Clinical trials
Fatigue clinical trials
Below are recruiting fatigue clinical trials, each written for real people, not researchers. We’re tracking 289 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06137833Recruiting
Micronutrient supplement for severe tiredness in breast cancer chemo
This study tests whether a specially designed vitamin and mineral supplement can help reduce severe tiredness in women while they are receiving chemotherapy for breast cancer. If you are currently in treatment and have bothersome fatigue, this trial may offer a way to feel better.
Brescia, BRESCIAAges 18 years+ - NCT06156176Recruiting
Exercise for COVID-19 fatigue: a feasibility study
This study tests whether a personalized exercise program can help reduce fatigue after a COVID-19 infection. You'll work with a coach over video calls to see if gentle activity can improve your energy levels.
London, OntarioAges 18 years+ - NCT06170645Recruiting
Vagus nerve stimulation for fatigue in fibromyalgia or long COVID
This trial tests whether a gentle electrical stimulation device on the ear (vagus nerve) can help reduce fatigue when combined with exercise. It is for people with fibromyalgia or long COVID who still feel exhausted after a rehab program.
Saint-EtienneAges 18 years+ - NCT06170970RecruitingPhase 2
Solriamfetol for fatigue in multiple sclerosis
This study tests whether solriamfetol, a medication that promotes wakefulness, can reduce fatigue in people with multiple sclerosis. If you struggle with tiredness and sleepiness, this trial may help you understand how this drug works for MS-related fatigue.
Baltimore, MarylandAges 18–60 - NCT06201026Recruiting
Reducing Fatigue in New MS With Individualized Training
This trial tests if a personalized home training program can help reduce severe fatigue in people with relapsing-remitting MS who were recently diagnosed. You'll use a phone app to do exercises designed for you, and researchers will check your energy levels over time.
Saint-EtienneAges 18–60 - NCT06217276Recruiting
Breathing muscle fatigue and leg oxygen in COPD
This study looks at how breathing muscle tiredness relates to oxygen levels in leg muscles for people with moderate-to-severe COPD. It may help patients understand their condition better.
Istanbul, ZeytinburnuAges 18–75 - NCT06248229RecruitingPhase 4
Testing Dyanavel XR for fatigue in adults with ADHD
This trial tests whether the medication Dyanavel XR (a long-acting amphetamine) can help reduce fatigue in adults with ADHD. It is for people who have both ADHD and significant tiredness, and who are not currently taking stimulant ADHD drugs.
Rochester Hills, MichiganAges 18–65 - NCT06286072Recruiting
Can education and reminders help with COPD fatigue?
This trial tests whether educational materials and text message reminders can help reduce fatigue in people with COPD who have been hospitalized for at least 3 days. It aims to see if these simple tools can improve how you feel day to day.
Kırşehir, CenterAges 18–85 - NCT06363396Recruiting
Brain scan study for fatigue after stem cell transplant
This study uses a special brain scan (PET) to look at why people feel very tired or have trouble thinking clearly after a stem cell transplant. It aims to better understand these problems to help future patients.
StockholmAges 20–75 - NCT06480539RecruitingPhase 4
Dexmedetomidine for Better Sleep After Lung Surgery in Older Adults
This study tests whether giving a medicine called dexmedetomidine at night can help older adults sleep better and feel less tired after lung surgery. If you are 60 or older and having lung surgery through small cuts (thoracoscopy), you may be able to join.
Genk, LimburgAges 60 years+ - NCT06482515RecruitingPhase 2
Meal timing for fatigue after blood cancer treatment
This study tests whether timing your meals in a certain way can help reduce fatigue in people who have finished treatment for a blood cancer. If you're still struggling with tiredness, this may offer a practical, non-drug approach to feel better.
Baltimore, MarylandAges 18 years+ - NCT06505421Recruiting
Eccentric exercise for fatigue in multiple sclerosis
This study tests whether a specific type of leg exercise (called eccentric exercise) can help reduce fatigue in people with Multiple Sclerosis. It involves walking and other exercises to see if they improve how tired you feel.
New York, New YorkAges 18–75 - NCT06505590Recruiting
Online support for cancer-related fatigue
This trial tests an online support program designed to help people with cancer manage fatigue. If you have had moderate to severe fatigue for at least a week, you may be able to join from home.
VillejuifAges 18 years+ - NCT06511050RecruitingPhase 1/Phase 2
Testing Lumbrokinase for Long COVID, Lyme, and Chronic Fatigue
This trial tests a supplement called Lumbrokinase (derived from earthworms) to see if it helps reduce symptoms in people with Long COVID, post-treatment Lyme disease syndrome, or ME/CFS. It may benefit those whose daily life is significantly affected by these conditions.
New York, New YorkAges 18 years+ - NCT06569550Recruiting
Fatigue treatment study for multiple sclerosis
This trial tests a brain stimulation therapy designed to reduce fatigue in people with multiple sclerosis. If you experience moderate to severe fatigue and have a stable medication routine, this study might help determine if a non-invasive treatment can improve your energy levels.
Hvidovre, Capital RegionAges 18–65 - NCT06666452Recruiting
Combined fatigue program for arthritis patients
This trial tests a combined program to help reduce severe fatigue in people with rheumatoid arthritis, psoriatic arthritis, or spondyloarthritis. You must have had significant fatigue for at least 3 months and be in a stable phase of your disease.
Sønderborg, DenmarkAges 18 years+ - NCT06819254RecruitingPhase 4
Fisetin for fatigue in older cancer survivors
This study tests whether a natural compound called fisetin can reduce fatigue in people aged 60+ who have completed cancer treatment. If you still feel tired often, this pill-based treatment might help you regain energy.
Winston-Salem, North CarolinaAges 65 years+ - NCT06830018Recruiting
New megestrol for advanced stomach or colon cancer with fatigue
This study tests a new form of megestrol (a medicine that can boost appetite and energy) for people with advanced stomach or colorectal cancer who also have fatigue and poor appetite. It is given as a first treatment, meaning you haven't had chemotherapy yet for your advanced cancer.
Shenyang, LiaoningAges 18–75 - NCT06846177Recruiting
Training programs for fatigue after stroke
This study compares two types of training—graded activity and task-oriented training—to see which one helps reduce fatigue after a stroke. If you are between 40 and 60 years old, had a stroke over 4 months ago, and often feel very tired, you may be able to join.
Mansehra, KPKAges 40–60 - NCT06905587RecruitingPhase 3
Methylphenidate for fatigue in young brain tumor survivors
This trial tests whether the medicine methylphenidate (often used for ADHD) can help reduce severe fatigue in children and teens who have finished treatment for a brain tumor. If you're a young brain tumor survivor struggling with ongoing tiredness, this study may offer a new option.
AalborgAges 6–27 - NCT06952413RecruitingPhase 2
Rituximab for chronic fatigue syndrome (ME/CFS) trial
This trial tests if rituximab, a drug that affects the immune system, can help people with ME/CFS. You'll receive the drug in the hospital and be monitored for safety and improvement.
Kodaira, TokyoAges 18–65 - NCT06960720Recruiting
Weight lifting program for breast cancer fatigue
This trial tests whether a 3-month resistance exercise program (like lifting weights) can help reduce fatigue in women who have had breast cancer. You may be eligible if you were diagnosed with non-metastatic breast cancer 1-3 years ago and feel tired, even if only a little.
Morgantown, West VirginiaAges 18 years+ - NCT06980636RecruitingPhase 4
Shengmai liquid for long covid fatigue trial
This trial tests if a traditional Chinese medicine, Shengmai Liquid, can help reduce fatigue in people with long COVID. It is for adults aged 18 to 75 who feel tired for a long time after a COVID infection.
Beijing, ChinaAges 18–75 - NCT07001241RecruitingPhase 2
Telehealth exercise for fatigue in rural cancer survivors
This study tests a 12-week home exercise program delivered via video calls, designed to help reduce fatigue and improve physical function in people who have finished treatment for breast or prostate cancer and live in rural areas.
Aurora, ColoradoAges 18–89
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Common questions
- Are there clinical trials for fatigue?
- Yes. Clin2 currently lists 289 recruiting fatigue studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a fatigue trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a fatigue trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.