Clinical trials
Muscle Fatigue clinical trials
Below are recruiting muscle fatigue clinical trials, each written for real people, not researchers. We’re tracking 33 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07405060Recruiting
How age and muscle fatigue affect balance and control
This study looks at how getting older and muscle tiredness change your ability to keep your balance and control your movements. It may help explain why some people are more likely to fall.
TaoyuanAges 20–85 - NCT06217276Recruiting
Breathing muscle fatigue and leg oxygen in COPD
This study looks at how breathing muscle tiredness relates to oxygen levels in leg muscles for people with moderate-to-severe COPD. It may help patients understand their condition better.
Istanbul, ZeytinburnuAges 18–75 - NCT07602933Recruiting
Light Therapy for Muscle Fatigue from Electrical Stimulation
This study tests whether light therapy can reduce muscle fatigue and damage caused by electrical muscle stimulation. Researchers want to see if this non-invasive light treatment helps muscles recover faster.
Porto Alegre, Rio Grande do SulAges 18–45 - NCT07224646Recruiting
Light therapy for professional soccer players during a championship
This trial tests if a type of light therapy (called photobiomodulation) on the whole body can help professional soccer players recover faster and perform better during a championship. It involves 8 weeks of sessions alongside your regular training.
Porto Feliz, São PauloAges 18–35 - NCT06529055Enrolling by invitation
Caffeine and nicotine pouch effects on exercise and brain function
This trial tests how caffeine and nicotine pouches affect your body during exercise, including heart function, thinking, and behavior. It looks at short bursts of high-intensity activity in healthy men who already exercise regularly.
Hattiesburg, MississippiAges 21–40 - NCT06458166Recruiting
Youth soccer fatigue and jump performance study
This study looks at how tired muscles get after a soccer match and how that affects jumping ability and how you feel. It may help coaches understand recovery needs in young elite players.
Maia, Porto DistrictAges 16–21 - NCT05013255RecruitingPhase 2
Pioglitazone to treat fatigue in hormone-positive breast cancer
This Phase 2 study tests whether pioglitazone can reduce fatigue in people with certain types of breast cancer. You may be eligible if your cancer is estrogen- and progesterone-positive (ER+/PR+) and you plan surgery soon.
Morgantown, West VirginiaAges 18 years+ - NCT07273097Recruiting
Ankle muscle fatigue and walking in ankle instability
This trial studies how tired ankle muscles affect walking in people with chronic ankle instability. It compares their walking patterns to healthy people to understand if fatigue makes ankle issues worse.
LjubljanaAges 18–45 - NCT04899635Recruiting
Study tests heart muscle function during open-heart surgery
This study looks at how strong the heart muscle squeezes (contractility) using heart tissue from people having planned open-heart surgery. It may help researchers better understand “myocardial fatigue” to improve future heart care.
CoventryAges 18–85 - NCT07014111Recruiting
Fight Fatigue: muscle relaxation and walking for dialysis patients
This study tests a simple program that combines muscle relaxation exercises and walking to help reduce fatigue in people with end-stage kidney disease who are on dialysis. You'll receive text messages to guide you and track your progress.
Chicago, IllinoisAges 18 years+ - NCT07715292Enrolling by invitation
Muscle vibration during cycling exercise study
This trial tests whether applying gentle vibrations to your leg muscles during cycling can boost power and muscle activity. You will do a series of cycling tests while the vibration is on or off.
Wroclaw, Lower Silesian VoivodeshipAges 18–26 - NCT07547566Recruiting
TECAR Therapy vs. Cycling for Athletic Recovery
This study compares two recovery methods—TECAR therapy (a heating treatment) and cycling—to see which helps young athletes recover better after jumping exercises. The goal is to understand which approach reduces fatigue and helps athletes bounce back faster.
Córdoba, CórdobaAges 18 years+ - NCT06321965Recruiting
Study of SMA in Children on SMN-Boosting Therapies
This study is looking for children and teens with spinal muscular atrophy (SMA) who are already on a treatment like Spinraza, Evrysdi, or Zolgensma. The goal is to understand different forms of SMA and how the treatment affects them over time.
Bron, RhoneAges birth–16 years - NCT07604948Recruiting
Blood Flow Restriction Training for Basketball Recovery
This study tests whether briefly restricting blood flow to the legs (using an arm cuff on the thigh) can help male basketball players recover faster and improve leg strength after games. Researchers want to see if this technique, called ischemic preconditioning, reduces fatigue and speeds healing.
Guangzhou, GuangdongAges 18–25 - NCT06937190Recruiting
Does creatine before sleep improve power in active women?
This study tests if taking a small dose of creatine before bed helps women who exercise regularly perform better on power-based activities like jumping and sprinting. It's designed for healthy, young women who already do resistance training and want to see if a simple supplement can boost their nighttime recovery and next-day performance.
Shabestar, East Azerbaijan ProvinceAges 18–25 - NCT07659301Recruiting
Breathing extra oxygen after cycling to speed recovery
This study tests how breathing higher-than-normal levels of oxygen for a short time after a hard bike ride affects your recovery. It is designed for competitive road cyclists who want to recover faster and perform better in their next training or race.
Louvain-la-Neuve, Brabant-WallonAges 18–40 - NCT03940911Recruiting
Testing fatigue and muscle effects after starting targeted therapy
This study looks at how starting “targeted” treatment affects fatigue and skeletal muscle function in people with severe axial spondyloarthritis. It may help doctors understand what to expect early after treatment starts and how well it impacts day-to-day energy and muscle performance.
Strasbourg, Bas-RhinAges 18 years+ - NCT07331012Recruiting
Flywheel exercise for better basketball skills in teens
This study tests if upper body flywheel exercises can improve basketball skills, muscle oxygenation, and reduce fatigue in adolescent male basketball players. Flywheel exercises use a spinning wheel to create resistance during movement.
IğdırAges 10–18 - NCT07619209Recruiting
Relaxation exercises for cancer patients with breathing difficulty
This study tests whether gentle muscle relaxation and deep breathing exercises help cancer patients in palliative care feel less breathless, less tired, and better able to care for themselves. You would learn and practice these exercises and answer questions about how you feel.
Ankara, YENIMAHALLEAges 18 years+ - NCT07729930Recruiting
Creatine supplement study for healthy middle-aged women
This study is testing a creatine supplement (a substance that may help with energy and muscle function) in healthy middle-aged women. You may join if you are between 35 and 65, a non-smoker, and have a certain activity level.
LoughboroughAges 35–65 - NCT07094334Recruiting
Training on balance and fatigue using mental imagery
This trial tests if a single session of watching and imagining arm movements can improve balance and reduce fatigue in healthy young men.
AnkaraAges 18–25 - NCT05926219Recruiting
Study C-protein changes with fatigue and aging
This study looks at how a blood protein called C-protein relates to fatigue and aging, and how exercise affects it. You may be able to join if you’re otherwise healthy and willing to do muscle testing and activity monitoring.
Eugene, OregonAges 18–80 - NCT04142047Recruiting
Study muscle energy and fatigue in older adults
This study measures how older adults’ muscles use energy and how easily they tire during activity. It includes both people with HIV (with stable treatment and an undetectable viral load) and people without HIV to better understand differences in fatigue.
Baltimore, MarylandAges 60–90 - NCT06920095Enrolling by invitation
Relaxation exercises for better sleep and less pain in lymphoma
This trial tests if progressive muscle relaxation exercises can help lymphoma patients sleep better, feel less tired, and have less pain. You will be guided through simple exercises using your phone.
Küçükçekmece, IstanbulAges 18 years+
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Common questions
- Are there clinical trials for muscle fatigue?
- Yes. Clin2 currently lists 33 recruiting muscle fatigue studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle fatigue trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle fatigue trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.