Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,360 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03155854Recruiting
Surgery to prevent scarring in trigger finger
This study looks at whether doing a limited surgery in advance can improve outcomes and reduce scarring for people with trigger finger who also have a specific palm cord condition. It may help you heal better if you’ve already tried non-surgical treatment or chose surgery.
Rochester, MinnesotaAges 18 years+ - NCT03101722Enrolling by invitation
Huperzine A for hearing loss, tinnitus, and mild memory issues
This trial tests whether huperzine A can improve hearing-related symptoms along with tinnitus (ringing) and mild cognitive (memory/thinking) problems. If you have mild-to-moderate hearing loss plus bothersome constant tinnitus and some cognitive decline, this study may help researchers see if the treatment makes a difference.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT03158090Recruiting
Study of treatment patterns for acromegaly over time
This study follows people with acromegaly to better understand how treatments are used in real life and how well they work over time. It may help improve future treatment choices by comparing outcomes across different care patterns.
Guangzhou, GuangdongAges 18–75 - NCT03286569Recruiting
Braces study for children to move the lower jaw forward
This study looks at whether a removable mouth “expansion appliance” can help the lower jaw grow forward in children whose bite is too far back. It may help improve the way the upper and lower teeth and jaws fit together.
Edmonton, AlbertaAges 9–11 - NCT07592494Recruiting
Arm Exercise Training for Heart Failure With Device
This study compares different types of arm exercises for people with heart failure who have a pacemaker or defibrillator implanted. The goal is to see which exercise approach best improves how well your arms function and help you stay active.
ÇorumAges 18 years+ - NCT07442045Recruiting
Comparing combined vs single drug for ulcerative colitis
Researchers want to see if taking two medications together (upadacitinib and vedolizumab) works better than taking just upadacitinib alone for people with moderate to severe ulcerative colitis. This is a real-world study, meaning it looks at patients being treated in normal medical practice.
Foshan, GuangdongAges 18 years+ - NCT07646847Recruiting
A support program for people with cancer on immunotherapy
This study tests a program that helps people with cancer manage side effects and find resources for needs like food, transportation, or housing. It is for patients who are starting or recently started immunotherapy for certain cancers.
Basking Ridge, New JerseyAges 18 years+ - NCT07525960RecruitingPhase 1
Testing NDI-5001 for X-linked Nephrogenic Diabetes Insipidus
This study tests a new drug called NDI-5001 in adult men with a specific genetic form of nephrogenic diabetes insipidus (a condition where the kidneys cannot concentrate urine properly). The trial checks whether the drug is safe, how your body handles it, and whether it might help reduce excessive urination and thirst.
Jacksonville, FloridaAges 18–55 - NCT07607366Recruiting
Negative Pressure Bandaging After Breast Removal Surgery
This trial tests a special bandage that uses gentle suction to help wounds heal better after breast cancer surgery. Researchers want to see if this type of bandaging reduces complications like fluid buildup and improves healing.
FalunAges 18 years+ - NCT07628634RecruitingEarly Phase 1
Testing a Low-Methionine Diet in Solid Tumor Patients
This early-stage study explores whether eating a diet low in methionine (a natural amino acid found in protein) might help people with advanced solid tumors. Researchers will track how this dietary change affects blood levels and may improve treatment outcomes alongside standard cancer care.
Orange, CaliforniaAges 18 years+ - NCT07734623Recruiting
Ultrasound treatment for severe opioid or amphetamine use disorder
This trial tests a low-intensity focused ultrasound treatment for people with severe opioid or amphetamine use disorder. The ultrasound targets a part of the brain linked to addiction, and the goal is to see if it is safe and helpful.
TaipeiAges 20–50 - NCT07739238Recruiting
Breathing Exercises and Heart Health Study
This study tests whether different breathing exercises can improve lung function and heart rate variability in healthy, inactive young adults. It may help you understand how simple breathing techniques can affect your breathing and heart health.
Balıkesir, In the USA Or Canada, Please Select...Ages 18–30 - NCT07739784Recruiting
Personality and side effects of glaucoma eye drops
This study looks at whether your personality affects how you experience side effects from glaucoma eye drops. The results may help doctors choose the best treatment for you and provide more personalized care.
Montreal, QuebecAges 18 years+ - NCT07739082Recruiting
Virtual reality for teens with hunched back
This study tests if virtual reality exercises can improve posture in teens with a hunched back (thoracic hyperkyphosis). It may help by making therapy more engaging and effective.
CairoAges 13–18 - NCT02844738RecruitingPhase 2
Cell therapy for shoulder osteoarthritis pain and inflammation
This trial tests a treatment using your own (autologous) regenerative cells to reduce pain and inflammation from shoulder osteoarthritis. It may help people with long-lasting shoulder pain, but you must meet several health and medication timing requirements.
Grove City, PennsylvaniaAges 18–90 - NCT02844764RecruitingPhase 2
Cell therapy test for hip osteoarthritis pain and swelling
This trial tests an “autologous” regenerative cell treatment, meaning cells taken from you, to reduce hip osteoarthritis pain and inflammation. It checks safety first and looks for improvements in how you feel and move.
Grove City, PennsylvaniaAges 18–90 - NCT02844751RecruitingPhase 2
Regenerative knee cell therapy for arthritis pain and swelling
This Phase 2 study tests a patient’s own (autologous) regenerative cell treatment to reduce knee pain and inflammation from osteoarthritis. It mainly looks at whether the treatment is safe and whether it can improve symptoms over time.
Grove City, PennsylvaniaAges 18–90 - NCT02784210RecruitingPhase 2
Steroid treatment to reduce inflammation in active MS lesions
This Phase 2 study tests whether corticosteroid medicine can reduce inflammation at the edge of active multiple sclerosis (MS) plaques seen on MRI. It may help calm “hot” areas in the brain where MS activity is happening.
Bethesda, MarylandAges 18–120 - NCT07740265Recruiting
Scanning methods for jaw dentures on implants
This study compares different scanning techniques for making dentures that attach to dental implants in the lower jaw. It aims to find the most accurate method to fit dentures comfortably.
Tanta, Gharbia GovernorateAges 40–60 - NCT02947503RecruitingPhase 3
Metformin for gestational diabetes in pregnancy outcomes
This study tests whether taking metformin during pregnancy improves outcomes for people with gestational diabetes. It may help with pregnancy health and baby outcomes compared with the study’s other diabetes care plan.
GroningenAges 18–45 - NCT02823665RecruitingEarly Phase 1
Compare how bariatric surgery affects blood sugar changes
This early trial studies how blood sugar moves in people after certain weight-loss surgery compared with people without surgery. It may help researchers understand why blood sugar can drop too low and how treatments like atropine affect that process.
San Antonio, TexasAges 18–65 - NCT02791152Recruiting
Exercise and blood pressure monitoring in healthy adults
This study looks at how physical activity and regular blood pressure checks relate to heart health signals on imaging. It’s meant for people without major heart, stroke, diabetes, or serious chronic illnesses to understand early cardiovascular risk.
Singapore, SingaporeAges 21–69 - NCT02836158RecruitingPhase 2/Phase 3
Test drug plus spinal chemotherapy for older PCNSL
This trial studies whether adding R-IDARAM and medication delivered into the spinal fluid can improve treatment for primary central nervous system lymphoma (PCNSL) in newly diagnosed older adults. It may help by targeting lymphoma cells in the brain, covering membranes, and spinal fluid.
Beijing, Beijing MunicipalityAges 60–75 - NCT02923011RecruitingPhase 3
MR-guided ultrasound vs radiofrequency heat for osteoid osteoma pain
This trial compares two non-surgical treatments that heat a small bone tumor to stop pain: MR-guided focused ultrasound and radiofrequency heat. It aims to find which option works better and has fewer problems for people whose osteoid osteoma pain is not well controlled.
Palo Alto, CaliforniaAges 8 years+
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,360 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.