Clinical trials
Epilepsy, Temporal Lobe clinical trials
Below are recruiting epilepsy, temporal lobe clinical trials, each written for real people, not researchers. We’re tracking 22 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06521437Enrolling by invitation
How the brain's memory center works in epilepsy
This study looks at how the hippocampus (a part of the brain important for memory) works in people with epilepsy. If you have a hard-to-treat type of epilepsy called MTLE, this research may help doctors understand memory and brain function better.
Chicago, IllinoisAges 18 years+ - NCT05608408Recruiting
Preserving Memory in People With Epilepsy Using Brain Stimulation
This study tests a type of brain stimulation in people with epilepsy to see if it can help preserve memory. Researchers will compare memory and brain effects over time to understand whether stimulation changes memory outcomes.
Rochester, MinnesotaAges 18–65 - NCT03478852Recruiting
Epilepsy screening and evaluation for people 8 and older
This study checks how people with known or suspected epilepsy are evaluated and followed. It may help by improving screening and understanding care for epilepsy in children and adults.
Bethesda, MarylandAges 8–110 - NCT04649008RecruitingEarly Phase 1
MRI and brain electrodes to map epilepsy areas
This early study looks at how MRI scans and implanted brain electrodes (intracranial EEG) can pinpoint where seizures start, especially in the temporal (side) lobe. It may help doctors better localize seizure sources for people whose seizures don’t respond well to medications.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05135091RecruitingPhase 3
Cell therapy trial for hard-to-control one-sided temporal lobe epilepsy
This Phase 3 study tests a neural cell therapy (NRTX-1001) for adults whose seizures come from one side of the hippocampus and have not improved with standard seizure medicines. The goal is to reduce seizure frequency and improve seizure control where other treatments have not worked.
Birmingham, AlabamaAges 18–75 - NCT05339438Recruiting
Brain scan mapping before epilepsy surgery
This study uses a special MRI scan to map parts of the front-temporal brain in people with drug-resistant epilepsy who may need surgery. The goal is to better plan surgery by showing which brain areas are involved.
NancyAges 18 years+ - NCT05609084Recruiting
Speech therapy before surgery for drug-resistant temporal epilepsy
This study tests an intensive pre-surgery speech rehabilitation program for people whose seizures come from the language-related area in the temporal part of the brain. The goal is to improve speech outcomes before planned epilepsy surgery.
BordeauxAges 16 years+ - NCT05947656Recruiting
NaviFUS treatment for drug-resistant temporal lobe seizures
This trial tests the NaviFUS system to treat seizures that keep happening despite seizure medicines, specifically in people with temporal lobe epilepsy. If you qualify, you would be carefully checked before and during the study, including seizure tracking and brain scans, to see whether treatment helps reduce seizures.
Melbourne, VictoriaAges 18 years+ - NCT06063850RecruitingPhase 1/Phase 2
Gene therapy for adults with hard-to-control epilepsy
This trial tests a one-time gene therapy (AMT-260) for adults whose seizures start in one area of the brain (the temporal lobe) and aren't controlled by medication. The goal is to see if it's safe and reduces seizure frequency.
Birmingham, AlabamaAges 18–75 - NCT06422923RecruitingPhase 1/Phase 2
Cell therapy for hard-to-treat epilepsy starting in both temporal lobes
This trial tests a new cell therapy (NRTX-1001) for people with epilepsy that starts in both sides of the brain's temporal lobes and doesn't get better with medication. It aims to reduce or stop seizures.
Little Rock, ArkansasAges 18–75 - NCT06466681Recruiting
Attention changes after a seizure in epilepsy
This study looks at how attention and concentration change right after a seizure in people with epilepsy. It uses a short hospital stay to track these changes, which may help improve understanding and future treatment.
LilleAges 18–80 - NCT06483061RecruitingPhase 2
Enhanced MRI Study for Epilepsy and Healthy Volunteers
This study tests whether a special MRI contrast agent (Ferumoxytol) can improve brain imaging in healthy people and people with temporal lobe epilepsy. It may help doctors see more detail in the brain.
Edmonton, AlbertaAges 18–64 - NCT06492720Recruiting
Testing focused ultrasound for drug-resistant epilepsy
This study tests a new device called NaviFUS that uses focused sound waves to gently stimulate a small area of the brain. It is for people whose seizures start in one part of the brain and are not fully controlled by seizure medicines.
TaipeiAges 18–65 - NCT07202494Recruiting
Brain aging and resilience MRI study
This study uses powerful MRI scans to understand how the brain ages and why some people stay healthy while others develop neurological diseases like multiple sclerosis or Alzheimer's. It compares healthy volunteers to people with certain conditions, and all participants get a detailed brain MRI.
MarseilleAges 18–90 - NCT07244328RecruitingEarly Phase 1
UX-GIP001 cell therapy for drug-resistant temporal lobe epilepsy
This trial tests a new cell therapy, UX-GIP001, for people whose seizures start in one small area of the brain (the mesial temporal lobe) and are not controlled by at least two seizure medications. The goal is to see if this treatment can safely reduce seizures.
Hangzhou, ZhejiangAges 18–75 - NCT01273129Recruiting
Surgery for epilepsy that medicines cannot control
This trial looks at using brain surgery to treat epilepsy that does not improve with usual medicines, or epilepsy caused by a brain tumor. It may help some people reduce seizures if surgery is appropriate for their situation.
Bethesda, MarylandAges 8–99 - NCT02151175Enrolling by invitation
Focused ultrasound to treat medication-resistant temporal lobe seizures
This trial tests a low-intensity focused ultrasound treatment aimed at reducing seizures caused by problems in one side of the hippocampus (a brain area involved in memory and seizures). It’s for people whose seizures have not responded to several seizure medicines and who have been offered a specific type of surgery.
Los Angeles, CaliforniaAges 18–60 - NCT07580183Recruiting
Memory and Brain Function in Epilepsy Surgery
This study examines how the brain recognizes spatial scenes (like rooms or landscapes) in people with epilepsy who may have surgery. Researchers want to understand memory patterns before and after surgery to help predict outcomes.
Sacramento, CaliforniaAges 18–55 - NCT04717388Recruiting
Study brain and feelings in people with tinnitus
This study looks at how tinnitus affects the brain, thinking, and emotional well-being. It compares people with chronic tinnitus to people without tinnitus (including a group related to a specific type of epilepsy surgery).
ParisAges 18 years+ - NCT06720922Recruiting
Laser surgery for drug-resistant epilepsy
This trial tests a new, less invasive surgery called MRI-guided laser ablation (MRgLITT) for people with drug-resistant mesial temporal lobe epilepsy. It aims to stop or reduce seizures by using a laser to destroy the tiny area of the brain causing them.
Beijing, Beijing MunicipalityAges Any age - NCT07226908Enrolling by invitation
Brain electrode study for epilepsy and memory
This study places electrodes in the brain to learn how seizures spread and how memory works. It may help people with temporal lobe epilepsy understand their condition better and improve future treatments.
Stanford, CaliforniaAges 18–65 - NCT07608588Recruiting
Brain Stimulation for Language Recovery After Stroke
This study tests whether a non-invasive brain stimulation technique called rTMS can help people regain language skills after a left-sided stroke, particularly for word-finding and meaning difficulties. Researchers will target specific brain regions to see if stimulation improves recovery.
Columbia, South CarolinaAges 18 years+
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Epilepsy, Temporal Lobe trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for epilepsy, temporal lobe?
- Yes. Clin2 currently lists 22 recruiting epilepsy, temporal lobe studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy, temporal lobe trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy, temporal lobe trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.