Clinical trials
Fatigue clinical trials
Below are recruiting fatigue clinical trials, each written for real people, not researchers. We’re tracking 293 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06786832Recruiting
Trial for fatigued patients in primary care
This trial studies severe fatigue that started at a specific time and is not due to another illness. It aims to find better ways to diagnose, treat, and support people with long-term fatigue in primary care.
Stockholm, GustavsbergAges 18–67 - NCT06941701Recruiting
Fatigue's effect on thinking and movement together
This study looks at how being physically tired affects your ability to think and perform tasks at the same time. It may help understand why dual-tasking gets harder when you're fatigued.
IslamabadAges 18–30 - NCT07135791Recruiting
Tracking daily fatigue in adults with brain injury or cerebral palsy
This study uses a smartphone app to track how fatigue changes throughout the day in adults with cerebral palsy or acquired brain injury. The goal is to better understand fatigue patterns so doctors can offer better support.
Glostrup MunicipalityAges 30–65 - NCT07726082Recruiting
A group program to help with long-term fatigue
This study tests a new way to help people with long-term fatigue that gets in the way of daily life. It uses a group program that focuses on making small, helpful choices to feel better.
BaselAges 18–65 - NCT05168124Recruiting
Therapy or short breaks for chronic fatigue syndrome (CFS/ME)
This study tests whether Acceptance and Commitment Therapy (ACT) or doing brief “micro breaks” can improve symptoms in people with CFS/ME. It checks safety and whether you can follow the online program over the study period.
ZurichAges 18–55 - NCT06775262Recruiting
chronic fatigue in internal medicine patients
This study looks at people with chronic fatigue who saw a doctor but no physical cause was found. It aims to understand their experiences better.
Almere Stad, FlevolandAges 18 years+ - NCT03773003Recruiting
Study of fatigue caused by cancer or chronic fatigue
This study looks at why fatigue happens in people with cancer and, in some cases, in people with chronic fatigue conditions. It may help researchers better understand the causes of fatigue so future treatments can be improved.
Homburg, SaarlandAges 18–80 - NCT06830655Enrolling by invitation
Climbing performance and body factors study
This study looks at how mobility, balance, and fatigue affect climbing performance. If you are a healthy climber, you may help researchers understand what makes a better climber.
Gdansk, GdańskAges 15–45 - NCT07846618Recruiting
Mental fatigue and leg strength study
This study looks at how mental tiredness affects leg muscle strength. You will do some mental tasks and then leg exercises to see if your strength changes.
Pensacola, FloridaAges 18–39 - NCT07602933Recruiting
Light Therapy for Muscle Fatigue from Electrical Stimulation
This study tests whether light therapy can reduce muscle fatigue and damage caused by electrical muscle stimulation. Researchers want to see if this non-invasive light treatment helps muscles recover faster.
Porto Alegre, Rio Grande do SulAges 18–45 - NCT07491315Recruiting
Do ME/CFS patients react differently to exercise?
This study looks at whether people with ME/CFS have a different reaction to exercise compared to people with heart conditions who also feel tired. It involves filling out online questionnaires and may help doctors better understand ME/CFS.
MarseilleAges 18 years+ - NCT07405060Recruiting
How age and muscle fatigue affect balance and control
This study looks at how getting older and muscle tiredness change your ability to keep your balance and control your movements. It may help explain why some people are more likely to fall.
TaoyuanAges 20–85 - NCT07323810Recruiting
How mental fatigue affects running, tracked by sensors
This study uses special sensors to see how mental tiredness affects your running performance. If you're a healthy, experienced runner between 18 and 35, you would be asked to run while wearing monitors that track your body's signals.
BrusselsAges 18–35 - NCT07278388Recruiting
Fatigue and brain fog in long COVID: a brain study
This trial uses brain scans to understand why people with long COVID feel very tired or have trouble thinking clearly. It could help find new treatments for these symptoms.
Baltimore, MarylandAges 18–75 - NCT07231172Recruiting
Fatigue after stroke and its link to clinical factors
This study examines how fatigue affects people who have had a stroke, looking at physical and mental health factors. It may help understand why some people feel more tired than others after a stroke.
AnkaraAges 18 years+ - NCT07025863Enrolling by invitation
Reducing alarm fatigue in NICU nurses program
This study tests a program to help NICU nurses manage alarm fatigue (stress from constant monitors). It aims to improve well-being and job performance.
Guiyang, GuizhouAges Any age - NCT07014111Recruiting
Fight Fatigue: muscle relaxation and walking for dialysis patients
This study tests a simple program that combines muscle relaxation exercises and walking to help reduce fatigue in people with end-stage kidney disease who are on dialysis. You'll receive text messages to guide you and track your progress.
Chicago, IllinoisAges 18 years+ - NCT06710548Recruiting
REVITALIZE: Reducing Fatigue in Ovarian Cancer on PARP Inhibitors
This study tests whether a program called REVITALIZE can help reduce severe fatigue in women with ovarian cancer who are currently taking a PARP inhibitor (a type of targeted therapy). The goal is to see if this approach improves daily energy and quality of life.
Aurora, ColoradoAges 18 years+ - NCT06441617Enrolling by invitation
Online program to reduce fatigue in multiple sclerosis
This trial tests an online self-management program to help reduce fatigue in people with MS. You'll use a website or app over 24 weeks, and researchers will check how well it works.
Washington D.C., District of ColumbiaAges 22 years+ - NCT04041154Recruiting
Study of how the brain senses effort cost
This study asks people to do tasks while the researchers measure brain activity, to understand how the brain represents the “cost” of effort. It may help improve understanding of effort-related problems in mental and neurological conditions.
Baltimore, MarylandAges 18–35 - NCT07873424Recruiting
Recumbent cycling and electrical stimulation for leg rehab
This study tests whether combining recumbent cycling with electrical muscle stimulation can improve leg function. It may help people with leg weakness or injuries to recover strength and mobility.
Oro Verde, Entre Ríos ProvinceAges 18–60 - NCT04151693Recruiting
Group therapy for chronic fatigue syndrome
This trial tests a health-psychology–based rehabilitation program delivered in a group setting for people with chronic fatigue syndrome (ME/CFS). It may help by teaching strategies to cope with symptoms and improving daily functioning through structured group support.
LahtiAges 18–65 - NCT06363396Recruiting
Brain scan study for fatigue after stem cell transplant
This study uses a special brain scan (PET) to look at why people feel very tired or have trouble thinking clearly after a stem cell transplant. It aims to better understand these problems to help future patients.
StockholmAges 20–75 - NCT07816263Recruiting
Guaraná supplement for cancer-related fatigue
This trial tests whether a natural supplement called guaraná can help reduce fatigue in people undergoing cancer treatment. Guaraná contains caffeine and other compounds that may boost energy and improve well-being.
Bogotá, Bogota D.C.Ages 18 years+
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Fatigue trials by city
Studies with a site in or near these metro areas.
Fatigue trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for fatigue?
- Yes. Clin2 currently lists 293 recruiting fatigue studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a fatigue trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a fatigue trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.