Clinical trials
Gastric or Esophagogastric Junction Adenocarcinoma clinical trials
Below are recruiting gastric or esophagogastric junction adenocarcinoma clinical trials, each written for real people, not researchers. We’re tracking 925 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06767800RecruitingPhase 2
Study of TQB2102 with immunotherapy for HER2-positive gastroesophageal cancer
This trial tests a new combination of drugs (TQB2102, benmelstobart, and pembrolizumab) with or without chemotherapy for people with HER2-positive gastroesophageal cancer that cannot be removed by surgery or has spread. It aims to see if this combination is more effective than current treatments.
Fuyang, AnhuiAges 18–75 - NCT06732856RecruitingPhase 1/Phase 2
Zolbetuximab plus chemo before stomach cancer surgery
This trial tests a new drug called zolbetuximab combined with chemotherapy (docetaxel, oxaliplatin, S-1) before surgery for people with locally advanced stomach cancer that has a specific protein (CLDN18.2). The goal is to see if this combination shrinks tumors enough to improve surgery outcomes.
SeoulAges 19 years+ - NCT06768164RecruitingPhase 3
Comparing two stomach reconnection methods after cancer surgery
This trial compares two different ways to reconnect the stomach after removing the lower part for stomach cancer. It looks at which surgery leads to a better quality of life for patients.
ParisAges 18 years+ - NCT06702891Recruiting
Exosome study of gastric cardia cancer
This study looks at tiny particles called exosomes from your cancer cells to better understand gastric cardia cancer. It may help doctors find new ways to diagnose or treat this type of stomach cancer.
Jinan, ShandongAges 18 years+ - NCT06661668Recruiting
Stomach pacemaker implant for severe gastroparesis
This study tests whether placing a small, implanted device that sends gentle electrical pulses to the stomach can improve symptoms of severe gastroparesis—a condition where the stomach empties too slowly. It's for people whose symptoms haven't been controlled with other treatments and are significantly affecting their daily life.
Cologne, North Rhine-WestphaliaAges 18 years+ - NCT06666049Recruiting
Ultrasound test on the stomach before surgery in patients taking GLP-1 drugs
This trial uses a stomach ultrasound (called gastric POCUS) to check if your stomach is empty before surgery. It is for patients taking GLP-1 medications (like Ozempic, Wegovy, or similar) to help make sure it is safe to proceed with anesthesia.
Madrid, MadridAges 18–90 - NCT06291766Recruiting
Gestational diabetes after gastric bypass study
This study looks at how a continuous glucose monitor (CGM) can help manage blood sugar in pregnant women who have had gastric bypass surgery and now have gestational diabetes. It aims to find better ways to monitor and treat diabetes during pregnancy for women after this type of weight-loss surgery.
LundAges 18–50 - NCT06621979Recruiting
Study of fundoplicature after omega gastric bypass
This study checks if a second surgery to wrap the top of the stomach (fundoplicature) works well for people who had severe heartburn after a specific type of gastric bypass. If you had this second surgery in the last 2 years and your heartburn is better, you may be eligible.
CornebarrieuAges 18 years+ - NCT06610760RecruitingPhase 4
Ursodeoxycholic acid for stomach precancer reversal
This trial tests if ursodeoxycholic acid can reverse intestinal metaplasia (a precancerous stomach condition) in patients who have no H. pylori infection. The goal is to see if this medication can help lower the risk of stomach cancer.
Pingdingshan, HenanAges 18–75 - NCT06610266RecruitingPhase 4
Weifuchun tablet for stomach precancer reversal
This study tests if Weifuchun tablets can reverse precancerous changes called gastric intestinal metaplasia. If you have this condition and no H. pylori infection, you may qualify.
AnkangAges 18–75 - NCT06597227Recruiting
Partial vs total stomach removal for upper stomach cancer after chemo
This trial compares two types of surgery for upper stomach cancer after chemotherapy or radiation. It aims to see if removing only part of the stomach (proximal gastrectomy) works as well as removing the whole stomach (total gastrectomy) to help you recover better.
Wuhan, HubeiAges 18–75 - NCT06590454RecruitingPhase 2
Reversing stomach lining changes to lower cancer risk
This trial tests whether a treatment can reverse stomach lining changes called GIM that increase cancer risk. It's for people who have had a past H. pylori infection but no current stomach cancer, and whose GIM has certain high-risk features.
Durham, North CarolinaAges 18 years+ - NCT06580574RecruitingPhase 2
Immunotherapy to save the stomach or colon from surgery
This trial tests whether using immune checkpoint inhibitors alone (like checkpoint blockade drugs) can help people with certain gastric or colon cancers avoid surgery. It's for patients whose tumors have a specific genetic feature called dMMR/MSI-H and haven't spread to other parts of the body.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06567691Enrolling by invitation
Comparing two ways to bypass cancer-caused stomach blockage
This trial compares two ways to bypass a stomach or intestinal blockage caused by cancer that cannot be cured with surgery. It tests a newer, less invasive procedure (endoscopic gastroenterostomy) against the standard surgical bypass (gastrojejunostomy) to see which works better for patients like you.
Nashville, TennesseeAges 18 years+ - NCT06581120Enrolling by invitation
Stomach ultrasound study for diabetes and obesity
This study uses ultrasound to see how GLP-1 RA medications (like Ozempic) affect the stomach in people with type 2 diabetes and obesity. It may help doctors better understand how these medicines work.
Cincinnati, OhioAges 10–25 - NCT06534359Recruiting
Gastric vs transpyloric feeding for BPD
This study compares two ways of feeding premature babies with lung disease (BPD) who still need breathing support: feeding through a tube into the stomach (gastric) versus past the stomach into the small intestine (transpyloric). The goal is to see which feeding method helps these babies grow better and avoid problems.
Palo Alto, CaliforniaAges 1 month–1 year - NCT06519591RecruitingPhase 2
New drug combo for stomach cancer with abdominal spread
This trial tests a combination of three drugs (given through a vein and a pill) plus a chemotherapy infusion directly into your belly for stomach cancer that has spread to the lining of the abdomen. It specifically looks at a marker called Claudin 18.2 to see if this treatment works better for people with that marker.
Shanghai, Huangpu DistrictAges 18 years+ - NCT02823665RecruitingEarly Phase 1
Compare how bariatric surgery affects blood sugar changes
This early trial studies how blood sugar moves in people after certain weight-loss surgery compared with people without surgery. It may help researchers understand why blood sugar can drop too low and how treatments like atropine affect that process.
San Antonio, TexasAges 18–65 - NCT06495645Recruiting
Computer-aided endoscopy to find stomach growths
This trial tests a computer-aided system used during upper endoscopy to find stomach growths that might be missed. It may help improve detection of early stomach cancer or precancerous changes.
Hong KongAges 40 years+ - NCT06490159Recruiting
Predicting nerve damage from paclitaxel for stomach cancer
This study looks at whether a common chemotherapy drug called paclitaxel (Taxol) causes nerve damage (peripheral neuropathy) in people with advanced stomach cancer. The goal is to find out who is most likely to get this side effect, so doctors can better protect patients during treatment.
Kurashiki, Okayama-kenAges 20 years+ - NCT06487221RecruitingPhase 2
Avutometinib and Defactinib for diffuse stomach cancer
This trial tests two oral drugs, avutometinib and defactinib, for people with a specific type of stomach cancer called diffuse gastric cancer. The goal is to see if these drugs can help shrink or slow the cancer.
New York, New YorkAges 18 years+ - NCT06493032Recruiting
Gastric mapping to check G-POEM success
This study uses a non-invasive stomach-mapping test (BSGM) to see if a G-POEM procedure (a treatment for gastroparesis) works well. It may help doctors better understand how the stomach empties after the procedure.
Indianapolis, IndianaAges 18 years+ - NCT06468280RecruitingPhase 2
Immunotherapy and chemo with surgery for limited-spread stomach cancer
This trial tests a combination of an immunotherapy drug (PD-1 antibody) plus chemotherapy or targeted therapy, followed by surgery, for people with stomach cancer that has spread to a limited number of other sites. The goal is to see if this approach can help shrink the cancer enough to make surgery more effective.
Shanghai, Shanghai CityAges 18–79 - NCT06454149Recruiting
Study of gastric MALT lymphoma
This study is looking at people with a rare stomach lymphoma (MALT lymphoma) or people with other stomach conditions. It aims to understand more about the disease and track outcomes over time.
Ansan-si, Gyeonggi-doAges 18–75
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Common questions
- Are there clinical trials for gastric or esophagogastric junction adenocarcinoma?
- Yes. Clin2 currently lists 925 recruiting gastric or esophagogastric junction adenocarcinoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastric or esophagogastric junction adenocarcinoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastric or esophagogastric junction adenocarcinoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Gastric / Gastroesophageal Junction Adenocarcinoma
- Adenocarcinoma of Esophagogastric Junction
- Gastric or Gastroesophageal Junction Adenocarcinoma
- AFP Gastric or Gastroesophageal Junction Adenocarcinoma
- Gastric Cancer or Gastroesophageal Junction Adenocarcinoma
- Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma
- Siewert Type II Adenocarcinoma of Esophagogastric Junction
- Gastric Adenocarcinoma
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.