Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,577 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05638464Recruiting
Brain stimulation to help hand movement after stroke
This trial studies whether a noninvasive brain stimulation technique can improve hand and arm function in people whose stroke happened more than 12 months ago. It may help if you have mild-to-moderate hand weakness and can follow training instructions.
Hong KongAges 18 years+ - NCT05655325Recruiting
Exercise program to improve thinking in older adults with mild memory trouble
This study tests whether a supervised exercise plan can improve executive thinking (like planning and task control) in older adults with mild cognitive impairment. Researchers also look for brain changes using an MRI.
New York, New YorkAges 55 years+ - NCT05659589Recruiting
Using a kidney toxin level to predict heart effects in AKI
This study looks at whether measuring indoxyl sulfate, a substance that can build up when kidneys are injured, can help predict how blood vessels and the heart are affected during acute kidney injury (AKI). It may help doctors understand who is at higher risk of heart-related problems while AKI is happening.
AmiensAges 18 years+ - NCT05662189Recruiting
PET scan study of beta cell function in diabetes
This study uses a special PET scan to measure how well insulin-producing cells (“beta cells”) in the pancreas are working in people with diabetes. It’s meant to help researchers understand diabetes biology and test whether the scan can reflect beta cell function.
Parma, PrAges 18–75 - NCT05664412Recruiting
Brain stimulation trial to improve thinking in 22q11.2 deletion
This trial tests a non-invasive brain stimulation approach to help improve executive function—skills like planning, attention, and self-control—in people with 22q11.2 deletion syndrome. If you qualify, you would be asked to participate and allow study procedures to see whether this treatment helps.
Geneva, Canton of GenevaAges 14–25 - NCT05670288Recruiting
Studying how gut bacteria affect digestion after spinal cord injury
This study looks at how changes in gut bacteria may affect bowel function and metabolism during the first year after a spinal cord injury. You may be asked about bowel symptoms and other factors, and your results may help guide future care for digestion problems after injury.
Birmingham, AlabamaAges 18–85 - NCT05671198Recruiting
Ultrasound test of breathing muscle function in severe COPD flare
This trial studies how well your diaphragm (the main breathing muscle) works during a severe COPD flare, using an ultrasound scan. It may help doctors better assess breathing muscle performance when COPD symptoms suddenly worsen.
Zwolle, OverijsselAges 18 years+ - NCT05674617Recruiting
PTSD treatment for Veterans with serious mental illness
This trial tests a PTSD treatment approach for Veterans who also have a serious mental illness, aiming to improve day-to-day functioning. It includes Veterans who receive outpatient mental health care through the VA and have confirmed PTSD in the last month.
Baltimore, MarylandAges 18 years+ - NCT05674786Recruiting
Implant to help adults with severe balance nerve loss
This study tests whether a vestibular (balance) implant can improve balance and eye-stabilizing reflexes in adults with severe loss of balance function in both inner ears. You may benefit if long-term balance therapy has not helped enough.
Baltimore, MarylandAges 22–90 - NCT05676944Recruiting
Cochlear-like implant to help balance in older adults
This study tests a surgically placed implant aimed at improving balance and eye-stabilizing reflexes in older adults who have long-lasting, hard-to-treat inner-ear balance problems. You may be able to help researchers learn whether the device plus training can reduce dizziness and improve movement stability.
Baltimore, MarylandAges 65–90 - NCT05677022Recruiting
Posture and movement check during adapted exercise after breast cancer
This study looks at how a posture and movement assessment can help guide a tailored exercise program for people treated for non-metastatic breast cancer. It may help ensure the exercise is safer and more suited to your recovery needs.
MarseilleAges 18 years+ - NCT05681936Recruiting
Brain and spine scans after spinal cord injury or related conditions
This study uses brain and spine scans (and possibly nerve stimulation in some cases) to understand how the nervous system changes after spinal cord injury or certain spinal conditions. It may help researchers better track recovery and understand which changes are linked to symptoms like bladder problems.
ZurichAges 18 years+ - NCT05682924Recruiting
Study blood vessel function in CML patients on bosutinib
This study looks at how well your blood vessels work (“vasoregulation”) in people with chronic myeloid leukemia (CML) while taking bosutinib. The goal is to understand vascular changes and how they relate to treatment in CML.
MoscowAges 40–60 - NCT05684094Recruiting
Study links sleep, stress, and brain reward in risky drinking
This study looks at how sleep timing and stress affect brain responses related to reward and stress in young adults who drink heavily. It may help researchers understand why some people take bigger alcohol risks and how sleep and stress could be part of safer treatment.
Eugene, OregonAges 18–24 - NCT05701852Recruiting
Study brain scans during tasks in chronic nerve pain
This study looks at how brain activity changes in people with long-lasting nerve pain using an MRI scan while you do simple behavioral tasks. It may help researchers understand brain function in chronic neuropathic pain and how it affects day-to-day abilities.
ParisAges 18 years+ - NCT05701982Recruiting
Walking plus Tai Chi coach via video for COPD and pain
This study tests whether a phone/computer program that combines walking training with Tai Chi improves physical function (how well you move) in people who have COPD and long-term body or muscle pain. It may help you build strength, balance, and safer movement—especially if pain makes activity hard.
Boston, MassachusettsAges 40–100 - NCT05702931RecruitingPhase 4
Semaglutide for high blood sugar after kidney transplant
This trial tests semaglutide, a medicine that helps lower blood sugar, in people who develop high blood sugar shortly after a kidney transplant. It may help control blood sugar without harming the transplanted kidney, while also checking safety in this specific group.
CopenhagenAges 18–80 - NCT05708885Recruiting
Testing a tool to change esophagus muscle movement
This study looks at how a device affects how the esophagus muscles squeeze and relax. It may help people better understand swallowing problems, even if their usual esophagus test looks normal.
Milwaukee, WisconsinAges 18–90 - NCT05715814RecruitingPhase 3
Test diabetes-pill type medicine on kidney dialysis safety
This Phase 3 trial studies the safety of an SGLT2 inhibitor (a diabetes medication that can affect kidney fluid handling) in people on peritoneal dialysis. The goal is to see how the treatment works in your type of dialysis and whether it causes any problems.
Toronto, OntarioAges 18 years+ - NCT05721911Recruiting
Study using brain-cell tests to better understand Parkinson’s risk
This study collects blood and related samples to create a “biobank” and uses lab tests to study genetic risk in Parkinson’s disease and idiopathic REM sleep behavior disorder (RBD). It may help researchers understand why symptoms develop and improve future prevention or treatment approaches.
Milan, ItalyAges 18 years+ - NCT05723679Recruiting
Breathing-targeted program to improve function in HFpEF
This trial studies a breathing-focused treatment to help people with HFpEF (a type of heart failure) feel and function better. It may help improve daily activity by addressing breathing limits that commonly come with this condition.
Dallas, TexasAges 55–90 - NCT05733091Recruiting
Study of symptoms and function after certain head and neck cancers
This study looks at how symptoms and everyday functioning change for people with cancers of the nose/sinuses, the throat behind the nose (nasopharynx), or nearby skull-base areas. It may help doctors understand what survivors experience and improve long-term care.
Houston, TexasAges 18 years+ - NCT05748717Recruiting
Tests blood flow in children with sickle cell
This study measures how well blood flows through brain arteries in children with sickle cell disease using a noninvasive ultrasound test. It may help doctors better understand stroke risk and how treatments like hydroxyurea or recent care affect blood flow.
Kingston, Saint Andrew ParishAges 4–16 - NCT05752396Recruiting
Study of Pain Patterns Over Time in Kids
This study follows kids who have a specific type of chronic pain (headaches, stomach pain, or muscle/joint pain) to better understand how pain changes over time. It also checks whether certain factors are linked to those pain patterns.
Cincinnati, OhioAges 10–19
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,577 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.