Clinical trials
Fatigue clinical trials
Below are recruiting fatigue clinical trials, each written for real people, not researchers. We’re tracking 293 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07809776Recruiting
Tai chi for tiredness during radiation for head and neck cancer
This study tests whether practicing tai chi during radiation therapy helps reduce cancer-related tiredness (fatigue) in people with head and neck cancer. If you are undergoing radiation and feel tired, this gentle exercise may help you feel better.
Chengdu, SichuanAges 18–80 - NCT06505421Recruiting
Eccentric exercise for fatigue in multiple sclerosis
This study tests whether a specific type of leg exercise (called eccentric exercise) can help reduce fatigue in people with Multiple Sclerosis. It involves walking and other exercises to see if they improve how tired you feel.
New York, New YorkAges 18–75 - NCT07806682Recruiting
Low-intensity exercise for lung cancer fatigue relief
This trial tests whether a gentle, low-intensity endurance exercise program can improve energy levels, quality of life, and certain health measures in lung cancer patients who feel tired. It aims to help you feel better during and after cancer treatment.
TaipeiAges 20–70 - NCT07789106Recruiting
CoQ10 for fatigue and strength in GLP-1 users
This study tests whether Coenzyme Q10 (CoQ10) can help reduce fatigue and improve muscle strength in people who are taking GLP-1 medications for weight management. You will be asked to take a daily supplement (CoQ10 or placebo) for a period and track your progress via a smartphone app.
GlasgowAges 30–65 - NCT07753122Recruiting
Hydrogen water for chronic fatigue syndrome
This trial tests whether drinking hydrogen water can help with symptoms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). If you have ME/CFS, this study might show if hydrogen water is a helpful treatment.
Stony Brook, New YorkAges 18–65 - NCT05241405Recruiting
American ginseng to reduce fatigue after cancer treatment
This study tests whether taking American ginseng for 8 weeks can lessen long-lasting tiredness (fatigue) in people who recently finished certain breast or gynecologic cancer treatments. It may help reduce fatigue when other causes have been ruled out.
AmiensAges 18 years+ - NCT07707648RecruitingEarly Phase 1
Testing ENCER for fatigue during chemo or radiation
This trial tests if ENCER can safely help with cancer-related fatigue. You can join if you're starting a new round of chemo or radiation and can use a smartwatch and answer digital surveys.
Tel AvivAges 18 years+ - NCT06201026Recruiting
Reducing Fatigue in New MS With Individualized Training
This trial tests if a personalized home training program can help reduce severe fatigue in people with relapsing-remitting MS who were recently diagnosed. You'll use a phone app to do exercises designed for you, and researchers will check your energy levels over time.
Saint-EtienneAges 18–60 - NCT07669519RecruitingPhase 3
Supplement for fatigue in stage IV colon cancer
This study tests an oral supplement (Nuvastatic) to see if it helps reduce fatigue in people with stage IV colon cancer who are starting chemotherapy for the first time. If you are 18–65 and have fatigue that is affecting you, this trial might offer a way to feel better.
Srikakulam, Andhra PradeshAges 18–65 - NCT07669467RecruitingPhase 3
Nuvastatic for fatigue in triple-negative breast cancer patients
This trial tests whether Nuvastatic, a natural supplement, can help reduce fatigue in women with triple-negative breast cancer who are about to start chemotherapy. If you have stable or worsening fatigue and meet the other criteria, you may be able to join.
Visakhapatnam, Andhra PradeshAges 18–65 - NCT07665593Recruiting
AI breathing training after open heart surgery
This trial tests if an AI-assisted breathing exercise device can reduce pain, fatigue, and improve breathing in patients recovering from open heart surgery.
Kocaeli, İzmitAges 18 years+ - NCT07654946Recruiting
Taurine supplement and muscle endurance in healthy adults
This study tests whether taking a taurine supplement can help your muscles work longer before getting tired. Researchers will use a light sensor on your leg to see how muscles use oxygen.
Baton Rouge, LouisianaAges 18–40 - NCT07644611Recruiting
Sleep and Mental Fatigue Study for Students
This study looks at how sleep affects mental tiredness and ability to focus in college students. Researchers want to understand whether improving sleep could help students think more clearly and perform better academically.
Lugano, Canton TicinoAges 18 years+ - NCT07637084Recruiting
Light therapy for chronic pain and fatigue in Ehlers-Danlos Syndrome
This trial tests whether a non-invasive light therapy called photobiomodulation can reduce chronic pain and fatigue in people with hypermobile Ehlers-Danlos Syndrome (hEDS), a genetic condition affecting connective tissue. The light is applied to the skin and may help cells produce energy and reduce inflammation.
Boulogne-Billancourt, Île-de-France RegionAges 18 years+ - NCT07621068Recruiting
Hyperbaric Oxygen Therapy for Chronic Fatigue Syndrome
This study tests whether breathing pure oxygen in a pressurized chamber can reduce fatigue and improve symptoms in people with mild-to-moderate chronic fatigue syndrome (ME/CFS). The therapy may help your body recover better by increasing oxygen supply to affected tissues.
ZrifinAges 18 years+ - NCT06248229RecruitingPhase 4
Testing Dyanavel XR for fatigue in adults with ADHD
This trial tests whether the medication Dyanavel XR (a long-acting amphetamine) can help reduce fatigue in adults with ADHD. It is for people who have both ADHD and significant tiredness, and who are not currently taking stimulant ADHD drugs.
Rochester Hills, MichiganAges 18–65 - NCT07619209Recruiting
Relaxation exercises for cancer patients with breathing difficulty
This study tests whether gentle muscle relaxation and deep breathing exercises help cancer patients in palliative care feel less breathless, less tired, and better able to care for themselves. You would learn and practice these exercises and answer questions about how you feel.
Ankara, YENIMAHALLEAges 18 years+ - NCT07615478Recruiting
Hot spring therapy for reducing fatigue during altitude rowing training
This study tests whether soaking in hot springs can help young rowers feel less tired and recover better while training at high altitude. Researchers want to see if the hot water helps the body's natural fatigue-fighting systems work better.
Macao, MacaoAges 12–16 - NCT07582458RecruitingPhase 2/Phase 3
Modafinil for Fatigue in Controlled Inflammatory Bowel Disease
This trial tests whether modafinil (a wakefulness-promoting medication) can reduce severe fatigue in people with inflammatory bowel disease (IBD) whose disease is well-controlled. If you have persistent exhaustion despite your IBD being stable, this study may help determine if this medication works for you.
Arnhem, GelderlandAges 18–75 - NCT03609112Recruiting
Study brain and thinking risks in children with solid tumors
This study looks at how cancer treatment may affect children’s thinking and brain health. It may help doctors better understand risks so they can monitor and support learning and memory during and after treatment.
Villejuif, Val De MarneAges Any age - NCT07546539Recruiting
Light Therapy for Chronic Fatigue Syndrome
This study tests whether a special type of light therapy (called photobiomodulation) can reduce severe tiredness in people with chronic fatigue syndrome. The light is applied to the skin and may help boost energy levels and improve daily function.
Larkana, SindhAges 18–60 - NCT07547566Recruiting
TECAR Therapy vs. Cycling for Athletic Recovery
This study compares two recovery methods—TECAR therapy (a heating treatment) and cycling—to see which helps young athletes recover better after jumping exercises. The goal is to understand which approach reduces fatigue and helps athletes bounce back faster.
Córdoba, CórdobaAges 18 years+ - NCT07544394Recruiting
Understanding Fatigue in Sjögren's Syndrome
This study explores why people with Sjögren's syndrome experience fatigue and what factors predict it. Researchers will follow you for 3 months to better understand your fatigue patterns and potentially improve treatment.
KahramanmaraşAges 18 years+ - NCT07523113Recruiting
Brain Fog Treatment for ME/CFS Using Cognitive Training
This study tests whether a computerized cognitive training program combined with a mild electrical nerve stimulation device (worn on the ear) can help improve thinking and memory problems in people with ME/CFS. The goal is to see if this approach helps with brain fog and daily functioning.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for fatigue?
- Yes. Clin2 currently lists 293 recruiting fatigue studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a fatigue trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a fatigue trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.