Clinical trials
Frailty at Older Adults clinical trials
Below are recruiting frailty at older adults clinical trials, each written for real people, not researchers. We’re tracking 67 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05307666Enrolling by invitationPhase 4
Older adults using many medications may get simpler care
This study looks at whether older adults do better when their medication plan is simplified. You may be able to join if you’re at least 80, live in the community, and take 6 or more regular oral medications.
Edmonton, AlbertaAges 80 years+ - NCT07345832Recruiting
Volunteer-led lifestyle program for older adults with muscle loss
This study tests a volunteer-led program to improve muscle health in older adults with sarcopenia. It uses a mobile app to guide exercise and nutrition, and aims to see if this approach helps people regain strength.
Hong KongAges 60 years+ - NCT07237334Recruiting
Emergency care study for older adults (GEM-U)
This study tracks health outcomes for older adults who are cared for in a special emergency unit designed for their needs. It helps researchers learn what works best for seniors who come to the emergency room with medical problems.
Limerick, MunsterAges 75 years+ - NCT07643064Recruiting
Exercise and health checks for frail older adults
This study tests whether a combination of tailored exercise classes and comprehensive health assessments can improve strength, function, and overall well-being in older adults who are frail or at risk of becoming frail. You would attend supervised exercise sessions and receive personalized health evaluations at a primary care center.
Tacoronte, Santa Cruz de TenerifeAges 70 years+ - NCT07282561Recruiting
Nutrition and virtual rehab for older adults with shoulder issues
This study tests whether a virtual reality shoulder exercise program combined with nutritional support helps older adults recover better after surgery. It focuses on people who are frail and have shoulder problems needing surgery.
Rome, RomeAges 60 years+ - NCT07346989Recruiting
Brain stimulation to improve function in frail older adults
This study uses a gentle, non-invasive brain stimulation technique (called transcranial direct current stimulation, or tDCS) to see if it can improve physical function and daily activities in older adults who are showing early signs of frailty. You will be asked to do some simple exercises and cognitive tasks while receiving or not receiving the stimulation.
Valencia, ValenciaAges 65–90 - NCT05994482Recruiting
Surveillance colonoscopy study in older veterans
This study looks at how often older veterans (age 75 and older) should get a follow-up colonoscopy after having polyps removed. Researchers will review medical records and talk to patients and doctors to help create better guidelines for surveillance colonoscopies in older adults.
San Diego, CaliforniaAges 75 years+ - NCT06190288Recruiting
Transitional care for frail older adults leaving the hospital
This study tests a program where a team of healthcare workers helps frail older adults transition from the hospital back home. It aims to prevent health problems and support you in managing your health after discharge.
BaselAges 65 years+ - NCT06248723Recruiting
Preventing memory decline in older adults with lifestyle changes
This study tests a personalized program of lifestyle changes (diet, exercise, brain training, etc.) to see if it can prevent memory loss and keep older adults independent. You may qualify if you are 60+, have mild frailty, and have certain risk factors for dementia.
MonzaAges 60 years+ - NCT06731413RecruitingPhase 2
Mild chemo with immunotherapy for older adults with advanced lung cancer
This study tests a milder chemotherapy combined with an immunotherapy drug (anti-PD-1) as the first treatment for advanced lung cancer in older or frailer adults. It aims to see if this approach works better with fewer side effects.
Richmond, VirginiaAges 18 years+ - NCT07351877Recruiting
Vibration therapy for strength and movement in older adults and stroke survivors
This study tests if a precise vibration device can improve muscle function and mobility in older adults with frailty and stroke survivors. It may help reduce knee pain and enhance rehabilitation outcomes.
TaipeiAges 18–95 - NCT07359105Recruiting
Statin vs. LDL Goal Therapy for Older Adults with Diabetes
This trial compares two approaches to lower cholesterol in people aged 70+ with type 2 diabetes: a moderate statin dose versus adjusting treatment to reach a personalized LDL-C target. It aims to find which strategy better prevents heart problems.
SeoulAges 70 years+ - NCT07388173Recruiting
How respiratory infections affect daily life in older adults
This study looks at how acute respiratory infections (like the flu, COVID-19, or RSV) affect older adults' daily functioning. If you are 60+ and in the hospital with one of these viruses, your participation would help doctors understand the lasting impact on independence and health.
Rochester, New YorkAges 60 years+ - NCT07400692Recruiting
Surgery vs. Non-surgery for Broken Elbow in Older Adults
This study compares two ways to treat a certain type of broken elbow in adults over 65 who are not extremely active or frail. It tests if using a metal plate to fix the bone during surgery leads to better arm function and recovery than treating the injury without surgery.
LuganoAges 65 years+ - NCT07408882Recruiting
Home care program for people needing extra support
This study tests whether a home care program helps people who need daily assistance or have complex health needs. It aims to see if this integrated support can improve well-being and reduce hospital visits.
Barcelona, BarcelonaAges 70 years+ - NCT07074639Recruiting
Brain and body training with video games for frail older adults
This trial tests a fun home-based video game program that combines thinking exercises with physical movements to help older adults who are frail. The goal is to see if this training can improve physical and mental function.
ZurichAges 50 years+ - NCT07348081Recruiting
Digital support program for caregivers of ER patients
This trial tests a digital program that helps caregivers coordinate and monitor care for adults leaving the emergency department. It may reduce stress and make caring easier.
ParisAges 18 years+ - NCT06617806Recruiting
Preventing falls in very old, active adults
This trial tests if advanced practice nurses can help prevent falls in robust adults aged 80 and older. It may help you stay independent and avoid injuries.
Nantes, Loire-AtlantiqueAges 80 years+ - NCT06025240Recruiting
Better antibody monitoring after kidney transplant
This study tests a new way to monitor harmful antibodies after a kidney transplant. It may help prevent transplant rejection over time.
Liverpool, MerseysideAges 18 years+
Hear when a new Frailty at Older Adults trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for frailty at older adults?
- Yes. Clin2 currently lists 67 recruiting frailty at older adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frailty at older adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frailty at older adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.