Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,374 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03883269RecruitingPhase 4
Tests topical antibiotics’ anti-inflammatory effect in acne
This trial studies whether putting antibiotic creams on mild-to-moderate facial acne reduces inflammation. It may help answer whether topical erythromycin or clindamycin can improve acne-related redness and swelling.
LeidenAges 18–45 - NCT03949400Recruiting
Exercise therapy and a soft knee brace for knee arthritis
This study tests whether an exercise program plus education, along with a soft brace, helps improve symptoms and function in adults with knee osteoarthritis. It may help people who have knee pain by combining movement training with daily support.
Aalborg, NothernAges 18 years+ - NCT03893734RecruitingPhase 4
Methadone vs hydromorphone to check heart rhythm after surgery
This trial tests whether the pain medicines methadone and hydromorphone affect the heart’s electrical timing after general anesthesia and surgery. It may help doctors choose the safer option for patients who need strong pain control after an operation.
Evanston, IllinoisAges 18–80 - NCT04087200Recruiting
High-dose statin early after heart attack to protect kidneys
This trial looks at whether starting a high dose of a statin (cholesterol medicine) right away after an acute coronary syndrome (a serious heart condition) can reduce future heart and kidney problems. It may help patients by testing a strategy meant to prevent complications soon after the event.
PratoAges Any age - NCT04098536Recruiting
Diesel exposure study of long-lasting inflammation and blood vessels
This study exposes healthy adults to diesel fumes to see how it affects inflammation (the body’s response to irritation) and blood vessels over time. It may help researchers understand health risks from diesel air pollution, though it is not for people with existing chronic health conditions.
Athens, AtticaAges 18–60 - NCT04209244Recruiting
Fish oil for cholesterol and side effects in ALL patients
This trial studies whether fish oil can improve cholesterol levels and reduce side effects in children and young adults with acute lymphoblastic leukemia (ALL) who are in lower-risk groups. If you fit the risk category, you may be asked to add fish oil as part of the study to see if it helps your lab results and well-being.
AalborgAges 1–45 - NCT04144439RecruitingPhase 4
GABA treatment for ADHD and seizures in children with epilepsy
This trial studies whether adding GABA (a substance that affects brain signaling) can help children who have both epilepsy (seizures) and ADHD. If it works, it may reduce symptoms related to either seizures, ADHD, or both.
TantaAges 4–18 - NCT04192656RecruitingPhase 4
PAP treatment for sudden hearing loss with sleep apnea
This trial tests whether using PAP (a breathing device for sleep apnea) can improve sudden hearing loss that happens alongside obstructive sleep apnea. It may help by reducing stress on the body during sleep and supporting hearing recovery.
Beijing, Beijing MunicipalityAges 18–70 - NCT04275453RecruitingPhase 1/Phase 2
Test diet vs ketone drinks to reach ketosis safely
This early-stage study compares how quickly and effectively a low-carbohydrate diet versus taking ketone supplements helps the heart use less sugar (measured with PET/CT scans). It also looks at how long it takes to reach a “ketosis” state, which may be helpful for metabolic health.
Philadelphia, PennsylvaniaAges 18 years+ - NCT02918188RecruitingPhase 2
Hydrogen therapy for steroid-resistant graft-versus-host disease
This Phase 2 study tests whether hydrogen therapy can improve symptoms in people with chronic graft-versus-host disease (cGVHD) who cannot tolerate steroid treatment. If steroids aren’t working or can’t be used, this trial may offer an alternative approach to help control the illness.
Beijing, Beijing MunicipalityAges Up to 65 years - NCT02836158RecruitingPhase 2/Phase 3
Test drug plus spinal chemotherapy for older PCNSL
This trial studies whether adding R-IDARAM and medication delivered into the spinal fluid can improve treatment for primary central nervous system lymphoma (PCNSL) in newly diagnosed older adults. It may help by targeting lymphoma cells in the brain, covering membranes, and spinal fluid.
Beijing, Beijing MunicipalityAges 60–75 - NCT04469387Recruiting
Reduce adjacent back pain after lumbar surgery
This trial looks at whether a limited decompression (a careful nerve-space “freeing” procedure) can help prevent future problems in the spinal level next to your planned surgery. It targets people with spinal canal narrowing next to the surgery level but who do not yet have symptoms there.
Beijing, Beijing MunicipalityAges 18–80 - NCT04581122Recruiting
Tests how lymph node surgery choices affect lung nodule outcomes
This study looks at whether different lymph node removal methods during lung surgery change outcomes for certain abnormal lung spots. It focuses on ground-glass nodules that stay the same after treatment-free observation and have a mostly solid portion on CT.
ShanghaiAges 18–75 - NCT04702321Recruiting
Study genetic risks for childhood cancer complications in Switzerland
This study looks at genetic factors to understand why some children who had cancer develop later complications. It uses stored samples and information from a Swiss biobank to help researchers identify higher-risk children.
GenevaAges Up to 21 years - NCT04483076RecruitingPhase 3
Chemo before stomach surgery with different cycles
This trial studies whether giving oxaliplatin plus S-1 (SOX) chemotherapy before stomach surgery works best when given for different cycle lengths. It may help shrink stage III gastric cancer before a standard D2 gastrectomy and improve outcomes.
Beijing, Beijing MunicipalityAges 18–70 - NCT04220047Recruiting
Surgery changes for preventing irregular heart rhythms during bypass
This trial studies whether removing a small heart pouch area and a specific ligament during off-pump heart bypass surgery improves outcomes. It is meant for people having their first off-pump coronary bypass, without a history of atrial fibrillation.
BeijingAges 18–80 - NCT04661449Recruiting
Lifestyle program for babies born larger than expected
This trial looks at whether a structured lifestyle program improves health and development outcomes for babies who were born larger than expected (large-for-gestational-age). If you qualify, the study may guide caregiver and family habits to support your child’s early outcomes.
Shanghai, Shanghai MunicipalityAges 1 day–1 month - NCT01604395Recruiting
Long-term growth hormone check for children with short stature
This study follows children who are short for their age and checks how safe and effective growth hormone is over the long term. It may help families understand expected benefits and side effects for their specific growth-related condition.
SeoulAges 2 years+ - NCT04799002RecruitingPhase 3
Topotecan and melphalan for eye-sparing retinoblastoma treatment
This trial studies whether a combination chemotherapy treatment (topotecan plus melphalan) can help children with retinoblastoma while keeping the eye when possible. It’s a Phase 3 study, meaning it’s testing effectiveness in a larger group of patients.
Guangzhou, GuangdongAges Any age - NCT04742478Recruiting
Study of atherectomy and ultrasound for heavily calcified heart arteries
This study looks at how safe and effective a treatment is for heart artery blockages that are heavily hardened by calcium. It enrolls people who need a procedure to open the artery (with or without a stent) and whose blockage matches specific imaging or access problems.
KitakyushuAges 21 years+ - NCT04893603Recruiting
TAVR valve test for severe, hard-to-pump heart valve
This trial studies whether a new through-the-blood-vessel heart valve (TAVR) is safe and works well for people with severe aortic stenosis who are too risky for traditional surgery. If you qualify, you would be closely followed to check your symptoms and valve function over time.
BeijingAges 70 years+ - NCT04905056RecruitingPhase 2
Ablation treatment for lung ground-glass nodules that don’t go away
This Phase 2 trial studies whether a procedure called “ablation” is safe and effective for certain lung cancers that appear as ground-glass spots on CT scans and do not improve after 3 months. It may help people who cannot fully have surgery for their condition.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT04888975Recruiting
Device study for one-arm swelling after lymph surgery
This study tests a medical device (Dayspring Technology) to reduce swelling in the arm caused by breast cancer treatment and lymph surgery. You may be eligible if you have one-sided arm swelling after lymphatic surgery and meet safety checks for the device.
Palo Alto, CaliforniaAges 18 years+ - NCT04989985RecruitingPhase 2
SOX chemotherapy plus immunotherapy for junction stomach-esophagus cancer
This trial studies whether adding an immunotherapy drug (sintilimab) to standard chemotherapy (S-1 and oxaliplatin) can better treat locally advanced cancer at the junction of the esophagus and stomach. It may help shrink the tumor and control the cancer before or around surgery.
Guangzhou, GuangdongAges 18–75
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,374 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.