Methadone vs hydromorphone to check heart rhythm after surgery
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether the pain medicines methadone and hydromorphone affect the heart’s electrical timing after general anesthesia and surgery. It may help doctors choose the safer option for patients who need strong pain control after an operation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for an elective surgery needing general anesthesia.
- You expect moderate to severe pain after surgery.
- You do NOT have a history of heart rhythm problems, and you do not have a pacemaker or defibrillator.
- You are not allergic to methadone or hydromorphone.
- Your blood salt (electrolyte) levels are normal before surgery.
- You do NOT have significant heart valve disease, and your heart rhythm is normal (sinus rhythm).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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