradoAges 18–90 - NCT01036581Recruiting
Brain MRI study to improve brain imaging for drug research
This study uses advanced MRI brain scans to better show how the brain responds to medicines (drug-related effects). You may also do extra safety screening and non-invasive brain stimulation for some parts of the research.
Baltimore, MarylandAges 18–80 - NCT04141202Recruiting
Exercise program during short inpatient treatment for substance use
This trial tests a structured exercise program for people receiving short-term inpatient treatment for substance use. It may help improve health and recovery support during your stay.
TrondheimAges 18 years+ - NCT05679284Recruiting
Study for retained needle fragments in people who inject drugs
This observational study looks at whether small pieces of drug-injection needles remain in injection sites. You may help by answering a questionnaire and getting X-ray images, which could improve how care and safety are handled for people who inject drugs.
TampereAges 18 years+ - NCT05067387RecruitingPhase 1
Oral THC and CBD for occasional cannabis users
This early (Phase 1) study tests how an oral THC and CBD product affects the body in healthy adults who use cannabis only rarely. It may help researchers understand safety and effects before larger studies.
Los Angeles, CaliforniaAges 21–55 - NCT07466784Recruiting
Opioid use registry for emergency patients
This study is for people who come to the emergency department because of an opioid overdose, withdrawal, or related problem. It will collect information about patients' experiences to help improve care and support for opioid use.
Vancouver, British ColumbiaAges Any age - NCT07650136Recruiting
Testing a New Fingerprint-Based Drug Screening Method
This study compares a new fingerprint-based drug screening system to standard methods. Healthy volunteers will participate to help verify that the new fingerprint test works accurately for detecting drugs.
Marlton, New JerseyAges 18–65 - NCT07456579Enrolling by invitation
Alcohol and cannabis use in pregnancy
This study looks at alcohol and cannabis use during pregnancy by asking new mothers about their habits and testing newborn stool samples (meconium). The goal is to understand how common these substances are among pregnant women in Slovenia and how they might affect babies.
LjubljanaAges Any age - NCT07340554Recruiting
Brain imaging study for teens who use cannabis
This study looks at the brains of teenagers who use cannabis using an MRI scanner. It aims to understand how cannabis affects the developing brain, which might help improve treatment options.
Indianapolis, IndianaAges 14–17 - NCT03745339Recruiting
Smell-based memory task in people with opioid-use disorder
This study tests how people learn and infer what something means using a smell-and-memory task. It compares people with opioid-use disorder who are abstinent, those in maintenance treatment, and healthy controls to see what affects learning and decision-making after opioid use.
Baltimore, MarylandAges 21–60 - NCT07064343Recruiting
Anti-drug adventure program for young students
This study tests an adventure-based program to help prevent drug use among college students. Participants take part in outdoor activities designed to build resilience and avoid substance abuse.
Hong KongAges 18–35 - NCT07541131Enrolling by invitation
Reducing HIV stigma to improve treatment access for drug users
This study tests whether reducing stigma and discrimination against people who use drugs can help more people access HIV treatment and prevention. You would participate in peer-led group sessions and surveys over 18 months to help researchers understand how stigma affects treatment access in Bishkek.
BishkekAges 18 years+ - NCT05361603Recruiting
Screening for hepatitis B, C, and HIV at the same time
This trial tests how acceptable it is for people who use services outside traditional clinics to be screened for hepatitis B, hepatitis C, and HIV during the same visit. If you join, you would be asked to participate and provide consent for the screening process.
Limoges, Haute VienneAges 18 years+ - NCT05918601Recruiting
Peer support program for drug recovery support
This program offers personalized support led by trained peers for people who have used drugs in the last year. You may be able to join as a participant if you meet the language, age, and recent drug-use criteria, or apply as a peer supporter if you have medical background and pass training.
Hong KongAges Any age - NCT06561828RecruitingEarly Phase 1
Brain stimulation study for learning and decision-making
This study uses a non-invasive brain stimulation technique called TMS (transcranial magnetic stimulation) to see if it can improve how people learn and make decisions. It is for healthy adults who are right-handed.
Baltimore, MarylandAges 18–45 - NCT06676059Recruiting
Substance use monitoring study with a smartphone app
This study uses a smartphone app and daily surveys to track alcohol or drug use. It aims to create a database for future research on addiction patterns and recovery.
Baltimore, MarylandAges 18–120 - NCT06860607RecruitingPhase 1
Environment and Alcohol: A Pilot Study
A pilot study exploring the interaction between environment and alcohol consumption in individuals with alcohol use disorder (AUD), using smartphone-based ecological momentary assessment (EMA).
Baltimore, MarylandAges 21–100 - NCT07637669Recruiting
Smell and decision-making in people with HIV and substance use
This study looks at how smell and decision-making are affected in people living with HIV and/or substance use disorders. You may join one of four groups based on your HIV status and substance use history, and you will complete smell tests and computer tasks, with an optional MRI.
Baltimore, MarylandAges 18–65 - NCT06995885Enrolling by invitation
A study to improve tracking of opioid use in the fentanyl era
This study aims to develop a better tool for recalling and tracking opioid use patterns, especially with fentanyl. It may help people who use opioids outside of medical settings to more accurately report their use.
Baltimore, MarylandAges 18–99 - NCT06859710RecruitingPhase 1
THC and CBD as a harm reduction strategy
This study looks at whether different types of cannabis (containing THC and/or CBD) might help people who use cannabis regularly reduce potential harms. You will be asked to take cannabis in a controlled setting and complete tasks and questionnaires.
Los Angeles, CaliforniaAges 21–55 - NCT06552741Recruiting
Screening for substance and alcohol use studies
This study screens people with or without past or current substance or alcohol use problems. It helps the researchers see if you might qualify for other studies at the NIDA research center.
Baltimore, MarylandAges 18–99 - NCT05865470RecruitingPhase 1
How age affects smoked and oral THC effects
This early-stage study compares how people in different age groups respond to THC taken by smoking versus by mouth. It aims to understand age-related differences in effects and safety, which could help guide safer use in the future.
Los Angeles, CaliforniaAges 18–65 - NCT05818384Recruiting
Health program for Choctaw youth to improve daily habits
This is a community health program for Choctaw Nation of Oklahoma youth that tries to improve habits related to food, movement, and screen time. It may help you build healthier routines for everyday life.
Durant, OklahomaAges 12–19 - NCT05807139RecruitingPhase 1
Spironolactone for alcohol use disorder
This Phase 1 study tests whether spironolactone (a medicine that affects salt and hormone balance) is safe and potentially helpful in people with alcohol use disorder. You may be eligible if you are currently drinking heavily, have low alcohol withdrawal symptoms, and meet several lab and medication safety rules.
Baltimore, MarylandAges 21–99
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Common questions
- Are there clinical trials for drug abuse?
- Yes. Clin2 currently lists 39 recruiting drug abuse studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a drug abuse trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a drug abuse trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.