Clinical trials
Gastroesophageal Reflux clinical trials
Below are recruiting gastroesophageal reflux clinical trials, each written for real people, not researchers. We’re tracking 61 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06928350Recruiting
Normal esophagus readings in healthy Indian adults
This trial is studying normal acid and fluid movement in the esophagus of healthy people in India. It will help doctors better understand what is typical, which may improve care for people with acid reflux or other swallowing issues.
Hyderabad, TelanganaAges 18–50 - NCT06783751Recruiting
New surgical method to reduce acid reflux after weight loss surgery
This trial tests a modified version of sleeve gastrectomy that aims to reduce the risk of acid reflux (GERD) after surgery. It is for people aged 18–65 with a BMI between 35 and 55 who already have some degree of GERD and are planning to have weight loss surgery.
Orange, CaliforniaAges 18–65 - NCT06687603Recruiting
Detecting Barrett's esophagus in people without heartburn
This study aims to screen for Barrett's esophagus in people who are getting a routine colonoscopy but do not have chronic heartburn. It uses a simple, non-invasive cell collection device (EsoCheck) to see if you might have Barrett's esophagus, which can increase the risk of esophageal cancer.
Aurora, ColoradoAges 50 years+ - NCT06660342Recruiting
Safety of vonoprazan in pregnant women study
This study looks at the safety of vonoprazan (a medicine for acid reflux) when taken during pregnancy. It follows pregnant women who took the drug and those who didn't, to see how it affects mothers and their babies.
Wilmington, North CarolinaAges 15–50 - NCT06534359Recruiting
Gastric vs transpyloric feeding for BPD
This study compares two ways of feeding premature babies with lung disease (BPD) who still need breathing support: feeding through a tube into the stomach (gastric) versus past the stomach into the small intestine (transpyloric). The goal is to see which feeding method helps these babies grow better and avoid problems.
Palo Alto, CaliforniaAges 1 month–1 year - NCT05976165Recruiting
Breath testing study for small bowel bacterial overgrowth
This study checks whether breath tests can help identify small intestinal bacterial overgrowth in people with reflux-like symptoms (heartburn or regurgitation). If you qualify, you may be asked to avoid certain medicines and treatments for a short time so the test results are accurate.
Jacksonville, FloridaAges 18 years+ - NCT05899842Recruiting
Compare daily versus symptom-based acid reflux medicine after POEM
This study tests whether taking a stomach acid–reducing medicine every day (a protein pump inhibitor, or PPI) works better than taking it only when symptoms happen after POEM for achalasia. It aims to prevent gastroesophageal reflux after the procedure.
MarseilleAges 18 years+ - NCT05697393Recruiting
Testing a pressure band to ease GERD throat and cough symptoms
This study tests whether using an “external Shaker pressure band” can reduce GERD symptoms that affect the throat and airway, like chronic cough, choking, or food coming back up. It also checks whether these people can safely tolerate the study measurements through the nose.
Milwaukee, WisconsinAges 18–85 - NCT05514769Recruiting
Surgery type comparison for early-to-mid stomach cancer
This trial compares two different stomach cancer surgeries after removing the tumor, to see which works better for patients with stomach adenocarcinoma. It may help determine the safest approach and best recovery outcomes for people whose cancer has not spread.
Nanchong, SichuanAges 18–85 - NCT04699591Recruiting
Domperidone for severe stomach movement problems
This trial looks at whether domperidone can help people ages 12–21 with symptoms from stomach not moving well when usual treatments haven’t worked. It’s designed for cases where other causes have been ruled out and patients are monitored for possible heart and hormone side effects.
Kansas City, MissouriAges 12–21 - NCT04506593Recruiting
GI Motility diagnosis registry for people with digestion movement problems
This trial is a registry, meaning it collects information about people being evaluated for problems with how the gut moves. It may help doctors better diagnose gastrointestinal motility disorders in the future.
Indianapolis, IndianaAges Any age - NCT04358146Recruiting
Test a new formula to reduce infant spit-up
This study tests whether a new anti-regurgitation infant formula can reduce how often your baby spits up, and whether babies tolerate it well. It may help families who are feeding with formula and seeing frequent regurgitation (spit-up).
NamurAges 2 weeks–4 months - NCT00260585Recruiting
Esophageal risk and tissue registry study
This study collects information and, if you already need blood tests or procedures, may take extra small tissue samples (biopsies) to better understand esophageal-related conditions. It may help researchers learn about risk and future management for people with certain esophagus or reflux-related diagnoses.
Pittsburgh, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for gastroesophageal reflux?
- Yes. Clin2 currently lists 61 recruiting gastroesophageal reflux studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastroesophageal reflux trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastroesophageal reflux trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.