Clinical trials
Dry Eye clinical trials
Below are recruiting dry eye clinical trials, each written for real people, not researchers. We’re tracking 106 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07593885Recruiting
Artelac Complete versus VISMED MULTI for severe dry eye
This study compares two preservative-free eye drops designed to treat moderate to severe dry eye disease. It evaluates which product works better and is safer for people whose dry eyes are caused by conditions like Sjögren's disease, autoimmune blistering disorders, or damaged tear glands.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT07618364Recruiting
Rinsing to reduce eye inflammation in dry eye disease
This study tests whether rinsing the eye surface helps reduce inflammation and symptoms in people with dry eyes. Participants must have a specific inflammatory marker (MMP-9) in both eyes.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07650708RecruitingPhase 4
Eye Dryness After LASIK Surgery With a New Dry Eye Treatment
This study tests whether a new eye lubricant called Miebo, given before LASIK vision correction surgery, reduces dry eye symptoms afterward. If you have mild-to-moderate dry eyes and need LASIK, this trial may help you stay more comfortable during your recovery.
Bozeman, MontanaAges 18 years+ - NCT07553455Enrolling by invitationPhase 4
Vevye plus Flarex eye drops for moderate to severe dry eye
This study tests a combination of two eye drop medications (Vevye and Flarex) to see if they work better together for treating moderate to severe dry eye. If you have persistent dry eye that hasn't improved with other treatments, this trial might help you and advance treatment options.
Azusa, CaliforniaAges 18 years+ - NCT06860659Enrolling by invitationPhase 4
Hyaluronate eye drops for moderate to severe dry eye
This trial tests whether 0.28% sodium hyaluronate eye drops can help people with moderate to severe dry eye feel better. It's for patients who have significant dry eye symptoms and signs on an eye exam.
Bangkok, BangkokAges 18 years+ - NCT04673643RecruitingPhase 2
Nerve stimulation for dry eye symptoms
This Phase 2 study tests a device that delivers gentle stimulation to a nerve near the ear to help improve dry eye disease. It may help reduce dryness and discomfort, if you meet the study’s health and safety requirements.
BeijingAges 18–65 - NCT06017362RecruitingPhase 4
Insulin drops for dry eye in glaucoma patients
This study tests whether insulin eye drops can safely help dry eye in people who also use eye drops for glaucoma. It may offer a new option if you have both conditions and your eye pressure is stable.
Madrid, MadridAges 18 years+ - NCT06360133RecruitingPhase 3
New eye drop for dry eye disease
This study tests a new eye drop (5% VVN001) to treat dry eye disease that hasn't improved enough with artificial tears. It may help people with moderate-to-severe dry eye and low tear production.
Shanghai, Shanghai MunicipalityAges 30–80 - NCT06543303RecruitingPhase 2
Testing BTV100 for moderate to severe dry eye
This trial tests BTV100, an investigational eye drop, for people with ongoing moderate to severe dry eye disease. It aims to see if the treatment can improve dryness and discomfort.
Doncaster East, VictoriaAges 18 years+ - NCT06615453Recruiting
Tixel treatment for dry eye disease and periorbital wrinkles
This study tests a device called Tixel that may help reduce wrinkles around the eyes and improve dry eye symptoms. If you have mild to moderate under-eye wrinkles and dry eyes that bother you a lot, this treatment might be an option.
BirminghamAges 18 years+ - NCT06771427Recruiting
Exosomes for Sjogren's and Dry Eye
This study looks at tiny particles called exosomes in tears to find new ways to diagnose or treat Sjogren's syndrome and dry eye disease. It may help people with these conditions by learning more about what causes them.
Taipei, TaiwanAges 20–75 - NCT06879782RecruitingPhase 3
Eye drops for dry eye disease: a phase 3 study
This study tests an eye drop called lifitegrast for people with dry eye disease. It looks at whether the drops can improve eye comfort, reduce dryness, and help eye surface health. You may be able to join if you have had dry eye symptoms and used artificial tears in the past month.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06939959RecruitingPhase 4
Insulin eye drops for dry eye disease
This trial tests whether a new type of eye drop made with insulin can help restore the eye's surface and reduce dry eye symptoms. It may be an option for people with moderate to severe dry eye who haven't improved with other treatments.
Peshawar, Khyber PukhtunkhwaAges 18 years+ - NCT07245017RecruitingEarly Phase 1
Testing JN002 drops for dry eye disease
This trial tests whether a new eye drop, JN002, can help people with dry eye disease. It checks if the drops improve symptoms and eye health over time.
ShanghaiAges 18 years+ - NCT07298811RecruitingPhase 1/Phase 2
Healthy eye bacteria for dry eye treatment
This study tests whether putting healthy bacteria from a family member's eye surface onto your eyes can help treat moderate to severe dry eye. You would receive standard dry eye drops plus the experimental transplant.
Nanchang, JiangxiAges 18–70 - NCT07363824Recruiting
Tear iron and dry eye severity study
This study looks at how iron levels in tears relate to the severity of dry eye disease. It aims to find a simple way to measure dry eye severity, which could help doctors better understand and treat the condition.
ShanghaiAges 18–70 - NCT07412860Recruiting
Eye drop test for moderate to severe dry eye
This trial tests a new eye drop (FBV_01) compared to a standard hyaluronic acid eye drop for people with moderate to severe dry eye. The goal is to see if the new drop provides better relief.
Cagliari, CAAges 18 years+ - NCT07548632RecruitingPhase 2/Phase 3
Testing a new eye drop medicine for dry eye disease
This study tests whether licaminlimab, a new type of eye drop medicine, helps relieve dry eye disease. You'll use the study medicine for several weeks while doctors track how your symptoms and eye health improve.
Aliso Viejo, CaliforniaAges 18 years+ - NCT07606625RecruitingPhase 4
Nasal spray for dry eye disease and tear film stability
This study tests whether a nasal spray can improve dry eye symptoms and tear production in people with mild to moderate meibomian gland dysfunction (a common cause of dry eye). You'll use the spray daily while the research team monitors your eye health and comfort over several weeks.
Berkeley, CaliforniaAges 18 years+ - NCT07623382RecruitingEarly Phase 1
Stem Cell Treatment for Dry Eye Disease
This early-stage trial tests whether special cells derived from umbilical cord tissue can help treat dry eye disease. The treatment uses tiny particles called extracellular vesicles that may reduce eye dryness and improve comfort.
Xiamen, ChinaAges 18 years+ - NCT07656688RecruitingPhase 2
Finding the best dose for a dry eye treatment
This trial tests different doses of a new eye drop (HUC1-394) to see which dose works best for people with moderate to severe dry eye disease. You may qualify if your dry eye symptoms have lasted at least 3 months and you have low tear production along with other signs of dry eye.
SeoulAges 19 years+ - NCT07503886RecruitingPhase 2
Study of an eye drop for dry eye disease
This trial tests a new eye drop called DFL24498 to see if it helps people with dry eye disease. You may qualify if your dry eye is moderate to severe and other treatments haven't worked well for you.
Chandler, ArizonaAges 18 years+ - NCT07171710Enrolling by invitation
Cyclosporine eye drops and tear duct plugs for dry eye in Sjögren's
This trial tests if using special eye drops (cyclosporine) along with tiny plugs placed in the tear ducts can improve dry eye symptoms in people with Sjögren's syndrome. The goal is to see if this combination works better than the drops alone.
Tianjin, Tianjin MunicipalityAges Any age - NCT07732010RecruitingPhase 4
Tryptophan for dry eye disease
This trial tests whether a dietary supplement called TRYPTYR can improve dry eye symptoms. You may qualify if you have moderate dry eye with certain signs, like short tear breakup time and staining on your eye surface.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for dry eye?
- Yes. Clin2 currently lists 106 recruiting dry eye studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dry eye trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dry eye trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.