Clinical trials
Fatigue clinical trials
Below are recruiting fatigue clinical trials, each written for real people, not researchers. We’re tracking 293 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06873464Enrolling by invitation
Brain stimulation to reduce fatigue in multiple sclerosis
This trial tests if a gentle brain stimulation technique (tDCS) can help reduce fatigue and improve quality of life for people with multiple sclerosis. You would receive either real or placebo stimulation over several sessions to see if it helps you feel less tired.
MadridAges 18–75 - NCT06877403Enrolling by invitation
Fatigue study in myasthenia gravis patients
This study looks at how common and how severe fatigue is in people with myasthenia gravis. It aims to understand the impact of fatigue on daily life and may help improve care for patients with this condition.
Clermont-FerrandAges 18 years+ - NCT06860880Recruiting
Personalized program to fight cancer-related fatigue
This trial tests a personalized supportive care program that combines exercise, nutrition, and coaching to help reduce fatigue in people with certain slow-growing lymphomas. It aims to improve energy and quality of life.
Chapel Hill, North CarolinaAges 18 years+ - NCT06855524RecruitingPhase 2
Seaweed supplement for less fatigue during chemotherapy
This study tests whether fucoidan, a supplement from brown seaweed, can help reduce fatigue caused by chemotherapy. Doctors at Mayo Clinic want to see if taking fucoidan during chemo helps you feel less tired.
Scottsdale, ArizonaAges 18 years+ - NCT06851091Recruiting
Fibromyalgia study on pain sensitivity and balance
This study looks at how fibromyalgia affects your sensitivity to pain and your sense of balance. It may help find better ways to treat these symptoms.
Istanbul, ÜsküdarAges 18–65 - NCT06809192Recruiting
Cognitive behavioral therapy for multiple sclerosis fatigue
This study will test different parts of cognitive behavioral therapy to see which ones help with fatigue in people with multiple sclerosis. You will participate in sessions that may involve changing thoughts about fatigue, scheduling activities, or addressing related emotions like depression or anxiety.
Seattle, WashingtonAges 18 years+ - NCT06810817Recruiting
Brain stimulation and talk therapy for post-stroke fatigue
This trial tests whether a combination of gentle brain stimulation (tDCS) and a talking therapy program can help reduce fatigue after a stroke. It aims to find a safe, non-drug way to improve energy and quality of life for stroke survivors.
Hong KongAges 50–80 - NCT05866952Recruiting
Breathing and blood-flow testing in long-COVID symptoms
This trial studies how the lungs’ breathing (airflow) and blood flow may be off in people with long-COVID symptoms like tiredness, shortness of breath, or trouble exercising. It may help researchers understand what’s driving symptoms and what kinds of abnormalities could be targeted.
Boston, MassachusettsAges 18–99 - NCT06789003Recruiting
Prehabilitation with exercise for multiple myeloma patients
This trial tests whether a prehabilitation program using adapted physical activity can help multiple myeloma patients prepare for a stem cell transplant. It may improve your strength and recovery before and after the transplant.
AvignonAges 18 years+ - NCT06754722Recruiting
EnergyPoints app for cancer-related fatigue
This trial tests an app called EnergyPoints that may help reduce fatigue in people who have or have had cancer. You would use the app and wear a Fitbit to track your activity.
New York, New YorkAges 18 years+ - NCT05762250Recruiting
Ear acupuncture for symptom relief in advanced cancer
This study tests whether auricular (ear) acupuncture can reduce ongoing symptoms and daily limitations in people with advanced cancer. It may help with discomfort and other side effects related to the disease or its treatment.
StuttgartAges 18–70 - NCT06743490Recruiting
Tracking MG symptoms with smartphone recordings
This study uses your smartphone to record symptoms like slurred speech, hoarseness, arm fatigue, or droopy eyelids, making it easier for doctors to understand and monitor myasthenia gravis. Both people with MG and healthy volunteers can take part.
Leiden, South HollandAges 18 years+ - NCT06736002Recruiting
Vitamin D for epilepsy: fewer seizures, less fatigue
This trial tests whether high doses of vitamin D can help reduce seizures and improve fatigue and quality of life in adults with refractory epilepsy who have not responded well to at least two medications.
TainanAges Any age - NCT06699134Recruiting
Study on Hi-Fatigue G Bone Cement in Knee or Hip Replacement
This study looks at how well a specific bone cement (Hi-Fatigue G) works in people who have had a knee or hip replacement. It aims to help doctors understand if this cement is a good option for holding the artificial joint in place.
Weiden, BavariaAges 18 years+ - NCT06675344Recruiting
A device for fatigue, Raynaud's, and quality of life in scleroderma
This trial tests if a device called Apollo can help reduce fatigue and Raynaud's symptoms and improve quality of life in people with scleroderma (systemic sclerosis). You would use the device at home and track your symptoms using a smartphone app.
New Orleans, LouisianaAges 18 years+ - NCT06650813Recruiting
Adapting a fatigue program for sickle cell disease
This trial adapts the FACETS program, a fatigue-management course, for people with sickle cell disease. It aims to help participants better cope with fatigue and improve daily life.
GrenobleAges 18 years+ - NCT06633224Recruiting
Fatigue and biology in cancer patients getting chemoradiation
This study looks at why some people feel very tired during cancer treatment. Researchers will collect blood and stool samples to study how the body responds to chemotherapy and radiation.
San Francisco, CaliforniaAges 18 years+ - NCT06126627Recruiting
Brain and voice study for teachers with vocal fatigue
This study looks at how vocal fatigue affects the brain and voice in teachers. It uses MRI and voice tests to understand these changes.
BonnAges 21–39 - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06567704Recruiting
Fatigue from immunotherapy in lung cancer: a patient interview study
This study aims to understand how maintenance immunotherapy affects fatigue in people with non-small cell lung cancer. Researchers will talk with patients to learn about their experiences.
Charlotte, North CarolinaAges 18 years+ - NCT06562283Recruiting
Reproducibility of a fatigue test for spinal muscular atrophy
This study checks how consistent a fatigue test is for people with spinal muscular atrophy (SMA). It helps doctors better understand fatigue in SMA and may improve future care.
Saint-Etienne, FranceAges 6 years+ - NCT06511518Recruiting
Talking therapy for fatigue in advanced cancer
This study tests whether cognitive behavioral therapy, a type of talking therapy, can help reduce severe fatigue in people with advanced solid tumors or gliomas who are receiving or have completed palliative treatment. The goal is to see if this approach improves energy levels and quality of life.
Amsterdam, North HollandAges 18 years+ - NCT06472622RecruitingEarly Phase 1
Brain imaging study of pain and effort
This study uses brain scans to understand how people experience pain and effort. It compares healthy volunteers to people with ME/CFS to see if there are differences in brain activity.
Bethesda, MarylandAges 18–50 - NCT06475339Recruiting
Heat and exercise study for healthy active adults
This study looks at how healthy, active people respond to repeated exercise in hot conditions. It will help researchers understand how your body handles heat and fatigue during demanding physical tasks.
Buffalo, New YorkAges 18–39
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Common questions
- Are there clinical trials for fatigue?
- Yes. Clin2 currently lists 293 recruiting fatigue studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a fatigue trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a fatigue trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.