Clinical trials
Dry Eye clinical trials
Below are recruiting dry eye clinical trials, each written for real people, not researchers. We’re tracking 98 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05865379Recruiting
Tested eye drops for dry eye relief and safety
This trial studies whether BUFY01 eye drops work better than SVS20 for treating dry eye disease. You may be able to join if you have dry eye symptoms for at least 3 months and meet eye exam score and tear-test requirements.
LeuvenAges 18 years+ - NCT05865457Recruiting
Testing two eye treatments for dry eye symptoms
This trial compares two different dry-eye eye drops to see which works better and is safe. You may be able to join if you’ve had dry eye for at least 3 months and meet specific eye-test results.
GrazAges 18 years+ - NCT06017362RecruitingPhase 4
Insulin drops for dry eye in glaucoma patients
This study tests whether insulin eye drops can safely help dry eye in people who also use eye drops for glaucoma. It may offer a new option if you have both conditions and your eye pressure is stable.
Madrid, MadridAges 18 years+ - NCT07656688RecruitingPhase 2
Finding the best dose for a dry eye treatment
This trial tests different doses of a new eye drop (HUC1-394) to see which dose works best for people with moderate to severe dry eye disease. You may qualify if your dry eye symptoms have lasted at least 3 months and you have low tear production along with other signs of dry eye.
SeoulAges 19 years+ - NCT07623382RecruitingEarly Phase 1
Stem Cell Treatment for Dry Eye Disease
This early-stage trial tests whether special cells derived from umbilical cord tissue can help treat dry eye disease. The treatment uses tiny particles called extracellular vesicles that may reduce eye dryness and improve comfort.
Xiamen, ChinaAges 18 years+ - NCT07606625RecruitingPhase 4
Nasal spray for dry eye disease and tear film stability
This study tests whether a nasal spray can improve dry eye symptoms and tear production in people with mild to moderate meibomian gland dysfunction (a common cause of dry eye). You'll use the spray daily while the research team monitors your eye health and comfort over several weeks.
Berkeley, CaliforniaAges 18 years+ - NCT07548632RecruitingPhase 2/Phase 3
Testing a new eye drop medicine for dry eye disease
This study tests whether licaminlimab, a new type of eye drop medicine, helps relieve dry eye disease. You'll use the study medicine for several weeks while doctors track how your symptoms and eye health improve.
Aliso Viejo, CaliforniaAges 18 years+ - NCT07503886RecruitingPhase 2
Study of an eye drop for dry eye disease
This trial tests a new eye drop called DFL24498 to see if it helps people with dry eye disease. You may qualify if your dry eye is moderate to severe and other treatments haven't worked well for you.
Chandler, ArizonaAges 18 years+ - NCT06771427Recruiting
Exosomes for Sjogren's and Dry Eye
This study looks at tiny particles called exosomes in tears to find new ways to diagnose or treat Sjogren's syndrome and dry eye disease. It may help people with these conditions by learning more about what causes them.
Taipei, TaiwanAges 20–75 - NCT07412860Recruiting
Eye drop test for moderate to severe dry eye
This trial tests a new eye drop (FBV_01) compared to a standard hyaluronic acid eye drop for people with moderate to severe dry eye. The goal is to see if the new drop provides better relief.
Cagliari, CAAges 18 years+ - NCT07363824Recruiting
Tear iron and dry eye severity study
This study looks at how iron levels in tears relate to the severity of dry eye disease. It aims to find a simple way to measure dry eye severity, which could help doctors better understand and treat the condition.
ShanghaiAges 18–70 - NCT06879782RecruitingPhase 3
Eye drops for dry eye disease: a phase 3 study
This study tests an eye drop called lifitegrast for people with dry eye disease. It looks at whether the drops can improve eye comfort, reduce dryness, and help eye surface health. You may be able to join if you have had dry eye symptoms and used artificial tears in the past month.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07245017RecruitingEarly Phase 1
Testing JN002 drops for dry eye disease
This trial tests whether a new eye drop, JN002, can help people with dry eye disease. It checks if the drops improve symptoms and eye health over time.
ShanghaiAges 18 years+ - NCT07171710Enrolling by invitation
Cyclosporine eye drops and tear duct plugs for dry eye in Sjögren's
This trial tests if using special eye drops (cyclosporine) along with tiny plugs placed in the tear ducts can improve dry eye symptoms in people with Sjögren's syndrome. The goal is to see if this combination works better than the drops alone.
Tianjin, Tianjin MunicipalityAges Any age - NCT06615453Recruiting
Tixel treatment for dry eye disease and periorbital wrinkles
This study tests a device called Tixel that may help reduce wrinkles around the eyes and improve dry eye symptoms. If you have mild to moderate under-eye wrinkles and dry eyes that bother you a lot, this treatment might be an option.
BirminghamAges 18 years+ - NCT06360133RecruitingPhase 3
New eye drop for dry eye disease
This study tests a new eye drop (5% VVN001) to treat dry eye disease that hasn't improved enough with artificial tears. It may help people with moderate-to-severe dry eye and low tear production.
Shanghai, Shanghai MunicipalityAges 30–80 - NCT07842536Recruiting
Goji berry extract for dry eye disease
This trial tests whether a supplement made from goji berries can help people with dry eye disease. Dry eyes happen when your eyes do not make enough tears or the tears evaporate too quickly, which can cause discomfort and blurry vision. The study aims to see if this natural supplement improves symptoms and signs of dry eye.
Hong Kong, Hong KongAges 18–60 - NCT07796178RecruitingPhase 4
Dry eye relief and comfort after cataract surgery
This study tests a treatment called Lacrifill to see if it helps reduce dry eye symptoms after cataract surgery. You would receive the treatment after your surgery to see if it improves comfort and eye health.
Pittsburg, KansasAges 18–80 - NCT07732010RecruitingPhase 4
Tryptophan for dry eye disease
This trial tests whether a dietary supplement called TRYPTYR can improve dry eye symptoms. You may qualify if you have moderate dry eye with certain signs, like short tear breakup time and staining on your eye surface.
New York, New YorkAges 18 years+ - NCT07657858Recruiting
Does Dry Eye Treatment Affect Astigmatism Measurements Before Cataract Surgery?
This study checks whether treating dry eyes before cataract surgery can change the way your eye's shape (astigmatism) is measured. It may help make your surgery more accurate.
Shanghai, Shanghai MunicipalityAges Any age - NCT07268599Enrolling by invitation
Acoltremon for moderate-to-severe dry eye relief
This study tests a new eye drop called Acoltremon to see if it can relieve symptoms of moderate-to-severe dry eye disease. It may be a good option if you have had dry eye for at least 6 months and use artificial tears.
Encino, CaliforniaAges 18–60 - NCT06298890Recruiting
Dry eye pattern after cataract surgery
This study looks at how dry eye symptoms change after cataract surgery. It is for older adults (50–90) having simple cataract surgery for the first time, without other eye problems or certain health conditions.
KaunasAges 50–90 - NCT07396441RecruitingPhase 4
Kelulut honey therapy for juvenile glaucoma
This trial tests if adding Kelulut honey to standard treatment can help protect the optic nerve in young people with juvenile open-angle glaucoma. It looks at eye pressure, nerve thickness, and dry eye symptoms.
Kota Bharu, KelantanAges 15–40 - NCT06766357RecruitingPhase 3
Cyclosporin gel for moderate to severe dry eye
This study tests a gel form of cyclosporine for people with moderate to severe dry eye that hasn't improved with other treatments. The gel is applied to the eye to help reduce inflammation and increase tear production.
Xiamen, FujianAges 18 years+
Hear when a new Dry Eye trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for dry eye?
- Yes. Clin2 currently lists 98 recruiting dry eye studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dry eye trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dry eye trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.