Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,360 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02630121RecruitingPhase 4
Nasal spray treatment to reduce mild sleep apnea congestion
This study tests whether using oxymetazoline with fluticasone nasal spray can improve mild obstructive sleep apnea by lowering nasal congestion. If your nose stays blocked most days despite current spray use, this may help your breathing during sleep.
Tampa, FloridaAges 18–65 - NCT02559804Recruiting
Study of nerve tumors in children affecting the spine canal
This study follows children and teens with certain nerve-cell tumors (like neuroblastoma) that involve the spinal canal. It collects information on how these tumors behave and how treatments and outcomes may differ, aiming to improve care over the long term.
GenovaAges Up to 18 years - NCT02610855Enrolling by invitation
Study of activity and muscle function in children with scoliosis
This study looks at how children’s activity levels and muscle performance change in different scoliosis treatments (surgery, bracing, or healthy peers). It uses motion sensors and an ultrasound-based test to better understand what treatments may do to the body’s muscles.
Rochester, MinnesotaAges 9–16 - NCT02323945Recruiting
Low-oxygen breathing to improve leg movement after spinal injury
This study tests whether breathing brief, mild low-oxygen air (under supervision) can improve leg mobility in people with a certain type of spinal cord injury. It may help with regaining movement, especially if you can already move your legs voluntarily but still have mobility limits.
Cambridge, MassachusettsAges 18–75 - NCT02257723Recruiting
Testing combined Korean herbal and therapy for hospitalized spine or joint pain
This trial studies whether a combined complementary treatment approach helps people who are hospitalized for spine or joint problems. It may help reduce the types of pain that come from those areas.
Seoul, Gangnam-GuAges Any age - NCT02195050Recruiting
Study links between abnormal blood fats and health risks
This study looks at why triglycerides and cholesterol can be abnormal and how that may affect organs like nerves, liver, and metabolism. You may be included if you already take a statin, have certain triglyceride levels, diabetes, kidney disease, or specific lab patterns suggesting inherited fat disorders.
ManchesterAges 18 years+ - NCT07742488Recruiting
Statins and hormone therapy for cholesterol in menopause
This study looks at whether taking statins (cholesterol-lowering medicine) along with hormone replacement therapy (HRT) affects blood clotting in women going through menopause who have high cholesterol. It may help doctors understand how these medicines work together.
Pisa, ItalyAges 45–55 - NCT07538050Recruiting
Testing a new, affordable HPV screening method
This study tests ScreenFire, a new low-cost test for HPV (a virus linked to cervical cancer) that you can do yourself at home. Researchers want to see if it works as well as standard tests and costs less.
San Salvador, OrienteAges 30–59 - NCT07518953Recruiting
Can Music Help With Pain During a Nail Biopsy?
This study tests whether listening to music during a nail biopsy—a small procedure to remove a sample of nail tissue—can reduce pain and anxiety. You would listen to music during the procedure and answer a few questions about how you felt.
New York, New YorkAges 18 years+ - NCT07602270Recruiting
How a Ketogenic Diet Affects Alcohol in Your Body
This study tests whether eating a ketogenic diet (very low carb, high fat) changes how your body processes alcohol. Researchers will have you follow a special diet and then measure your body's response to controlled amounts of alcohol in a lab setting.
Philadelphia, PennsylvaniaAges 21–50 - NCT07667556Recruiting
Frozen shoulder treatment: gentle movement, pain education, and core exercises
This study tests whether a combination of gentle joint movement techniques, pain education, and core-strengthening exercises can help people with frozen shoulder move better and feel less pain. It may be a good fit if you have been diagnosed with frozen shoulder and are looking for a drug-free treatment option.
IstanbulAges 18–65 - NCT07744022Recruiting
Exercise comparison for children with obesity
This study compares two types of exercise programs — progressive neuromuscular stabilization exercises versus aerobic exercises — to see which one better improves body composition and balance in children with obesity. It aims to find a fun, effective way to help kids move better and feel healthier.
IstanbulAges 12–18 - NCT07745062RecruitingPhase 4
Comparing two eye drops for mild to moderate dry eye
This study tests two types of preservative-free eye drops to see which is more effective for people with mild to moderate dry eye disease. You will use one of the drops as directed, and the study will monitor your symptoms and eye health over time.
La Jolla, CaliforniaAges 18 years+ - NCT07744373Recruiting
Breast milk study for infant food tolerance
This study looks at cells and molecules in breast milk that may affect how babies develop tolerance to foods. If you are a mother exclusively breastfeeding and your baby is under 9 months old, you may be able to join.
IstanbulAges birth–9 months - NCT01989013Enrolling by invitation
CranioSacral therapy for people with Parkinson’s disease
This study looks at whether a hands-on therapy called CranioSacral Integrated Therapy can improve symptoms in people with Parkinson’s disease. If you have Parkinson’s, the goal is to see whether this treatment changes how you feel or function.
Ann Arbor, MichiganAges 18 years+ - NCT01402661Enrolling by invitation
Rheumatoid arthritis drug safety and effectiveness registry
This registry collects real-world information about people with rheumatoid arthritis (RA) to help doctors understand how RA medicines work and their safety. You may be able to join if you’re newly diagnosed or starting certain RA treatments and you’re willing to share consent and basic personal details.
Waltham, MassachusettsAges 18 years+ - NCT01631617RecruitingPhase 2
Atopic dermatitis treatments and how they affect skin
This Phase 2 study tests different treatments for atopic dermatitis (eczema) by looking at changes in skin health. It may help people find safer, more effective ways to control moderate to severe eczema and related skin infections.
Bethesda, MarylandAges 2–50 - NCT07551323Recruiting
Myofascial Release vs. Pilates for Chronic Low Back Pain
This study compares two hands-on treatment approaches—myofascial release (deep tissue massage) and Pilates exercises—to see which works better for chronic low back pain that isn't caused by nerve damage. If you have persistent lower-back pain, this trial might help you find relief through one of these therapies.
Istanbul, IstanbulAges 18–45 - NCT01604395Recruiting
Long-term growth hormone check for children with short stature
This study follows children who are short for their age and checks how safe and effective growth hormone is over the long term. It may help families understand expected benefits and side effects for their specific growth-related condition.
SeoulAges 2 years+ - NCT01719055Recruiting
Long-term follow-up for Boston Scientific pain nerve stimulation
This study looks at how well a Boston Scientific nerve stimulation device works over the long term for pain in everyday care. You may be able to join if you’re already being set up to use one of these approved systems and can reliably report your pain outcomes.
Phoenix, ArizonaAges 18 years+ - NCT01629017Recruiting
Long-term follow-up after a stem cell transplant
This study looks at the long-term health effects of hematopoietic (blood-forming) stem cell transplants. It may help doctors better understand and manage late side effects for children and teens after transplant.
Stanford, CaliforniaAges Up to 18 years - NCT01653223Recruiting
Simvastatin to protect the heart during heart surgery
This trial looks at whether simvastatin (a cholesterol medicine) can help protect the heart during cardiac surgery. You might be invited if you’re having surgery for certain, non-complex heart conditions, but not if you have some specific related health problems.
Guangzhou, GuangdongAges 18 years+ - NCT01477957Recruiting
Bariatric surgery and changes in insulin and body energy use
This study tests whether weight-loss surgery improves how your body uses insulin and energy. It compares insulin sensitivity and related measurements before and after surgery to understand who benefits.
Düsseldorf, North Rhine-WestphaliaAges 20–70 - NCT02038517Recruiting
Liver transplant waitlist study for people without diabetes
This study is for people with end-stage cirrhosis who are on the liver transplant waitlist at this hospital. It aims to understand how getting a liver transplant may affect people with and without diabetes-related issues.
Milan, MIAges 18–65
Hear when a new Effectiveness trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,360 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.