Clinical trials
Fibrosis clinical trials
Below are recruiting fibrosis clinical trials, each written for real people, not researchers. We’re tracking 417 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07289100Recruiting
Smart home monitoring for lung flare-ups in CF and bronchiectasis
This trial tests if a smart home monitoring system (using sensors and AI) can detect sudden lung flare-ups early in people with cystic fibrosis or bronchiectasis. It may help you get treatment sooner when you are admitted to the hospital for IV antibiotics.
Cambridge, CambridgeshireAges 18 years+ - NCT07296081Recruiting
PET scan study for heart scarring in heart failure
This study uses a special PET scan to look for scarring (fibrosis) in the heart muscle of people with heart failure. It may help doctors better understand why some hearts get stiff or weak.
Coimbra, Coimbra DistrictAges 18 years+ - NCT07284602RecruitingPhase 3
Comparing a new drug to pirfenidone for lung scarring
This trial tests a new medicine, LYT-100 (deupirfenidone), against the standard drug pirfenidone for people with idiopathic pulmonary fibrosis (IPF). It aims to see if the new drug works better or has fewer side effects.
Palm Spring, CaliforniaAges 40 years+ - NCT05644717RecruitingPhase 4
Testing erugliflozin for fatty liver and diabetes control
This trial studies whether erugliflozin can reduce liver fat and liver scarring (fibrosis) while also improving blood sugar in people with type 2 diabetes and fatty liver disease (NASH/NAFLD). It’s designed for people who haven’t used certain diabetes medicines like SGLT2 inhibitors or insulin before.
Peshawar, KPKAges 18–65 - NCT07275905RecruitingPhase 1
Phage therapy for chronic achromobacter lung infection in cystic fibrosis
This study tests whether giving you a mixture of viruses (called phages) that specifically target the bacteria Achromobacter can help treat your chronic lung infection. You would breathe in the phages, and the study will check if this is safe and helps improve your breathing.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07269262Recruiting
Support program for PPF patients and their caregivers
This study tests a support program for people with progressive pulmonary fibrosis and their caregivers. It focuses on helping both the patient and the person who helps care for them.
Charleston, South CarolinaAges 18 years+ - NCT07271576Recruiting
Phycocyanin study for liver fibrosis and cirrhosis
This trial tests if phycocyanin (a natural blue pigment from spirulina) can help protect the liver and slow damage from fibrosis or cirrhosis. It may be an option if you have stable liver disease and are looking for supportive therapy.
HangzhouAges 18–75 - NCT03478553Recruiting
Study of genes in people with pulmonary fibrosis
This study looks at genetic (inherited) factors related to pulmonary fibrosis, especially idiopathic pulmonary fibrosis (IPF). It may help researchers understand why some families are more affected and could guide future testing or treatments.
Aurora, ColoradoAges 18 years+ - NCT06528418Recruiting
Breath test to find lung diseases
This study uses a simple breath test to detect different lung diseases. By analyzing the chemicals in your breath, researchers hope to find a faster, non-invasive way to diagnose lung conditions. It may be an option if you have a known lung disease and have a recent CT scan.
Guangzhou, GuangdongAges 18–100 - NCT07251725Recruiting
Genetic study of family-linked lung scarring
This study looks for genetic causes of pulmonary fibrosis that runs in families. You and your affected family member(s) would provide blood samples and health info to help researchers understand why lung scarring happens.
Pavia, LombardyAges 18 years+ - NCT07236541Recruiting
Mucus plugs and lung scarring in COPD patients having lung cancer surgery
This study looks at whether mucus plugs (thick mucus blocking the airways) in people with COPD might lead to more lung scarring after lung cancer surgery. It compares lung tissue from people with COPD to those with normal lungs.
ShanghaiAges 18–89 - NCT06909409Recruiting
Vitamin D and lung immune cells in lung fibrosis
This study looks at how vitamin D affects immune cells in the lungs of people with a lung scarring condition called idiopathic pulmonary fibrosis (IPF) or other similar lung diseases. It tests if vitamin D levels are linked to how these cells work.
Aarhus NAges 18 years+ - NCT06122233Recruiting
Digital self-management for fibrotic lung disease
This trial tests whether a digital self-management program (using a smartphone or tablet) helps people with fibrotic interstitial lung disease better manage their symptoms and quality of life. If you have this lung condition and can use a mobile device, this study could offer you extra support at home.
Sydney, New South WalesAges 18 years+ - NCT07230288RecruitingPhase 2
Study of ABBV-142 for Idiopathic Pulmonary Fibrosis
This trial is testing a new antibody drug, ABBV-142, to see if it can reduce disease activity in adults with idiopathic pulmonary fibrosis (IPF). It may help if your IPF was diagnosed within the last 7 years and you meet certain health criteria.
Birmingham, AlabamaAges 40 years+ - NCT06915961Recruiting
HE4 Protein and Lung Function in Cystic Fibrosis
This study looks at a protein in the blood (HE4) and how it relates to lung function in children with cystic fibrosis. It also tests a quality improvement plan to help manage CF. The goal is to find better ways to track and treat the disease.
Cairo, AbbasiaAges 6 years+ - NCT06917196Recruiting
Inhaled imatinib for advanced lung disease before or after transplant
This trial tests whether a special inhaled form of the medicine imatinib can help people with advanced lung scarring or high blood pressure in the lungs. It is designed for those who are on the path to a lung transplant or already received one.
Pavia, PaviaAges 18 years+ - NCT07201922RecruitingPhase 3
Can a new pill help slow lung changes in people with family risk?
This trial tests a new drug called nerandomilast to see if it can slow down early lung changes in people who have a close family member with a type of lung scarring called pulmonary fibrosis. You may join if you are 40 or older, have a parent, sibling, or child with this condition, and have early signs of lung changes on a CT scan.
Los Angeles, CaliforniaAges 40 years+ - NCT07201363Recruiting
Inflammation and scarring markers after TAVI
This study looks at markers of inflammation and scarring in people who develop heart rhythm problems after having a TAVI procedure (a minimally invasive valve replacement). It may help doctors understand and predict these complications.
Rijeka, CroatiaAges 18 years+ - NCT05098717Recruiting
PEEP settings guided by lung pressure in pulmonary fibrosis
This trial tests whether using lung-pressure measurements to adjust ventilator PEEP (a breathing-support setting that keeps airways open) can help people with pulmonary fibrosis who are on a breathing machine for acute respiratory failure. It may improve breathing comfort and oxygenation by finding the best PEEP level for you.
ModenaAges 18–90 - NCT07192679Recruiting
MAGNIFY Study: New MRI for cystic fibrosis lung health
This study tests a new type of MRI scan that uses either special gas (xenon) or regular MRI to take detailed pictures of the lungs in people with cystic fibrosis. The goal is to see how well these scans can track lung health over time, without using X-ray radiation.
SheffieldAges 1 year+ - NCT06364176RecruitingPhase 2
Adding losartan to improve Trikafta response in CF
This study tests whether adding the blood pressure medication losartan can help the standard CF drug Trikafta work better by reducing inflammation. It's for people with CF who still have high sweat chloride levels despite taking Trikafta.
Kansas City, KansasAges 12 years+ - NCT06561529Recruiting
Stomach bypass stent for liver scarring in obese patients
This study tests a stomach bypass stent to treat liver scarring caused by fatty liver disease in people with obesity. If you have obesity and a confirmed liver condition called NASH with moderate scarring, this stent might help you achieve weight loss and improve your liver health.
Riga, RigaAges 18–65 - NCT07121413RecruitingPhase 2
Testing SV001 for Idiopathic Pulmonary Fibrosis
This trial tests a new drug called SV001 to see if it is safe and tolerable for people with idiopathic pulmonary fibrosis (IPF). If you have IPF and meet certain health criteria, this study may help find new treatment options.
ChengduAges 40 years+ - NCT07102043Enrolling by invitation
Glucose study in cystic fibrosis related diabetes
This study looks at how the body handles sugar in people with cystic fibrosis related diabetes. Researchers want to learn more about glucose metabolism to improve care for people with CFRD.
Birmingham, AlabamaAges 21–75
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Common questions
- Are there clinical trials for fibrosis?
- Yes. Clin2 currently lists 417 recruiting fibrosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a fibrosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a fibrosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.