Clinical trials
Endometrioid Endometrial Cancer clinical trials
Below are recruiting endometrioid endometrial cancer clinical trials, each written for real people, not researchers. We’re tracking 76 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06468215Recruiting
Fertility-sparing treatment for early stage 2 endometrial cancer
This study tests a way to treat early-stage endometrial cancer without removing the uterus, so you can still have a chance to carry a pregnancy. It’s for women under 45 with a grade 2 tumor that hasn’t grown into the womb muscle.
Beijing, Beijing MunicipalityAges Up to 45 years - NCT06206083Recruiting
Studying endometrial cancer types to predict outcomes
This study looks at the specific type of endometrial cancer (endometrioid) in Mexican patients to understand how different molecular features affect prognosis. It may help doctors better tailor treatment to the individual.
Mexico City, Mexico CityAges 18 years+ - NCT07025213Recruiting
Exercise and diet study for endometrial cancer before surgery
This study tests whether combining exercise with a special diet can improve how your body processes energy (metabolism) before you have surgery to remove the cancer. It is for people with early-stage endometrial cancer who haven't yet started treatment.
México, TlalpanAges 18–65 - NCT07198074RecruitingPhase 3
Testing Avastin added to chemo plus Keytruda for certain endometrial cancer
This study tests adding Avastin (bevacizumab) to the standard combination of chemotherapy (carboplatin and paclitaxel) plus immunotherapy (Keytruda) for advanced or recurrent endometrial cancer with a specific genetic makeup (pMMR and TP53 mutation). The goal is to see if adding Avastin helps shrink tumors or slow their growth.
Birmingham, AlabamaAges 18 years+ - NCT07258186Recruiting
Endometrial cancer organoid study
This study creates miniature 3D versions of endometrial cancer tumors (organoids) from tissue samples taken during surgery. The goal is to better understand the disease and find personalized treatments.
Roma, RomaAges 18 years+ - NCT06841653Recruiting
AI model to predict risk and improve treatment for endometrial cancer
This trial is testing whether a computer model powered by artificial intelligence can better predict outcomes for people with endometrial cancer or related conditions. It uses patient data and tissue samples to see if the model can help doctors choose the best care.
RomeAges 18 years+ - NCT07041606Recruiting
A study on advanced endometrial cancer in Russia
This study looks at genetic profiles and first treatments for advanced or aggressive endometrial cancer in women in Russia. It aims to understand how genetic information might guide better treatment choices.
ArkhangelskAges 18 years+ - NCT07594015RecruitingPhase 2
Pembrolizumab and Lenvatinib for Recurrent Endometrial Cancer
This trial tests a combination of two drugs (pembrolizumab and lenvatinib) for endometrial cancer that has come back after initial treatment with chemotherapy and immunotherapy. The study focuses on a specific type of cancer based on genetic testing and may help patients whose cancer didn't respond to standard first-line treatment.
Miami, FloridaAges 18 years+ - NCT06855706Recruiting
Personalized physical activity program for ovarian and endometrial cancers
This study tests whether a personalized, automated physical activity program (using a Fitbit and continuous glucose monitor) can improve immune function and health outcomes in people with advanced ovarian, primary peritoneal, fallopian tube, or newly diagnosed endometrial cancer. You'll wear an activity tracker, answer questionnaires, and provide blood and stool samples at Roswell Park.
Buffalo, New YorkAges 18 years+ - NCT05247268RecruitingPhase 2
Hormone therapy to shrink early uterine cancer in young women
This trial tests whether combining two hormone medicines can treat early endometrial (uterine) cancer while helping preserve the uterus and future fertility. You may be eligible if your cancer is early and limited, with no spread seen on scans, and you can safely take these medicines.
ShanghaiAges 18–45 - NCT06603506Recruiting
Testing PARP inhibitors on your endometrial cancer cells
This study is testing whether a special kind of medicine called a PARP inhibitor can work against endometrial cancer cells grown in a lab from your tumor. The goal is to find out which patients might benefit from this treatment in the future.
CaenAges 18 years+ - NCT04469764RecruitingPhase 2
Abemaciclib for certain recurrent ovarian or endometrial cancers
This Phase 2 study tests abemaciclib, a targeted pill treatment, for recurrent ovarian or endometrial cancer that shows specific tumor genetic patterns. It may help slow or control cancer growth in people whose tumor matches the required test results.
Los Angeles, CaliforniaAges Any age - NCT03463252RecruitingPhase 2/Phase 3
Hormone IUD to preserve fertility in early uterine cancer
This study looks at whether a hormone-releasing IUD (LNG-IUS) can treat early-stage endometrial cancer or very early abnormal cell growth while helping you keep the option for future pregnancy. It aims to see how well the treatment works and how it affects fertility-related outcomes.
Chengdu, SichuanAges Up to 40 years - NCT06417736Recruiting
Study on Endometrial Cancer and Precancer in Young Women
This study tests whether certain treatments can help women aged 18-45 with early-stage endometrial cancer or precancerous changes keep their ability to have children. It uses imaging scans to make sure the cancer hasn't spread.
Hangzhou, ZhejiangAges 18–45 - NCT07318324RecruitingPhase 1
Study of three drugs for advanced endometrial cancer with RAS mutations
This trial tests a combination of three targeted drugs (avutometinib, defactinib, and everolimus) for people whose endometrial cancer has a specific change in the RAS pathway and has not responded to other treatments. The goal is to see if this drug combo can shrink tumors or slow their growth.
Houston, TexasAges 18 years+ - NCT07631572Recruiting
Cesium implant radiation for recurrent cervical or uterine cancer
This study tests a type of internal radiation (cesium implant) to treat cancer that has come back in the vagina after previous pelvic radiation. The goal is to save the organ while treating the cancer.
Lexington, KentuckyAges 18 years+ - NCT04196257RecruitingPhase 1
Early-dose trial of BP1001-A for advanced or recurrent solid tumors
This Phase 1 trial studies BP1001-A in people with advanced or recurring solid cancers to find a safe dose and learn how the treatment works. You may be asked for tumor biopsies before and possibly after treatment to see how the cancer responds.
Silver Spring, MarylandAges 18 years+ - NCT07139977RecruitingPhase 2
Study of EV for recurrent endometrial cancer
This trial tests a drug called EV for people with recurrent endometrial cancer that has gotten worse after treatment. It may help if your cancer cells have a specific protein called nectin-4.
Milwaukee, WisconsinAges 18 years+ - NCT07377734RecruitingPhase 2
Collagen injection before fertility-sparing therapy for early endometrial cancer
This trial tests whether an injection of type III collagen into the uterus before standard progestin therapy can help preserve fertility in women with very early endometrial cancer or atypical hyperplasia. It is designed for women who want to keep the option of having children.
BeijingAges 18–45 - NCT04008563Recruiting
Weight-loss surgery to protect fertility in early womb cancer
This study tests whether bariatric (weight-loss) surgery can help treat certain early, low-grade womb changes while preserving fertility. It’s mainly for people with a higher BMI who want to have children and have an early stage diagnosis confirmed by scans.
Toronto, OntarioAges 18–41 - NCT07107334RecruitingPhase 2
GLP-1 drug plus hormone IUD for early endometrial cancer in obesity
This trial tests if adding a GLP-1 weight-loss drug to a hormone-releasing IUD can help treat very early endometrial cancer or a precancerous condition in women with obesity. The goal is to see if this combination is effective without surgery.
Gainesville, FloridaAges 18 years+ - NCT07319429RecruitingPhase 2/Phase 3
Fertility-sparing treatment for endometrial cancer based on molecular type
This trial tests a tailored approach to preserve fertility in women with early-stage endometrial cancer, using medications like hormones and immunotherapy based on the tumor's molecular subtype. It aims to avoid hysterectomy and keep the uterus intact.
Shanghai, Shanghai MunicipalityAges 18–45 - NCT06348719Recruiting
Robot vs. standard laparoscopy for early endometrial cancer
This trial compares two types of minimally invasive surgery (robot-assisted vs. conventional laparoscopy) for removing the uterus in people with early-stage, low- to intermediate-risk endometrial cancer. The goal is to see which approach offers the best value and outcomes.
LilleAges 18 years+ - NCT03785288RecruitingPhase 3
Testing different schedules of vaginal radiation after hysterectomy
This trial compares different “fractionation” schedules (how often and how many treatments) of vaginal brachytherapy radiation given after surgery for certain early-stage endometrial cancer. It may help find a plan that works well while aiming to control side effects.
Baltimore, MarylandAges 18 years+
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Common questions
- Are there clinical trials for endometrioid endometrial cancer?
- Yes. Clin2 currently lists 76 recruiting endometrioid endometrial cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a endometrioid endometrial cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a endometrioid endometrial cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.