Clinical trials
Epilepsy, Generalized clinical trials
Below are recruiting epilepsy, generalized clinical trials, each written for real people, not researchers. We’re tracking 17 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06388174Recruiting
Idiopathic Generalized Epilepsy Study
This study is looking at people with a specific type of epilepsy called idiopathic generalized epilepsy (IGE). The goal is to collect health information and use a 24-hour brain wave test to learn more about the condition.
Hangzhou, ZhejiangAges 4–40 - NCT06769659RecruitingPhase 2
Testing NPT 2042 for absence seizures in genetic epilepsy
This trial tests a new medication called NPT 2042 for people with a type of epilepsy that causes brief staring spells (absence seizures). It aims to see if the drug can reduce seizure frequency compared to a placebo (an inactive pill).
Little Rock, ArkansasAges 16–75 - NCT07680842Recruiting
Non-invasive ultrasound for drug-resistant epilepsy
This study tests a non-invasive focused ultrasound treatment for people with epilepsy that doesn't respond to medications. The goal is to see if this gentle ultrasound can reduce seizures without surgery.
San Francisco, CaliforniaAges 21–65 - NCT05673915Recruiting
Brain stimulation study for hard-to-control epilepsy
This trial tests whether noninvasive brain stimulation (using gentle electrical current through the scalp) can reduce seizures in people with epilepsy that has not responded to at least two anti-seizure medicines. If you qualify, you’d also be asked to keep track of seizures in a diary during the study.
Rochester, MinnesotaAges 6 years+ - NCT07012148Recruiting
Seizure forecasting with EEG and wearables for epilepsy
This study tests a wearable device that records brain waves to help predict and track seizures in people with temporal lobe epilepsy. It may help you better understand your seizure patterns and reduce uncertainty.
Rochester, MinnesotaAges 18–75 - NCT06579573RecruitingPhase 3
Testing a new drug for generalized tonic-clonic seizures in Japan
This study tests a new medicine (ONO-2017) for people with a type of epilepsy that causes whole-body seizures. It looks at whether adding this drug to your current seizure medicines can reduce how often those seizures happen.
AichiAges 12 years+ - NCT06782074Recruiting
Epilepsy's impact on thinking and emotions in teens
This study looks at how idiopathic generalized epilepsy affects thinking skills and emotions in adolescents aged 11 to 18. It aims to better understand these effects to improve care.
PaviaAges 11–17 - NCT06399952Recruiting
Natural history study for Baker Gordon syndrome
This study follows people with Baker Gordon syndrome over time to better understand the condition. Participants and their caregivers share medical records and complete tests and questionnaires.
Columbia, MissouriAges birth–99 years - NCT06908356RecruitingPhase 2
Testing PRAX-628 for focal or tonic-clonic seizures
This study tests an experimental pill called PRAX-628 for adults whose seizures are not fully controlled by current medications. It aims to see if the drug is safe and effective at reducing seizures.
Phoenix, ArizonaAges 18–75 - NCT06792383Recruiting
Psychological and psychiatric assessment before epilepsy surgery
This study evaluates psychological and psychiatric well-being in adults with drug-resistant epilepsy who are being considered for surgery. It aims to understand factors that may affect outcomes and patient experience.
MilanAges 18 years+ - NCT07287163Enrolling by invitationPhase 3
Long-term study of vormatrigine for epilepsy
This trial is for adults with epilepsy who have already taken vormatrigine in a previous study or through a special access program. It aims to collect ongoing safety and effectiveness information.
Miami, FloridaAges 18–85 - NCT06974305Recruiting
Brain imaging study for epilepsy
This study uses PET, MRI, and EEG scans to learn more about epilepsy. It may help researchers understand how the brain works in people with epilepsy and in healthy volunteers.
Charlestown, MassachusettsAges 18 years+ - NCT05393518Recruiting
Study linking brain signals to anxiety in people with epilepsy
This study looks at how brain electrical signals relate to anxiety symptoms in people with drug-resistant epilepsy. It compares people who do (or do not) meet criteria for generalized anxiety disorder, to better understand anxiety in this setting.
BordeauxAges 18–65 - NCT06716801Recruiting
How cenobamate works as early add-on treatment for epilepsy
This study looks at how well cenobamate works when added to other seizure medications for adults with focal epilepsy. It uses real-world data from medical records to see how people respond to treatment.
Paris, FranceAges 18 years+ - NCT06292494Recruiting
Focused ultrasound for drug-resistant epilepsy
This trial tests whether focused ultrasound can help people whose seizures are not controlled by two or more medications. You would have a noninvasive procedure while awake, pressing a stop button if needed, and your hair will be partially shaved.
TaipeiAges 18 years+ - NCT05222594Recruiting
Brain language study using electrodes during epilepsy care
This study looks at how the brain processes language using recordings from electrodes placed during epilepsy treatment. If you’re already being considered for this type of brain monitoring, the study’s tasks may help researchers better understand language function in the brain.
Boston, MassachusettsAges 18–85 - NCT04788628Enrolling by invitation
Sound stimulation study for sleep and memory in epilepsy
This trial studies whether carefully timed sound (“auditory stimulation”) can change sleep patterns and memory in people with epilepsy. It may help researchers understand how to improve thinking and memory by adjusting how the brain sleeps.
Boston, MassachusettsAges 12–65
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Common questions
- Are there clinical trials for epilepsy, generalized?
- Yes. Clin2 currently lists 17 recruiting epilepsy, generalized studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy, generalized trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy, generalized trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.