Clinical trials
Drug Abuse clinical trials
Below are recruiting drug abuse clinical trials, each written for real people, not researchers. We’re tracking 37 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02299921Recruiting
Alcohol and drug effects on immunity in ICU breathing patients
This study looks at how alcohol and other drugs can affect the body’s immune system in people who are very sick in the ICU due to breathing problems. It may help doctors better understand immune changes during critical illness and respiratory failure.
Aurora, ColoradoAges 18–90 - NCT06194409Recruiting
Heart infection in drug users vs. non-users
This study looks at how infective endocarditis (a serious heart infection) differs between people who use intravenous drugs and those who do not. It aims to understand patterns, symptoms, and outcomes to help improve care.
AsyutAges 18 years+ - NCT01036581Recruiting
Brain MRI study to improve brain imaging for drug research
This study uses advanced MRI brain scans to better show how the brain responds to medicines (drug-related effects). You may also do extra safety screening and non-invasive brain stimulation for some parts of the research.
Baltimore, MarylandAges 18–80 - NCT04141202Recruiting
Exercise program during short inpatient treatment for substance use
This trial tests a structured exercise program for people receiving short-term inpatient treatment for substance use. It may help improve health and recovery support during your stay.
TrondheimAges 18 years+ - NCT05679284Recruiting
Study for retained needle fragments in people who inject drugs
This observational study looks at whether small pieces of drug-injection needles remain in injection sites. You may help by answering a questionnaire and getting X-ray images, which could improve how care and safety are handled for people who inject drugs.
TampereAges 18 years+ - NCT07466784Recruiting
Opioid use registry for emergency patients
This study is for people who come to the emergency department because of an opioid overdose, withdrawal, or related problem. It will collect information about patients' experiences to help improve care and support for opioid use.
Vancouver, British ColumbiaAges Any age - NCT07650136Recruiting
Testing a New Fingerprint-Based Drug Screening Method
This study compares a new fingerprint-based drug screening system to standard methods. Healthy volunteers will participate to help verify that the new fingerprint test works accurately for detecting drugs.
Marlton, New JerseyAges 18–65 - NCT07456579Enrolling by invitation
Alcohol and cannabis use in pregnancy
This study looks at alcohol and cannabis use during pregnancy by asking new mothers about their habits and testing newborn stool samples (meconium). The goal is to understand how common these substances are among pregnant women in Slovenia and how they might affect babies.
LjubljanaAges Any age - NCT07340554Recruiting
Brain imaging study for teens who use cannabis
This study looks at the brains of teenagers who use cannabis using an MRI scanner. It aims to understand how cannabis affects the developing brain, which might help improve treatment options.
Indianapolis, IndianaAges 14–17 - NCT03745339Recruiting
Smell-based memory task in people with opioid-use disorder
This study tests how people learn and infer what something means using a smell-and-memory task. It compares people with opioid-use disorder who are abstinent, those in maintenance treatment, and healthy controls to see what affects learning and decision-making after opioid use.
Baltimore, MarylandAges 21–60 - NCT07064343Recruiting
Anti-drug adventure program for young students
This study tests an adventure-based program to help prevent drug use among college students. Participants take part in outdoor activities designed to build resilience and avoid substance abuse.
Hong KongAges 18–35 - NCT07541131Enrolling by invitation
Reducing HIV stigma to improve treatment access for drug users
This study tests whether reducing stigma and discrimination against people who use drugs can help more people access HIV treatment and prevention. You would participate in peer-led group sessions and surveys over 18 months to help researchers understand how stigma affects treatment access in Bishkek.
BishkekAges 18 years+ - NCT05361603Recruiting
Screening for hepatitis B, C, and HIV at the same time
This trial tests how acceptable it is for people who use services outside traditional clinics to be screened for hepatitis B, hepatitis C, and HIV during the same visit. If you join, you would be asked to participate and provide consent for the screening process.
Limoges, Haute VienneAges 18 years+ - NCT05918601Recruiting
Peer support program for drug recovery support
This program offers personalized support led by trained peers for people who have used drugs in the last year. You may be able to join as a participant if you meet the language, age, and recent drug-use criteria, or apply as a peer supporter if you have medical background and pass training.
Hong KongAges Any age - NCT06860607RecruitingPhase 1
Environment and Alcohol: A Pilot Study
A pilot study exploring the interaction between environment and alcohol consumption in individuals with alcohol use disorder (AUD), using smartphone-based ecological momentary assessment (EMA).
Baltimore, MarylandAges 21–100 - NCT06561828RecruitingEarly Phase 1
Brain stimulation study for learning and decision-making
This study uses a non-invasive brain stimulation technique called TMS (transcranial magnetic stimulation) to see if it can improve how people learn and make decisions. It is for healthy adults who are right-handed.
Baltimore, MarylandAges 18–45 - NCT06995885Enrolling by invitation
A study to improve tracking of opioid use in the fentanyl era
This study aims to develop a better tool for recalling and tracking opioid use patterns, especially with fentanyl. It may help people who use opioids outside of medical settings to more accurately report their use.
Baltimore, MarylandAges 18–99 - NCT06676059Recruiting
Substance use monitoring study with a smartphone app
This study uses a smartphone app and daily surveys to track alcohol or drug use. It aims to create a database for future research on addiction patterns and recovery.
Baltimore, MarylandAges 18–120 - NCT03394066Recruiting
Magnetic brain stimulation safety and brain imaging study
This study tests how a non-invasive magnetic stimulation technique affects the brain in healthy volunteers. It involves MRI scans and aims to understand brain function without surgery.
Baltimore, MarylandAges 18–60 - NCT05630781Recruiting
Orexin's role in the neurobiology of addiction
This study looks at how a brain chemical called orexin affects addiction. Researchers will give a medication that blocks orexin to see if it helps reduce cravings or use. It might help people who smoke or vape regularly.
Baltimore, MarylandAges 18–60 - NCT05538910Recruiting
Study brain links between depression and substance use
This study uses brain imaging and questionnaires to understand how substance use and depression are connected in the brain. It may help researchers identify biological patterns that could guide better treatments in the future.
Baltimore, MarylandAges 18–60 - NCT05707806Recruiting
Brain and decision tasks to study learning
This study tests how people learn from choices and make decisions using computer tasks. Some participants also complete brain scans (MRI) to see how the brain activity matches behavior.
Baltimore, MarylandAges 18–45 - NCT05722561RecruitingPhase 2
E-cigarettes to reduce smoking in opioid use disorder
This Phase 2 study tests whether e-cigarettes can help people who use opioids (and also smoke cigarettes) cut down on combustible cigarette smoking. It looks at whether switching to e-cigarettes for “harm reduction” is safe and helps you smoke fewer cigarettes without requiring you to quit completely.
New York, New YorkAges 21–75 - NCT05807139RecruitingPhase 1
Spironolactone for alcohol use disorder
This Phase 1 study tests whether spironolactone (a medicine that affects salt and hormone balance) is safe and potentially helpful in people with alcohol use disorder. You may be eligible if you are currently drinking heavily, have low alcohol withdrawal symptoms, and meet several lab and medication safety rules.
Baltimore, MarylandAges 21–99
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Common questions
- Are there clinical trials for drug abuse?
- Yes. Clin2 currently lists 37 recruiting drug abuse studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a drug abuse trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a drug abuse trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.