Clinical trials
Drug Use clinical trials
Below are recruiting drug use clinical trials, each written for real people, not researchers. We’re tracking 143 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02299921Recruiting
Alcohol and drug effects on immunity in ICU breathing patients
This study looks at how alcohol and other drugs can affect the body’s immune system in people who are very sick in the ICU due to breathing problems. It may help doctors better understand immune changes during critical illness and respiratory failure.
Aurora, ColoradoAges 18–90 - NCT06395129Recruiting
Better syringes for people who inject drugs
This study provides safer, low-dead-space syringes to people who inject drugs to help reduce the spread of infections like HIV and hepatitis C. It is designed for people in low- and middle-income countries who use needle exchange programs.
YerevanAges 18 years+ - NCT06651333Recruiting
Brain scans during opioid addiction treatment
This study uses brain scans to understand how methadone or buprenorphine treatment affects the brain, with the goal of helping people stay in treatment and avoid relapse. You would need to be recently started on one of these medications and be able to undergo MRI scans.
Hartford, ConnecticutAges 18–50 - NCT06307977Recruiting
Couples counseling to reduce drug use and HIV risk
This study tests a couple-focused counseling approach to help male couples reduce drug use and lower the risk of HIV. You and your partner would join sessions together to talk about safer choices and support each other.
Detroit, MichiganAges 18–55 - NCT04811014RecruitingPhase 4
Helping young adults stop opioids after an emergency visit
This study offers an engagement program for young people who tested positive for opioids and meet criteria for opioid dependence. The goal is to help participants stop opioid use safely and learn whether this approach works well in the real-world emergency setting.
Houston, TexasAges 13–17 - NCT07387796Recruiting
Brain and behavior changes with tirzepatide stop and restart
This study looks at how your brain and behavior change when you stop and then restart the weight loss drug tirzepatide. It will help researchers understand what happens during treatment breaks.
Dallas, TexasAges 18–70 - NCT07541131Enrolling by invitation
Reducing HIV stigma to improve treatment access for drug users
This study tests whether reducing stigma and discrimination against people who use drugs can help more people access HIV treatment and prevention. You would participate in peer-led group sessions and surveys over 18 months to help researchers understand how stigma affects treatment access in Bishkek.
BishkekAges 18 years+ - NCT05342493Recruiting
Survey study of long-term Ajovy injections
This is a study that collects information about how people use Ajovy (a medication for migraine) over time by injection. It mainly looks at safety and real-world use, and it may help researchers understand long-term treatment needs.
OsakaAges 18 years+ - NCT05032053Recruiting
Blood thinner use after stroke in people with small bleeds
This trial studies whether using blood-thinning medicine is safe and appropriate for people after an ischemic stroke who also have small signs of bleeding in the brain. It aims to balance stroke prevention with the risk of bigger bleeding.
Ankang, ShaanxiAges 40 years+ - NCT06757257Recruiting
Long-term use survey of fostamatinib for ITP
This study follows people with chronic immune thrombocytopenia (ITP) who are starting fostamatinib for the first time. It aims to gather information on how well the medicine works and how safe it is when used over a longer period.
Tokyo and Japanese Other CitiesAges Any age - NCT06758271Recruiting
Long-term study of avacopan for vasculitis
This study looks at the long-term safety and effectiveness of avacopan in people with certain types of vasculitis (GPA or MPA). It may help doctors understand how well the medicine works over time.
Multiple LocationsAges Any age - NCT07758907Enrolling by invitation
Testing a device that reads fingerprints for drug screening
This trial tests a new drug screening system that reads fingerprints to detect drugs in the body. It will check if certain medications interfere with the device's accuracy, which may lead to faster and easier drug testing in the future.
Marlton, New JerseyAges 18–55 - NCT07077473Recruiting
Comparing FMF treatments used in daily care
This study looks at how well and safely different real-world treatments work for people with Familial Mediterranean Fever (FMF). It aims to find which medicines help best for this inherited inflammatory disorder.
Wuhan, HubeiAges Any age - NCT05599438Recruiting
Fitness and drug use study in recreational athletes
This study follows recreational athletes to understand how past and current anabolic-androgenic steroid (AAS) use relates to fitness changes over time. If you have used these substances in the past (and stopped more than 3 months ago), or you have never used them, you may be able to join.
CopenhagenAges 18 years+ - NCT07751978Recruiting
HIV care support for women who inject drugs
This study tests a program to help women living with HIV who also inject drugs stay engaged in their HIV care. It aims to reduce stigma and improve health outcomes.
Kyiv, Kyiv OblastAges 18 years+ - NCT07741825Recruiting
Mindfulness training to prevent relapse for peer support workers
This study tests a mindfulness-based program to help people who work as peer support specialists in substance use recovery reduce their risk of relapse. It may help you manage cravings and stay healthy in your role.
Austin, TexasAges 18–100 - NCT07625917Recruiting
Testing an online HIV prevention program for people who inject drugs
This study tests whether an internet-based HIV prevention program works for people who use injection drugs. Researchers want to see if online tools can help reduce HIV risk and improve health outcomes.
The Bronx, New YorkAges 18 years+ - NCT06405490RecruitingPhase 2
Chemo plus immunotherapy for first-line advanced pancreatic cancer
This trial tests a combination of chemotherapy (NALIRI-XELOX) plus a newer immunotherapy drug (AK104) as a first treatment for people with advanced pancreatic cancer that hasn't been treated yet. The goal is to see if this combination works better than standard treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05089448RecruitingPhase 4
Morning vs bedtime blood pressure medicine dosing study
This trial tests whether taking your blood pressure medicine in the morning or at bedtime controls blood pressure better over a full day and night. It may help certain people find a dosing time that improves nighttime blood pressure.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT05655702Recruiting
Drug use and infections study for tuberculosis control in Vietnam
This study looks at how injecting drug use is linked with infections, including tuberculosis, and aims to improve TB control. You may be asked to share information and provide tests related to recent drug use and injection sites.
HaiphongAges 18 years+ - NCT06436092Recruiting
Stent treatment for left main coronary artery disease
This trial studies a new way to treat blockages in the left main coronary artery using a drug-coated stent. It aims to find out if a careful approach with a single stent and temporary side-branch support works well for people with heart disease.
Ichinomiya, Aichi-kenAges 18 years+ - NCT07180368Recruiting
Managing multiple medications in older adults
This study looks at how to better manage multiple medications in older adults with long-term health conditions. It aims to improve safety and reduce drug-related problems.
Xi'an, ShaanxiAges 65 years+ - NCT06322433Recruiting
Follow-up study for severe nearsightedness
This study follows people with high myopia over time to monitor their eye health. It aims to better understand how very nearsighted eyes change.
MilanAges 18 years+ - NCT07053891Recruiting
Safety survey of LUPKYNIS for lupus nephritis
This study is a safety survey for people who are just starting to take LUPKYNIS for lupus nephritis, a type of kidney inflammation caused by lupus. It aims to collect information on how well the drug works and any side effects in real-world use.
Osaka, OsakaAges 15 years+
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Common questions
- Are there clinical trials for drug use?
- Yes. Clin2 currently lists 143 recruiting drug use studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a drug use trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a drug use trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.