Clinical trials
Gastric Cancer or Gastroesophageal Junction Adenocarcinoma clinical trials
Below are recruiting gastric cancer or gastroesophageal junction adenocarcinoma clinical trials, each written for real people, not researchers. We’re tracking 1,155 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05494086Recruiting
Laparoscopic stomach surgery for early gastric cancer
This study looks at a surgical technique (“dual-port laparoscopic distal gastrectomy”) for people with stomach adenocarcinoma at an early, specific stage. The goal is to remove the tumor with clean margins (called an “R0” result) and see how this approach works safely.
Guangzhou, GuangdongAges 18–75 - NCT05536102RecruitingPhase 2
Surgery-plus chemo and immunotherapy for HER2-negative gastric cancer
This Phase 2 trial studies whether adding two medicines (XELOX and tislelizumab) and another chemotherapy drug (PLD) around the time of surgery works better and is safe for people with stage III gastric (stomach) cancer. It is designed for tumors that are HER2-negative and PD-1/L1 positive.
ShanghaiAges 18–75 - NCT05537129Recruiting
Laparoscopic vs open stomach surgery for stomach cancer
This trial compares two ways surgeons remove the entire stomach (total gastrectomy): laparoscopic (small keyhole cuts) versus open surgery (one larger cut). It’s testing which approach is safer and works better for people with certain stages of stomach cancer.
Shanghai, Shanghai MunicipalityAges 20–80 - NCT05618821RecruitingPhase 2
Indocyanine green dye during stomach surgery for leftover cancer
This Phase 2 study tests whether using a special light-activated dye (indocyanine green) during laparoscopic stomach surgery can improve surgical outcomes for people with remnant (leftover) stomach cancer that has not spread to distant organs. It may help surgeons better find lymph nodes while operating.
Fuzhou, FujianAges 18–75 - NCT05722275Recruiting
Predicting peritoneal spread in advanced stomach cancer
This trial uses CT scan images and a look inside the abdomen (laparoscopy) to predict whether advanced stomach cancer has spread to the lining of the abdomen (the peritoneum). It may help your care team better identify who already has peritoneal spread and who might not.
BeijingAges 18 years+ - NCT05975749RecruitingPhase 2
Trastuzumab, serplulimab, and chemo after stomach cancer surgery
This Phase 2 study looks at whether adding serplulimab to trastuzumab and chemotherapy after surgery can lower the chance of stomach cancer coming back. It is for people with HER2-positive stage II–III stomach adenocarcinoma who have already had curative surgery with lymph node removal.
Shanghai, Shanghai MunicipalityAges 20–80 - NCT06008925RecruitingPhase 1/Phase 2
VG161 plus nivolumab for advanced gastric cancer
This trial tests a new combination therapy (VG161, a herpes-based virus therapy, plus nivolumab) for people with advanced stomach or gastroesophageal junction cancer that has not responded to at least two previous treatments, including a PD-1 inhibitor. The goal is to see if this combination can shrink tumors or slow cancer growth.
Beijing, Beijing MunicipalityAges 18–75 - NCT06027242Recruiting
Glutamine supplement after stomach cancer surgery
This trial tests if taking glutamine (a nutrient) as an oral supplement helps patients recover after surgery to remove stomach cancer. It aims to see if it improves healing and quality of life.
TaipeiAges 20 years+ - NCT06035250Recruiting
AI predicts stomach cancer response to chemo before surgery
This study tests whether an AI tool can predict how well stomach cancer responds to chemotherapy before surgery. It uses CT scans and biopsy images taken before treatment starts to see if the AI can help guide future care.
BeijingAges 18 years+ - NCT06036745RecruitingPhase 2
Palizumab and SOX chemo after gastric cancer surgery
This trial tests adding palizumab (an immunotherapy) to standard SOX chemotherapy after surgery for stage IIIB-IIIC gastric or GEJ cancer. It's for people whose tumors have certain markers (MSI-H, TMB-H, or high PD-L1) that may make immunotherapy more effective.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06055387Recruiting
Frailty care for older stomach cancer patients after surgery
This study tests a frailty assessment and intervention program for people aged 65+ with stage II or III stomach cancer who will have surgery and chemotherapy afterward. It aims to improve recovery and quality of life.
Taoyuan, TaiwanAges 65 years+ - NCT06054906RecruitingPhase 2
Immunotherapy plus chemo before surgery for stomach cancer
This trial tests a combination of an immunotherapy drug (sintilimab) and a low-dose weekly chemotherapy regimen before surgery for locally advanced stomach cancer that can be removed. The goal is to see if this approach helps shrink the tumor and improve outcomes.
ShanghaiAges 18 years+ - NCT06105515Recruiting
Keyhole and scope combo rescue for advanced stomach cancer
This trial tests a combined laparoscopy and endoscopy procedure as a rescue treatment for advanced stomach cancer. It is for patients who have a tumor that hasn't spread to other parts but cannot have standard stomach removal surgery.
StockholmAges 18 years+ - NCT06128252Recruiting
Taurine with chemotherapy and immunotherapy for gastric cancer
This trial tests whether adding taurine to standard chemo-immunotherapy before surgery helps treat locally advanced gastric cancer. It may be an option for patients whose tumors are PD-L1 positive and can be fully removed with surgery.
Wuhan, HubeiAges 18–75 - NCT06161207RecruitingPhase 3
Laparoscopic surgery for stomach cancer using 3D and dye
This trial tests a new way to remove stomach cancer using 3D-4K cameras and a special dye during laparoscopic (keyhole) surgery. It may help surgeons see the cancer better and remove it more precisely.
Fuzhou, FujianAges 18–75 - NCT06202105Recruiting
Laparoscopic vs open total gastrectomy for advanced stomach cancer
This trial compares two types of surgery for stomach cancer that has grown into deeper layers but has not spread to distant organs. The goal is to see if a keyhole (laparoscopic) approach is as safe and effective as traditional open surgery.
Bien Hoa, Dong NaiAges 18–80 - NCT06232395Recruiting
Early detection and monitoring of stomach cancer
This study is looking for people with stomach discomfort who are coming to this hospital for an endoscopy. Researchers will use the test results to help catch stomach cancer early and keep an eye on it after surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06253611RecruitingPhase 2
Probiotic plus immunotherapy and chemo for stomach cancer
This trial tests a new combination for advanced stomach cancer: an experimental probiotic (EXL01) plus standard immunotherapy (nivolumab) and chemotherapy (FOLFOX). It is for people whose tumors have a high PD-L1 marker and who have not received prior treatment for advanced disease.
AngersAges 18 years+ - NCT06296706RecruitingPhase 3
Study of a new docetaxel for advanced stomach cancer
This trial is testing a new form of the chemotherapy drug docetaxel (called albumin-bound docetaxel) for people with advanced stomach or gastroesophageal junction cancer that has worsened after initial treatment. It aims to see if this version of the drug works better or has fewer side effects.
Shijiazhuang, HebeiAges 18–75 - NCT06308510Recruiting
Improving stomach cancer detection with a fluid test
This study tests whether looking for certain DNA changes in the fluid from your belly can help doctors find stomach cancer that has spread. The goal is to make standard tests more accurate so treatment can be better planned.
RotterdamAges 18 years+ - NCT06313567RecruitingPhase 3
Metronomic capecitabine for stage III stomach cancer
This trial tests a low-dose, frequent regimen of the chemotherapy drug capecitabine (taken as a pill) to see if it can help prevent stage III stomach cancer from coming back after surgery. It's for people who have had their stomach cancer completely removed with a specific type of lymph node dissection.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06341595RecruitingPhase 2
Chemo, radiation and immunotherapy before surgery for stomach cancer with PALM
This trial tests combining chemotherapy, radiation, and an immunotherapy drug (sintilimab) before surgery for advanced stomach cancer that has spread to lymph nodes near the aorta (called PALM). The goal is to see if this approach can shrink the tumor enough to allow complete removal.
Nanjing, JiangsuAges 18–75 - NCT06395935Recruiting
Wellness care study for gastric cancer survivors
This study tests a wellness program for people who had surgery for gastric cancer (stomach cancer). It aims to help survivors recover better after their operation.
Changwon, Gyeongsandnam-doAges 19–75 - NCT06405113RecruitingPhase 2
Fecal transplant, chemo, and immunotherapy for advanced stomach cancer
This trial tests a combination of fecal microbiota transplant (FMT), chemotherapy (SOX), and an immunotherapy drug (Sintilimab) as a first treatment for advanced stomach or gastroesophageal junction cancer that cannot be removed by surgery. The goal is to see if this combination can shrink tumors and improve outcomes.
ChangzhouAges 18–80
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Common questions
- Are there clinical trials for gastric cancer or gastroesophageal junction adenocarcinoma?
- Yes. Clin2 currently lists 1,155 recruiting gastric cancer or gastroesophageal junction adenocarcinoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastric cancer or gastroesophageal junction adenocarcinoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastric cancer or gastroesophageal junction adenocarcinoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Gastric Cancer, Gastroesophageal Junction Cancer
- Gastric / Gastroesophageal Junction Adenocarcinoma
- Gastric or Gastroesophageal Junction Adenocarcinoma
- AFP Gastric or Gastroesophageal Junction Adenocarcinoma
- Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma
- Gastroesophageal Junction Adenocarcinoma
- Gastroesophageal-junction Cancer
- Metastatic Gastroesophageal Junction Adenocarcinoma
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.